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17161
Computer-Aided Supporting Models of Customized Crack Propagation Sensors for Analysis and Prototyping
Published 2025-01-01“…The range of sensor technologies for structural health monitoring (SHM) systems is expanding as the need for ongoing structural monitoring increases. In such a case, damage to the monitored structure elements is detected using an integrated network of sensors operating in real-time or periodically in frequent time stamps. …”
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17162
Circ_0001084/miR-181c-5p/PTPN4 Axis Mitigates Cardiomyocyte Injury by Modulating the TLR4/NF-κB Pathway: Insights into Therapeutic Potential for Myocardial Reperfusion Injury
Published 2025-01-01“…Non-coding RNAs, including miRNAs, have been increasingly recognized for their roles in regulating cardiomyocyte responses to hypoxia/reoxygenation (H/R) injury. miR-181c-5p, in particular, has been implicated in inflammatory and apoptotic processes, suggesting its potential involvement in exacerbating cellular damage.Methods: This study combined bioinformatic and experimental techniques to investigate myocardial injury. …”
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17163
Pengaruh Timbal (Pb) Terhadap Kadar MDA Serum Tikus Putih Jantan
Published 2014-09-01“…Pb toxicityinhibitsan enzyme that acts as an antioxidant and liver cell damage.<br />The purpose of this study was to observe the effect of lead (Pb) on levels of malondialdehyde (MDA) male whiterats. …”
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17164
ECONOMIC ASPECT OF CRIMINAL LAW COUNTERACTION TO JUSTIFICATION OF ARMED AGGRESSION AGAINST UKRAINE: RISKS FOR THE STATE BUDGET IN THE LIGHT OF THE PRACTICE OF THE EUROPEAN COURT OF...
Published 2024-12-01“…The empirical basis of the study was as follows: (1) statistical data on Ukraine's participation as a defendant in the ECHR and the expenses incurred by it for the compensation of damages in 2019-2023; (2) approximately 900 verdicts of Ukrainian courts under Article 4362 of the Criminal Code; (3) the survey results of 4015 law enforcement officers of Ukraine on countering the glorification of the Russian armed aggression in Ukraine; (4) the survey results of 16 Ukrainian judges on countering the glorification of the Russian armed aggression in Ukraine; (5) 46 ECHR judgments. …”
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17165
Ilaser Submucous Destruction in the Treatment of Hemorrhoids
Published 2023-08-01“…The proposed method applying a fiber laser with a diode pump with a wavelength of 1940 nm makes it possible to affect transdermally the internal hemorrhoidal node without damaging the mucosa of the anal canal. The absence of postoperative wounds in the anal canal leads to a decrease in pain syndrome, and by day 7 there are no clinical manifestations of hemorrhoids. …”
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17166
Coup (d'etat) in the Baltic States (1926, 1934): Similarities and Differences
Published 2006-12-01“…The model enabled a more flexible reaction to the danger of extremist trends or serious blows to democracy; it also contributed to the protection from damaging impact of outward influences, which was especially noticeable in Estonia. …”
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17167
Choroidal Thickness in Eyes with Band Atrophy of the Optic Nerve from Chiasmal Compression
Published 2022-01-01“…The choroid does not thin after the inner retinal layer becomes damaged due to CCL and may even be thicker in some areas with corresponding severe retinal neural loss. …”
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17168
Y2O3NPs induce selective cytotoxicity, genomic instability, oxidative stress and ROS mediated mitochondrial apoptosis in human epidermoid skin A-431 Cancer cells
Published 2025-01-01“…This led to oxidative stress, along with severe damage to genomic DNA and mitochondrial membrane potential, triggering substantial apoptosis. …”
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17169
Hubungan Derajat Keasaman Cairan Lambung dengan Derajat Dispepsia pada Pasien Dispepsia Fungsional
Published 2016-08-01“…Gastric acid hypersecretion can increase the secretion of pepsin which can cause gastric mucosal damage in functional dyspepsia. The objective of this study was to determine the correlation of gastric juice acidity with dyspepsia level experienced by functional dyspepsia patients.This study was a analytic study with cross sectional design applied on 35 samples of functional dyspepsia patients with non-probability consecutive sampling technique at RSUP DR. …”
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17170
OUR EXPERIENCE IN TREATMENT OF ENTEROATMOSPHERIC FISTULAS FORMED AS A RESULT OF MINE-EXPLOSIVE INJURY
Published 2024-10-01“…However, 87% of all penetrating wounds of the abdominal cavity are accompanied by intestinal damage, which in the future can lead to the formation of enteroatmospheric fistulas. …”
