Evaluation of pre-exposure vaccine effectiveness against mpox during the 2022–2023 mpox outbreak in the Madrid region (Spain): a test-negative design by José Francisco Barbas del Buey, Jesús Íñigo Martínez, Marcos Alonso García, Andrés Aragón Peña, Laura Montero Morales, Araceli Arce Arnáez

“…Introduction An appropriate vaccination approach is critical to control the current outbreak of mpox but there is little research providing information on its effectiveness, particularly under circumstances of limited vaccine availability.Methods Pre-exposure vaccination campaign in the Madrid region, with the modified vaccinia Ankara-Bavarian Nordic was indicated in the risk groups from 18 July 2022.To evaluate the vaccine effectiveness (VE) of a dose of third-generation smallpox vaccine against mpox in the context of pre-exposure prophylaxis, a population-based indirect cohort study (Broome method) also known as test-negative design (TND) was conducted in the Madrid region (6 751 251 inhabitants). …”
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Differences in expression profiles in malingant melanoma patients according to immunotherapy response by E. N. Lukyanova, M. S. Fedorova, E. A. Pudova, T. V. Nasedkina, E. V. Stepanova, K. M. Nyushko, A. Y. Popov, N. V. Koroban, A. A. Dmitriev, M. V. Kiseleva, A. V. Lipatova, A. S. Zasedatelev, A. V. Kudryavtseva

“…One of the most important branch of modern molecular genetics and biomedicine is the search for predictive markers that help choose the most effective way of treatment, drug and also determine its individual dosage. …”
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Expansion of phase uniqueness of projection methods when illuminated by sinusoidal pictures with different periods by V. I. Guzhov, I. O. Marchenko, G. A. Pozdnyakov, E. E. Serebryakova

“…To increase the region of phase uniqueness, it is necessary to choose close periods. However, in this case, the error in determining the profile increases. …”
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THE USE OF ARTIFICIAL INTELLIGENCE IN THE THERAPEUTIC MANAGEMENT OF PAPILLARY THYROID MICROCARCINOMA: A RANDOMIZED CONTROLLED TRIAL PROTOCOL by Ramona Elena Teiu, Tudor Florin Ursuleanu, Hlescu Cristian Stefan, Roxana Grigorovici, Andreea Roxana Luca, Maria Paula Comanescu, Alina Ionela Calin, Alexandru Grigorovici

“…Materials and methods The optimization of the method will consist in the development and training of artificial intelligence models, using AI algorithms in the diagnosis of papillary thyroid cancererol by accurately identifying pathological lesions and adenopathy and generating 3D images from 2D CT images. use the transfer function for opacity and color, grayscale from DICOM images projected in a three-dimensional space. [1]; [2] We also use artificial intelligence (AI), through the Generative Adversarial Networks (GAN) technique, which has proven to be effective in representing complex data distributions [2], as we do in this study. …”
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Comparative genetic analysis of blood and semen samples in sperm donors from Hunan, China by Chuan Huang, Li-Ming Chu, Bo Liang, Hui-Lan Wu, Bai-Shun Li, Shuai Ren, Mei-Ling Hou, Hong-Chuan Nie, Ling-Yin Kong, Li-Qing Fan, Juan Du, Wen-Bing Zhu

“…Except for one case that was slightly different, the rest simulated matching results for blood were all consistent with results for sperm.Conclusions It is reasonable to choose either blood or sperm for genetic screening in semen donors.…”
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Instrumental balance assessment in Parkinson's disease and parkinsonism. A systematic review with critical appraisal of clinical applications and quality of reporting by Andrea Merlo, Lorenzo Cavazzuti, Maria Chiara Bò, Francesco Cavallieri, Maria Chiara Bassi, Benedetta Damiano, Sara Scaltriti, Valentina Fioravanti, Giulia Di Rauso, Giulia Di Rauso, Giacomo Portaro, Franco Valzania, Mirco Lusuardi, Isabella Campanini

