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26861
Cabozantinib Resolves Bone Scans in Tumor-Naïve Mice Harboring Skeletal Injuries
Published 2014-10-01“…Neither the vascular endothelial growth factor receptor (VEGFR) inhibitor axitinib, the MET inhibitor crizotinib, nor the combination was capable of inhibiting 18 F-NaF accumulation at known bioactive doses. …”
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26862
Effect of electroacupuncture on vascular remodeling in rats with cerebral ischemia by regulating irisin based on VEGF/Akt/eNOS signaling pathway
Published 2025-02-01“…In addition, the EA group exhibited a significant reduction in cerebral infarct volume and impairment of neurobehavioral function, an increase in cerebral blood flow and microvascular diameter on the ischemic side, and significantly higher expression levels of FNDC5, brain-derived neurotrophic factor (BDNF), vascular endothelial growth factor (VEGF), protein kinase B (Akt), and endothelial nitric oxide synthase (eNOS). …”
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26863
Using Targeted Virotherapy to Treat a Resistant Ewing Sarcoma Model: From the Bedside to the Bench and Back
Published 2014-01-01“…In vivo, VSVΔM51 selectively infected and killed EWS and led to significant delay in tumor growth. Conclusion. This study has been designed to implement a translational link between the bedside and the bench, where a specific challenging clinical scenario guided this basic science research. …”
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26864
A simple and highly efficient protocol for 13C-labeling of plant cell wall for structural and quantitative analyses via solid-state nuclear magnetic resonance
Published 2025-01-01“…The protocol is based on a convenient and easy setup to supply both 13C-labeled glucose and 13CO2 using a vacuum-desiccator. …”
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26865
Effect of Drying Methods on the Phenolic Profile and Antioxidant Capacity of <i>Pithecellobium dulce</i> (Roxb.) Benth. Aril and Its Inhibitory Properties on Human SW480 Colon Aden...
Published 2025-01-01“…From this extract, the median lethal concentration (LC<sub>50</sub>) was determined to be 13.76 mg/mL, which represents the concentration necessary to inhibit the growth of half of the cancer cells of this cell line. …”
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26866
Beyond the Surface: Decoding Pityriasis Versicolor Through Clinical, Dermoscopic and Microbiological Exploration
Published 2025-01-01“…Out of the 115 KOH mount positive cases, 51 (44.3%) showed growth on fungal culture with Malassezia furfur being the most common species to be isolated in 18 patients. …”
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26867
Germline BRCA testing in Denmark following invasive breast cancer: Progress since 2000
Published 2025-01-01“…BRCA test rates were higher for oestrogen receptor-negative/human epidermal growth factor receptor 2-negative BC (25% in 2000–2005 vs. 38% in 2012–2017), and these findings were confirmed in multivariate regression models. …”
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26868
Isolation and Characterization of Indigenous <i>Acetobacter</i> Strains from Cashew Apple and Their Potential Use in Vinegar Production
Published 2025-01-01“…All the isolates were resistant to alcohol 15% (<i>v</i>/<i>v</i>) and grew well between pH 5.0 and 6.5. Their optimal growth temperatures varied between 27 °C and 37 °C, and only isolate OYA6 grew at a temperature of up to 40 °C. …”
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26869
Pretreatment with AM1241 Enhances the Analgesic Effect of Intrathecally Administrated Mesenchymal Stem Cells
Published 2019-01-01“…The expression of transforming growth factor-β1 (TGF-β1) was also analyzed in the dorsal root ganglion (DRGs) and spinal cord of CCI mice. …”
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26870
Severe Acute Respiratory Syndrome Coronavirus 2 Infection Symptoms in Pregnancy and Maternal and Neonatal Complications Due to COVID-19: A Systematic Review
Published 2023-04-01“…The main maternal consequences of COVID-19 were intensive care unit (ICU) admission, pre-term delivery, maternal death, pre-mature rupture of membranes, pre-eclampsia, intrauterine growth retardation and stillbirth. Neonatal ICU admission, newborn death, neonatal sepsis, low birth weight and respiratory distress syndrome, tachypnoea, asphyxia and pneumothorax were the most common outcomes of COVID-19 infection in offspring of pregnant subjects. …”
