Aging Alters Olfactory Bulb Network Oscillations and Connectivity: Relevance for Aging-Related Neurodegeneration Studies by A. Ahnaou, D. Rodriguez-Manrique, S. Embrechts, R. Biermans, N. V. Manyakov, S. A. Youssef, W. H. I. M. Drinkenburg

“…The OB of aged mice showed a significant increase in the number of histone H2AX-positive neurons, a marker of DNA damage. While the input-output relationship measure of basal synaptic activity was found not to differ between young and aged mice, a pronounced decline in the slope of field excitatory postsynaptic potential (fEPSP) and the population spike amplitude (PSA) were found in aged mice. …”
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Preventive Effects of Intrauterine Injection of Bone Marrow-Derived Mesenchymal Stromal Cell-Conditioned Media on Uterine Fibrosis Immediately after Endometrial Curettage in Rabbit by Sanaz Bazoobandi, Nader Tanideh, Farhad Rahmanifar, Shahrokh Zare, Omid Koohi-Hosseinabadi, Iman Razeghian-Jahromi, Mehdi Dianatpour, Masoumeh Ahmadi, Arezoo Khoradmehr, Iraj Nabipour, Zahra Khodabandeh, Amin Tamadon

“…MSC-conditioned media (MSC-CM) contain paracrine components—exosomes—with a great potential for repairing damaged tissue or preventing fibrosis. The main goal of this study was to evaluate the preventive effects of bone marrow-derived MSC-CM (BM-MSC-CM) on uterine fibrosis after uterine curettage in rabbits. …”
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Study on Roof-Coal Caving Characteristics with Complicated Structure by Fully Mechanized Caving Mining by Yunpei Liang, Lei Li, Xuelong Li, Kequan Wang, Jinhua Chen, Zhongguang Sun, Xuelin Yang

“…Furthermore, the range of the plastic zone of the top coal and the damage degree of the top coal increase with the increase of mining depth. …”
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The Importance of Platelet-Derived Growth Factors as Markers of Survival and Severity of COVID-19 in Patients Undergoing Monthly Follow-Up by Elżbieta Cecerska-Heryć, Dominika Nieszpór, Natalia Serwin, Ewa Pius Sadowska, Marta Gliźniewicz, Bartłomiej Grygorcewicz, Karol Serwin, Anna Michalczyk, Marta Budkowska, Małgorzata Goszka, Aleksandra Polikowska, Radosław Birger, Bogusław Machaliński, Barbara Dołęgowska

“…Platelets are the first to reach the site of tissue damage and secrete substances like platelet growth factors (GFs), which perform many different functions in the human body. …”
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The potential role of differentially expressed tRNA-derived fragments in high glucose-induced podocytes by Zhenxing Zhang, Yunyang Qiao, Jialing Ji, Chan Huang, Huimin Shi, Weihua Gan, Aiqing Zhang

“…The prevalence of diabetic kidney disease (DKD) is increasing annually. Damage to and loss of podocytes occur early in DKD. tRNA-derived fragments (tRFs), originating from tRNA precursors or mature tRNAs, are associated with various illnesses. …”
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Investigating the Relationship between Socioeconomic Status and Traffic Behaviors of Pedestrians in Marand by Sepideh Harzand-Jadidi, Abolfazl Rahimi Bonab, Morteza Haghighi, Mohammad Saadati, Saeid Mousavi

“…Considering the high number of pedestrian accidents in Marand and their subsequent physical, psychological, social, and economic damages on the individual, family, and society, the current study was conducted to investigate the relationship between the socioeconomic status and traffic behavior of pedestrians. …”
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Biomarker Profiling for Pyridoxine Dependent Epilepsy in Dried Blood Spots by HILIC-ESI-MS by Elizabeth Mary Mathew, Sudheer Moorkoth, Leslie Lewis, Pragna Rao

“…If identified earlier and treated prophylactically with pyridoxine, severe brain damage due to seizures can be prevented. Alpha-amino adipic semialdehyde (AASA), piperidine-6-carboxylic acid (P6C), and pipecolic acid (PA) are known biomarkers of pyridoxine dependent epilepsy. …”
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Knockdown of PDPN in astrocytes reduces hippocampal inflammation in T2DM mice by Xiaohang Wang, Xiaohang Wang, Xiaohang Wang, Qianqian Wang, Zhensheng Cai, Chengming Ni, Huan Wang, Hui Liu, Yusong Zhao, Jinbang Wang, Subo Liu, Xueying Wang

“…These activated cells produce proinflammatory mediators like cytokines or chemokines, that cause cerebrovascular damage. Previous sequencing showed Pdpn’s high expression in activated stellate cells and possible inflammation involvement. …”
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TNBC response to paclitaxel phenocopies interferon response which reveals cell cycle-associated resistance mechanisms by Nicholas L. Calistri, Tiera A. Liby, Zhi Hu, Hongmei Zhang, Mark A. Dane, Sean M. Gross, Laura M. Heiser

“…We found that escalating doses of paclitaxel resulted in multinucleation, promotion of senescence, and initiation of DNA damage induced apoptosis. Single-cell RNA sequencing (scRNA-seq) of TNBC cells after paclitaxel treatment revealed upregulation of innate immune programs canonically associated with interferon response and downregulation of cell cycle progression programs. …”
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A20 as a Potential Therapeutic Target for COVID‐19 by Yongyao Wu, Lilan He, Rong Li, Jiuxuan Li, Qing Zhao, Bin Shao

