FSTL1 aggravates high glucose-induced oxidative stress and transdifferentiation in HK-2 cells by Baoyuan Zhang, Hang Geng, Kai Zhao, Moussa Omorou, Shuang Liu, Zhihui Ye, Fanting Zhang, Haiyan Luan, Xuesong Zhang

“…Silencing of FSTL1 ameliorates cellular damage by promoting proliferation, enhancing superoxide dismutase (SOD) and glutathione (GSH) activity, and reducing malondialdehyde (MDA) production, inhibiting cell migration. …”
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Local abnormal white matter microstructure in the spinothalamic tract in people with chronic neck and shoulder pain by Zhiqiang Qiu, Tianci Liu, Chengxi Zeng, Maojiang Yang, Xiaoxue Xu

“…Partial correlation analysis indicates that in people with CNSP, the FA values of the STT in regions with damaged white matter structure show a negative correlation with VAS scores and duration of pain, whereas MD values show a positive correlation with VAS scores and duration of pain.ConclusionThis study found that people with CNSP exhibit white matter microstructural abnormalities in the specific segments of STT. …”
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The effects of coenzyme q10 on testes of rats with diabetes induced by streptozotocin by Tuğba Özaydın, Yasemin Öznurlu, Emrah Sur

“…<p> <b>Conclusion: </b>In conclusion, CoQ₁₀ play a role in reducing the cellular damages caused by diabetes.…”
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A preliminary exploration of establishing a mice model of hypoxic training by Minglu Li, Zhijie Chen, Ziyang He, Xinjuan Zhang, Yanqiu Liu, Hui Zhou, Hang Yang, Tao Liu, Xiaochuan Wang, Ran Zhang, Jiaxing Zhang

“…Moreover, hypoxic training may alleviate the damage of hypoxia to the body.…”
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Factors Associated with Midterm Visual Field Variability in Patients with Stable Glaucoma by Maria Emília V. Guimarães, Carolina P. B. Gracitelli, Syril Dorairaj, Fábio N. Kanadani, Tiago S. Prata

“…Baseline data assessed were age, gender, educational level, intraocular pressure (IOP), central corneal thickness, best-corrected visual acuity, spherical equivalent, number of hypotensive eye drops, type of glaucoma, number of VFs performed, follow-up in years, lens status, visual field index (VFI) values from the last 5 VF (standard automated perimetry (SAP)) tests, the presence or absence of central scotoma in the VF test, and the level of glaucomatous damage according to the VF mean deviation (MD) index of the last VFs. …”
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REDD1 mediates HDM-induced nuclear-cytoplasmic translocation and release of IL-33 in airway epithelial cells by downregulating Nrf2 by Tian Luo, Wentao Ji, Yuxin Gong, Lichang Chen, Chao Liu, Dandan Zhang, Xi Li, Yanhua Lv

“…Abstract Objective This study aims to investigate whether REDD1 (Regulated in Development and DNA Damage Responses 1) mediates the nuclear-to-cytoplasmic translocation and release of IL-33 in airway epithelial cells induced by house dust mites (HDM). …”
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<i>Sambucus nigra</i>-Lyophilized Fruit Extract Attenuated Acute Redox–Homeostatic Imbalance via Mutagenic and Oxidative Stress Modulation in Mice Model on Gentamicin-Induced Nephr... by Kamelia Petkova-Parlapanska, Ivaylo Stefanov, Julian Ananiev, Tsvetelin Georgiev, Petya Hadzhibozheva, Veselina Petrova-Tacheva, Nikolay Kaloyanov, Ekaterina Georgieva, Galina Nikolova, Yanka Karamalakova

