Exploring the alleviating effects of Bifidobacterium metabolite lactic acid on non-alcoholic steatohepatitis through the gut-liver axis by Hongmei Zhao, Hongmei Zhao, Juan Zhou, Lingzhi Yuan, Zhiyi Sun, Yi Liu, Xinyu Zhao, Feng Ye

“…In vitro, an NAFLD cell model was established using oleic acid, with cells treated with lactic acid and NLRP3 overexpression to assess lipid droplet accumulation and inflammation.ResultsIn vivo findings indicated that, in comparison to CBX group (Control group without antibiotic treatment), NAFLD/CBX group (NAFLD group without antibiotic administration) and NAFLD/ABX group (NAFLD group with antibiotic administration) exhibited increased liver-to-body weight ratio, higher lipid droplet accumulation, aggravated liver histopathological damage, and elevated levels of AST (Aspartate Aminotransferase), ALT (Alanine Aminotransferase), TC (Total Cholesterol), TG (Triglycerides), LDL-C (Low-Density Lipoprotein Cholesterol), IL-6 (Interleukin-6), TNF-α (Tumor Necrosis Factor-alpha), IL-1β (Interleukin-1 beta), and NLRP3-related molecules, while HDL-C (High-Density Lipoprotein Cholesterol) levels significantly decreased. …”
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Study on the Genetic Differences in Reservoir Characteristics Based on the Bidirectional Provenance of the Yanchang Formation in the Jiyuan Area, Ordos Basin, China by Qiang Tong, Zhaohui Xia, Jixin Huang, Junchang Wu, Yusheng Wang, Zheng Meng, Chaoqian Zhang

“…Although more dissolution improvements have been obtained, the damage to the reservoir caused by cementation in the middle and late stages is extremely fatal, while the chlorite film in the APA reservoir has a better protection effect on the primary intergranular pores. …”
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The intervention of curcumin on rodent models of hepatic fibrosis: A systematic review and meta-analysis. by Yun-Hang Chu, Bing-Yao Pang, Ming Yang, Qi Meng, Yan Leng

“…<h4>Conclusion</h4>The analysis results indicate that curcumin can reduce liver cell apoptosis by maintaining the stability of liver cell membrane, inhibit the activation and proliferation of hepatic stellate cells by reducing inflammatory response, and alleviate tissue peroxidation damage by clearing oxygen free radicals.…”
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CCR2 signaling regulates anti-chlamydia T cell immune responses in the airway. by Shuaini Yang, Jinxi Yu, Xue Dong, Jiajia Zeng, Lu Tan, Hong Zhang, Ruoyuan Sun, Yuqing Tuo, Jing Yang, Chunxiao Wan, Hong Bai

“…Conversely, ccr2-/- mice exhibit an exaggerated Th2-type immune response, with elevated levels of Th2-promoting cytokines (IL-4), transcription factors (STAT6 and gata3), and il-5, which together lead to more severe lung tissue damage and increased susceptibility to infection. …”
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Comparison of the Insertion Conditions and Haemodynamic Changes during I-Gel Insertion using Propofol, Ketamine-Propofol (Ketofol) and Thiopentone Intravenous Induction Agents: An... by Pooja Arpapan Shah, Aashi Nilesh Surti, Anupapama Kumari, Dinesh K Chauhan, Sara Mary Thomas

“…Introduction: The I-gel was designed to mitigate adverse reactions by providing the advantages of a secure airway without the complications associated with visualisation and tracheal intubation, specifically reducing the risk of barotrauma and vocal cord damage. Insertion requires a good induction agent and adequate depth of anaesthesia to achieve proper jaw relaxation and to prevent effects such as coughing, gagging, laryngospasm and any movements. …”
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Unilateral Toxic Anterior Segment Syndrome Resulting in Cataract and Urrets-Zavalia Syndrome after Sequential Uneventful Implantation of a Posterior Chamber Phakic Toric Intraocula... by Kepa Balparda, Claudia Marcela Vanegas-Ramirez, Johny Márquez-Tróchez, Tatiana Herrera-Chalarca

“…Although timely and correct management was instituted, upon resolution of TASS, the patient developed Urrets-Zavalia Syndrome, anterior subcapsular cataract, and significant endothelial damage in the same eye. Results. The patient was followed closely and managed accordingly; corneal edema and anterior segment inflammation of the right eye eventually resolved. …”
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HyProCure for Flatfoot Deformity: A Clinical Characteristics Analysis in China by Shaoling Fu, Chenglin Wu, Cheng Wang, Jiazheng Wang, Zhongmin Shi

“…Currently, Chinese surgeons and patients favor subtalar arthroereisis (SA) due to its minimally invasive and low‐damage characteristics. HyProCure device is widely used. …”
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Identifying key signs of motor neurone disease in primary care: a nested case–control study using the QResearch database by Aleksandar Radunović, Carol Coupland, Julia Hippisley-Cox, Christopher J McDermott, Tom A Ranger, Judith Burchardt, Xue W Mei

“…Additionally, the associations between MND diagnosis and family history, dropped foot, focal weakness and sialorrhoea remained robust after controlling for confounders. …”
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GENOME POLITICS: STRATEGY AND TACTICS by Jonas Rubikas

“…Evidence of that is the damage to mental functions in various disorders of genome. …”
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ELAVL1‐dependent SOAT2 exacerbated the pancreatitis‐like cellular injury of AR42J cells induced by hyperstimulation with caerulein by Yu‐Jing Sun, Hua‐Ying Chen, Xiao‐Qin Lai

