IRG1/itaconate enhances efferocytosis by activating Nrf2-TIM4 signaling pathway to alleviate con A induced autoimmune liver injury by Liwu Zeng, Yaxin Wang, Yongzhou Huang, Wenchang Yang, Pei Zhou, Yaqi Wan, Kaixiong Tao, Ruidong Li

“…Efferocytosis is a vital mechanism for preventing the progression of inflammatory tissue damage. However, the mechanism by how IRG1/itaconate regulates efferocytosis in autoimmune hepatitis has yet to be fully understood. …”
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Long-Term Effect of Half-Fluence Photodynamic Therapy on Fundus Autofluorescence in Acute Central Serous Chorioretinopathy by Martin Stattin, Stefan Hagen, Daniel Ahmed, Eva Smretschnig, Florian Frommlet, Katharina Krepler, Siamak Ansari-Shahrezaei

“…After 7 years, normalized SW-FAF GV were significantly lower in eyes with resolved acute CSCR treated with reduced-fluence PDT compared to the follow-up after 1 month without correlation to explicit pattern changes or structural damages. Half-fluence PDT remains a safe and considerable treatment option in acute CSCR.…”
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The Soviet Factor in the US-China Military-Technical Cooperation during the Cold War by Yinan Li

“…The author shows that during this period Washington clearly subordinated the US-Chinese cooperation to the development of the US-Soviet relations out of fear to damage the fragile process of detente. The second section focuses on the evolution of the R. …”
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Analysis of strawberry genetic collection (Fragaria L.) for Rca2 and Rpfl genes with molecular markers by I. V. Luk’yanchuk, A. S. Lyzhin, I. I. Kozlova

“…Some of the common strawberry's diseases, causing significant damage to strawberry plantations, are anthracnose (Colletotrichum acutatum Simmonds) and red stele root rot (Phytophthora fragariae var. fragariae Hickman). …”
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Analyzing Tight Sand Characteristics and Its Influence on Aqueous Phase Removal by Gas Displacement by Mianmo Meng, Hongkui Ge, Yinghao Shen, Wenming Ji, Yang Wu, Xiaosong Xu, Weihan Huang, Qinyu Li, Jiayao Yu

“…Liquid filtration plays a main role in the formation damage. Flowback rate is closely related to the formation permeability recovery. …”
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Importance of benzoyltransferase GcnE and lysine benzoylation of alcohol dehydrogenase AdhB in pathogenesis and aflatoxin production in Aspergillus flavus by Xuan Chen, Lihan Wu, Yuqi Zhang, Sen Wang, Shihua Wang

“…Both adhB deletion mutant and benzoylated site mutants (K321R and K321A) exhibited similar phenotype, including decreased conidiation and seed colonization, increased sclerotia formation and aflatoxin production, and more sensitive to cell wall damage stress. We also found that GcnE has benzoyltransferase activity in vitro and in vivo, and its repression leads to decreased Kbz level and enzymatic activity of AdhB. …”
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Study on Strength and Permeability of Silt Soils Improving by Tung Oil and Sticky Rice Juice by Xiao-Wu Tang, Yue Yu, Li-Pei Zhou, Min-Liang Fei, Guo-Ping Sun

“…Tianluoshan site (5000∼2500 BC), which belongs to the Hemudu culture, has suffered damages from the hydraulic effect like other Chinese earthen sites in moist circumstance. …”
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The AMD-associated genetic polymorphism CFH Y402H confers vulnerability to Hydroquinone-induced stress in iPSC-RPE cells by Angela Armento, Inga Sonntag, Ana-Cristina Almansa-Garcia, Merve Sen, Sylvia Bolz, Blanca Arango-Gonzalez, Ellen Kilger, Ruchi Sharma, Kapil Bharti, Rosario Fernandez-Godino, Berta de la Cerda, Simon J. Clark, Simon J. Clark, Simon J. Clark, Marius Ueffing

“…RPE cells were treated with Hydroquinone (HQ), a component of cigarette smoke, to induce oxidative damage. ResultsIntriguingly, RPE cells carrying high genetic risk proved more vulnerable to oxidative insult when exposed to HQ, as demonstrated by increased cytotoxicity and caspase activation, compared to the low-risk RPE cells. …”
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Higher 3-year recurrence-free survival rate in patients with complete pathological remission following neoadjuvant chemotherapy plus immunotherapy for esophageal cancer: a two-cent... by Hai Zhang, Hai Zhang, Hai Zhang, Haiquan He, Qingyi Feng, Bomeng Wu, Ying Chen, Zhenyang Zhang, Linrong Zhou, Cui Li, Wanli Lin, Jiangbo Lin, Jiangbo Lin

“…No significant differences were observed in the incidences of hemoglobin decrease, platelet decrease, liver function damage, elevated serum creatinine, diarrhea, radioactive pneumonia or immunotherapy-related pneumonia, and esophageal perforation. …”
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Traumatic Blunt Force Renal Injury in a Diseased Horseshoe Kidney with Successful Embolization to Treat Active Bleeding: A Case Report and Literature Review by Chonlada Krutsri, Pongsasit Singhatas, Preeda Sumpritpradit, Chunlaches Chaijareenont, Wit Viseshsindh, Tharin Thampongsa, Pattawia Choikrua

