Efficient Dual Cas9 Nickase Correction of a Prevalent Pathogenic LAMB3 Variant for Junctional Epidermolysis Bullosa by Alex du Rand, John Hunt, Daniel Verdon, Ben Buttle, P. Rod Dunbar, Diana Purvis, Vaughan Feisst, Hilary Sheppard

“…Dual-Cas9n–corrected JEB keratinocytes demonstrated restored laminin-332 expression and secretion in vitro, leading to improved cellular adhesion and accurate laminin-332 localization in engineered skin equivalents. …”
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Natural products based on Correa's cascade for the treatment of gastric cancer trilogy: Current status and future perspective by Wenhao Liao, Jing Wang, Yuchen Li

“…In phase I, NPs modulate Helicobacter pylori urease activity, motility, adhesion, virulence factors, and drug resistance, thereby inhibiting H. pylori-induced gastric mucosal inflammation and oxidative stress, and facilitating ulcer healing. …”
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Serum Matrix Metalloproteinase 9 and Macrophage Migration Inhibitory Factor (MIF) Are Increased in Young Healthy Nonobese Subjects with Positive Family History of Type 2 Diabetes by Agnieszka Nikołajuk, Natalia Matulewicz, Magdalena Stefanowicz, Monika Karczewska-Kupczewska

“…Hyperinsulinemic-euglycemic clamp was performed, and serum concentrations of monocyte chemoattractant protein-1 (MCP-1), interleukin 18 (IL-18), macrophage inhibitory cytokine 1 (MIC-1), macrophage migration inhibitory factor (MIF), matrix metalloproteinase (MMP-9), and soluble forms of adhesion molecules were measured. Relatives had markedly lower insulin sensitivity (p=0.019) and higher serum MMP-9 (p<0.001) and MIF (p=0.006), but not other chemokines and biomarkers of endothelial function. …”
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De la representación a la resistencia: autodefensa individual ante la violencia de género y racial by Claudia González Nieves

“…Al examinar la persistente caracterización de las mujeres como entidades vulnerables y el matiz racial que subyace en las interpretaciones visuales de la agresión, esta investigación cuestiona cómo estas representaciones se afianzan en la esfera mediática y política contemporánea. …”
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Role of CO2 Laser on SBS between Dental Porcelain and Composite Resin Repair Process by Noor Bader Hassan, Basima Mohammed Ali Hussein, Ahmed Ali Mohammed

“…The cohesive mode of failure was dominant in Groups I and III, whereas adhesive failure was dominant in Group II. Conclusion. …”
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A novel cytoprotective organ perfusion platform for reconstructing homeostasis of DCD liver while alleviating IRI injury by Tingting Lan, Mingxing Yu, Tao Ming, Hong Wang, Juan Deng, Shuhan Cheng, Zhongyang Shen, Deling Kong

“…Compared to the peristaltic pump, the BBGs significantly reduced cell apoptosis and morphological injury while enhancing cell proliferation and adhesion. Additionally, when the supernatant from ADSCs was introduced to LPS‐induced macrophages for 24 h, the BBGs group demonstrated a more pronounced anti‐inflammatory effect, characterized by reduced M1 macrophage expression. …”
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Exploring the Expediency of Waste Materials as Modifiers for Bitumen Mixes by Lukman Olaide Salami, Ifedolapo Omowumi Ameen, Afeez Adefemi Bello

“…The XRF revealed an enhancement in the adhesion and interlocking in the mineral structure. …”
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Worldwide variations in the knowledge and use of fluoroscopy during percutaneous nephrolithotomy—should we do better? A survey by the European Association of Urology Section for Ur... by Otaš Durutovic, Guohua Zeng, Bhaskar Somani, Simon Choong, Giorgio Mazzon, Di Gu, Zeeshan Hameed, TP Rajeev, Bogomir Milojevic, Davide Brusa, Tiago Ribeiro Oliveira, Sergio Pereira, Nariman Gadzhiev, Ali Serdar Gozen, Evangelos Liatsikos, Panagiotis Kallidonis, Uros Bumbasirevic, Andreas Skolarikos

“…Conclusion: Although high and routinary utilization of X-rays, the level of awareness and adhesion to “as low as reasonably achievable” principles among endourologists seems suboptimal in 65.0% of all respondents. …”
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Unphysiological lung strain promotes ventilation-induced lung injury via activation of the PECAM-1/Src/STAT3 signaling pathway by Gang Liu, Gang Liu, Bin-Bin Dong, Bin-Bin Dong, Zi-Heng Ding, Zi-Heng Ding, Chao Lan, Chang-Ju Zhu, Qi Liu, Qi Liu

“…Platelet endothelial cell adhesion molecule-1 (PECAM-1), a transmembrane receptor, senses mechanical signals. …”
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Electric field-assisted embedding of fiber optic sensors in structural materials for structural health monitoring by Xinchang Zhang, Joshua Daw, Charles Payne, Bibo Zhong, Austin Fleming, Zilong Hua, Jorgen Rufner

“…Microstructural characterization revealed excellent fiber-matrix adhesion and interdiffusion of elements across the interface. …”
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3D printed magnesium silicate/β-tricalcium phosphate scaffolds promote coupled osteogenesis and angiogenesis by Lulu Wang, Mingkui Shen, Zhongxin Tang, Jun Tan, Kuankuan Li, Haijun Ma

