Injuries from blank cartridge shots in suicide attempts within the South Korean military: a case series of five patients by Jeong Il Joo, Changsin Lee, Kyungwon Lee

“…Although initial vital signs and laboratory findings were unremarkable, computed tomography scans revealed injuries from projectile gas and gunpowder, including burns, subcutaneous emphysema, and major structural damage. Cases 1 and 2 required emergency surgery for foreign body removal and debridement. …”
Get full text

AOZORA: long-term safety and joint health in paediatric persons with haemophilia A without factor VIII inhibitors receiving emicizumab – protocol for a multicentre, open-label, pha... by Seitaro Yoshida, Masashi Taki, Hideyuki Takedani, Midori Shima, Keiji Nogami, Azusa Nagao, Haruko Yamaguchi-Suita, Yui Kyogoku, Akira Ishiguro, Kaoru Kitsukawa

“…Introduction Persons with haemophilia A (PwHA) commonly experience regular bleeding into joints, which may result in joint damage and complications such as degenerative arthritis. …”
Get full text

Effect of botanical powders and the assassin bug, Alloeocranum biannulipes Mont. and Sign. (Hemiptera: Reduviidae) against Dinoderus porcellus Lesne (Coleoptera: Bostrichidae) infe... by Kitherian SAHAYARAJ, Antonio SINZOGAN, Manuele TAMO, Joelle TOFFA, Yêyinou Laura Estelle LOKO, Armand VODOUNNON, Innocent DJEGBE

“…While, the dynamic population of D. porcellus, their damage, and weight loss of yam chips were recorded 8 weeks after treatment under farm conditions. …”
Get full text

A Simple Approach for Mitigating a New Flooding Attack in RPL-Based IoT Networks by Mehdi Rouissat, Ibrahim S. Alsukayti, Mohammed Belkheir, Mohammed Alreshoodi, Allel Mokaddem, Djamila Ziani

“…This paper introduces a new variant of the flooding attack namely the Destination Advertisement Object Flooding (DAOF) attack. It is based on using routing communications, particularly the DAO messages, to disseminate unnecessary routing traffic which instigate excessive transmissions of control messages across the network. …”
Get full text

Integrating network pharmacology and experimental validation to explore the pharmacological mechanism of Astragaloside IV in alleviating urotensin II-mediated renal tubular epithel... by Wenyuan Liu, Qianwei Liu, Ziyuan Zhang, Yaling Hu, Jingai Fang

“…In conclusion, AS-IV may improve UII-mediated renal tubular epithelial cell damage by down-regulating the cAMP/PKA signaling pathway.…”
Get full text

Design and fabrication of a device for cleaning greenhouse roofs by Ahmed Amin, Xiaochan Wang, Zhao Lianyuan, Yinyan Shi, Ren Xiaoyan, Mahmoud Okasha, Reda Hassanien Emam Hassanien

“…Moreover, the traditional way of cleaning greenhouse roofs using ladders is laborious and time-consuming, requires a lot of water, and puts too much pressure on the roof. It could cause damage and risky labor. Consequently, many farmers leave greenhouse roofs dirty, which decreases plant photosynthesis due to the low light intensity. …”
Get full text

Molecularly Distinct NLRP3 Inducers Mediate Diverse Ratios of Interleukin-1β and Interleukin-18 from Human Monocytes by Kristine Midtbö, Daniel Eklund, Eva Särndahl, Alexander Persson

“…IL-1β is an important mediator of the acute phase response to infections and tissue damage, whereas IL-18 takes part in activation and tailoring of the adaptive immune response. …”
Get full text

Harnessing genomic and bioinformatic data to broaden understanding of leukaemia across continents by Gumelar Gugun, Ulfa Mia Maria, Amukti Danang Prasetyaning, Irham Lalu Muhammad, Yuliani Sapto, Adikusuma Wirawan, Khairi Sabiah, Darmawi Darmawi, Chong Rockie, Ates Ilker, Singh Dilpreet, Chavan Aditya Ashok

“…The data was then screened using SNPnexus to detect potentially protein-damaging variants. Furthermore, the gene expression of these variants was analysed using the GTEx portal. …”
Get full text

Management of patients with dry eye syndrome with systemic autoimmune and infectious diseases by G.M. Chernakova, E.A. Kleshcheva

“…Fyodorov Eye Microsurgery Federal State Institution, Moscow<br> ² Russian Medical Academy of Continuous Professional Education, Moscow<br> <br> It is known, that instability and hyperosmolarity of the tear film, inflammation and damage to the eye surface play a leading role in the pathogenesis of dry eye syndrome (DES), as well as neurosensory disorders. …”
Get full text

Promising source material for winter triticale breeding under the conditions of the Middle Urals by G. N. Potapova, N. L. Zobnina, A. V. Bezgodov, M. S. Ivanova

“…‘Privada’, ‘Tsekad 90’ and ‘Nemchinovsky 58’ combined high winter hardiness (70–81%) with resistance to damage by snow mold (15–20%), high density of productive stems (324–425 pcs/m2), and high yield (562–616 g/m2). …”
Get full text

Low-dose radiation ameliorates PM2.5-induced lung injury through non-canonical TLR1/TLR2-like receptor pathways modulated by Akkermansia muciniphila by Li Wang, Zhipeng Li, Huan He, Lijing Qin, Weiqiang Xu, Hongyuan Tian, Rongrong Liu, Xinru Lian, Wen Li, Yali Qi, Zhicheng Wang