“…<b>Conclusions:</b> Histological evaluation confirmed that <i>S. nigra</i> (120 mg kg⁻¹) attenuated renal dysfunction and structural damage by modulating oxidative stress and acute inflammation and could be used as an anti-fibrotic alternative in GM nephrotoxicity.…”
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Environmental maternal exposures and the risk of premature birth and intrauterine growth restriction: The Generation Gemelli study protocol of newborn exposome. by Leonardo Villani, Angelo Maria Pezzullo, Roberta Pastorino, Alessandra Maio, Francesca Stollagli, Chiara Tirone, Marta Barba, Angela Maria Cozzolino, Denise Pires Marafon, Martina Porcelli, Annamaria Sbordone, Maria Letizia Patti, Anthea Bottoni, Angela Paladini, Simona Fattore, Domenico Marco Romeo, Ornella Parolini, Wanda Lattanzi, Guido Rindi, Luca Tamagnone, Marco Marazza, Maurizio Genuardi, Elisabetta Tabolacci, Eugenio Maria Mercuri, Antonio Chiaretti, Tina Pasciuto, Maurizio Sanguinetti, Vincenzo Valentini, Giovanni Scambia, Walter Ricciardi, Giovanni Vento, Antonio Lanzone, Stefania Boccia

“…We will perform laboratory examinations including dosage of heavy metals and essential elements, investigation of placental distress and fetal brain damage of biomarkers, analysis of microbiota and of DNA methylation profile. …”
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Proliferin-1 Ameliorates Cardiotoxin-Related Skeletal Muscle Repair in Mice by Hiroki Goto, Aiko Inoue, Limei Piao, Lina Hu, Zhe Huang, Xiangkun Meng, Yusuke Suzuki, Hiroyuki Umegaki, Masafumi Kuzuya, Xian Wu Cheng

“…PLF-1 blocking accelerated CTX-related muscle damage and dysfunction. In C2C12 myoblasts, rPLF-1 increased the levels of proteins for p-Akt, p-mTOR, p-GSK3α/β, p-Erk1/2, and p-p38MAPK as well as cellular functions; and these effects were diminished by the depletion of PLF-1 or silencing of its mannose-6-phosphate receptor. …”
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α-Bisabolol alleviates diesel exhaust particle-induced lung injury and mitochondrial dysfunction by regulating inflammatory, oxidative stress, and apoptotic biomarkers through the... by Sumaya Beegam, Nur Elena Zaaba, Ozaz Elzaki, Abderrahim Nemmar

“…Intratracheal instillation of DEPs induced DNA damage and increase in the apoptotic marker cleaved caspase-3. …”
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Radiation-assisted tailoring of swelling behavior and water retention of Na-CMC/PAAm hydrogels for enhancing Beta Vulgaris under drought stress by Mahmoud A. El-diehy, Ibrahim I. Farghal, Mohamed A. Amin, Mohamed Mohamady Ghobashy, Abdelatti I. Nowwar, H. M. Gayed

“…Surprisingly, the improved hydrogels retained more water: about 75% even after 16 days as opposed to a 50% drop within five days in the case of unmodified ones. …”
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Preparation and In Vitro Evaluation of Alginate Microparticles Containing Amphotericin B for the Treatment of Candida Infections by Merlis P. Alvarez-Berrios, Lisa M. Aponte-Reyes, Lourdes Diaz-Figueroa, Juan Vivero-Escoto, Alexis Johnston, David Sanchez-Rodriguez

“…However, it induces severe side effects such as nephrotoxicity, cardiac alterations, nausea, fever, and liver damage. The utilization of drug delivery systems has been explored to overcome these limitations. …”
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Lactococcus lactis D4 Decreases NF-κB and α-SMA in Rat Models of Obstructive Jaundice by Avit Suchitra, Alvarino Alvarino, Eryati Darwin, Harnavi Harun, Muhammad Iqbal Rivai, Ade Sukma

“…BACKGROUND: Obstructive jaundice, often due to choledocholithiasis or malignancies, leads to immune suppression, intestinal damage, and bacterial translocation, worsening outcomes. …”
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Stem solidness as an important factor for wheat protection from European wheat stem sawfly (<i>Cephus pygmaeus</i> L.) in Altai by S. B. Lepekhov, V. A. Petin, M. V. Chebatareva

