Deep eutectic solvent enhances antibacterial activity of a modular lytic enzyme against Acinetobacter baumannii by Aleksandra Maria Kocot, Tomasz Swebocki, Karolina Ciemińska, Adrianna Łupkowska, Małgorzata Kapusta, Dennis Grimon, Ewa Laskowska, Anna-Karina Kaczorowska, Tadeusz Kaczorowski, Rabah Boukherroub, Yves Briers, Magdalena Plotka

“…Confocal fluorescence microscopy indicated that reline damaged the structure of the biofilm, allowing MLE-15 to penetrate it. …”
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Indicative features of tissue and microbial sensitization in the pathogenesis of generalized parodontitis associated with rheumatoid arthritis by A.M. Proschenko, N.S. Proschenko, L.L. Reshetnyk, N.A. Zelinskaya, N.V. Chervonna, Т.А. Melnychyk

“…Established sensitization to bone antigen in a small number of patients (27-33%) with GP, which was significantly more frequent (61-80%) in patients with GP associated  with RA, indicates that in the latter, allergy is to a greater extent due to tissue systemic damage to connective tissue than GP. However, a certain allergy to bone tissue in GP may indicate the inclusion of an immune component in the pathogenesis of GP. …”
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Effects of oral Lcarnitine supplementation on liver enzymes in pediatric acute lymphoblastic leukemia patients in the maintenance phase of treatment: a randomized clinical trial st... by Aziz Eghbali, Aygin Eghbali, Neda Ashayeri, Fatemeh Fadayi, Kazem Ghaffari, Kazem Ghaffari, Kazem Ghaffari, Ali Ghasemi, Ali Ghasemi

“…The incidence of side effects was significantly higher in the Lcarnitine group than in the placebo group (18% vs 4%, P = 0.025).ConclusionThe results of this study suggested that a 60-day Lcarnitine treatment can improve liver enzyme levels and thus prevent the extent of liver damage during the treatment of ALL. Based on the results of our study, Lcarnitine supplementation may have a beneficial effect on liver enzyme levels in pediatric ALL patients during the maintenance phase of treatment.Clinical Trial Registration:https://irct.behdasht.gov.ir/search/result?…”
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Antibacterial and antibiofilm activities of kaffir lime essential oils and their active constituents against Staphylococcus aureus focusing on sortase A by Chayapol Pontanayodsakorn, Chatchakorn Eurtivong, Pimsumon Jiamboonsri

“…Interestingly, terpinen-4-ol caused visible damage to the bacterial cell barrier, as revealed by SEM micrographs. …”
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The Effects of Cryogenic Process on the AISI M2 Punch Materials and on the Hole Edge Geometry of the DIN EN 10111-98 Sheet Metal Control Arm Parts by Yusuf Arslan

“…The hole edge geometries of the selected parts were measured with a contour measuring machine in the specified number of blanks. So, no damage was done to the products for measurements. …”
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Digital modeling of soil-borne fusarium’s nutritional: Investigating microbiological and microecological dynamics in Moroccan agroecosystems by El Hilali Alaoui Youssef, Bouda Said, Chabaa Samira, Elouali Alami Mohammed, Khoudi Zakaria, Essarioui Adil

“…Our research provides a foundation for modeling efforts aimed at generating forecasts to mitigate the damages caused by Bayoud on Morocco’s vital date palm ecosystems.…”
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Dynamic evaluation of vertebral alveolar echinococcosis using MR T2 mapping by Jinhuan Han, Yushan Chang, Hui Guo

“…Conclusion The MR T2 mapping technique can quantitatively evaluate the changes of vertebral alveolar echinococcosis, and it shows sensitivity to pathological changes in vertebrae prior to detectable damage using conventional MRI; this offers potential for early detection of vertebral alveolar echinococcosis.…”
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Registered Nurses' Experience of Person‐Centred Care Through Digital Aids in Primary Care Setting During the COVID‐19 Pandemic by Annika Kjällman Alm, Ove Hellzen, Malin Rising‐Holmström

“…However, they also voiced concerns that some patients, such as self‐damaging teenagers, new patients and multi‐sick patients, would be unsuitable for digital meetings. …”
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Evaluation of nutrient loads conveyed to the deep subalpine lakes of Northern Italy through their main tributaries by Paolo Dezuanni, Paolo Dezuanni, Diego Copetti, Claudia Dresti, Nicolò Pella, Nicolò Pella, Fabio Buzzi, Andrea Fenocchi, Andrea Fenocchi

“…Nutrient pollution is a critical issue for lakes, leading to cultural eutrophication, which damages the ecosystem and prevents water uses. Proper watershed management practices must be put into action to effectively oppose eutrophication. …”
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Experimental Study on Physicomechanical Properties of Deep Sandstone by Coupling of Dry-Wet Cycles and Acidic Environment by Xin Huang, Jianyong Pang, Guangcheng Liu, Yu Chen

“…Based on the analysis of the experimental phenomena, the constitutive model of uniaxial compression based on Weibull damage variable has been established in this article, and the model has the best effect in acid solution with less cycle times or pH value of solution greater than 6.…”
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Qizhu Rougan Granules suppress liver fibrosis by inhibiting the expression of the P2Y14 receptor on hepatic stellate cells by Yujing Tao, Yujing Tao, Qun Niu, Qun Niu, Yuanqian Yao, Yuanqian Yao, Kaixin Wang, Kaixin Wang, Haijian Dong, Haijian Dong, Xin Zhao, Xin Zhao, Zijian Zeng, Zijian Zeng, Hui Li

