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23861
Green sanctuaries: residential green and garden space and the natural environment mitigate mental disorders risk of diabetic patients
Published 2025-01-01“…This highlights the potential for local governments to enhance the sustainability of such interventions, grounded in public health and urban planning, through strategic planning initiatives. Graphical Abstract…”
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23862
Development of a Web-Based Intervention for Middle Managers to Enhance Resilience at the Individual, Team, and Organizational Levels in Health Care Systems: Multiphase Study
Published 2025-02-01“…MethodsAn observational study was conducted in 3 phases: design, validation, and pilot study. The study was initiated in February 2022 and concluded in June 2023. …”
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23863
Screening of West Siberian patients with primary congenital glaucoma for CYP1B1 gene mutations
Published 2020-12-01“…Consequently, in children with signs of increased intraocular pressure, molecular genetic analysis of the CYP1B1 gene is advisable for early diagnosis and timely initiation of PCG therapy.…”
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23864
Optimizing oral 3-hydroxybutyrate dosage using pharmacokinetic model to improve cognitive function and mood in healthy subjects
Published 2025-01-01“…Previous studies indicated that achieving a maximum concentration (Cmax) of 3-HB in plasma at 0.28 mM could initiate ketone metabolism in the brain; we hypothesized that attaining this Cmax would improve brain health.MethodsWe aimed to demonstrate the efficacy of an optimized single oral dose of 3-HB on cognitive function and mood through two clinical studies: a pharmacokinetic study and an efficacy study. …”
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23865
Efficacy and safety of NeoAdjuvant chemotherapy with or without tIslelizumab followed by debulking surgery for oVarian cancEr (NAIVE study) in China: study protocol of an open-labe...
Published 2025-02-01“…Introduction The prognosis for epithelial ovarian cancer (EOC) is exceedingly poor, with patients diagnosed with stage III/IV tumours typically offered cytoreductive surgery in conjunction with chemotherapy as a standard treatment option. …”
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23866
Effects of Carbonate Alkalinity on Antioxidants, Immunity and Intestinal Flora of <i>Penaeus vannamei</i>
Published 2024-12-01“…The functional prediction results of COG and KEGG showed that the functional abundance of RNA polymerase sigma-70 factor is direct bacterial or plastid core RNA polymerase and is specific to promoter elements that are situated 10 and 35 base-pairs upstream of transcription-initiation points—in the high carbonate alkalinity treatment group, this was higher than that in the control group. …”
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23867
Serum Levels of Epithelial-Derived Cytokines as Interleukin-25 and Thymic Stromal Lymphopoietin after a Single Dose of Mepolizumab in Patients with Severe Non-Allergic Eosinophilic...
Published 2019-01-01“…The bronchial epithelium has continuous contact with environmental agents initiating and maintaining airway type 2 inflammation in asthma. …”
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23868
Community perspectives regarding brain-computer interfaces: A cross-sectional study of community-dwelling adults in the UK.