“…Missing reporting about the technical aspects employed to manage posturographic data and comprehensive instructions given to the patients further contributed to lower quality.DiscussionWe provided recommendations for enhancing the clinical transferability of studies on static posturography to assess pwPD, including (1) discussing the rationale for choosing the assessment protocols and posturographic parameters, (2) detailing the inclusion criteria and select appropriate samples, and (3) reporting all the technical information to replicate the procedures and computations.Systematic review registrationInternational Prospective Register of Systematic Reviews (PROSPERO) on 6th February 2024 (ID CRD42024500777), https://www.crd.york.ac.uk/prospero/display_record.php?…”
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New Horizons In The Treatment Of Metastatic Castrate Resistant Prostate Cancer by Zein El Amir

“…Medical students rarely choose to teach the subject after their medical school years.  …”
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Anatomy In The Undergraduate Medical Curriculum; Blending The Old And New by Ayesha Yousaf

“…Medical students rarely choose to teach the subject after their medical school years.  …”
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'Giustizia fatta': observations sur un registre des condamnés à mort (1471–1764) de la bibliothèque de Beccaria by Pierre Musitelli

“…Résumé On trouve dans les archives de Cesare Beccaria (1738–1794) un registre manuscrit inédit, rédigé en italien par différentes plumes anonymes, intitulé Elenco dei giustiziati in Milano: s’y étend sur plus de 200 pages la liste chronologique des exécutions publiques d’hommes et de femmes sur le territoire du duché de Milan, entre 1471 et 1764. …”
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Design of a TSR-based project learning strategy for biochemistry undergraduate teaching and research labs: a case study by Camille R. Reaux, Shelby A. Meche, Jordan M. Grider, Soundharya Dhanabal, Tarikul I. Milon, Feng Chen, Wu Xu

“…(ii) The skills-first and concept-second approach is used. (iii) Students choose the proteins based on their interests. (iv) Students are encouraged to learn from each other to promote student–student interactions. …”
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Effect of HA filler injection into the midface on the lower lid by Jungyeon Kim, Eun Young Ahn, Yekyoung Hwang, Sinhye Park, Kyoung-Jin Kang

“…Consequently, improvement of lower lid eversion and lifting of drooping eyelashes were observed. In conclusion, the filler injection method using the SAFI technique prioritizes correcting skeletal deformities, structurally supporting the lower lid, and yielding favorable results, as demonstrated in this study.…”
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A Prospective Study Comparing Two-Time Points of Thyroid Hormone Replacement during the Holy Month of Ramadan by Zeinab Dabbous, Buthaina Alowainati, Sara Darwish, Hamda Ali, Seleena Farook, Mariam Al Malaheem, Abeir Abdalrubb, Wajiha Gul, Wajiha Abu Haliqa

“…In both the groups, 95% of patients said it was convenient for them to take the medication at the assigned time. Conclusion. Choosing an optimal time for levothyroxine intake during the month of Ramadan remains a challenge. …”
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Mapping neuro-disabilities and their dimensions among under 5 years of age children in the southern agricultural corridor of Tanzania: a preliminary baseline survey by Peter M. Chilipweli, Namanya Basinda, Paul Alikado Sabuni, Fredy Hyera, Upendojackline Liana, Titus Robert Leeyio, Elias C. Nyanza, Awerasia Vera Ngowi

“…Multi-stage sampling was used to choose clusters and areas for the study. The Malawi Developmental Assessment Tool (M-DAT) was used to assess the children’s developmental levels. …”
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Influences of Different Drop Height Training on Lower Extremity Kinematics and Stiffness during Repetitive Drop Jump by I-Lin Wang, Yi-Ming Chen, Ke-Ke Zhang, Yu-Ge Li, Yu Su, Chou Wu, Chun-Sheng Ho