“…Liver morphology and fibrosis were evaluated using hematoxylin-eosin (H&E) and Masson’s trichrome staining, while gene and protein expression levels were analyzed through quantitative reverse transcription polymerase chain reaction (RT-PCR) and western blot techniques.ResultsThe results showed that QZRG granules significantly reduced serum levels of AST, ALT, and ALP in CCl4-treated mice, alleviated liver damage, and reduced collagen accumulation. …”
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CD73/adenosine dynamics in treatment-induced pneumonitis: balancing efficacy with risks of adverse events in combined radio-immunotherapies by Lena Gockeln, Florian Wirsdörfer, Verena Jendrossek

“…Furthermore, the CD73/adenosine pathway can also limit the immune-activating effects of cytotoxic therapies by degrading the pro-inflammatory danger molecule ATP, which is released into the tumor microenvironment and normal lung tissue upon therapy-induced cell damage. Thus, while targeting CD73 may enhance the efficacy of radio-immunotherapies in cancer treatment by mitigating tumor immune escape and improving immune-mediated tumor killing, it also raises concerns about increased immune-related adverse events (irAEs) in the normal tissue. …”
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Research progress of combined treatment of western medicine in children with allergic purpura (儿童过敏性紫癜西药联合治疗的研究进展) by HU Yuan (胡园), CHEN Xiuying (陈秀英), LIU Lili (刘莉莉)

“…Clinical manifestations include skin purpura, joint pain, abdominal pain and kidney damage. Severe or delayed treatment may lead to gastrointestinal bleeding, renal failure and even death. …”
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Effects of dietary Bacillus subtilis 14823 on growth performance, gut barrier integrity and inflammatory response of broilers raised in a stressful tropical environment by Sunisa Khongthong, Pipat Piewngam, Natthrit Roekngam, Prapot Maliwan, Sonsawan Kongpuckdee, Juthatip Jeenkeawpleam, Prawit Rodjan

“…HS impacts gut health by causing damaged mucosal microstructures, increased oxidative stress, weakened immunity, and heightened permeability to toxins and poultry pathogens. …”
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Targeted Polymer–Peptide Conjugates for E-Selectin Blockade in Renal Injury by Nenad Milošević, Marie Rütter, Yvonne Ventura, Valeria Feinshtein, Ayelet David

“…Background/Objectives: Leukocytes play a significant role in both acute kidney injury (AKI) and chronic kidney disease (CKD), contributing to pathogenesis and tissue damage. The process of leukocyte infiltration into the inflamed tissues is mediated by the interactions between the leukocytes and cell adhesion molecules (CAMs, i.e., E-selectin, P-selectin, and VCAM-1) present on the inner surface of the inflamed vasculature. …”
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Research on the Mechanism of Mannose Oligosaccharide Enhancing the Inhibitory Effect of Bifidobacterium breve on the Growth of Fusobacterium nucleatum by Xuyan ZHANG, Ruijie LIU, Bo ZHAO, Xiaoxi XU

“…The apparent structure was obviously damaged, protein and nucleic acid flowed out, and the integrity and permeability of the cell membrane were destroyed. …”
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Indicators of the Microbial Corrosion of Steel Induced by Sulfate-Reducing Bacteria Under the Influence of Certain Drugs by Nataliia Tkachuk, Liubov Zelena, Yaroslav Novikov

“…The prospect of further research is to assess the effect of DMSO and paracetamol on the indicators of microbial corrosion induced by SRB under the influence of the concentrations of these compounds found in wastewater, to clarify the possible additional causes of damage to the equipment of treatment plants. Further research should also be directed at investigating the antimicrobial properties of complexes of compounds with DMSO, which should be considered as an ecological solution to the problem of microbiologically influenced corrosion prevention.…”
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Comparison of an AI-based mobile pupillometry system and NPi-200 for pupillary light reflex and correlation with glaucoma-related markers by Damian Jaworski, Damian Jaworski, Karolina Suwała, Karolina Suwała, Bartlomiej J Kaluzny, Jakub J. Kaluzny, Jakub J. Kaluzny

“…Early detection is crucial for preventing irreversible damage. The pupillary light reflex (PLR) has proven useful in glaucoma diagnosis, and mobile technologies like the AI-based smartphone pupillometer (AI Pupillometer) offer a promising solution for accessible screening. …”
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Problems of Small and Medium Business in Germany by B. E. Zaritskiy

“…The key provisions of the government strategy to develop small and medium business adopted in 2019 and a cessionary package to mitigate damage of the coronavirus outbreak on the German economy adopted in 2020 are reviewed. …”
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Colonial legacy and traps in the social-ecological systems of forest management by C.D.A. Depari

“…In Mount Merapi, this maladaptation is manifested through the long-tailed macaque’s invasion of farmlands, triggered by the state’s failure to reforest the targeted 480 ha of damaged land after the 2010 eruption. This study aims to qualitatively interrogate factors that are hindering the swift restoration of Mount Merapi's social-ecological systems. …”
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