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17171
SRT3025-loaded cell membrane hybrid liposomes (3025@ML) enhanced anti-tumor activity of Oxaliplatin via inhibiting pyruvate kinase M2 and fatty acid synthase
Published 2025-01-01“…This novel drug delivery system inhibits key metabolic pathways, which increase DNA damage and tumor cell apoptosis. The results indicate that 3025@ML is a promising therapeutic strategy for overcoming OXA’s compromised therapeutic effect and potentially improving cancer treatment outcomes.…”
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17172
Fungsi Tiroid Pasca Radioterapi Tumor Ganas Kepala- Leher
Published 2016-09-01“…Tinjauan Pustaka : Hipotiroid merupakan efek samping yang paling sering ditemukan pasca radioterapi tumor ganas kepala dan leher. …”
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17173
The effect of pharmaceutical composition based on L-carnitine on structural and functional features of rat placenta in the model of passive tobacco smoking
Published 2025-01-01“…The use of a pharmaceutical composition based on L-carnitine at a dose of 25 mg/kg in pregnant rats with a reproduced model of passive smoking reduces the damaging effect of cigarette combustion products on placental steroidogenesis. …”
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17174
Establishment and Evaluation of a Moderate-to-Severe Knee Osteoarthritis Model in Rats Induced by Surgery
Published 2024-12-01“…Immunohistochemical staining was used to detect the expression of type II collagen and matrix metalloproteinase 13 (MMP13), reflecting the anabolic and catabolic metabolism of the knee joint cartilage.ResultsThe knee joint cartilage in the 8-week and 20-week model groups was severely damaged, with Pelletier and modified Mankin's scores significantly higher than those in the sham surgery group (both P<0.01). …”
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17175
Hepatitis D virus infection triggers CXCL9-11 upregulation in hepatocytes and liver infiltration of CXCR3+ CD4 T cells
Published 2025-03-01“…Background & Aims: The role of hepatocytes in producing chemokines and triggering liver inflammation and damage in chronic hepatitis D (CHD) is not fully understood. …”
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17176
Association of IL-8 and CXCR2 with AST/ALT Ratio in Liver Abnormalities Screening during Oxidative Stress Injury Caused by VCM
Published 2024-01-01“…Liver impairment caused by VCM has been linked to irreversible damage such as fibrosis, necrosis, hepatocellular carcinoma, and liver angiosarcoma. …”
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17177
N88S seipin-related seipinopathy is a lipidopathy associated with loss of iron homeostasis
Published 2025-01-01“…Results In a well-established yeast model of N88S seipinopathy, misfolded N88S seipin forms IBs and exhibits higher levels of ER stress, leading to decreased cell viability due to increased reactive oxygen species (ROS), oxidative damage, lipid peroxidation, and reduced antioxidant activity. …”
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17178
Network Pharmacology Combined With Metabolomics Reveals the Mechanism of Yangxuerongjin Pill Against Type 2 Diabetic Peripheral Neuropathy in Rats
Published 2025-01-01“…Metabolomics results showed that the potential metabolic pathways of YXRJP in the treatment of DPN mainly involved amino acid metabolism such as arginine, alanine, aspartic acid, lipid metabolism and nucleotide metabolism.Conclusion: YXRJP can effectively improve the symptoms of DPN rats and reduce nerve damage. The effects are mainly related to reducing oxidative stress injury, promoting the expression of neuroprotection-related proteins, reducing the expression of inflammation-related proteins, and affecting amino acid metabolism, lipid metabolism, and nucleotide metabolism pathways. …”
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17179
Antagonistic Effects of Sublethal Concentrations of Certain Mixtures of Metal Oxide Nanoparticles and the Bulk (Al2O3, CuO, and SiO2) on Gill Histology in Clarias gariepinus
Published 2019-01-01“…In single exposure, the gill alterations include high frequencies of erosion of gill lamella (EGL), hypertrophy (HPT), oedema (OD), and necrosis (N). Less damage was observed at the combination of the metal oxide nanoparticles of SiO + Al2O3, SiO + CuO and SiO + Al2O3 + CuO in equal (1 : 1—HAI, 2 and 6; 1 : 1 : 1—HAI, 6) and unequal ratios (1 : 2—HAI, 16 and 6; 2 : 1—HAI, 8 and 6). …”
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17180
Editorial: The Artificial Intelligence in Translational Medicine and Biomedical Research, How Future Can be Shaped?!!
Published 2023-12-01“…In an in vitro world, these created cells could induce tissue damage recovery. The AI based medical diagnosis is also a revolutionary step toward proper diagnosis and consequently, medical intervention. …”
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