“…Abstract Pancreatitis is a severe inflammatory condition characterized by damage to the pancreas. Sterol o‐acyltransferase 2 (SOAT2) has been reported to aggravate acute pancreatitis, however, the underlying mechanism remains to be elucidated. …”
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Implementasi QR Code Berbasis Android pada Sistem Presensi by Afif Priyambodo, Ledya Novamizanti, Koredianto Usman

“…The system was tested with black-box testing, detection distance testing, light-based detection testing, and stained and damaged student card testing. The presence system is able to detect QR-Code with a minimum distance of 3 cm and a maximum distance of 45 cm with an accuracy rate of 98% and an average computing time of 1.3 seconds. …”
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Markers of vascular autoregulation in primary open-angle glaucoma by N.E. Fomin, A.V. Kuroyedov

“…Ischemia and hypoxia of anterior and posterior eye segments as well as ischemic damage of other ocular tissues provide potential mechanism contributing to the increased VEGF expression in ocular tissues. …”
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Effect of Melatonin as an Antioxidant Drug to Reverse Hepatic Steatosis: Experimental Model by Blanca Martínez Soriano, Antonio Güemes, Guillermo Pola, Azucena Gonzalo, Pilar Palacios Gasós, Ana C. Navarro, Roberto Martínez-Beamonte, Jesús Osada, José J. García

“…We analyze the parameters of oxidative stress: malondialdehyde (MDA), 4-hydroxyalkenals (4-HDA), and carbonyls, degree of fat infiltration (analyzed by direct vision by a pathologist and by means of a computer program of image treatment), and serological parameters of lipid metabolism and hepatic damage. These parameters were analyzed in animals to which hepatic steatosis was induced by means of dietary modifications. …”
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Update on Pulmonary Toxicity Induced by New Breast Cancer Treatments by Belluzzi L, Martinelli G, Medici B, Farina A, Martinelli E, Canino F, Caggia F, Molinaro A, Barbolini M, Tamburrano F, Moscetti L, Piacentini F, Dominici M, Omarini C

“…Overall, the risk of pulmonary toxicity is quite low but in some cases lung damage can be fatal. We conducted an update including the available published data regarding the incidence, mechanisms of pathogenesis, clinical presentations, and treatment of lung toxicity induced by new anticancer drugs. …”
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Epitranscriptome profiles reveal participation of the RNA methyltransferase gene OsMTA1 in rice seed germination and salt stress response by Yingbo Li, Ming Yin, Juan Wang, Xiuqin Zhao, Jianlong Xu, Wensheng Wang, Binying Fu

“…Results The knockout of OsMTA1 resulted in a decreased level of m6A methylation and delayed seed germination, together with increased oxidative damage in the osmta1-1 mutant, especially under salt stress, indicating that OsMTA1 performs a crucial function in rice seed germination and salt stress response. …”
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Exploring the potential benefits of areca nut extract in animal production: a review by Zhuying Liu, Zhuying Liu, Xiaolong Wang, Lixin Wen, Lixin Wen

“…Its remarkable anti-inflammatory and antioxidant potential, along with its outstanding performance in antibacterial, antifungal, and antiviral activities, plays a crucial role in inhibiting various pathogens and protecting cells from oxidative damage. This review aims to comprehensively explore the biological activities of areca nut extract and delve into its practical application potential in enhancing animal production efficiency and promoting sustainable livestock development.The pervasive presence of antibiotic residues—including tetracyclines, sulfonamides, and quinolones—in agricultural products such as meat, milk, and eggs has raised significant concerns due to their extensive use in animal husbandry. …”
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Palmitic acid-induced cell death: impact of endoplasmic reticulum and oxidative stress, mitigated by L-citrulline by Md. Rezwanul Habib, Yukako Tokutake, Shinichi Yonekura

“…Additionally, we examined whether L-citrulline can protect against PA-induced damage of MAC-T cells. Methods MAC-T cells were treated with 4-phenyl butyric acid (4-PBA) or N-acetyl-L-cysteine (NAC) to inhibit PA-induced ER stress and oxidative stress, respectively. …”
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Review on the Injury and Repair Mechanism of Skeletal Muscle Contusions by LIN Jianping, WANG Hao, GUO Mingling, WANG Shizhong, CHEN Shaoqing

“…Ca²⁺ is blocked due to structural damage or functional decline of calcium pump after SMC, leading to calcium depletion in the endoplasmic reticulum (ER). …”
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Subcutaneous Pectoral Edema After Arthroscopic Labral Repair Despite Normal Irrigation Fluid Usage and Surgery Duration by İnci Hazal Ayas, Yağız Oğul Akcan, Miray Haspolat, Mehmet Ali Tokgöz, İlke Keser, Ulunay Kanatlı

“…ABSTRACT Objectives Edema after shoulder arthroscopic surgery poses concerns due to its potential complications such as compartment syndrome, nerve damage, and respiratory issues. This study aimed to investigate the acute accumulation of subcutaneous fluid after shoulder arthroscopy. …”
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Saussurea gossypiphora extracts reduce inflammation by reversing inflammatory cytokine levels in in-vitro and in-vivo by Kalyani Jatoth, Pawan Kumar Anoor, Ramesh Kande, Sandeepta Burgula

“…Rats treated with MESGD showed minimum side effects such as liver damage, hemoglobin, platelet and WBC count were increased when compared with animals treated with standard anti-inflammatory drug Indomethacin. …”
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