“…Achieving magnesium and silicon ions sustained release, 3D printed MS/β-TCP scaffolds possessed appropriate mechanical properties and had excellent biocompatibility that was suitable for osteoblastic MC3T3-E1 cells and human umbilical vein endothelial cells (HUVECs) with proliferation, adhesion, and migration. Combined techniques of Transwell co-culture, we studied the effect of MS/β-TCP scaffold activated cell-level specific regulatory network, which promotes the osteogenic differentiation of MC3T3-E1 and the endothelial formation of HUVEC by significantly up-regulating the expression of related genes and proteins. …”
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Immunohistochemistry for (Pro)renin Receptor in Humans by Satoshi Morimoto, Noriko Morishima, Daisuke Watanabe, Yoichiro Kato, Noriyuki Shibata, Atsuhiro Ichihara

“…It was observed in thyroid follicular epithelial cells, hepatic cells, pancreatic duct epithelial cells, zona glomerulosa and zona reticularis of the cortex and medulla of the adrenal gland, proximal and distal tubules and collecting ducts of the kidney, cardiomyocytes, and skeletal muscle cells. …”
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Isolation and Characterization of <i>Lactobacillus gasseri</i> Strains from Women for Potential Vaginal Health Applications by Eui-Chun Chung, Jong Seo Lee, Hye Ji Lim, Seok-Jin Kim, Youn-Jee Chung, Kum-Joo Shin

“…Furthermore, BELG74 exhibited strong biofilm formation and adhesion capacity of 28.7% to HeLa cells, making it effective in colonizing the vaginal environment and suppressing pathogenic bacteria. …”
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Structure-guided identification of mitogen-activated protein kinase-1 inhibitors towards anticancer therapeutics. by Md Nayab Sulaimani, Shazia Ahmed, Farah Anjum, Taj Mohammad, Anas Shamsi, Ravins Dohare, Md Imtaiyaz Hassan

“…This pathway plays a crucial role in various cellular processes, including cell proliferation, differentiation, adhesion, migration, and survival. Besides, many chemotherapeutic drugs targeting the MAPK pathway are used in clinical practice, and novel inhibitors of MAPK1 with improved specificity and efficacy are required. …”
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Interplay between circulating von Willebrand factor and neutrophils: implications for inflammation, neutrophil function, and von Willebrand factor clearance by Alua Kuanyshbek, Hamideh Yadegari, Jens Müller, Nasim Shahidi Hamedani, Samhitha Urs Ramaraje, Johannes Oldenburg

“…Moreover, stimulated neutrophils exposed to purified plasma-derived VWF exhibited elevated expression of neutrophil surface markers CD45 and CD66b, indicative of altered neutrophil function related to cell adhesion, migration, and phagocytosis. These findings suggest that VWF binding can modulate neutrophil function, potentially influencing their role in immune responses and inflammation. …”
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Lactobacillus reuteri LR1 Improved Expression of Genes of Tight Junction Proteins via the MLCK Pathway in IPEC-1 Cells during Infection with Enterotoxigenic Escherichia coli K88 by Hongbo Yi, Li Wang, Yunxia Xiong, Zhilin Wang, Yueqin Qiu, Xiaolu Wen, Zongyong Jiang, Xuefen Yang, Xianyong Ma

“…It was found that L. reuteri LR1, in large part, offset the ETEC K88-induced increase in permeability of IPEC-1 cell monolayers and decreased the adhesion and invasion of the coliform in IPEC-1 cells. …”
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Effects of Tert-Butylhydroquinone on Intestinal Inflammatory Response and Apoptosis following Traumatic Brain Injury in Mice by Wei Jin, Hongbin Ni, Yuxiang Dai, Handong Wang, Tianyu Lu, Jun Wu, Jian Jiang, Weibang Liang

“…Intestinal mucosa apoptosis and inflammatory-related factors, such as nuclear factor kappa B (NF-κB), tumor necrosis factor-α (TNF-α), interleukin-1β (IL-1β), interleukin-6 (IL-6) and intercellular adhesion molecule-1 (ICAM-1), were investigated at 24 h after TBI. …”
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Fibrothorax and Severe Lung Restriction Secondary to Lupus Pleuritis and Its Successful Treatment by Pleurectomy by Sat Sharma, Robert Smith, Fahad Al-Hameed

“…On pathology, pleuritis with vascular pleural adhesions was found. No lupus pneumonitis was noted. …”
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Analysis and Verification of a Slope Steering Model of TRVs in Hilly and Mountainous Environments by Luojia Duan, Kaibo Kang, Shiying Chen, Zixing Du, Longhai Zhang, Zhijie Liu, Fuzeng Yang, Zheng Wang

“…Compared to wheeled vehicles, tracked robotic vehicles have less ground pressure, greater traction adhesion, and stronger climbing and obstacle crossing capabilities, making them suitable for agricultural production in hilly areas. …”
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Two Novel CYP11B1 Gene Mutations in Patients from Two Croatian Families with 11β-Hydroxylase Deficiency by Katja Dumic, Tony Yuen, Zorana Grubic, Vesna Kusec, Ingeborg Barisic, Maria I. New

“…Steroid 11β-hydroxylase deficiency (11β-OHD) is the second most common cause of congenital adrenal hyperplasia. Mutations in the CYP11B1 gene, which encodes steroid 11β-hydroxylase, are responsible for this autosomal recessive disorder. …”
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