Acupuncture mediates the “gut–testis axis” to improve asthenozoospermia by Jianheng Hao, Jianheng Hao, Huichao Xu, Boya Chang, Jia Ren, Haijun Wang, Laixi Ji, Laixi Ji

“…Further validation was obtained by performing a fecal microbiota transplantation (FMT).ResultsAcupuncture improved the sperm quality; ameliorated testicular pathology; increased serum testosterone (T), follicle-stimulating hormone (FSH), and luteinizing hormone (LH) levels; and repaired gut and blood–testis barrier damage in asthenozoospermic mice. The abundances of Bacteroidota, Firmicutes, Faecalibaculum, and Dubosiella were associated with sperm motility, as shown by a gut microbiome analysis. …”
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A Field Study of the Effect of Noise and Whole-Body Vibration Exposure on Heavy Equipment Drivers’ Auditory System Function by Seyyed Mohammad Javad Golhosseini, Mohsen Aliabadi, Rostam Golmohammadi, Maryam Farhadian, Mehdi Akbari

“…Conclusion: The results of this study showed the damaging consequences of exposure to noise and WBV on the auditory response; In addition, the present study provided evidence of synergistic effects of combined exposure to noise and WBV on heavy equipment drivers.…”
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In vitro immunomodulatory effects of thymol and cinnamaldehyde in a pig intestinal epithelial cell line (IPEC-J2) by C. Shen, L.G. Christensen, P.B. Rasmussen, K.M. Kragh

“…This study evaluated the in vitro immune modulating effects of thymol and cinnamaldehyde blend (TCB) in a porcine gut epithelial cell line (IPEC-J2), with or without cellular damage caused by challenge with lipopolysaccharides. …”
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Protective effects of apigenin in neurodegeneration: An update on the potential mechanisms by Ali Mohammadkhanizadeh, Mohammad Sheibani, Soroush Taherkhani, Davood Nourabadi, Seyed Mahdi Mohamadi-Zarch, Farnaz Nikbakht, Yaser Azizi

“…Apigenin has been demonstrated to scavenge ROS, thereby reducing oxidative stress and mitigating the damage to neurons. Inflammation is another key feature of neurodegenerative diseases, and apigenin has been found to possess anti-inflammatory properties. …”
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Metabolism: A Novel Shared Link between Diabetes Mellitus and Alzheimer’s Disease by Yanan Sun, Cao Ma, Hui Sun, Huan Wang, Wei Peng, Zibo Zhou, Hongwei Wang, Chenchen Pi, Yingai Shi, Xu He

“…Thus, the brain may be more susceptible to oxidative damage than the rest of the body. Emerging evidence suggests that both oxidative stress and mitochondrial dysfunction are related to amyloid-β (Aβ) pathology. …”
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Deep proteomics and network pharmacology reveal sex- and age-shared neuropathic pain signatures in mouse dorsal root ganglia by Sabrina Grundtner, Julia R. Sondermann, Feng Xian, Daniel Malzl, Daniel Segelcke, Esther M. Pogatzki-Zahn, Jörg Menche, David Gómez-Varela, Manuela Schmidt

“…Protein network and multidimensional analysis uncovered distinct hubs of sex- and age-shared biological pathways impacted by neuropathic pain, such as neuronal activity and synaptic function, DNA-damage, and neuroimmune interactions. Taken together, our results capture the complexity of nerve injury-associated DRG alterations in mice at the network level, moving beyond single-candidate studies. …”
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Activated Human Umbilical Cord Blood Platelet-Rich Plasma Enhances the Beneficial Effects of Human Umbilical Cord Mesenchymal Stem Cells in Chemotherapy-Induced POF Rats by Jiawei Wang, Yunxiao Zhao, Fengque Zheng, Nana Ma, Rongyan Qin, Weili Qin, Bo Liu, Aiping Qin

“…The combined transplantation of HucMSCs and ucPRP resulted in more stem cells being retained in the ovaries of POF rats, the estrus cycle of the POF rats being restored, the levels of serum E2, AMH, and FSH improving, and damaged follicles beginning to grow. Finally, we confirmed that the potential mechanism of the combination of HucMSCs and ucPRP to rescue the ovarian function of POF rats is to promote ovarian angiogenesis and to promote the proliferation and reduce the apoptosis of ovarian granulosa cells. …”
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Establishment Methods and Application Evaluation of Animal Models in Reproductive Toxicology Research by HUANG Dongyan, WU Jianhui

“…Research includes evaluating the damaging effects of test substances on reproductive function of parents and the toxicity evaluation of offspring embryos. …”
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Paeonol Attenuates Methotrexate-Induced Cardiac Toxicity in Rats by Inhibiting Oxidative Stress and Suppressing TLR4-Induced NF-κB Inflammatory Pathway by Abdulla Y. Al-Taher, Mohamed A. Morsy, Rehab A. Rifaai, Nagwa M. Zenhom, Seham A. Abdel-Gaber

“…MTX cardiac toxicity was induced at the end of the fifth day of the experiment, with or without paeonol pretreatment. MTX-induced cardiac damage is evidenced by a distortion in the normal cardiac histological structure, with significant oxidative and nitrosative stress shown as a significant increase in NADPH oxidase-2, malondialdehyde, and nitric oxide levels along with a decrease in reduced glutathione concentration and superoxide dismutase activity compared to the control group. …”
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The Impact of Anti-Diabetics on Platelets Function and Cardiovascular Outcomes in Type 2 Diabetes Mellitus: A Narrative Review by Muthanna Zaki, Mohammed Abed, Fawaz Alassaf

