Pressure Analysis for Volume Fracturing Vertical Well considering Low-Velocity Non-Darcy Flow and Stress Sensitivity by Zhongwei Wu, Chuanzhi Cui, Japan Trivedi, Ning Ai, Wenhao Tang

“…In general, there is stress sensitivity damage in tight reservoirs and fractures. Furthermore, the flow in tight reservoirs is the low-velocity non-Darcy flow. …”
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In Vitro and in Vivo Hypolipidemic Effects of Protein-Polysaccharide Complexes from Three Species of Edible Fungi by GAO Chen, LI Wen, CHEN Wanchao, WU Di, ZHANG Zhong, LIU Peng, XIA Yongjun, YANG Yan

“…In addition, the protein-polysaccharide complexes alleviated liver function damage caused by long-term high-fat diet. In summary, it can be concluded that A. bisporus, S. rugosa and M. esculenta protein-polysaccharide complexes can regulate lipid metabolism, alleviate liver injury and hyperlipidemia, which provides a reference for the development of functional products based on edible fungi.…”
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Differential Expression of IFN-γ, IL-10, TLR1, and TLR2 and Their Potential Effects on Downgrading Leprosy Reaction and Erythema Nodosum Leprosum by Douglas Eulálio Antunes, Isabela Maria Bernardes Goulart, Mayara Ingrid Sousa Lima, Patrícia Terra Alves, Paula Cristina Brígido Tavares, Luiz Ricardo Goulart

“…Leprosy reactions are acute immunological events that occur during the evolution of chronic infectious disease causing neural damage and disabilities. A study using blood samples of 17 leprosy reaction patients and 17 reaction-free was carried out by means of associations between antigens, receptors, and expression of cytokines, using path analysis providing new insights into the immunological mechanisms involved in triggering leprosy reactions. …”
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Study on Roof Presplitting Mechanism and Deformation Control of Reused Roadway in Compound Soft Rock by Roof Presplitting Approach by Fuzhou Qi, Dangwei Yang, Xinming Li, Bin Li, Yingying Zhai, Shuisheng Yu

“…The results show that when the fissure interval is 1 m, the peak value of the horizontal stress reaches 10~12 MPa, and the stress concentration factor is 1.8~2.2, which promotes fracture expansion and transfixion and controls plastic damage development on both sides of a fracture. The elastic strain energy of the reused roadway is reduced to 32.7% of the peak value. …”
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Role of the Neutrophil-to-Lymphocyte Ratio at the Time of Arrival at the Emergency Room as a Predictor of Rhabdomyolysis in Severe Trauma Patients by Jin Chul Bae, Kyung Hoon Sun, Yong Jin Park

“…Purpose In patients with trauma, rhabdomyolysis (RM) can lead to fatal complications resulting from muscle damage. Thus, RM must be immediately diagnosed and treated to prevent complications. …”
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Effects of melatonin supplementation on oxidative stress, and inflammatory biomarkers in diabetic patients with chronic kidney disease: a double-blind, randomized controlled trial by Sara Sadeghi, Amirahmad Nassiri, Monir Sadat Hakemi, Fatemeh Hosseini, Fatemeh Pourrezagholie, Fatemeh Naeini, Aylar Nadiri Niri, Hossein Imani, Hamed Mohammadi

“…It has been demonstrated that the natural antioxidant melatonin reduces inflammation and oxidative damage in renal tissues. Given the lack of robust evidence, this double-blind clinical trial sought to investigate the effects of melatonin supplementation on oxidative stress and inflammatory markers in diabetic CKD patients. …”
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The Deformation Behavior and Failure Modes of Surrounding Rock after Excavation: A Experimental Study by Jinping Liang, Haoyong Jing, Xiaorui Li, Gongyu Hou

“…According to AE results and the failure of opening the boundary, the increase of unloading rate triggers and exacerbates the damage of the specimen under high in situ stress conditions. …”
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Seasonal profile of trace metal contamination (Hg, Cd, Pb and Al) and biological contamination of atmospheric air in the city of Kinshasa, Democratic Republic of the Congo by M. T. Mondo, I. C. Nsimanda, Willy LUSASI SWANA, K. C. Mulaji, K. V. Pwema, E. A. D. Musibono

“… Introduction Unpleasant fumes, odours, reduced visibility, health issues from pollutants, and property damage caused by dust and corrosive gases are significant challenges in urban and industrial areas. …”
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Early Detection of Microvascular Changes in Patients with Diabetes Mellitus without and with Diabetic Retinopathy: Comparison between Different Swept-Source OCT-A Instruments by Stela Vujosevic, Caterina Toma, Edoardo Villani, Valentina Gatti, Marco Brambilla, Andrea Muraca, Maria Chantal Ponziani, Gianluca Aimaretti, Alessandro Nuzzo, Paolo Nucci, Stefano De Cilla’

“…Further, larger longitudinal studies are needed to better understand microvascular damage at very early stages of diabetic retinal disease and to define the strengths and weaknesses of different OCT-A devices.…”
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Hepatic Abnormal Secretion of Apolipoprotein C3 Promotes Inflammation in Aortic Dissection by Xinghui Zhuang, Mohammad Zarif, Yue Shen, Zhaofeng Zhang, Jian He, Linfeng Xie, Qingsong Wu, Xinfan Lin, Keyuan Chen, Yue Tian, Yong Lin, Yuling Zhang, Ziwen Cai, Zhihuang Qiu, Liangwan Chen

