Correlation between serum homocysteine level and clinicopathological factors of IgA nephropathy by Cai Xiao-fan, Huang Jie-bo, Xing Yue, Cai Xiu-feng, Li Xue-ling, Zhong Yi-fei

“…The AUC of Hcy in predicting T and A was 0.751 （95%CI：0.699-0.803） and 0.625 （95%CI：0.565-0.685）， respectively， with the optimal cut-off value of 15.04 μmol/L and 13.11 μmol/L， respectively （all P<0.05）.ConclusionsHcy level at renal biopsy is significantly correlated with sex， Alb， Scr， Cys C， T and A in patients with IgAN， showing a potential ability to predict associated damages.…”
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COVID-19 – if the cure is worse than the disease. The Italian chaos by Giuseppe FERRARI

“…On the contrary what has been enacted to fight the COVID-19 will end up in having caused more damages than the virus itself.…”

Explanation and validation of the coordination model of the marketing and sales department in the insurance industry in Iran by Alireza Jahed, Ehsan Abedi, Hamidreza Saeednia

“…In order to ensure the achievement of the goals, managers must pay attention to the causal conditions such as the implementation of the risk management dashboard, structural integration and coordination in the business, creating synergy in organizational decisions, recognizing the prerequisites for coordination between the two departments of marketing and sales in the form of background conditions or coordination challenges such as "partial prejudices, non-specialist human capital, conflict of interests, managers' taste, CEO's attitude, ethical considerations, unfavorable customer support when receiving damages and fulfilling the organization's obligations, as well as interfering conditions such as upstream documents, market conditions (market stakeholders), legal conditions, and competitive conditions. …”
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Designing an entrepreneurial model in the banking network with a digital technology approach by Afshin Nobakht, majid nasiri, parviz Saeedi

“…A questionnaire was used to collect data. AMOS software and Interpretive Structural Modeling (ISM) were used for data analysis. …”
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Effects of Hypoxia Stress on Biochemical Indices and Expression of Hypoxia-Related Genes in the Heart of Rainbow Trout (Oncorhynchus mykiss) by Jiuju MA, Jinqiang HUANG, Yongjuan LI, Shenji WU, Lu ZHAO, Yue ZENG

“…Hypoxic stress affected the cardiac metabolism of rainbow trout, which affected the normal metabolism level and caused damage. Under hypoxic stress, the rainbow trout were able to provide feedback regulation of hypoxic stress through the high expression pattern of hypoxic-related, which prevents the heart from being in a constant state of hypoxic stress, allowing the organism to quickly return to a stable state and perform its normal physiological function. …”
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Inflammatory Indices and MAFLD Prevalence in Hypertensive Patients: A Large-Scale Cross-Sectional Analysis from China by Shen D, Cai X, Hu J, Song S, Zhu Q, Ma H, Zhang Y, Ma R, Zhou P, Yang W, Hong J, Zhang D, Li N

“…Di Shen,1,&ast; Xintian Cai,2,&ast; Junli Hu,2 Shuaiwei Song,1 Qing Zhu,2 Huimin Ma,2 Yingying Zhang,2 Rui Ma,2 Pan Zhou,2 Wenbo Yang,2 Jing Hong,2 Delian Zhang,2 Nanfang Li2 1Graduate School, Xinjiang Medical University, Urumqi, Xinjiang, People’s Republic of China; 2Hypertension Center of People’s Hospital of Xinjiang Uygur Autonomous Region, Xinjiang Hypertension Institute, NHC Key Laboratory of Hypertension Clinical Research, Key Laboratory of Xinjiang Uygur Autonomous Region, Hypertension Research Laboratory, Xinjiang Clinical Medical Research Center for Hypertension (Cardio-Cerebrovascular) Diseases, Urumqi, Xinjiang, People’s Republic of China&ast;These authors contributed equally to this workCorrespondence: Nanfang Li, Hypertension Center of People’s Hospital of Xinjiang Uygur Autonomous Region, Xinjiang Hypertension Institute, NHC Key Laboratory of Hypertension Clinical Research, Key Laboratory of Xinjiang Uygur Autonomous Region “Hypertension Research Laboratory”, Xinjiang Clinical Medical Research Center for Hypertension (Cardio-Cerebrovascular) Diseases, No. 91 Tianchi Road, Urumuqi, Xinjiang, 830001, People’s Republic of China, Tel +86 8564818, Email lnanfang2016@sina.comObjective: Hypertension development and progression are largely influenced by inflammation, which plays a critical role by activating the immune system and causing damage to the vascular endothelium. Metabolic dysfunction-associated fatty liver disease (MAFLD) is also associated with chronic low-grade inflammation, which drives disease progression via metabolic imbalances and adipose tissue dysfunction. …”
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Risk Factors and Outcome of Sepsis in Traumatic Patients and Pathogen Detection Using Metagenomic Next-Generation Sequencing by Yiqing Tong, Jianming Zhang, Yimu Fu, Xingxing He, Qiming Feng