“…We realized various mechanisms responsible for enhanced platelet aggregation in T2DM, represented by immature, large, or activated platelets in the altered metabolic environment, against the background of vascular damage in DM. In parallel, analyzing the impact of anti-diabetics on platelet aggregation revealed that most of them are believed to have favorable protective effects against thrombotic disorders via reducing platelet activation and aggregation. …”
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Olfactory Impairment and Recovery in Zebrafish (<i>Danio rerio</i>) Following Cadmium Exposure by Chiara Maria Motta, Rosa Carotenuto, Chiara Fogliano, Luigi Rosati, Pabitra Denre, Raffaele Panzuto, Rossana Romano, Gianluca Miccoli, Palma Simoniello, Bice Avallone

“…The exposed fish performed poorly, failing to reach food in five consecutive trials. However, lamellar damage was reduced after the recovery period, and their performance improved, becoming comparable to the control group. …”
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The box tree moth Cydalima perspectalis: a review of biology, invasiveness, management practices and future perspectives of control strategy in Europe by Marta Budziszewska, Paweł Krystian Bereś

“…Since its initial detection in Europe in 2006, C. perspectalis has spread rapidly, causing widespread damage to both ornamental and wild boxwood populations. …”
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Failure of cargo aileron’s actuator by G. Zucca, M. Amura, L. Allegrucci, M. Bernabei

“…During a ferry flight, in a standard operation condition and at cruising level, a military cargo experienced a double hydraulic system failure due to a structural damage of the dual booster actuator. The booster actuator is the main component in mechanism of aileron’s deflection. …”
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Seepage Behavior of Earth Dams Considering Rainfall Effects by Jong-Wook Lee, Jiseong Kim, Gi-Chun Kang

“…In general, reservoir water levels sharply rise during this period and rock-fill dams are exposed to various types of damages such as soil erosion and piping related to seepage problems. …”
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The diagnostic conundrum of late-onset developmental regression in child psychiatry: case series by Shalu Elizabeth Abraham, Sakhardande Kasturi Atmaram, Poornima Khadanga, Nirmalya Mukherjee, Rajendra Kiragasur Madegowda, Harshini Manohar

“… Background Developmental regression in children, in the absence of neurological damage or trauma, presents a significant diagnostic challenge. …”
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Effects of hypoxia on the heart of the juvenile four-finger threadfin (Eleutheronema tetradactylum) based on physiological indicators and transcriptome analysis by Yi Lu, Eric Amenyogbe, Ye- Yang, Zhong-liang Wang, Zhong-liang Wang, Zhong-liang Wang, Jing-hui Jin, Rui-tao Xie, Eric Kwabena Droepenu, Jian-sheng Huang, Jian-sheng Huang, Jian-sheng Huang

“…Histological analysis revealed structural damage in myocardial fibers under hypoxia, with increasing severity over time. …”
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Phosphorylation of histone H3Ser10 in plant cell division by D. B. Loginova, O. G. Silkova

“…It has been shown that this type of modification is required for activation of transcription, DNA damage repair, recombination and also for chromosome condensation and segregation. …”
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H-NS controls the susceptibility of Escherichia coli to aminoglycosides by interfering its uptake and efflux by Qiuru Chen, Yulei Liang, Yanbin Dong, Junling Cui, Kun He, Xiaoyuan Ma, Jinfeng Zhao, Jinfeng Zhao, Yajun Zhai, Yajun Zhai, Li Yuan, Li Yuan, Li Yuan, Li Yuan

“…Further studies displayed that the absence of hns caused damage to the bacterial outer membrane and increased the expression levels of porin-related genes, such as ompC, ompF, ompG, and ompN, thus obviously enhancing aminoglycosides uptake of strain EΔhns. …”
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Dying to be famous: retrospective cohort study of rock and pop star mortality and its association with adverse childhood experiences by Mark A Bellis, Karen Hughes, Olivia Sharples, Tom Hennell, Katherine A Hardcastle

“…Adverse experiences in early life may leave some predisposed to health-damaging behaviours, with fame and extreme wealth providing greater opportunities to engage in risk-taking. …”
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Construction and application of optimized model for mine water inflow prediction based on neural network and ARIMA model by Xiaoyu Gong, Bo Li, Yu Yang, MengHua Li, Tao Li, Beibei Zhang, Lulin Zheng, Hongfei Duan, Pu Liu, Xin Hu, Xin Xiang, Xinju Zhou

“…In order to better predict the amount of water surging in mines and to provide an important basis for mine water damage prevention work, based on the time series data of mine water influx from January 2020 to February 2023 in Northern Guizhou Province Longfeng Coal Mine, the BP-ARIMA prediction model was established by combining the BP neural network model and ARIMA autoregressive sliding average model, It also predicted the mine influx for a total of 6 months from July 2022 to February 2023, and compared the prediction results with four models, namely, BP neural network model, ARIMA autoregressive sliding average model, traditional method of Large well method, and GM(1,1) grey model, and used the absolute relative error as the calculation of model accuracy. …”
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