“…Background Apolipoprotein C3 (apo C3) is primarily secreted by the liver and is involved in promoting sterile inflammation and organ damage under pathological conditions. Previous studies have shown that apo C3 is abundant in the plasma exosomes of patients with aortic dissection (AD), but its specific role in AD remains unclear. …”
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Developing AI Smart Sprayer for Punch-Hole Herbicide Application in Plasticulture Production System by Renato Herrig Furlanetto, Ana Claudia Buzanini, Arnold Walter Schumann, Nathan Shawn Boyd

“…Despite these limitations, the smart sprayer effectively minimized off-target herbicide application without causing crop damage. This precision approach reduces chemical inputs and minimizes the potential environmental impact, representing a significant advancement in sustainable plasticulture weed management.…”
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Patellofemoral mechanics after uniplane open wedge high tibial osteotomy is superior to those after biplane open wedge high tibial osteotomy by Yi Zheng, Bin Yang, Decheng Meng, Zhijie Wang, Naihao Pan, Chen Feng, Juan Wang

“…Conclusion Uniplane OWHTO would induce lower contact stress and larger contact area on the patellofemoral surface than biplane OWHTO during walking and sitting-to-standing, which may cause less mechanical pain and secondary damage to the articular cartilage. Therefore, uniplane OWHTO might be a better option for patients with anterior knee pain and/or PFJ degeneration.…”
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Urinary Uromodulin Levels and UMOD Variants in Black South Africans with Hypertension-Attributed Chronic Kidney Disease by Nolubabalo Unati Nqebelele, Caroline Dickens, Therese Dix-Peek, Raquel Duarte, Saraladevi Naicker

“…Patients with chronic kidney disease (CKD) have reduced urinary uromodulin levels secondary to tubular damage. Genome wide association studies identified significant single nucleotide polymorphism (SNP) associations with CKD at the uromodulin (UMOD) locus. …”
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Molecular Detection of Panton Valentine Leukocidin Toxin in Clinical Isolates of Staphylococcus aureus from Kiambu County, Kenya by Sani Iliya, Jonathan Mwangi, Ronald Maathai, Mary Muriuki, Christopher Wainaina

“…MRSA produces PVL toxins through lukS and lukF proteins causing tissue necrosis by damaging membrane of the defense cells. Presence of PVL toxin was tested from the 54 S. aureus clinical isolates obtained from Thika and Kiambu Level 5 Hospitals, in Kiambu County, Kenya, by Geno Type® MRSA assay (Hain Life Science, Nehren, Germany). …”
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Estimates of critical loads and exceedances of acidity and nutrient nitrogen for mineral soils in Canada for 2014–2016 average annual sulfur and nitrogen atmospheric deposition by H. Cathcart, J. Aherne, M. D. Moran, M. D. Moran, V. Savic-Jovcic, P. A. Makar, A. Cole

“…Parameterisation of the model for Canadian ecosystems was considered with attention to the selection of the chemical criterion for damage at a site-specific resolution, with comparison between protection levels of 5 % and 20 % growth reduction (approximating commonly chosen base-cation-to-aluminum ratios of 1 and 10, respectively). …”
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Farmers’ Perceptions of Mexican Bean Weevil, Zabrotes subfasciatus (Boheman), and Pest Management Practices in Southern Ethiopia by Tariku Mesele, Kumela Dibaba, Esayas Mendesil

“…The majority of the farmers had knowledge about the Mexican bean weevil; they could identify damaged seeds based on the ‘holes’ on the seed (72.3%) and circular ‘windows’ on the seed (20.0%). …”
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Neurofilament Light Chain Assessment in Type 2 Diabetic Patients with Distal Symmetrical Polyneuropathy by Israa Abdelmalik Salem, Sura Ahmed Abdulsattar, Haider Fadhil Alrubaye

“…Conclusion: The serum level of the neurofilament light chain was affected by the presence of distal symmetric polyneuropathy although as a clinical condition, it is associated with axonal damage, it was found that it could not be used for the prediction of distal symmetric polyneuropathy. …”
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Quantifying the Impact of Climate Change and Forest Management on Swedish Forest Ecosystems Using the Dynamic Vegetation Model LPJ‐GUESS by John Bergkvist, Fredrik Lagergren, Md. Rafikul Islam, David Wårlind, Paul A. Miller, Maj‐Lena Finnander Linderson, Mats Lindeskog, Anna Maria Jönsson

“…Our results highlight differences in the predisposition to storm damage among forest policy scenarios, which were most pronounced in southern Sweden, with increases of 61%–76% in Business‐As‐Usual, 4%–11% in Adaptation and Resistance, and decreases of 7%–12% in EU‐Policy when comparing 2081–2100 to 2001–2020.…”
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Cell-free DNA: a metabolic byproduct with diagnostic and prognostic potential in rheumatic disorders by Fancheng Liu, Fancheng Liu, Yazhen Su, Yazhen Su, Xinling Liu, Li Zhao, Li Zhao, Zewen Wu, Zewen Wu, Yang Liu, Yang Liu, Liyun Zhang, Liyun Zhang

“…Currently, increased levels of cfDNA are noted in a range of rheumatic disorders. Inflammatory damage in patients with rheumatic diseases promotes the release of cfDNA, while potential abnormalities in cfDNA metabolism further increase its levels. …”
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THE OCCURRENCE OF CONTRACTURE AND THE SEVERITY OF BURN INJURIES AMONG BURN PATIENTS TREATED AT DR. SOETOMO GENERAL ACADEMIC HOSPITAL, SURABAYA, INDONESIA (2020-2022) by Gifta Marshanda Qanitah Hamiseno, Iswinarno Doso Saputro, Diah Mira Indramaya, Lobredia Zarasade

“…Abstract: Introduction: Burn injuries are a worldwide issue and can happen for many reasons, often causing skin damage that leads to deformities and movement difficulties. …”
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