“…Once diagnosed with sepsis, patients should be given an appropriate empiric antimicrobial treatment followed by the specific antibiotic therapy based on blood culture due to its rapid progression to tissue damage and organ failure. In this study, we aimed to analyze the risk factors and outcome of sepsis in traumatic patients and to investigate the performance of metagenomic next-generation sequencing (mNGS) compared with standard microbiological diagnostics in post-traumatic sepsis. …”
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Establishing an Electrophysiological Recording Platform for Epidural Spinal Cord Stimulation in Neuropathic Pain Rats by Yang CT, Shyu BC, Lin WT, Lu KH, Lin CR, Wen YR, Chen CC

“…All device implantations or pUHF-SCS per se did not cause evident spinal cord damage. This safe and stable platform provides an in vivo rat model for SCS investigation of mechanisms of action and device innovation.Keywords: spinal cord stimulation, pulsed-ultrahigh-frequency, evoked local field potential, primary somatosensory cortex, anterior cingulate cortex…”
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Network Design and Route Analysis Using Outside Plant by Isaac Adjaye Aboagye, Nii Longdon Sowah, Wiafe Owusu-Banahene, Aryee Shaelijah, Margaret Ansah Richardson, Emmanuel Baah-Boadi

“…The design will help to reduce the cost of repairing damaged cables drastically. Also, the design methodology helped us to develop a backbone network to get closer to the various homes and premises. …”
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Interleukin-1 Receptor-Associated Kinase-3 Aggravates Neuroinflammatory Injury After Intracerebral Hemorrhage via Activation NF-&kappa;B/IL-17A Pathway in Mice by Wang J, Li Y, Tan C, Shao J, Tang W, Kong Q, Sheng W, Ding Z, Li F, Piao J, Lv D, Hu L, Wang Q, Jiang X

“…Jun Wang,1,&ast; Yulong Li,1,&ast; Chunyu Tan,1,&ast; Jinlian Shao,1 Weitai Tang,2 Quan Kong,3 Wenqianjun Sheng,1 Zhiquan Ding,1 Feng Li,1 Jifeng Piao,1 Dingyi Lv,1 Libin Hu,1 Qinghua Wang,1 Xiaodan Jiang1 1Neuromedicine Center, The National Key Clinical Specialty, The Engineering Technology Research Center of Education Ministry of China on Diagnosis and Treatment of Cerebrovascular Disease, Guangdong Provincial Key Laboratory on Brain Function Repair and Regeneration, The Neurosurgery Institute of Guangdong Province, Guangdong-Hong Kong-Macao Greater Bay Area Center for Brain Science and Brain-Inspired Intelligence, Zhujiang Hospital, Southern Medical University, Guangzhou, 510282, People’s Republic of China; 2Department of Neurosurgery, The People’s Hospital of Luoding & Affiliated Luoding Hospital of Guangdong Medical University, Luoding, 527200, People’s Republic of China; 3Neurosurgery Department of Zengcheng Campus, Nanfang Hospital, Southern Medical University, Guangzhou, People’s Republic of China&ast;These authors contributed equally to this workCorrespondence: Qinghua Wang; Xiaodan Jiang, Email wqh1123@126.com; jiangxiao_dan@163.comBackground: Neuroinflammatory reactions are crucial factors in secondary brain damage following intracerebral hemorrhage (ICH). Although previous studies have shown that IRAK3 is involved in immune responses, the potential effects of IRAK3 on ICH remain unclear.Methods: Collagenase IV–induced ICH mouse model. …”
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ANALISIS ZONA RAWAN GEMPA BUMI DI KABUPATEN BENGKULU SELATAN BERDASARKAN PERCEPATAN TANAH PUNCAK MENGGUNAKAN FORMULA KANAI by Giltro Kencoro, M Farid, Arif Ismul Hadi, Darmawan Ikhlas Fadli, Agung Sedayu