“…Stem solidness significantly decreases the damage from wheat stem sawfly and has no negative effect on yield or gluten and protein content in grain. …”
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High Antennal Expression of <i>CYP6K1</i> and <i>CYP4V2</i> Participate in the Recognition of Alarm Pheromones by <i>Solenopsis invicta</i> Buren by Xinyi Jiang, Jiacheng Shen, Peng Lin, Youming Hou

“…Insects have highly developed olfactory systems in which cytochrome P450s (CYPs) were involved as odor-degrading enzymes throughout the olfactory recognition of odor compounds by insects to avoid continuous stimulation of signaling molecules and thus damage to the olfactory nervous. To understand whether the highly expressed CYPs in the antennae play an olfactory function in <i>Solenopsis invicta</i> worker, in this study, we find six highly expressed antennal CYPs from the transcriptome of <i>S. invicta</i>. …”
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Grounds and conditions for the application of preventive measures during the pre-trial investigation of corruption criminal offenses by V. V. Romaniuk, R. I. Login

“…The legal basis is the existence of a reasonable suspicion that a person has committed a corruption criminal offense and risks that give the investigating judge sufficient grounds to believe that the suspect may not fulfill the procedural duties assigned to him and try to hide from the pre-trial investigation bodies, commit actions to destroy or damage evidentiary information, illegally influence other participants in the criminal proceedings, or otherwise obstruct criminal proceedings, or continue criminal illegal activities. …”
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Investigation of the Prevalence of Infectious Myonecrosis Virus (IMNV) from 2022 to 2023 by Ruidong XU, Jitao XIA, Ping LI, Xingtong YU, Liang YAO, Wenqiang LI, Tianchang JIA, Qingli ZHANG

“…The characteristic coagulation necrosis of IMNV infection was found in the white muscle tissue sections of the ventral and caudal segments of the diseased shrimp, with a clear blue-violet hybridization signal of the IMNV probe in the muscle tissue with pathological damage. The results of this study indicated a high positive rate of IMNV in cultured shrimp, biological live bait, and offshore seawater in many Chinese provinces between 2022–2023. …”
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Gastric Cancer Cell Lines Have Different MYC-Regulated Expression Patterns but Share a Common Core of Altered Genes by Jersey Heitor da S. Maués, Helem Ferreira Ribeiro, Giovanny R. Pinto, Luana de Oliveira Lopes, Letícia M. Lamarão, Carla Mariana F. Pessoa, Caroline de Fátima Aquino Moreira-Nunes, Raimundo Miranda de Carvalho, Paulo P. Assumpção, Juan A. Rey, Rommel M. Rodríguez Burbano

“…We were able to detect 11 significant gene sets when comparing our samples to the hallmark collection of gene expression, enriched mostly for the following hallmarks: proliferation, pathway, signaling, metabolic, and DNA damage response. When we analyzed our DEGs considering KEGG metabolic pathways, we found 12 common branches covering a wide range of biological functions, and three of them were common to all three cell lines: ubiquitin-mediated proteolysis, ribosomes, and system and epithelial cell signaling in Helicobacter pylori infection. …”
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Improvement of Post‐Thaw Quality and In Vivo Fertility of Simmental Bull Spermatozoa Using Ferulic Acid by Mobin Afsar, Ali Soleimanzadeh, Amir Khaki, Esmail Ayen

“…It also increased GPx and TAC levels, reducing MDA and DNA damage after freezing. The addition of FA did not affect SOD values. …”
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Preterm nutrition and brain development by Chiara Nava, Gianluca Lista, Enrica Lupo

“…In particular through the gut-brain axis it seems that they can regulate the inflammatory response and oxidative stress, mechanisms responsible for neurological damage of preterm infants. Nevertheless, evidence is still lacking on this point. …”
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