KEAP1 mutations as key crucial prognostic biomarkers for resistance to KRAS-G12C inhibitors by Linyan Tian, Chengming Liu, Sufei Zheng, Huiyang Shi, Fang Wei, Wenxin Jiang, Yucheng Dong, Haiyan Xu, Enzhi Yin, Nan Sun, Jie He, Yan Wang

“…Comparative analysis of differentially expressed genes in KEAP1 knockout cells versus controls, utilizing GO, KEGG, and Reactome pathway analyses, revealed substantial enrichment in pathways linked to extracellular matrix organization and cell adhesion processes. Although STK11 mutations and heightened PD-L1 expression indicated a trend toward poorer outcomes, these correlations lacked statistical significance. …”
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بررسی روند بارش و دماهای کمینه و بیشینه استان آذربایجان شرقی با استفاده از مدل‌‌های جفت شده گزارش ششم (CMIP6)... by نازلی زنوزی علمداری, بهروز سبحانی, مهدی اصلاحی, مسیح اله محمدی

“…برای ارزیابی روند بارش، دما بیشینه و کمینه استان تا پایان قرن 21، از داده‌‌های 12 مدل (ACCESS-CM2، BCC-CSM2-MR، CESM2، CNRM-CM6-1، CanESM5، MIROC6، MRI-EMS2-0، IPSL-CM6A-LR، GISS-E2-1-G، HadGEM3-GC31- LL، NESM3 و NOR-ESM2-MM) از مجموعه مدل‌‌های در دسترس CMIP6 با سه سناریوی (SSP1-2.6، SSP2-4.5 و SSP5-8.5) استفاده شد. …”
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Macular edema after retinal vein occlusions. Macular morphometry and chorioretinal hemodynamics by A.A. Fil', E.L. Sorokin, O.V. Kolenko

“…The major cause of vision loss in RVOs is macular edema which results from subclinical inflammation characterized by leukostasis and enhanced expression of adhesion molecules and production of cytokines increasing retinal capillary permeability. …”
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Effect of periodontal therapy on endothelial function and serum biomarkers in patients with periodontitis and established cardiovascular disease: a pilot study by Ana Molina, Nagore Ambrosio, María Molina, Eduardo Montero, Leire Virto, David Herrera, Elena Figuero, Mariano Sanz

“…Endothelial function (flow-mediated dilation [FMD]) and carotid intima-media thickness (cIMT) at baseline, 3 and 6 months, and serum markers of inflammation and cell adhesion at 3 days, 10 days, 3 and 6 months after therapy, were evaluated. …”
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Advancing the Indian cattle pangenome: characterizing non-reference sequences in Bos indicus by Sarwar Azam, Abhisek Sahu, Naveen Kumar Pandey, Mahesh Neupane, Curtis P Van Tassell, Benjamin D Rosen, Ravi Kumar Gandham, Subha Narayan Rath, Subeer S Majumdar

“…These protein-coding genes were enriched for functions such as chemical synaptic transmission, cell junction organization, cell-cell adhesion, and cell morphogenesis. The protein-coding genes were found in various prominent quantitative trait locus (QTL) regions, suggesting potential roles of BICIs in traits related to milk production, reproduction, exterior, health, meat, and carcass. …”
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Caracterización de las mujeres que demandan interconsulta de psicología por violencia by Alain Darcout Rodríguez

“…Las variables analizadas fueron: distribución de mujeres según: edad, nivel de instrucción, ocupación, relación con el agresor, lugar de procedencia, tipo de violencia recibida, frecuencia y motivo de la agresión, medidas adoptadas y consecuencias de la violencia. …”
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TIGIT inhibitor M6223 as monotherapy or in combination with bintrafusp alfa in patients with advanced solid tumors: a first-in-human, phase 1, dose-escalation trial by Wei Gao, Ping Hu, Aung Naing, Meredith McKean, Anthony Tolcher, Lillian L Siu, Keyvan Tadjalli-Mehr, Anja Victor, Emilia Richter, Marco A F Nogueira Filho, Thomas Kitzing, Stephan Gleicher, Daniel Holland

“…Additional objectives included pharmacokinetics, pharmacodynamics and clinical activity (NCT04457778).Results Two dose-limiting toxicities were observed: grade 3 adrenal insufficiency (Part 1A: M6223 900 mg every 2 weeks) and grade 3 anemia (Part 1B: M6223 300 mg, only BA related). …”
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Genetic profiling of multidrug-resistant Acinetobacter baumannii from a tertiary care center in Malaysia by Aisyah Syakirah Shahari, Navindra Kumari Palanisamy, Fadzilah Mohd Nor

“…These STs are associated with acquired blaOXA-23, indicating an evolutionary adaptation of A. baumannii within the hospital setting.IMPORTANCEAcinetobacter baumannii is a ubiquitous Gram-negative coccobacillus bacterium that is primarily associated with nosocomial infections that can colonize biotic and abiotic surfaces to enhance cell-to-cell adhesion, ensuring the establishment of infections. …”
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Kinomic profiling to predict sunitinib response of patients with metastasized clear cell Renal Cell Carcinoma by Jeannette C. Oosterwijk-Wakka, Liesbeth Houkes, Loes F.M. van der Zanden, Lambertus A.L.M. Kiemeney, Kerstin Junker, Anne Y Warren, Tim Eisen, Ulrich Jaehde, Marius T Radu, Rob Ruijtenbeek, Egbert Oosterwijk