“…We observed that LDR ameliorated the lung damage induced by PM2.5 in mice. Additionally, after PM2.5 exposure, M1 polarization of macrophages in alveolar lavage fluid and Th1 polarization in spleen increased, pro-inflammatory cytokines (IL-1, IL-6 and TNF-α) increased and anti-inflammatory cytokines (IL-4, IL-10 and TGF-β) decreased in lung and serum. …”
Get full text

Vascular Pathology in Alpha 1 Antitrypsin Deficient Chronic Obstructive Pulmonary Disease and Emphysema Patients: Case Reports by Gordon M, Gangemi AJ, Sandwith EL, Kumaran M, Kueppers F

“…Early AATD diagnosis is crucial to prevent progressive lung damage and associated pathologies. Here, we present case reports of two patients with AATD from the Temple University Hospital Outpatient Clinic, who exhibited aneurysms of the aorta and splenic artery. …”
Get full text

Enucleated bone marrow-derived mesenchymal stromal cells regulate immune microenvironment and promote testosterone production through efferocytosis by Lu Sun, Jiayu Huang, Xuezi Wang, Peng Huang, Baolin Dong, Zehang Liang, Jiahong Wu, Jiancheng Wang

“…Conclusions In summary, this study pioneered the application of stromal cell enucleation technology to repair tissue damage in the reproductive system, explored the potential of cell burial in the treatment of reproductive system diseases and provided a new approach for the clinical treatment of male infertility.…”
Get full text

Injected Human Muscle Precursor Cells Overexpressing PGC-1α Enhance Functional Muscle Regeneration after Trauma by Deana Haralampieva, Souzan Salemi, Thomas Betzel, Ivana Dinulovic, Stefanie D. Krämer, Roger Schibli, Tullio Sulser, Christoph Handschin, Simon M. Ametamey, Daniel Eberli

“…While many groups demonstrated new muscle tissue formation after muscle precursor cell (MPC) injection, the capacity of these cells to heal muscle damage, for example, sphincter in stress urinary incontinence, in long-term is still limited. …”
Get full text

Cardiorenal Involvement in Metabolic Syndrome Induced by Cola Drinking in Rats: Proinflammatory Cytokines and Impaired Antioxidative Protection by Matilde Otero-Losada, Hernán Gómez Llambí, Graciela Ottaviano, Gabriel Cao, Angélica Müller, Francisco Azzato, Giuseppe Ambrosio, José Milei

“…Chronic cola drinking induced cardiac remodeling associated with increase in proinflammatory cytokines and renal damage. Hypertriglyceridemia and oxidative stress were key factors. …”
Get full text

Barium Sulfate Scale Removal at Low-Temperature by Hany Gamal, Saad Al-Afnan, Salaheldin Elkatatny, Mohamed Bahgat

“…Injecting the developed dissolver for damaged sandstone core sample with barite mud by flooding test showed a return permeability of 115%.…”
Get full text

Humoral and Cellular Immune Regulation in Albino Rat Exposed to Glyphosate and Aluminum Phosphide by Ujuamala Ezeani, Onyemaechi Afonne, Michael Ezeani

“…The chronic effects of these cytotoxic actions could potentially lead to tissue damage or trauma, resulting in subsequent chronic inflammation.…”
Get full text

Impact of quality of life on overall work productivity impairment and activity impairment of patients with systemic lupus erythematosus: the PEONY study by Yoshiya Tanaka, Shintaro Hirata, Shingo Nakayamada, Yusuke Miyazaki, Kazuyoshi Saito, Kunihiro Yamaoka, Shigeru Iwata, Yoshiyuki Yamaguchi, Keisuke Nakatsuka, Shunpei Kosaka, Katsuhide Kusaka, Toshiki Yabe-Wada, Masakazu Fujiwara, Yoshifumi Arita, Mitsuru Hoshino, Naoko Ozaki

“…Disease activity and organ damage were investigator-assessed. The primary objective was to assess the residual burden in patients in LLDAS and to investigate the association of LupusPRO domains with activity impairment using multivariate regression analysis. …”
Get full text

Safety and efficacy of omaveloxolone v/s placebo for the treatment of Friedreich's ataxia in patients aged more than 16 years: a systematic review by Ankita Umrao, Monika Pahuja, Nabendu Sekhar Chatterjee

“…Abstract Background Friedreich’s ataxia (FA) is a rare genetic disorder caused by silencing of the frataxin gene (FXN), which leads to multiorgan damage. Nrf2 is a regulator of FXN, which is a modulator of oxidative stress in animals and humans. …”
Get full text

Rectal application of a highly osmolar personal lubricant in a macaque model induces acute cytotoxicity but does not increase risk of SHIV infection. by Sundaram A Vishwanathan, Monica R Morris, Richard J Wolitski, Wei Luo, Charles E Rose, Dianna M Blau, Theodros Tsegaye, Sherif R Zaki, David A Garber, Leecresia T Jenkins, Tara C Henning, Dorothy L Patton, R Michael Hendry, Janet M McNicholl, Ellen N Kersh

“…Some water-based products with high osmolality and low pH can damage genital and rectal tissues, and the polymer polyquaternium 15 (PQ15) can enhance HIV replication in vitro. …”
Get full text