Predictive value of systemic immune inflammation index combined with coagulation index in traumatic coagulopathy in patients with severe trauma by Chen Wang, Yongyong Huang, Shiyun Liao, Jiming Song

“…Early identification of TIC and its risk factors is vital for initiating timely interventions. The systemic immune inflammation index (SII), a composite marker of inflammation and immune response, alongside conventional coagulation indices, may hold promise in predicting TIC. …”
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Patient satisfaction with a clinically integrated sleep apnea care model vs. the current sleep care paradigm by Gregory D. Salinas, Wendy Cerenzia, Brandon Coleman, Frances Thorndike, Samantha Edington, Heidi Riney

“…To understand the patient experience in these models of care, this study compared patient satisfaction between the traditional sleep care approach and a clinically integrated, comprehensive sleep care program.MethodsA survey was developed to understand differences in the patient experience with the two different care models with respect to: access to sleep care, including time from initial appointment to seeing a sleep specialist, referral and insurance process; ease of sleep testing process and receiving a diagnosis; adoption, quality of education, and training with CPAP; ongoing adherence support with CPAP, and quality of life. …”
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Pathogenic variants of TUBB8 cause oocyte spindle defects by disrupting with EB1/CAKP5 interactions and potential treatment targeting microtubule acetylation through HDAC6 inhibiti... by Hui Luo, Jianhua Chen, Cao Li, Tian Wu, Siyue Yin, Guangping Yang, Yipin Wang, Zhihan Guo, Saifei Hu, Yanni He, Yingnan Wang, Yao Chen, Youqiang Su, Congxiu Miao, Yun Qian, Ruizhi Feng

“…It also harmed the interaction between microtubules and CKAP5/TACC3, which are crucial for initiating microtubule nucleation. Attenuated Ran‐GTP pathway was also found in TUBB8‐D417N oocytes, leading to disrupted spindle assembly. …”
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Intraoperative Analgesia with Magnesium Sulfate versus Remifentanil Guided by Plethysmographic Stress Index in Post-Bariatric Dermolipectomy: A Randomized Study by S. E. Silva Filho, S. Dainez, M. A. M. C. Gonzalez, F. Angelis, J. E. Vieira, C. S. Sandes

“…Analgesia was obtained in the remifentanil group with remifentanil at an initial dose of 0.2 μg·kg−1·min−1 and in the magnesium sulfate group with magnesium sulfate 40 mg·kg−1 + 10 mg·kg−1·h−1. …”
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Accidental and Deliberate Self-Poisoning with Medications and Medication Errors among Children in Rural Sri Lanka by Kavinda Dayasiri, S. F. Jayamanne, C. Y. Jayasinghe

“…Potentially, interventions such as community educational initiatives, written safety warnings, increased use of child resistant containers, and enforcement of laws to bring down accidental medication poisonings need to be implemented, and their effectiveness should be evaluated.…”
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The genetic duet of concurrent RASAL1 and PTEN alterations promotes cancer aggressiveness by cooperatively activating the PI3K–AKT pathway by Xiaopei Shen, Jie Tan, Rengyun Liu, Guangwu Zhu, Lisa Rooper, Mingzhao Xing

“…These results suggest that RASAL1, like PTEN, is a critical player in negatively regulating the PI3K–AKT pathway; defect in RASAL1 causes RAS activation, thus initiating the PI3K–AKT pathway signaling, which cannot terminate with concurrent PTEN defects. …”
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Interventricular septal dissection secondary to acute inferior myocardial infarction: case series and literature review by Ping Chen, Xiuqin Wang, Yun Mou

“…Cardiogenic shock occurred after percutaneous coronary intervention. The initial several echocardiography of the local hospital and our hospital misdiagnosed it as interventricular septal rupture secondary to myocardial infarction. …”
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The burden of non-specific chronic low back pain among adults in KwaZulu-Natal, South Africa: a protocol for a mixed-methods study by Morris Kahere, Themba Ginindza