Published 2025-02-01“…Conclusion: Despite strong interest in BCIs, particularly for medical applications, ethical concerns, safety and privacy issues remain significant highlighting the need for clear regulatory frameworks and ethical guidelines, as well as educational initiatives to improve public understanding and trust. …”
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23869
The relationship between physical activity and career decision-making self-efficacy in Chinese college students: the mediating roles of self-control and social anxiety
Published 2025-01-01“…This study aims to explore the relationships among physical activity, career decision-making self-efficacy, self-control, and social anxiety to provide new perspectives and directions for enhancing university students' career decision-making self-efficacy.MethodsWithin the framework of this research endeavor, a cohort of 1,955 university students (N = 1,955) from 14 universities distributed throughout China was surveyed. The initial data was entered and stored by means of Microsoft Excel. …”
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23870
Serial measurements in COVID-19-induced acute respiratory disease to unravel heterogeneity of the disease course: design of the Maastricht Intensive Care COVID cohort (MaastrICCht)
Published 2020-09-01“…Therefore, a major part of the data collection is aligned with an existing national intensive care data registry and two international COVID-19 data collection initiatives. Additionally, we create a flexible design, so that additional measures can be added during the ongoing study based on new knowledge obtained from the rapidly growing body of evidence. …”
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23871
Specific Features of the Formation and Development of Mediation in Foreign Countries with Anglo-Saxon and Romano-Germanic Legal Systems
Published 2020-02-01“…Using the epistemological method of the research, the author has defined the essence of mediation as a separate alternative way of resolving disputes, which was initiated in the 60-70s of the XX century in the United States of America. …”
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23872
Le port antique de Saintes/Mediolanum (Charente-Maritime)
Published 2020-12-01“…More recently, underwater and geophysical surveys carried out in 2013 and 2014, as well as an initial underwater survey evaluation carried out in the Charente river in 2015, led to the discovery of numerous wooden remains (piles, planks, etc.), suggesting the presence of various Roman riverbank structures, as well as the discovery of a stone structure approximately 3 m thick and over 100 m long, on the right bank of the river. …”
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23873
Influence of magma intrusion and contact distance onthermal effects of low-temperature oxidation processes in coal
Published 2024-12-01“…And the results showed that under different air supply conditions, compared with the original coal, the initial exothermic and thermal equilibrium temperature points in the low-temperature oxidation stage were advanced by 0.2−3.4 ℃ and 1.9−18.2 ℃ for strongly eroded, weakly eroded, and homogeneous high-order coals, the total exothermic capacity was increased by 1.72%−135.75%, and the apparent activation energy was reduced by 1.62%−69.02%, and the closer the metamorphic coal was to the magma intrusion, the more oxidizing and exothermic it was, and the shorter the natural ignition period was. …”
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23874
Soil-transmitted helminth infections and nutritional indices among children (5–9 years) and adolescents (10–12 years) in Calabar, Nigeria
Published 2025-01-01“…Conclusion These findings highlight the necessity for an integrated approach to STH management and nutrition initiatives in Nigeria.…”
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23875
Personalized neuron-specific enolase level based on EEG pattern for prediction of poor outcome after cardiac arrest
Published 2025-01-01“…Results Participants were 64 years old (IQR [53; 72,5]), and 74% were male. 83% were out-of-hospital CA and 48% were initial shockable rhythm. Electrographic seizures were observed in 5% and 8% of good and poor outcome patients, respectively (p = 0.50). …”
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23876
Outcomes of different surgical procedures for optic disc pit: a meta-analysis
Published 2024-05-01“…Results A total of 838 studies were initially identified as potentially relevant studies. …”
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23877
Identification of strengths and weaknesses of the healthcare system for persons living with rare diseases in Catalonia (Spain), and recommendations to improve its comprehensive att...
Published 2025-01-01“…Objectives The project “acERca las enfermedades raras” (in English: “bringing RDs closer”) is an initiative primary designed to generate a consensus by a multidisciplinary group of experts to detect the strengths and weaknesses in the public healthcare system concerning the comprehensive care of persons living with a RD (PLWRD) in the region of Catalonia, Spain, where a Network of Clinical Expert Units (Xarxa d’Unitats de Expertesa Clínica or XUEC) was created and is being implemented since 2015. …”
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23878
Priority effects, nutrition and milk glycan-metabolic potential drive Bifidobacterium longum subspecies dynamics in the infant gut microbiome
Published 2025-01-01“…Background The initial colonization of the infant gut is a complex process that defines the foundation for a healthy microbiome development. …”
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23879
Digital leadership in quantity surveying: unveiling key characteristics and their role in driving digital transformation
Published 2023-12-01“…Adaptability, visionary motivation, innovation, and urgency form a framework that guides leaders in managing digital transformation initiatives effectively. The study suggests fostering a learning culture, encouraging innovation, and instilling a sense of urgency in embracing digital changes. …”
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23880
Pegloticase and Methotrexate Cotherapy in Patients With Uncontrolled Gout With Prior Pegloticase Monotherapy Failure: Findings of an Open‐Label Trial
Published 2025-01-01“…These findings demonstrate the challenge of overcoming established antipegloticase antibodies and emphasize the importance of initiating immunomodulation before the first pegloticase exposure.…”
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