High-coverage whole-genome sequencing of a Jakun individual from the “Orang Asli” Proto-Malay subtribe from Peninsular Malaysia by Wai-Sum Yap, Alvin Cengnata, Woei-Yuh Saw, Thuhairah Abdul Rahman, Yik-Ying Teo, Renee Lay-Hong Lim, Boon-Peng Hoh

“…From the whole-genome sequence data, we identified 825 damaging and deleterious nonsynonymous single-nucleotide polymorphisms (nsSNVs) affecting 720 genes. …”
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Effectiveness of the Federal ‘Clean Air’ Project to Improve Air Quality in the Most Polluted Russian Cities by Roman V. Gordeev, Anton I. Pyzhev, Ekaterina A. Syrtsova

“…However, to further improve project performance, it is essential to base project KPIs on estimates of air pollution-related health damage and economic losses.…”
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Evaluation of amoebicidal potential of Paneth cell cryptdin-2 against Entamoeba histolytica. by Simran Preet, Sanjay Bharati, Geeta Shukla, Ashwani Koul, Praveen Rishi

“…Scanning electron microscopy as well as phase contrast microscopic investigations of cryptdin-2 treated trophozoites revealed that the peptide was able to induce significant morphological alterations in terms of membrane wrinkling, leakage of the cytoplasmic contents and damaged plasma membrane suggesting a possible membrane dependent amoebicidal activity. …”
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Adrenal Disorders and the Paediatric Brain: Pathophysiological Considerations and Clinical Implications by Vincenzo Salpietro, Agata Polizzi, Gabriella Di Rosa, Anna Claudia Romeo, Valeria Dipasquale, Paolo Morabito, Valeria Chirico, Teresa Arrigo, Martino Ruggieri

“…., delayed myelination and brain atrophy) due to potential corticosteroid-related myelin damage in the developing brain and the possible impairment of limbic system ontogenesis. …”
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Anticancer activity of Ilex khasiana, a rare and endemic species of holly in Northeast India, against murine lymphoma by Charles Lalnunfela, Pawi Bawitlung Lalthanpuii, Hmar Tlawmte Lalremsanga, Zothansiama, Chhaihlo Lalmuansangi, Mary Zosangzuali, Nachimuthu Senthil Kumar, Tochhawng Lalhriatpuii, Kholhring Lalchhandama

“…Alkaline comet assay showed that the plant extract effectively induced DNA damage, producing a tail length of 11.89 μm and Olive moment of 2.36 at 250 mg/kg bwt, the most effective dosage. …”
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Experimental Study of Size Effects on the Deformation Strength and Failure Characteristics of Hard Rocks under True Triaxial Compression by Qiang Han, Yaohui Gao, Yan Zhang

“…The size effect of deformation and failure characteristics under TTC are not obvious, including stress-strain curves, Young’s modulus, peak strains, failure angles, and macrofailure mode. However, the damage stress (σcd) and peak strength (σp) have obvious size effect; that is, the smaller the sample size is, the higher the strength is. …”
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Amorphization and siliconization of silicon carbide as a first wall material by Aritra De, Jerome Guterl, Zachary Bergstrom, Tyler Abrams, Gregory Sinclair, John David Elder, Dmitry Rudakov

“…Coupled simulation of surface model and impurity transport demonstrates amorphization of crystalline SiC exposed to L-mode plasma due to the accumulation of displacement damages under ion irradiation. This affects the lifetime of SiC plasma facing components. …”
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Carthamin yellow-loaded glycyrrhetinic acid liposomes alleviate interstitial fibrosis in diabetic nephropathy by Yifei Wang, Wenfang He, Peiyao Ren, Li Zhao, Danna Zheng, Juan Jin

“…In DN rats, treatment with CY-loaded GA liposomes significantly alleviated kidney damage, improved kidney function, reduced collagen deposition and fibrosis, and downregulated TGF-β1 expression, showing superior effects compared to Vitamin E or CY alone. …”
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Skatole Alleviates Osteoarthritis by Reprogramming Macrophage Polarization and Protecting Chondrocytes by Weiyun Wang, Yaru Chu, Yunkun Lu, Jie Xu, Weixuan Zhao, Zhuo Liang, Xueqiang Guo, Lingling Xi, Tao Han, Yaping Shen, Wenjuan Song, Yanhua Tang, Mengnan Wen, Zhuang Qian, Lei Wang, Zhenlin Fan, Guangdong Zhou, Wenjie Ren

“…In vivo experiments demonstrated that skatole administration markedly reduced synovitis and cartilage damage in both destabilization of medial meniscus (DMM)-induced OA mice and monosodium iodoacetate (MIA)-induced OA rats. …”
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Plant Growth Promoting Rhizobacteria for Biocontrol of Tomato Bacterial Wilt Caused by Ralstonia solanacearum by Habtamu Mekonnen, Mulugeta Kibret, Fassil Assefa

