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2621
Enabling Environment for Early Childhood Development: A Narrative Study of Preschools in Nepal
Published 2020-05-01Article -
2622
A Case of Ignatzschineria indica Bacteremia following Maggot Colonization
Published 2017-01-01Get full text
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2623
EMPIRICAL INVESTIGATION OF POLICE HARASSMENT OF PRIVATE UNIVERSITY STUDENTS IN OGUN STATE, NIGERIA
Published 2023-08-01Get full text
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2624
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2625
Splenic Complications of Babesia microti Infection in Humans: A Systematic Review
Published 2020-01-01Get full text
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2626
Kreowanie wizerunku przedsiębiorstwa usługowego na rzecz budowania relacji w transferze technologii
Published 2013-06-01“…I to nie tylko z dawcami technologii, pośrednikami w transferze technologii czy innymi podmiotami jakkolwiek ten proces wspierającymi, ale także z klientami, którzy będąc bezpośrednimi odbiorcami efektów nowo wdrożonej technologii, decydują o ostatecznym sukcesie tego protechnologicznego przedsięwzięcia.…”
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2627
A range spread target detection algorithm based on polarimetric features and SVDD
Published 2023-10-01Get full text
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2628
Epigenetic drug screening identifies enzyme inhibitors A-196 and TMP-269 as novel regulators of sprouting angiogenesis
Published 2025-01-01“…In contrast TMP-269, a selective class IIa HDAC inhibitor, exhibited anti-angiogenic effects by downregulating angiogenesis-related proteins and upregulating pro-inflammatory signaling. …”
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2629
淀粉样前体蛋白胞内结构域对阿尔茨海默病模型小鼠神经发生和学习记忆的影响
Published 2024-09-01“…生物信息学结果显示,AICD参与调节AD发病进程中神经发生和学习记忆的靶点有1 723个,关键靶点有TP53、CTNNB1、Akt1、EGFR、SRC、EP300、HDAC1、STAT3、HSP90AA1和MAPK1;另外,KEGG通路注释分析发现PI3K-Akt、HIF-1等信号通路在AICD调节神经发生和学习记忆起关键作用。…”
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2630
UPLC-MS/MS Method for Givinostat in Rat Plasma: Development, Validation, in vivo Pharmacokinetics Study and in vitro Metabolic Stability Research
Published 2025-01-01“…Ruanjuan Zhan,1,* Yanan Liu,1,2,* Jun Wu,1,2 Yuxin Shen,1,2 Xinhao Xu,1,2 Guanyang Lin,1,2 Xiaocheng Chen1 1The First Affiliated Hospital of Wenzhou Medical University, Zhejiang, People’s Republic of China; 2School of Pharmaceutical Sciences, Wenzhou Medical University, Zhejiang, People’s Republic of China*These authors contributed equally to this workCorrespondence: Guanyang Lin; Xiaocheng Chen, Email 13867702133@163.com; cxcwzcn@139.comBackground: Givinostat, a potent histone deacetylase (HDAC) inhibitor, is promising for the treatment of relapsed leukemia and myeloma.Purpose: This study aimed to develop and verify a quick assay for the measurement of givinostat concentration using ultra-performance liquid chromatography tandem mass spectrometry (UPLC-MS/MS) with eliglustat as the internal standard (IS), establishing a basic pharmacokinetic profile for its pre-clinical application and metabolic stability in vitro.Methods: Sample preparation was performed via protein precipitation using acetonitrile. …”
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2631
Valutazione della capacità di rientro alla base di un elicottero in presenza di danno balistico ad un albero di trasmissione della linea rotore di coda
Published 2013-04-01“…In questo articolo è quindi proposto uno studio sperimentale, suddiviso in diverse fasi, riguardante la verifica della capacità di un elicottero di portare a termine una missione di rientro alla base a potenza ridotta e in presenza di danneggiamento balistico ad un albero di trasmissione della linea rotore di coda. Il lavoro ha richiesto dapprima l’esecuzione, su esemplari del componente in esame, di prove sperimentali di impatto balistico, condotte utilizzando un proiettile calibro 7.62 NATO. …”
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2632
JAŠA TOMIĆ ‒ POLITIKA I IDEOLOGIJA
Published 2020-08-01“…Tomićeve političke koncepcije, ideje i delatnost su od esencijalnog značaja za razumevanje srpskog pitanja u Habzburškoj monarhiji. Beskompromisan borac, rečit, oštrog pera i izraza Tomić nije štedeo svoje političke protivnike i suparnike. …”
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2633
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2635
Leading the way – presence of brown bear Ursus arctos, lynx Lynx lynx and grey wolf Canis lupus underlines the integrity and corridor function of the upper Neretva Valley in Bosnia...
Published 2023-12-01“… Despite its connecting character to the Sutjeska National Park in the North-East, the course of the upper Neretva (Ulog and Borač valley) in Bosnia and Herzegovina (BiH), has to date not been an area of focus for carnivore research. …”
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2636
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2637
Design of Interference-Resilient Medium Access for High Throughput WLANs
Published 2015-10-01Get full text
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2638
Extremophilic Exopolysaccharides: Bioprocess and Novel Applications in 21st Century
Published 2025-01-01Get full text
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2639
Valutazione della capacità di rientro alla base di un elicottero in presenza di danno balistico ad un albero di trasmissione della linea rotore di coda
Published 2013-04-01“…In questo articolo è quindi proposto uno studio sperimentale, suddiviso in diverse fasi, riguardante la verifica della capacità di un elicottero di portare a termine una missione di rientro alla base a potenza ridotta e in presenza di danneggiamento balistico ad un albero di trasmissione della linea rotore di coda. Il lavoro ha richiesto dapprima l’esecuzione, su esemplari del componente in esame, di prove sperimentali di impatto balistico, condotte utilizzando un proiettile calibro 7.62 NATO. …”
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2640
Marcadas pela resistência: os casos das livrarias Jinkings (PA) e Palmarinca (RS)
Published 2023-01-01Get full text
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