“…Surgical reconstruction and preservation of a damaged horseshoe kidney is difficult because of variations in its vascular anatomy. …”
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Long-term Conservative Follow-up in Children with High-grade Vesicoureteral Reflux and an Abnormal Dimercaptosuccinic Acid Scan by Pankaj V Deshpande

“…Aim: High-grade vesicoureteral reflux (VUR) with an abnormal dimercaptosuccinic acid (DMSA) scan is considered to be a high risk for recurrent urine infections (UTIs) and advised surgery in most parts of India to prevent the high risk of UTIs and renal damage. In this retrospective study, we looked at 82 children with high-grade VUR and abnormal DMSA, having conservative follow-ups, to determine if they had recurrent UTIs and what their renal function and growth were at the end of follow-ups. …”
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Newly identified c-di-GMP pathway putative EAL domain gene STM0343 regulates stress resistance and virulence in Salmonella enterica serovar Typhimurium by Kaifeng Chen, Lili Li, Nanwei Wang, Zhouping Zhou, Peng Pan, Chenggang Xu, Dage Sun, Jiayi Li, Changzhi Dai, Dai Kuang, Ming Liao, Jianmin Zhang

“…In in vivo experiments, mice challenged with 269ΔSTM0343 experienced greater weight loss, and the bacterial loads in the spleen, liver, and intestines were elevated by fivefold, 30-fold, and 21-fold, respectively, accompanied by more severe pathological damage. Mechanistic studies revealed that the adhesion and invasion capacities of 269ΔSTM0343ΔCsgB decreased by 29.41% and 68.58%, respectively, compared to 269ΔSTM0343. …”
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The immunogenicity of PRV ΔgE/TK/UL49.5 three-gene-deleted vaccine in mice by Chenmeng Ding, Yawei Sun, Xianfeng Zhang, Mengmeng Shi, Han Yang, Xin Zhou, Shuangshuang Li, Yongtao Li, Xia Yang, Linyang Yu, Lu Chen

“…No obvious pathological damage was observed in lung, brain and trigeminal ganglion of mice immunized with PRV ΔgE/TK/UL49.5, and the tissue viral load was the lowest. …”
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The efficacy and safety of peroperative statin treatment during coronary artery bypass grafting by I.V. Shklianka, O.J. Zharinov, К.O. Mikhaliev, O.A. Yepanchintseva, B.M. Todurov

“…Cases of acute kidney damage were noted with the same frequency in groups two and three (by 10 %), in group three – were not registered. …”
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Winery By-Products In Vitro and In Vivo Effects on Atherothrombotic Markers: Focus on Platelet-Activating Factor by Maria Choleva, Smaragdi Antonopoulou, Elizabeth Fragopoulou

“…Evidence from long-term studies shows that consumption may lower total and low density lipoprotein (LDL) cholesterol, improve insulin sensitivity, decrease lipid and protein oxidative damage, enhance antioxidant capacity, and have mild anti-inflammatory action toward reducing cytokine expression and levels. …”
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A Morphometric Approach to Bozkurt (Kastamonu-Türkiye) Flood by Vedat Avci, Ömer Ünsal

“…Conservation and strengthening of natural vegetation in the study area will reduce the damage level of floods and overflows.…”
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The subventricular zone neurogenic niche provides adult born functional neurons to repair cortical brain injuries in response to diterpenoid therapy by Ricardo Pardillo-Díaz, Patricia Pérez-García, María Ortego-Domínguez, Ricardo Gómez-Oliva, Nora Martínez-Gómez, Samuel Domínguez-García, Francisco García-Cózar, Juan Pedro Muñoz-Miranda, Rosario Hernández-Galán, Livia Carrascal, Carmen Castro, Pedro Nunez-Abades

“…Neuregulin is expressed in microglial cells that reach the injury in response to the damage and its release is increased by EOF2 treatment. …”
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The relationship between C-reactive protein to lymphocyte ratio and the prevalence of chronic kidney disease in US adults: a cross-sectional study by Pengfei He, Jiao Zhang, Ni Tian, Yuanyuan Deng, Min Zhou, Cheng Tang, Yu Ma, Mianzhi Zhang, Mianzhi Zhang

“…The associations between CLR and CKD prevalence, as well as indicators of renal damage, were explored. Non-linear relationships were analyzed using weighted restricted cubic splines. …”
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The challenges of using Escherichia coli as a host in recombinant insulin production by Muhammad Taher

“… Diabetes mellitus is a metabolic disease characterised by elevation of blood glucose level which leads to serious damage to the blood vessels, eyes, heart, kidney, and nerves affecting about 830 million people worldwide. …”
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OMEGA-3 Fatty Acids Retention, Oxidative Quality, and Sensoric Acceptability of Spray-Dried Flaxseed Oil by Muhammad Zia Shahid, Muhammad Imran, Muhammad Kamran Khan, Muhammad Haseeb Ahmad, Muhammad Nadeem, Niaz Muhammad, Adeela Yasmin

“…Spray-drying is considered a processing technique to shield omega-3 fatty acids from oxidative damage. For the purpose, the extracted flaxseed oil (FSO) together with the emulsifier (flaxseed meal polysaccharide gum) was passed through a mini spray-dryer to prepare spray-dried flaxseed oil (SDFSO) samples. …”
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