“…Bacterial wilt induced by Ralstonia solanacearum is one of the most damaging and widespread diseases of tomatoes in the world. …”
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Effectiveness of the entomopathogenic fungus Alternaria murispora and the predatory ladybird Harmonia convergens in controlling Phenacoccus solenopsis (Tinsley) by Mohamed El Aalaoui, Said Rammali, Said Rammali, Fatima Zahra Kamal, Fatima Zahra Kamal, Gabriela Calin, Viorica Rarinca, Viorica Rarinca, Viorica Rarinca, Luminita Diana Hritcu, Alin Ciobică, Alin Ciobică, Alin Ciobică, Alin Ciobică, Mohamed Sbaghi

“…IntroductionPhenacoccus solenopsis Tinsley (Hemiptera: Pseudococcidae) is a major pest that causes significant damage to many crops worldwide, necessitating effective control methods.MethodsThis study evaluated five treatments under screenhouse conditions: untreated control, Harmonia convergens (HC) alone, Alternaria murispora (AM) alone, AM+HC, and imidacloprid (positive control). …”
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Histology Assessment of Chitosan–Polyvinyl Alcohol Scaffolds Incorporated with CaO Nanoparticles by Carlos David Grande-Tovar, Jorge Ivan Castro Castro, Lemy Vanessa Barba-Rosado, Paula A. Zapata, Daniel Insuasty, Carlos-Humberto Valencia-Llano

“…Combining these polymers optimizes their advantages while adding metal oxide nanoparticles like calcium oxide (CaO NPs) enhances antimicrobial properties by damaging bacterial membranes. In this study, we obtained the formation of CaO NPs by calcinating eggshells, which were mixed in a polymeric network of CS and PVA to obtain four different membrane formulations for subdermal tissue regeneration. …”
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Association between exposure to environmental pollutants and increased oral health risks, a comprehensive review by Li Zhu, Mengchen Tang, Yinyin Cai, Yinyin Cai, Panpan Wang, Panpan Wang

“…It is also associated with adverse inflammatory responses and tissue damage in periodontal tissues by causing oxidative stress, potentially leading to periodontitis. …”
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Zoning and assessing the potential for landslide in the Shidri Chach basin using the ANP model by aghail madadi, ebrahim beheshti javid, nazfar aghazadeh

“…During the last years, following an increase in damages due to occurrence of landslides, human has decided to reduce such losses. …”
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Sex-specific associations of prenatal Chinese famine exposure with cataract risk at age sixty: a cross-sectional study by Yuanyou Xia, Xiaoyang Xu, Siyao Wang

“…Prenatal nutrition may cause irreversible damage to the development of the ocular crystalline lens. …”
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Cytotoxicity and genotoxicity of orthodontic bands after aging: an in-vitro study by Maryam Karandish, Bahar Khademi, Golnaz Ziaei, Nasrollah Erfani, Leila Moezi, Zahra Faghih

“…Regarding genotoxicity, DNA damage was evident for both brands at pH = 4.5, however, AO molar bands demonstrated longer comet tails compared to 3 S-dental molar bands. …”
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Characterization of resistance of winter wheat varieties to Fusarium head blight by T. Yu. Gagkaeva, A. S. Orina, O. P. Gavrilova, I. B. Ablova, L. A. Bespalova

“…We used the following set of disease assessment parameters: the percentage of visually and latent Fusarium-damaged grains (FDG); the DNA content of Fusarium fungi; the productivity of inoculated plants compared with non-inoculated plants; and the amount of mycotoxins in the grain. …”
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The mystery of methylene blue and its role in managing post-cardiac surgery vasoplegic shock by Mohamed Elbayomi, Oliver Dewald, Presheet Pathare, Markus Kondruweit, Rene Tandler, Michael Weyand, Christian Heim

“…In-hospital mortality was not significantly different between the two groups (38% in the MB group vs. 43% in the control group).Conclusion Early postoperative administration of methylene blue in patients with vasoplegic syndrome shortens intensive care unit stay and contributes to less end-organ damage.…”
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Dry eye syndrome, associated with the wearing of contact lenses. Features of the therapeutic approach by E.A. Egorov

“…The balanced composition of these innovative eye drops, their hypotonicity, absence of a preserving agent provides a pronounced moisturizing protective effect, reduces the risk of damage to the cells of the epithelium of the ocular surface and eye tissues, prevents the development of eye surface diseases and increases the adherence of patients to contact correction.…”
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Early impairment of magnocellular visual pathways mediated by isolated-check visual evoked potentials in primary open-angle glaucoma: a cross-sectional study by Yangfan Yang, Minbin Yu, Zidong Chen, Qiaona Ye, Yanmei Fan, Pingping Liu, Zitian Liu, Kezheng Xu

“…The areas under ROC of 16% DOM were 0.780 (sensitivity 80.0%, specificity 63.3%) with the cut-off SNR of 2.07.Conclusions The MC visual pathway was damaged in the early stage of POAG. The SNRs at 8% and 32% DOM of MC-biased stimulation were significantly correlated with temporal-side RNFL thickness in early POAG, which helped in understanding the mechanisms of visual impairment in the early stage of POAG.…”
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