Examining the Effect of Consuming C8 Medium-Chain Triglyceride Oil for 14 Days on Markers of NLRP3 Activation in Healthy Humans by Helena Neudorf, Garett Jackson, Jonathan P. Little

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Clinical-epidemiological Characterization of Patients with Hypertensive Heart Disease by Milian Carralero Romero, Alián Pérez Marrero, Liliana Espinosa Castro

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Fatigue after subarachnoid haemorrhage: a study of patients with good clinical outcome by G. Makarevičius, K. Pilypaitė, G. Terbetas, G. Šustickas, G. Bulotienė

“…Mean general fatigue score was statistically significantly higher in patients with poorer condition on admission (defined as Hunt and Hess grade >2) (p=0.02) and in patients with a longer period after SAH (p=0.02). …”
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A Case of Tumour Twins: A Rare Presentation of Simultaneous Breast and Endometrial Malignancies by Sreenidhi Sreeram, Barathi Gunabooshanam, Vasugi Gramani Arumugam, Gouthaman

“…Grossly, the MRM specimen showed a single, grey-white, firm, infiltrative lesion measuring 2.2×2.2×1.5 cm in the lower central quadrant. Microscopy showed a neoplastic tissue composed of nests of tumour cells floating in lakes of abundant extracellular mucin. …”
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Prospective cohort study of voice outcomes following secondary tracheoesophageal puncture in gastric pull-up reconstruction after total laryngopharyngoesophagectomy by Emily C. Deane, Harman Parhar, Linda Rammage, Amanda Hu, Donald W. Anderson

“…Most patients self-reported an abnormal voice handicap-10 [median 26.5 (IQR 22.8–35.0)]. Conclusion Secondary tracheoesophageal puncture is a safe and feasible option for voice rehabilitation after gastric pull-up. …”
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Vesicoureteral Reflux in Children with Accidental Diagnosis of Unilateral Small Size Kidney by Mohsen Mohammadi, Khadijeh Ebrahimi, Soraya Khafri, Maryam Nikpour, Hadi Sorkhi

“…The predominant causative microorganism for UTIs was Escherichia coli (55.6%), with Klebsiella (22.4%) and Enterobacter (22.4%) accounting for the remaining cases. …”
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Investigation of Moral Literacy Levels of University Students (The Case of Mus Alparslan University) by Fatma BİLDİRİCİ, Teceli KARASU

“…The data obtained from the study was analyzed with the SPSS 22 statistical package program. Cronbach Alpha internal consistency coefficient was used in the reliability analysis of the scale. …”
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Comparing the efficacy of 3D-printing-assisted surgery with traditional surgical treatment of fracture: an umbrella review by Lin Xiao, Peiyuan Tang, Shengwu Yang, Jingyue Su, Wenbo Ma, Han Tan, Ying Zhu, Wenfeng Xiao, Ting Wen, Yusheng Li, Shuguang Liu, Zhenhan Deng

“…The Measurement Tool to Assess Systematic Reviews (AMSTAR) 2 was used to rate the quality and reliability of the meta-analyses (MAs), and Grading of Recommendations Assessment, Development, and Evaluation (GRADE) was used to grade the outcomes. …”
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Bexarotene-induced hypothyroidism and dyslipidemia; a nation-wide study by Katsunori Manaka, Junichiro Sato, Yusuke Hikima, Hirofumi Horikoshi, Maho Taguchi, Akimichi Morita, Hiraku Suga, Hikari Boki, Taku Fujimura, Yoji Hirai, Takatoshi Shimauchi, Chiharu Tateishi, Eiji Kiyohara, Ikko Muto, Hideki Nakajima, Riichiro Abe, Kazuyasu Fujii, Chikako Nishigori, Eiji Nakano, Kentaro Yonekura, Takeru Funakoshi, Masahiro Amano, Tomomitsu Miyagaki, Reiko Yamashita, Makoto Sugaya, Toshihisa Hamada, Masaomi Nangaku, Taroh Iiri, Noriko Makita

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First-in-human dose escalation trial to evaluate the clinical safety and efficacy of an anti-MAGEA1 autologous TCR-transgenic T cell therapy in relapsed and refractory solid tumors by Ignacio I Wistuba, Mamta Kalra, Linus Backert, Martin Wermke, Edwin R Parra, Jason John Luke, Apostolia M Tsimberidou, Sebastian Bunk, Mohammad B Hossain, Andrea Mayer-Mokler, Arun Satelli, Norbert Hilf, Steffen Walter, Cedrik M Britten, Van K Morris, Tobias A W Holderried, Winfried H Alsdorf, Katrin Wetzko, Borje S Andersson, Sandra Grund-Gröschke, Katrin Aslan, Anantha Marisetty, Swapna Satam, Jens Hukelmann, M Alper Kursunel, Karine Pozo, Andreas Acs, Melissa Baumeister, Claudia Wagner, Oliver Schoor, Ali S Mohamed, Delfi Krishna

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Therapeutic Efficacy of Moxibustion with Seed-Sized Moxa-Cone at Jing Acupoint on Limb Spasticity after Stroke： A Meta-Analysis by ZHANG Jinfei, JIANG Jiahui, TANG Jiqin

