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Desmoplasia in Pancreatic Cancer. Can We Fight It?
Published 2012-01-01“…Herein we discuss such new developments to fight the desmoplastic reaction, including inhibitors of the epidermal growth factor, fibroblast growth factor, the hedgehog pathway, as well as new molecular targets like CD40 agonist and its effects on T cells, extracellular matrix modifying enzymes such as LOXL2 inhibitor and novel tumour penetrating peptides for delivery of drugs.…”
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Mathematical Modeling, Analysis, and Optimal Control of Corruption Dynamics
Published 2020-01-01“…From the numerical simulation, it was found that the integrated control strategy must be taken to fight against corruption.…”
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Between giants and windmills: Lulismo in the presidential elections of 2018
Published 2023-09-01“…The methodology used combines the observation of the types of ads with the analysis of the French matrix discourse, based mainly on the contributions of Charaudeau and Orlandi. …”
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Réflexions sur l’appropriation du théâtre historique élisabéthain par la scène britannique contemporaine : usages de Macbeth dans Thirteenth Night de Howard Brenton (1981) et Dunsi...
Published 2022-01-01“…This article deals with how Shakespeare can be used as a matrix, either accommodating or problematic, to shape past or present events into a historical perspective on the contemporary stage, and looks at two plays that are explicit adaptations of Macbeth, Howard Breton’s Thirteenth Night (1981) and David Greig’s Dunsinane (2010). …”
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Nanoparticle Therapy Is a Promising Approach in the Management and Prevention of Many Diseases: Does It Help in Curing Alzheimer Disease?
Published 2020-01-01“…Treatment of brain diseases is always limited by the physiological nature of the highly selective blood-brain barrier (BBB) and the electrostatic charge of the nanoporous extracellular matrix. Nanomedical application provides a promising drug delivery revolution for the treatment of neurodegenerative diseases (NDDs). …”
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Routine malaria vaccination in Africa: a step toward malaria eradication?
Published 2025-01-01“…This review examines the role of routine malaria vaccination in Africa as a key strategy toward malaria elimination, explores challenges and solutions for widespread vaccine implementation, and discusses future directions in the ongoing fight to eliminate malaria on the continent.…”
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Co-infection mathematical model for HIV/AIDS and tuberculosis with optimal control in Ethiopia.
Published 2024-01-01“…Thus, this study will aids in the fight against HIV/AIDS, TB, and their co-infection policy-makers and other concerned organizations.…”
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Current Treatment Regimens and Promising Molecular Therapies for Chronic Hepatobiliary Diseases
Published 2025-01-01“…Chronic hepatobiliary damage progressively leads to fibrosis, which may evolve into cirrhosis and/or hepatocellular carcinoma. The fight against the increasing incidence of liver-related morbidity and mortality is challenged by a lack of clinically validated early-stage biomarkers and the limited availability of effective anti-fibrotic therapies. …”
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Research on entity recognition and alignment of APT attack based on Bert and BiLSTM-CRF
Published 2022-06-01“…Objectives: In the face of the complex and changing network security environment, how to fight against Advanced Persistent Threat (APT) attacks has become an urgent problem for the entire security community. …”
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2022 ALUMINUM ALLOY COLD/HOT-ROLLED SHEETS STRENGTH AND ANISOTROPY ANALYSIS
Published 2018-01-01“…2022 alloy has some characteristics of high strength,resistance to damage,can strengthen aging,When used in the next generation of supersonic aircraft skin and armored fighting vehicles and other fields,hot rolled and cold rolled are distinguish due to the different incoming member shapes.After aging treatment,hot-rolled plates tensile and yield strength higher than cold rolled sheet,but its elongation decreased.Under the same kind of rolling state,the perpendicular to the rolling direction of tensile higher than the yield in the rolling direction,but,elongation is reduced.By optical and transmission electron microscopy find hot rolled sheet grain relatively small and recrystallized grains increase than cold rolled sheet.The precipitation of hot-rolled plate small,densely distributed in the aluminum matrix compared to sheet cold-rolled,in macro the reaction to the higher tensile strength and hardness.…”
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An antibacterial, antioxidant and hemostatic hydrogel accelerates infectious wound healing
Published 2025-01-01“…The results confirmed its positive effects in fighting bacterial infection, reducing inflammation and promoting wound healing. …”
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Identification of most motivating resource for estimation of social hierarchy in water buffaloes
Published 2023-11-01“…The number of physical (fighting, bunting, pushing) and non-physical (threatening, avoiding) interactions were higher (p<0.01) for concentrate (439.4±13.49, 368.8±12.16) than green fodder (126.6±9.49, 147.8±90) and foggers (36.90±7.22, 83.5±6.61). …”
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