“…It effectively suppresses the immune damage and inflammatory storm caused by viral infection. …”
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Modulation of Cognition: The Role of Gnidia glauca on Spatial Learning and Memory Retention in High-Fat Diet-Induced Obese Rats by Wycliffe Makori Arika, Cromwell Mwiti Kibiti, Joan Murugi Njagi, Mathew Piero Ngugi

“…The positive influences on cognitive functions might be attributed to the extracts’ phytochemicals that have been suggested to confer protection against obesity-induced oxidative damage, reduction of central inflammation, and increased neurogenesis. …”
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Relationship between Brittleness Index and Crack Initiation Stress Ratio for Different Rock Types by Juyu Jiang, Dong Wang, Xinping Han, Shuai Di

“…The crack initiation stress ratio (K) is defined as the ratio of σci to crack damage stress. The relationship between brittleness index and K is obtained from laboratory mechanics tests including uniaxial compression and Brazilian splitting tests. …”
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Curcumin and α/β-Adrenergic Antagonists Cotreatment Reverse Liver Cirrhosis in Hamsters: Participation of Nrf-2 and NF-κB by José Roberto Macías-Pérez, Bruno Jesús Vázquez-López, Martin Humberto Muñoz-Ortega, Liseth Rubí Aldaba-Muruato, Sandra Luz Martínez-Hernández, Esperanza Sánchez-Alemán, Javier Ventura-Juárez

“…Therefore, these results suggest for the first time that α/β adrenergic blockers with curcumin completely reverse hepatic damage, possibly as a result of adrenergic antagonism on HSC and conceivably by the increase of Nrf-2/NF-κB mRNA ratio.…”
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The In Vitro Antioxidant and Antiadipogenic Properties of Pigmented Flower Extracts of Geraniaceae and Lamiaceae Plant Families by Anton Venter, Hennie Fisher, Gary I. Stafford, June C. Serem, Megan J. Bester, Kwaku G. Duodu

“…These extracts protected Caco-2 cells against 2, 2′-azobis (2-amidinopropane) dihydrochloride (AAPH) generated oxidative damage. Similarly, all extracts, except P. zonale hybrid, effectively scavenged nitric oxide (NO) and reduced lipopolysaccharide (LPS)-induced NO formation in RAW 264.7 macrophages. …”
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Astrovirus infection in animals (literature review) by V. A. Mischenko, A. V. Mischenko, Т. B. Nikeshina, О. N. Petrova

“…Early postnatal diarrhea as the main reason of morbidity and mortality in young animals leads to serious problems in the commercial livestock farming and causes a considerable economic damage. The most common viral gastroenteritis agents in calves are rotaviruses, coronaviruses and pestiviruses, and, along with these, astroviruses are increasingly being detected. …”
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Effects of adipose allograft matrix on viability of humeral head cartilage and rotator cuff tendon by Andrea Karen Persons, Michael R. Baria, Ryan Rauck, Tyler Barker, Zarah Belacic, Sunjit Neginhal, Sushmitha Durgam

“…Adipose allograft matrix (AAM), which recruits native cells to damaged tissues, may also be a potential treatment for rotator cuff tears. …”
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Effect of glyphosate on renal function: A study integrating epidemiological and experimental evidence by Lin Hu, Mingcong Chen, Xiaoran Xue, Mingyi Zhao, Qingnan He

“…Glyphosate exposure is negatively associated with renal function in community adults. The damage to the kidneys caused by glyphosate may be mediated through the regulation of metabolic pathways, and the specific mechanisms require further experimental investigation.…”
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Tear matrix metalloproteinases-9 and ocular surface parameters in diabetics: a cross-sectional study in Shenyang, China by Ling Yang, Wei He, Jiayan Chen, Guanghao Qin, Emmanuel Eric Pazo, Zhengpeng Qu

“…Background Overexpression of tear matrix metalloproteinases-9 (MMP-9) on the ocular surface tissues has been reported to result in ocular surface damage. MMP-9 levels in tears have been listed as one of many tools for confirming dry eye disease (DED).Objective This investigation aimed to compare MMP-9 levels and ocular surface parameters in diabetic patients with and without DED.Design A cross-sectional study.Setting He Eye Specialist Hospital, Shenyang, China.Participants This study recruited 144 right eyes of 144 diabetic patients between November and December of 2023, and 110 patients with similar propensity scores were included in the analyses.Main outcome measures Non-invasive breakup time (NITBUT), tear film lipid layer (TFLL), conjunctival hyperaemia (redness score (RS)), corneoconjunctival staining (CS), corneal sensitivity and Ocular Surface Disease Index (OSDI) questionnaire were evaluated. …”
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Carpolobia lutea methanol root extract reinstates androgenesis and testicular function in cadmium- challenged rats by Ejike, Daniel Eze, Okpa, Precious Nwaka, Igbokwe, Ugochukwu Vincent, Moses, Dele Adams, Karimah, Mohammed Rabiu, Ayikobua, Emmanuel Tiyo

“…The study suggests that Carpolobia lutea extract plays a protective function in ameliorating testicular damage caused by cadmium in rats. This is probably due to the extract’s potential in the management of testicular dysfunction and fecundity in animals.…”
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Carpolobia lutea methanol root extract reinstates androgenesis and testicular function in cadmiumchallenged rats by Ejike, Daniel Eze, Precious Nwaka, Okpa, Ugochukwu Vincent, Igbokwe, Moses, Dele Adams, Mohammed Rabiu, Karimah, Emmanuel Tiyo, Ayikobua

“…The study suggests that Carpolobia lutea extract plays a protective function in ameliorating testicular damage caused by cadmium in rats. This is probably due to the extract’s potential in the management of testicular dysfunction and fecundity in animals.…”
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