“…Meta-analysis results showed that, (1) The spasticity improvement rate: compared with the control group, the effective rate of the experimental group was significantly higher [<italic>OR</italic>=3.96, 95% <italic>CI</italic> (1.25,12.53), <italic>Z</italic>=2.34, <italic>P</italic>=0.02]. (2) MAS grade: compared with the control group, the grade of spasticity of the experimental group was significantly lower [<italic>RR</italic>=3.03, 95% <italic>CI</italic> (2.08, 4.41), <italic>Z</italic>=5.78, <italic>P</italic>&lt;0.000 01]. (3) CSI score: compared with the control group, CSI score of the experimental group was significantly lower [<italic>MD</italic>= -0.96, 95% <italic>CI</italic> (-1.26, -0.66), <italic>Z</italic>=6.20, <italic>P</italic>&lt;0.000 01]. (4) FMA score: compared with the control group, FMA score of the experimental group was significantly higher [<italic>MD</italic>=15.17, 95% <italic>CI</italic> (7.89, 22.46), <italic>Z</italic>=4.08, <italic>P</italic>&lt;0.000 1]. (5) BI score: compared with the control group, BI score of the experimental group was significantly higher [<italic>MD</italic>=5.95, 95% <italic>CI</italic> (4.38, 7.53), <italic>Z</italic>=7.39, <italic>P</italic>&lt;0.000 01].ConclusionMoxibustion with seed-sized moxa-cone at Jing acupoint can effectively improve the spasticity of limbs, reduce muscle tone, improve the motor function of limbs and quality of life of patients after stroke. …”
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Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) in People Living With HIV Attending Centre of Excellence in HIV Care at a Tertiary Level Teaching Hospital in North... by Ragini Ram, Anuradha Subramanian MD, MSc, FRCP, Rajeshwari K. MD, PhD, FRCPCH

“…Steatosis was identified as an increase in the echogenicity of the liver seen as an increase in the hepatorenal contrast and was further graded into the 3 grades of fatty liver. Out of the 30 subjects, 16.6% (5 out of 30) were found to have MASLD on USG, with grade 1 fatty changes seen in 4 (13.3%) and grade 2 fatty changes seen in 1 out of 30 subjects (3.3%). …”
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Faecal microbiota transplantation for patients with diabetes type 1 and severe gastrointestinal neuropathy (FADIGAS): a randomised, double-blinded, placebo-controlled trialResearch... by Katrine Lundby Høyer, Simon Mark Dahl Baunwall, Ditte Smed Kornum, Mette Winther Klinge, Asbjørn Mohr Drewes, Knud Bonnet Yderstræde, Louise Bruun Thingholm, Martin Steen Mortensen, Susan Mikkelsen, Christian Erikstrup, Christian Lodberg Hvas, Klaus Krogh

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Circulating CD3+CD8+ T Lymphocytes as Indicators of Disease Status in Patients With Early Breast Cancer by Han‐Kun Chen, Yi‐Ling Chen, Wei‐Pang Chung, Zhu‐Jun Loh, Kuo‐Ting Lee, Hui‐Ping Hsu

“…Diminished CD3+CD8+ CTL levels correlated with advanced cancer grade, extensive intraductal components, and positive lymphatic tumor emboli. …”
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Efficacy of Neoadjuvant Chemotherapy DOX and XELOX Regimens for Patients with Resectable Gastric or Gastroesophageal Junction Adenocarcinoma by Yuan Tian, Qun Zhao, Yong Li, Liqiao Fan, Zhidong Zhang, Xuefeng Zhao, Bibo Tan, Dong Wang, Peigang Yang

“…The most common grade 3-4 adverse events in these three groups were neutropenia (32.3%, 30.4%, and 21.1%), leucopenia (21.5%, 22.8%, and 15.8%), nausea (15.1%, 16.3%, and 12.6%), and fatigue (10.8%, 7.6%, and 8.4%). …”
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Using CT imaging to identify sarcopenia as a risk factor for severe falls in older adults by Nadja Fries, Angeliki Kotti, Mischa Woisetschläger, Anna Spångeus

“…Results The severe fall group showed higher grade of sarcopenia compared to the non-severe fall group (SMI ratio of 71% vs. 83%, p = 0.041) as well as lower, though statistically non-significant, BMI and subcutaneous adipose tissue (SAT) (BMI 22 [20–24] vs. 24 [22–27] kg/m2, p = 0.108, and SAT 95 ± 70 cm² vs. 141 ± 94 cm², p = 0.124). …”
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DNA Damage Sensor γ-H2AX Is Increased in Preneoplastic Lesions of Hepatocellular Carcinoma by Yasunobu Matsuda, Toshifumi Wakai, Masayuki Kubota, Mami Osawa, Masaaki Takamura, Satoshi Yamagiwa, Yutaka Aoyagi, Ayumi Sanpei, Shun Fujimaki

“…In 40 (69.9%) of 58 cases with HCC, the labeling index (LI) of γ-H2AX was above 50% and was inversely correlated with the histological grade. Mean γ-H2AX LI was the highest in dysplastic nodule (74.1±22.1%), which was significantly higher than HCC (P<0.005). …”
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Potentialities and critical issues of liquid biopsy in clinical practice: An umbrella review by Nicola Veronese, Claudio Luchini, Stefano Ciriminna, Katia Spinelli, Santo Fruscione, Paola Mattiolo, Miriam Belluzzo, Veronica Messina, Lee Smith, Mario Barbagallo, Walter Mazzucco

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Applied research note: Predicting carcass portion weights for purebred turkey (Meleagris gallopavo) lines using a 2D imaging system by Shai Barbut, Emily M. Leishman, Ryley J. Vanderhout, Benjamin J. Wood, Christine F. Baes

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Sleep Quality Among a Sample of Medical Students and the Association with Academic Performance: An Updated Data by Abdulrahman Almalki, Moayad Shehata, Khaled Siddiqui, Hamzah Albulushi, Nawaf Alshehri, Ahmed Aldumri, Saeed Alghamdi, Aya Khasati, Siraj Omar Wali, Omar Ayoub

“…Academic performance was self-reported by students based on their grade point average. Of the 274 participants, 54.0% were males with a mean age of 22.81 years. …”
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