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16321
Explainable Machine Learning for Efficient Diabetes Prediction Using Hyperparameter Tuning, SHAP Analysis, Partial Dependency, and LIME
Published 2025-01-01“…ABSTRACT Diabetes is a chronic metabolic disease characterized by elevated blood glucose levels and poses significant health risks, such as cardiovascular disease and cognitive damage. Understanding the causes of diabetes is crucial to managing it and preventing complications. …”
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16322
Functional Evaluation of the Visual Pathway in Patients with Multiple Sclerosis Using a Multifunction Stimulator Monitor
Published 2019-01-01“…This device may be a fast and useful tool to provide a full evaluation of axonal damage in patients with multiple sclerosis.…”
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16323
A CD36-based prediction model for sepsis-induced myocardial injury
Published 2025-04-01“…Plasma CD36 levels were measured within 48 h of ICU admission, prior to the diagnosis of sepsis-associated myocardial injury. Myocardial damage was assessed using troponin levels. Results: Two significant risk factors for SIMI were identified: age and elevated CD36 levels. …”
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16324
Preparation, structural property, and antioxidant activities of a novel pectin polysaccharide from the flowers of Hibiscus syriacus Linn.
Published 2025-01-01“…Furthermore, HFPS effectively protected HepG2 cells against H2O2-induced oxidative stress by reducing ROS accumulation, modulating redox-related enzymes (Superoxide dismutase, Catalase, Glutathione peroxidase), and alleviating oxidative damage. Notably, HFPS upregulated the expression of antioxidant-related genes, including B-cell lymphoma-2 (Bcl-2), heme oxygenase 1 (HO-1), NAD(P)H quinone oxidoreductase 1 (NQO1), and nuclear factor erythroid 2-related factor 2 (Nrf2), while downregulating pro-apoptotic genes like Bcl-2-associated X protein (Bax) and Caspase-3. …”
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16325
Acute and Subchronic Airway Inflammation after Intratracheal Instillation of Quartz and Titanium Dioxide Agglomerates in Mice
Published 2011-01-01“…Differences were seen between the different polymorphs of nano-size TiO2, with rutile being the most inflammogenic and amorphous being the most potent in regard to acute tissue damage.…”
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16326
Application of Multimedia Quality Evaluation Relying on Intelligent Robot Numerical Control Technology in New Energy Power Generation System
Published 2023-01-01“…However, restricted by climate and other factors, the instability of its power generation capacity has a serious impact on the voltage multimedia quality evaluation of small microgrids, which even causes damage to important equipment. This paper proposed a multimedia quality evaluation method in the new energy power generation system relying on intelligent robot numerical control technology. …”
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16327
Higher detectability of amyloid with phenol Congo red compared with alkaline Congo red
Published 2024-11-01“…Introduction Amyloidosis is a heterogeneous group of conditions associated with tissue deposition of insoluble abnormal proteins that damage vital organs. Early diagnosis, when the deposits are minimal, determines the prognosis and requires histological confirmation. …”
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16328
Explosive Performance Assessment of Buried Steel Pipeline
Published 2021-01-01“…Explosion can generate much damage with vibration in vast soil media. Thus, it is important to predict the dynamic impact load and its treatment response. …”
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16329
Determination of the effect of danofloxacin on 8-hydroxy-2-deoxyguanosine level
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16330
The Protective Effect of Teprenone on Aspirin-Related Gastric Mucosal Injuries
Published 2019-01-01“…Long-term use of low-dose aspirin causes varying degrees of gastric mucosal damages and gastrointestinal symptoms; the severity will increase within a certain range with the extension of medication duration. …”
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16331
Activation of PTGS2/NF‐κB signaling pathway enhances radiation resistance of glioma
Published 2019-03-01“…In addition, PTGS2 activated NF‐κB signaling pathway and prevented DNA damage after radiotherapy. Lastly, PTGS2 was proved to facilitate tumor cell proliferation and improve the radio‐tolerance. …”
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16332