“…Determining the earthquake-prone zone of South Bengkulu Regency is essential to reducing earthquake damage. Therefore, short-period microtremor data recording was conducted at 65 points in the study area. …”
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Building resilient cattle through better management of buffalo health by Alfredo Sánchez, Merilio Montero

“…The high proportion of damage attributed to the live-stock sector is debatable compared to other sectors inherent to human development. …”
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The Usage of Garlic Extract (Allium sativum) to Cure Pangasius Fish (Pangasius hypophthalmus) Infected by Aeromonas hydrophylla by Muslim Muslim, Hotly Maraulina, Harry Widjajanti

“…The clinical symptom after cure and care as long as fourteen days indicated in control (without garlic extract has been found hard damage bodies organ and the mortality fish effect, but in treatments A1 (0.2 %), A2 (0.4 %), A3 (0.6 %), and A4 (0.8 %) recover after submerged with garlic extract. …”
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Rethinking Resources: The Critical Role of Recycling in the Mining Industry by Yudan Whulanza, Eny Kusrini, Akhmad Herman Yuwono, Sri Harjanto, Nofrijon Sofyan

“…This initiative represents a dual opportunity: mitigating the growing problem of e-waste— which saw nearly 57 million tonnes discarded in 2021 alone—and providing a source of critical materials without the extensive damage associated with traditional mining methods (Gulliani et al., 2023). …”
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Sistem Pelacakan Dokumen Berbasis Seluler dan Kode QR by Monanta Alfiareza, Nori Wilantika

“…First, an android-based mobile application that contains census/survey document reporting (the number of documents that have been filled in, the number of damaged documents, and the number of documents that have not been used). …”
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Retinal status in moderate myopia and age-related macular degeneration. Management strategies by L.K. Moshetova, I.B. Alekseev, I.V. Vorobyeva, Yu.A. Nam

“…In comorbid ocular disorders, severe defects and focuses of RPE atrophy, extensive areas of the IS/OS junction line damage, and drusen are seen among morphological abnormalities of the eye fundus. …”
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Administration of Sex Hormone Preparations as a Risk Factor in the Development of Intrahepatic Cholestasis of Pregnancy and Biliary Sludge in Pregnant Women by Yu. B. Uspenskaya, I. V. Kuznetsova, A. A. Sheptulin, N. V. Goncharenko, A. N. Gerasimov, M. M. Amiraslanova

“…In the presence of BS, ICP occurs with more severe liver damage, and the patients are inferior to respond to UDCA treatment. …”
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Integrating Bulk and Single-Cell Transcriptomic Data to Identify Ferroptosis-Associated Inflammatory Gene in Alzheimer&rsquo;s Disease by Zhou H, Peng Y, Huo X, Li B, Liu H, Wang J, Zhang G

“…FuRong Laboratory, Changsha, Hunan, 410078, People’s Republic of China, Email ghzhang@hunnu.edu.cn Jian Wang, The Institute of Reproduction and Stem Cell Engineering, School of Basic Medical Sciences, Central South University, Changsha, 410006, People’s Republic of China, Email 205106@csu.edu.cnBackground: Ferroptosis is a form of programmed cell death triggered by iron-dependent lipid peroxidation, characterized by iron accumulation and elevated reactive oxygen species (ROS), leading to cell membrane damage. It is associated with a variety of diseases. …”
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Agricultural Drought Assessment using Remote Sensing Data (Case study: Tuyserkan County) by Maedeh Malmir, Kamran Shayesteh, Iman Pazhouhan

“…Effective monitoring at the right moment can greatly reduce damage to agricultural production. The use of remote sensing and satellite imagery as effective tools for monitoring agricultural drought has gained significant attention from researchers. …”
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Co-Delivery of Dacarbazine and miRNA 34a Combinations to Synergistically Improve Malignant Melanoma Treatments by Ding B, Li M, Zhang J, Zhang X, Gao H, Gao J, Shen C, Zhou Y, Li F, Liu A

“…In addition, in vivo results indicated that Co-PHRD micelles can significantly inhibit tumor growth without causing significant damage to major organs.Conclusion: Co-delivery of DTIC and miRNA 34a via polypeptide micelles showed synergistic effects against MM, offering a new strategy for gene and chemotherapy.Keywords: nano micelle, DTIC, miRNA 34a, co-delivery, malignant melanoma…”
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