“…Unsupervised hierarchical clustering revealed 3 major clusters related to immune signaling, VEGF pathway, and immune signaling/cell adhesion. Basal kinase activity levels of patients with short PFS were substantially higher compared to patients who experienced extended PFS. …”
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Implementation of Accurate and Fast DNA Cytometry by Confocal Microscopy in 3D by Lennert S. Ploeger, André Huisman, Jurryt van der Gugten, Dionne M. van der Giezen, Jeroen A. M. Beliën, Abdelhadi Y. Abbaker, Hub F. J. Dullens, William Grizzle, Neal M. Poulin, Gerrit A. Meijer, Paul J. van Diest

“…Methods: Nuclear DNA was stained in 14 μm thick tissue sections of normal liver and adrenal stained with either YOYO-1 iodide or TO-PRO-3 iodide. …”
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Adipokines and Endothelium Dysfunction Markers in Pregnant Women with Gestational Hypertension by Elżbieta Poniedziałek–Czajkowska, Radzisław Mierzyński, Dominik Dłuski, Bożena Leszczyńska-Gorzelak

“…The aim of the study was to evaluate the levels of adipokines such as adiponectin and leptin as well as soluble intercellular adhesion molecule-1 (sICAM-1) and endogenous NOS inhibitor-asymmetric dimethylarginine (ADMA), as the endothelium dysfunction markers in pregnant women with gestational hypertension (GH). …”
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El apoyo social en el tratamiento de la diabetes en jóvenes by Lina Neri Espinoza Pire, Jhonny Alejandro Rodríguez Gutiérrez, María Ilusión Solís Sánchez

“…<strong>Fundamento:</strong> en diversas enfermedades crónicas, el apoyo social puede influir significativamente en la adhesión al tratamiento, la gestión de la enfermedad y el bienestar emocional. …”
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Mechanical Characterization of Nano-SiO₂-Reinforced Epoxy Sandwich Composites With 3D Rayon Graphite Felt Core and Woven Carbon Fiber Face Sheets by Zahraa Jalood Nayyef, Nabil Kadhim Taieh, Ammar A. Beddai, Ying Li, Xi Liu, Adil Elrayah

“…This method significantly enhances the toughness and adhesion between the fibers and the EP resin, resulting in superior mechanical properties. …”
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Deep learning radiomics nomogram for preoperatively identifying moderate-to-severe chronic cholangitis in children with pancreaticobiliary maljunction: a multicenter study by Hui-min Mao, Kai-ge Chen, Bin Zhu, Wan-liang Guo, San-li Shi

“…Abstract Background Long-term severe cholangitis can lead to dense adhesions and increased fragility of the bile duct, complicating surgical procedures and elevating operative risk in children with pancreaticobiliary maljunction (PBM). …”
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The Effect of Vascular Endothelial Growth Factor on Bone Marrow Mesenchymal Stem Cell Engraftment in Rat Fibrotic Liver upon Transplantation by Ke Yuan, Chunyou Lai, Lingling Wei, Tianhang Feng, Qinyan Yang, Tianying Zhang, Tao Lan, Yutong Yao, Guangming Xiang, Xiaolun Huang

“…We confirmed the expression of very late antigen-4 (VLA4, integrin α4β1) on rat BMSCs and the elevated expression of vascular adhesion molecule-1 (VCAM-1) in the hepatic sinusoidal endothelial cells. …”
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The Effects of Soft Tissue Flossing on Hamstring Range of Motion and Lower Extremity Power by Zachary Maust, Debbie Bradney, Sean M Collins, Caroline Wesley, Thomas G Bowman

“…This is hypothesized to improve flexibility by dissipating myofascial adhesions; however, research is lacking. # Objective To determine the effect of the application of a floss band to the thigh on hamstring flexibility and lower extremity power…”
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Elucidation of the mechanism of berberine against gastric mucosa injury in a rat model with chronic atrophic gastritis based on a combined strategy of multi-omics and molecular bio... by Lisheng Chen, Lisheng Chen, Xin Wang, Xin Wang, Jianyu Li, Lijuan Zhang, Wenbin Wu, Shizhang Wei, Wenjun Zou, Yanling Zhao, Yanling Zhao

“…Furthermore, 234 different expression genes were identified in the gastric tissue transcriptome, which were mainly involved in biological processes such as cell adhesion, angiogenesis, apoptosis, cell migration and lipids metabolism by regulating the MAPK signaling pathway. …”
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Associations of the Need for Surgery in Emergency Department Patients with Small Bowel Obstructions by Daniel J. Berman, Alexander W. Mahler, Ryan C. Burke, Andrew E. Bennett, Nathan I. Shapiro, Leslie A. Bilello

“…A known complication of surgery is the subsequent adhesions that can cause recurrent SBOs, longer hospital stays, and higher treatment costs. …”
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Effect of Different Surface Treatments on the Micro-Shear Bond Strength and Surface Characteristics of Zirconia: An In Vitro Study by Ann Sales, Shobha J. Rodrigues, M. Mahesh, Kishore Ginjupalli, Thilak Shetty, Umesh Y. Pai, Sharon Saldanha, Puneeth Hegde, Sandipan Mukherjee, Vignesh Kamath, Prashant Bajantri, N. Srikant, Ravindra Kotian

“…The mode of failure was majorly adhesive. The surface topography and surface roughness showed significant differences between the groups. …”
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Characterization and Study of Gene Expression Profiles of Human Periodontal Mesenchymal Stem Cells in Spheroid Cultures by Transcriptome Analysis by Takenori Suga, Michihiko Usui, Satoru Onizuka, Kotaro Sano, Tsuyoshi Sato, Kohji Nakazawa, Wataru Ariyoshi, Tatsuji Nishihara, Keisuke Nakashima

“…Cluster and Gene Ontology analyses revealed that genes involved in cell-cell adhesion as well as the G2/M and G1/S transitions of mitotic cell cycles were strongly expressed in the monolayer culture group. …”
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