“…The distribution of CLBP in Africa is unclear.Methods and analysis The research will be conducted in two phases. The initial phase will be an observational, cross-sectional hospital-based study that will be recruiting 650 participants, to determine the prevalence and risk factors of CLBP. …”
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EVALUACIÓN DE UN SISTEMA DE ALIMENTACIÓN ORGÁNICO SOBRE EL DESEMPEÑO PRODUCTIVO DE LA TILAPIA NILÓTICA (Oreochromis niloticus) CULTIVADA EN ESTANQUES DE TIERRA by A. Bermúdez, A. P. Muñoz-Ramírez, G. A. Wills

“…Se utilizaron 1.324 juveniles de Tilapia nilótica (Oreochromis niloticus) cuyo peso inicial promedio fue de 161,9 ± 7,0 g, solo machos sexados manualmente, sin reversión hormonal. …”
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Terminologie et ontologie pour les humanités numériques : le cas des vêtements de la Grèce antique by Christophe Roche, Maria Papadopoulou

“…This article presents the results of a collaboration between a classical philologist and a terminologist initiated during an EU-funded research project on ancient Greek clothing (Marie Skłodowska Curie Actions Project Chlamys. …”
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Correlation between Quantitative 13C-Urea Breath Test and Helicobacter pylori Treatment Success in a Population-Based Cohort by Doron Boltin, Zohar Levi, Tsachi Tsadok Perets, Hemda Schmilovitz-Weiss, Rachel Gingold-Belfer, Ram Dickman, Iris Dotan

“…In order to isolate a naïve test-and-treat population who were unlikely to have undergone an initial endoscopy-based H. pylori test, we excluded patients > 45 years and those with a previous C13-UBT. …”
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Risk factors for ocular biological parameters in Chinese preschool children: a cohort study from the Beijing whole childhood eye study by Xi Qin, Yunyun Sun, Yunyun Sun, Shana Wang, Xiaolan Xie, Lei Gao, Huijian Li, Huijian Li, Ruihua Wei, Jing Fu, Jing Fu, Bidan Zhu

“…Therefore, this study aimed to investigate the effects of these factors on the AL, CR, and AL/CR ratio in children aged 3–6 years in Beijing.MethodsIn this 3-month study, initiated in November 2021, children aged 3–6 years from nine kindergartens in Beijing were randomly selected for ocular biological parameter measurements. …”
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First microscopic and molecular identification of Cryptosporidium spp. in fat sand rats (Psammomys obesus) in Egypt and their potential zoonotic implications by Sara Abdel-Aal Mohamed, Fatma A. S. Anwar, Ahmed Gareh, Marwa M. I. Ghallab, Remigio Martínez, Asmaa Aboelabbas Gouda, Fatemah Enad Alajmi, Hind Alzaylaee, Ignacio García-Bocanegra, Ignacio García-Bocanegra, Ehab Kotb Elmahallawy, Ehab Kotb Elmahallawy

“…The specific role of fat sand rats (Psammomys obesus) in the transmission of Cryptosporidium spp. in Egypt and the genotypic characteristics of the circulating species in these animals remain poorly understood.MethodsIn this study, a total of 150 individual fat sand rat stool samples were collected from the saline marsh periurban areas of Abu-Rawash, Giza, Egypt. The samples were initially screened for the presence of Cryptosporidium spp. using light and scanning electron microscopy to characterize the parasite’s oocysts. …”
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Potential and actual evapotranspiration and Landsat derived indices by P. Kumar, D. Deka, A. Yadav, Ashwani ., M. Kumar, J.P. Das, A. Singh, A. Gurjar

“…The findings of the study will contribute to the comprehension of essential elements of water cycles and water budgets, facilitating improved resource allocation for climate-resilient sustainable initiatives.…”
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Perianal Paget’s Disease: The 17-Year-Experience of a Single Institution in Taiwan by Yu-Chen Wang, Anna Fen-Yau Li, Shung-Haur Yang, Hsiu-Hsun Ma, Wen-Yih Liang