Potential Antioxidant Activity of New Tetracyclic and Pentacyclic Nonlinear Phenothiazine Derivatives
Published 2016-01-01“…The malondialdehyde level in groups 1 and 2 animals was lower than that in group 3 that received the reference compound (ascorbic acid) and group 4 that received the solvent suggesting the ability of the phenothiazine derivatives to prevent lipid membrane damage. AST and bilirubin levels were higher in group 2 animals which received 6-[4-bromophenyl]-10-methyl-11-azabenzo[a]phenothiazine-5-one compared to group 3, the positive control. …”
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16333
The AMPK–mTOR Pathway Is Inhibited by Chaihu Shugan Powder, Which Relieves Nonalcoholic Steatohepatitis by Suppressing Autophagic Ferroptosis
Published 2024-01-01“…Nonalcoholic steatohepatitis (NASH) is the advanced stage of nonalcoholic fatty liver disease (NAFLD), which is distinguished by the accumulation of fat in the liver, damage to liver cells, and inflammation. Chaihu Shugan powder (CSP), a renowned traditional Chinese medicine (TCM) blend extensively utilized in China to address liver disease, has demonstrated its efficacy in reducing lipid buildup and effectively combating inflammation. …”
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16334
Performance Comparison of Different Neuroimaging Methods for Predicting Upper Limb Motor Outcomes in Patients after Stroke
Published 2022-01-01“…CST‐wLL≥2.068 cc indicated serious CST damage and a poor outcome (100%). CST‐wLL<1.799 cc was correlated with a considerable rate (>70%) of upper limb motor function recovery. …”
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16335
Criminal law characteristics of mass destruction weapons as a criminal offense constructive objective feature (Articles 439, 440 of the Criminal Code of Ukraine)
Published 2022-06-01“…Its properties are always used by the criminal directly when committing the crime to cause or threaten to cause significant damage to the object of criminal law protection. As part of the criminal offense provided for in Art. 439 of the Criminal Code of Ukraine, weapons of mass destruction are the means of committing this crime.…”
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16336
Effect of Rho-Kinase and Autophagy on Remote Ischemic Conditioning-Induced Cardioprotection in Rat Myocardial Ischemia/Reperfusion Injury Model
Published 2022-01-01“…Compared with the sham group, the mean arterial pressure and heart rate were decreased, myocardial enzyme levels were increased, and myocardial damage was aggravated in the I/R group; however, RIC improved these alterations. …”
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16337
Therapeutic potential of phytocompounds of Bacopa monnieri (L.) Wettst (literature review)
Published 2024-10-01“…An analysis of clinical studies in Ukraine shows that drugs based on B. monnieri can be used in the complex treatment of cognitive impairment associated with dyscirculatory encephalopathy in adults and perinatal CNS damage in children. Considering the amphiphilicity of bacosides and the non-toxicity of extracts, they can be involved in the development of various dosage forms with a wide range of therapeutic applications. …”
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16338
Newly identified single-nucleotide polymorphism associated with the transition from nonalcoholic fatty liver disease to liver fibrosis: results from a nested case-control study in...
Published 2025-12-01“…Oxidative stress markers like elevated malondialdehyde (MDA) and reduced catalase (CAT) and superoxide dismutase (SOD) levels indicated liver damage in the TGF-β group. SAMM50-rs2073080 was upregulated in the NAFLD-associated fibrosis model. …”
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16339
Recurrent Multivalvular Staphylococcus Lugdunensis Endocarditis Causing Complete Heart Block after TAVR
Published 2021-01-01“…Staphylococcus lugdunensis is an unusual but virulent organism that may damage both native and prosthetic valves. Early surgery is recommended for PVE after TAVR, especially in cases with perivalvular disease causing conduction abnormalities. …”
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16340
Why do people walk their dog where the wild things are? A qualitative content analysis from an urban nature reserve
Published 2025-01-01“…Abstract Domestic dogs can have devastating impacts on threatened wildlife, but limiting their damage is challenging because it relies on changing the behaviour of people who bring dogs into natural areas and allow them to romp unrestrained. …”
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