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26871
Therapeutic Effect of Traditional Chinese Medicine on a Rat Model of Branch Retinal Vein Occlusion
Published 2019-01-01“…The expression of the vascular endothelial growth factor (VEGF-α) was measured via western blotting and immunofluorescent staining. …”
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26872
An adjustable bio-sealing method for rock fracture leakage mitigation
Published 2025-01-01“…The RAM-based bio-sealing mechanism is attributed to the following four stages: (1) fixation of bacterial flocs onto the fracture surfaces, (2) precipitation of CaCO3 onto the fracture surfaces, (3) growth of pre-precipitated CaCO3 and adhesion of new-suspended CaCO3, and (4) bridging and clogging processes. …”
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26873
Preventive Effects of Intrauterine Injection of Bone Marrow-Derived Mesenchymal Stromal Cell-Conditioned Media on Uterine Fibrosis Immediately after Endometrial Curettage in Rabbit
Published 2020-01-01“…Based on the evaluation of histomorphometric indices, curettage with or without preventive injections increased the growth of endometrial layers. However, the amount of fibrotic tissue in the CM and the BM-MSC injection groups was the same as the normal control groups, and all were less than the curettage group. …”
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26874
Using the Circular Economy to Mitigate the Global Electronic Waste Challenge: A Systematic Literature Review Approach
Published 2024-12-01“…This systematic literature review evaluates how the knowledge economy and modernisation growth have contributed to the e-waste burden, and how the circular economy can mitigate environmental and health effects. …”
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26875
The potential role of differentially expressed tRNA-derived fragments in high glucose-induced podocytes
Published 2024-12-01“…KEGG pathway analysis revealed that tRFs may be involved in signaling pathways related to growth hormones, phospholipase D, the regulation of stem cell pluripotency, and T-/B-cell receptors. …”
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26876
Mathematical Modeling of Wax Deposition in Field-Scale Crude Oil Pipeline Systems
Published 2022-01-01“…The novelty of this work is to develop a mathematical model that incorporates water-in-oil emulsions, wax precipitation kinetics, molecular diffusion, and shear dispersion to enable accurate predictions of both the wax deposit growth rate and aging of the deposit. …”
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26877
Plant genome modification: from induced mutagenesis to genome editing
Published 2022-11-01“…The snowballing growth of scientific data obtained using modern techniques of genome editing (GE) calls for their critical evaluation and comparison against previously applied methods such as induced mutagenesis, which was a leading method of genome modification for many decades of the past century, and its application has resulted in a huge diversity of cultivars. …”
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26878
Prenatal stress and child development: A scoping review of research in low- and middle-income countries.
Published 2018-01-01“…Five studies analyzed outcomes later in infancy such as temperament and motor development, all showing significant results; and nine in childhood such as behavioral development, asthma, and physical growth, with eight showing significant results.<h4>Conclusions</h4>Results highlight the importance of prenatal stress on infant and child outcomes in LMICs. …”
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26879
Pharmacovigilance imbalance analysis of VEGFR-TKI-related taste and smell disorders
Published 2025-01-01“…The advent of targeted drugs such as vascular endothelial growth factor receptor-tyrosine kinase inhibitors (VEGFR-TKIs) has significantly extended the survival time of cancer patients, and thus widely used in clinical practice. …”
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26880
Electronic Playback Devices to Reduce Ungulates’ Attendance in an Olive Grove Farm in the Province of Florence (Italy)
Published 2025-01-01“…(1) Background: Human–wildlife conflict can lead to adverse consequences for both parties, particularly in areas with a high concentration of wild ungulates. …”
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