“…The colorectal cancers (CRCs) in secondary PPD cases were located in anorectal area for 9 patients while 4 were located in the rectum; 5, 2, 4, and 2 were in stages I, II, III, and in uncertain stage, respectively. The distant metastasis rates of CRC in the secondary PPD patients during follow-up were 40% (2/5), 0% (0/2), and 50% (2/4) for stages I, II, and III, respectively. …”
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Superior Mesenteric Artery Syndrome: Clinical, Endoscopic, and Radiological Findings by Emanuele Sinagra, Dario Raimondo, Domenico Albano, Valentina Guarnotta, Melania Blasco, Sergio Testai, Marta Marasà, Vincenzo Mastrella, Valerio Alaimo, Valentina Bova, Giovanni Albano, Dario Sorrentino, Giovanni Tomasello, Francesco Cappello, Angelo Leone, Francesca Rossi, Massimo Galia, Roberto Lagalla, Federico Midiri, Gaetano Cristian Morreale, Georgios Amvrosiadis, Guido Martorana, Marcello Giuseppe Spampinato, Vittorio Virgilio, Massimo Midiri

“…Furthermore, we compared the demographical, clinical, endoscopic, and radiological parameters of these cases with a control group consisting of 10 cases out of 2380 EGDS of initially suspected (but not radiologically confirmed) SMA over a follow-up 2-year period (2015-2016). …”
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Evaluation of high-value bioproducts production by marine endophytic fungus Arthrinium sp. FAKSA 10 under solid state fermentation using agro-industrial wastes by Mohammad J. Alsarraf, Fuad Ameen, Abdullah Alfalih, Zirak Sajjad

“…The optimal conditions for solid-state fermentation were a 10 d incubation, 1 mm particle size, 60% initial moisture, 28 °C temperature, and 2 × 107 CFU/mL inoculum size. …”
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Modulation of myeloid and T cells in vivo by Bruton’s tyrosine kinase inhibitor ibrutinib in patients with metastatic pancreatic ductal adenocarcinoma by Li Zhang, Matthew Crocker, Lawrence Fong, Lisa M Coussens, Charles D Lopez, Shamilene Sivagnanam, Meenal Sinha, Brandon Chen, Jaqueline Marquez, Alexander Cheung, Whitney Tamaki, Jacob Stultz, Kendra Todd, Courtney Betts, Madeline J Griffith, Isabelle Solman, Eric Liu, Denise Pener, Anne Fahlman, Erin Taber, Kimberly Lerner, Brindha Rajagopalan, Clarisha Ware, Mark Bridge, Johnson Vo, Hannah Dragomanovich, Julie Sudduth-Klinger, Gina Vaccaro, Margaret Tempero

“…Patients with partial clinical responses had more diverse T and B cell receptor repertoires prior to therapy initiation.Conclusion Ibrutinib monotherapy skewed the immune landscape both in the circulation and TME towards activated T cells, monocytes and DCs. …”
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The prevalence of small airways disease and association with handgrip strength in young Hispanic farmworkers by Yutong Dong, Pam Cromer, Debbie Layman, Michelle Altvater, Yanbin Dong, Haidong Zhu

“…SAD was defined as forced expiratory flow at 25–75% predicted of vital capacity (FEF25-75%predicted) ≤ 60% per literature and OLD defined as forced expiratory volume in 1 s/ forced vital capacity (FEV1/FVC) ratio < 70% per Global Initiative for Chronic Obstructive Lung Disease criteria. …”
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S100A8-CAMKK2-AMPK axis confers the protective effects of mild hypothermia against cerebral ischemia-reperfusion injury in rats by Dandan Zhang, Yuting Dai, Xiaoyan Xu, Fuguo Ma, Mingshan Wang, Weiwei Qin

“…By targeting the S100A8-initiated CAMKK2/AMPK signaling pathway, we may unlock a novel therapeutic intervention or develop a refined MH therapeutic strategy against cerebral IR injury.…”
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