“…Therefore, coaches can choose different drop heights and training quantities for each person to better prevent lower extremity injury.…”
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Improving the integrity and reproducibility of research that uses antibodies: a technical, data sharing, behavioral and policy challenge by M. Biddle, P. Stylianou, M. Rekas, A. Wright, J. Sousa, D. Ruddy, M. I. Stefana, K. Kmiecik, A. Bandrowski, R.A. Kahn, C. Laflamme, E. M. Krockow, H.S. Virk

“…This interacts with the batch-to-batch variability of these biological reagents, and the paucity of available characterization data for most antibodies, making it more difficult for researchers to choose high quality reagents and perform necessary validation experiments. …”
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Kinetic simulation of uranium migration in granite fissure media of beishan, gansu, China: A case study based on the Laplace transform and inverse transform methods by Xianzhe Duan, Cong Du, Nan Li, Jiaxin Duan, Zhenping Tang

“…The following insights were obtained: (1) After 100,000 years, U-238 has a very limited diffusion depth in the matrix domain, with a diffusion range of only a few tens of millimeters, whereas it migrates relatively quickly in the fissure domain, with a maximum migration distance of about 1500 m. (2) Under the same migration time and distance, the relative concentration of nuclide U-238 in the fissure domain increases with larger gap width, hydraulic gradient, and diffusible area ratio, but decreases with higher rock porosity. (3) In the same time range, the rock masses with larger gap widths, hydraulic gradients, and diffusible area ratios have larger migration ranges, while those with higher porosities have smaller migration ranges. (4) While selecting a site for diposal of HLWs, it is recommended to choose rock masses in the granite area of Beishan with no fissures or few fissures; additionally, areas with smaller fissure widths, hydraulic gradients, and diffusible area ratios but higher rock porosity should be prioritized. …”
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PCA and PSO based optimized support vector machine for efficient intrusion detection in internet of things by Mutkule Prasad Raghunath, Shyam Deshmukh, Poonam Chaudhari, Sunil L. Bangare, Kishori Kasat, Mohan Awasthy, Batyrkhan Omarov, Rajesh R. Waghulde

“…Evaluating the veracity, exactness, and retrieval rate of different machine learning algorithms is crucial for choosing the most effective ones. The accuracy of the Intrusion Detection System (IDS) based on Particle Swarm Optimisation (PSO) is 98.5 percent. …”
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Data-driven machine learning approaches for simultaneous prediction of peak particle velocity and frequency induced by rock blasting in mining by Yewuhalashet Fissha, Prashanth Ragam, Hajime Ikeda, N. Kushal Kumar, Tsuyoshi Adachi, P.S. Paul, Youhei Kawamura

“…This work compares five machine learning models (XGBoost, Catboost, Bagging, Gradient Boosting, and Random Forest Regression) to choose the most efficient performance model. The performance evaluation of each five machine learning models demonstrates each model achieved a performance of more than 0.90 during the testing phase, there was a strong correlation observed between the actual and the predicted ones. …”
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Effects of excessive body fat on colostrum lipid patterns: overweight/obese vs. normal weight mothers by Qian Liu, Yan Liu, Di Yang, Yanpin Liu, Yan Liu, Weicang Qiao, Juncai Hou, Yaling Wang, Minghui Zhang, Kai Yang, Xiaofei Fan, Ziqi Li, Junying Zhao, Lijun Chen

“…However, the concentrations of palmitic acid-containing TAGs, linoleic acid-containing TAGs, dihomo-γ-linolenic acid-containing TAGs, and polar lipids and the ratio of TAGs containing n-6 fatty acid/n-3 fatty acid were significantly higher in the colostrum of OW/OB mothers than in that of NW mothers. …”
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Anatomic Variations Important for Dental Implantation in the Mandible—A Systematic Review by Zlata Rajkovic Pavlovic, Milos Stepovic, Marija Bubalo, Ivana Zivanovic Macuzic, Maja Vulovic, Nevena Folic, Jovana Milosavljevic, Valentina Opancina, Dobrivoje Stojadinovic

“…The results of this study can aid in choosing appropriate measurement points and give the gross picture, for clinicians, in therapy planning, considering all the landmarks of significance in the mandible.…”
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