Synergism of d-limonene and temozolomide on migratory and apoptotic behaviors of human glioblastoma cell lines by Megha Gautam, Reema Gabrani

“…Methods: The effects of the combined treatment of DL and TMZ were assessed on various cellular aspects, including cell viability, anchorage-independent cell growth, and DNA damage. Furthermore, the influence of this combination on cell cycle progression, cell migration, and cell death was also investigated. …”
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Comparative evaluation of funduscopy, PCR and serology in the diagnosis of ocular toxoplasmosis at ECWA Eye Hospital, Kano by Biodun Bintu Adebakin, Mayor Orezime Atima, Ugbede Idakwo, Jamilu Abubakar Bala, Alhasan Sharif Abdullahi, Auwal Bello Muhammad, Jah Douglas Pam, Emeka John Dingwoke, Florence Olufunke Darda

“…Accurate diagnosis is essential to prevent retinal damage and optimise treatment. This study aimed to compare three diagnostic methods funduscopy, serology (ELISA), and PCR in detecting ocular toxoplasmosis in patients at ECWA Eye Hospital, Kano, Nigeria.Methods and analysis A total of 264 patients suspected of having ocular toxoplasmosis were enrolled. …”
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Increased TLR4 Expression Aggravates Sepsis by Promoting IFN-γ Expression in CD38−/− Mice by Qi Li, Chenyi Wu, Zhenlong Liu, Huiqing Zhang, Yuna Du, Yuxiang Liu, Kuangyu Song, Qiaofa Shi, Rong Li

“…Our results showed more aggravated kidney damage in CD38−/− mice than in WT mice, accompanied with an increase of proinflammatory cytokine expression. …”
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The Application of Numerical Simulation in Debris Flow Disaster Early Warning: A Case Study of Shiyang Gully, China by Hao Zheng, Lanlan Guo, Jifu Liu, Bin Chen, Lianyou Liu

“…Simulation results showed that cumulative rainfall exceeding 90 mm or rainfall intensity surpassing 200 mm/8 h significantly increases debris flow depth, impact force, and affected areas, leading to severe structural damage. Expanding the rainfall range to the entire basin further amplifies disaster risks, increasing both inundation depth and exposed elements. …”
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A smartphone application to objectively monitor music listening habits in adolescents by Danique E. Paping, Jantien L. Vroegop, Simone P. C. Koenraads, Carlijn M.P. le Clercq, André Goedegebure, Robert J. Baatenburg de Jong, Marc P. van der Schroeff

“…We consider a smartphone application to monitor listening habits of added value in future research investigating the possible damaging effects of PLDs on hearing acuity. Graphical abstract…”
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USP25 attenuates anti-GBM nephritis in mice by negative feedback regulation of Th17 cell differentiation by Ranran Xu, Fei Huang, Qingquan Liu, Yongman Lv, Liu Hu, Qian Zhang

“…Similar trends were observed in vitro.Conclusion USP25 plays a crucial role in mitigating renal histopathological and functional damage during anti-GBM GN in mice. This protective effect is primarily attributed to USP25’s ability to inhibit the differentiation of naïve CD4+ T cells into Th17 cells. …”
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THE POSSIBILITIES OF TREATMENT OF PATIENTS WITH MALIGNANT NEOPLASMS OF THE FEMALE REPRODUCTIVE SYSTEM WITH METASTATIC BRAIN LESION by A. M. Zaytsev, E. G. Novikova, O. N. Kirsanova, M. I. Kurzhupov, E. A. Potapova

“…However, over the past 20 years, incidence of secondary brain damage increased 6.5 times. Genital tumor metastasis in the brain is around 5%. …”
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Research Progress on the Relationship between Ischemic Stroke and Immunoinflammatory Factors by Qiang TANG, Huilin HUANG, Luwen ZHU, Hongyu LI, Jiyao ZHANG, Ping QIN, Xia YIN, Jiashuai LI

“…FasL can induce cell apoptosis and immune inflammatory response, and microglia and T lymphocytes all play protective or damaging roles to varying degrees, which can greatly broaden the treatment thinking and plan of ischemic stroke and meet the diversified challenges in the treatment of stroke. …”
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Ophthalmic products with extracellular matrix components. Their effectiveness in the process of corneal repair in neurotrophic, herpetic, recurrent keratitis and erosions by D.Yu. Maychuk, A.A. Tarkhanova, I.A. Pronkin

“…The multicomponent composition of SPHERO®oko provides the microenvironment necessary for the cells of the eye tissues, contributing to the processes of their proliferation and differentiation and, as a final result, to the acceleration of reparative regeneration of tissues damaged as a result of injury or infectious-inflammatory process. …”
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Sustainable Valorization of Rice Straw into Biochar and Carbon Dots Using a Novel One-Pot Approach for Dual Applications in Detection and Removal of Lead Ions by Jagpreet Singh, Monika Bhattu, Meenakshi Verma, Mikhael Bechelany, Satinder Kaur Brar, Rajendrasinh Jadeja

“…Lead (Pb) is a highly toxic heavy metal that causes significant health hazards and environmental damage. Thus, the detection and removal of Pb²⁺ ions in freshwater sources are imperative for safeguarding public health and the environment. …”
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Phthalates esters disrupt demersal fish behavior: Unveiling the brain-gut axis impact by Liuqingqing Liu, Xinyao Li, Xianxiang Luo, Xiao Wang, Linjia Liu, Zixi Yuan, Cuizhu Sun, Hao Zheng, Elvis Genbo Xu, Fengmin Li

“…This accumulation led to oxidative damage, inflammatory responses, and neurodegenerative changes in the optic tectum, resulting in cholinergic system dysfunction. …”
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Assessment of the risk of rapid progression of chronic kidney disease by L.D. Denova, D.D. Ivanov

“…Patients were divided into 3 groups: group 1 (n = 46) — individuals with stage 1–3 CKD who had a CCI ≤ 2, group 2 (n = 45) — patients with stage 1–3 CKD who had CCI ≥ 3, and group 3 (n = 32) — people without CKD risk factors and wi­thout symptoms of kidney damage. Results. The results of the study showed that the linear regression between uAlb/uUmod and eGFR in groups 1 and 2 is statistically significant (p < 0.05). …”
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Research on the numerical simulation of dynamic explosion shock wave propagation characteristics between floors by Ke Wu, Bo Chen, Hao Li, Yunfeng Zhang, Damin Zhang, Yixuan Wu, Yaguang Sui

“…This study addresses the assessment of dynamic explosive shock wave loads in building damage evaluation. Utilizing numerical simulation methods, we investigated the propagation process of shock waves between building floors, capturing the evolution of their wavefronts. …”
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Monitoring the Spread of Multidrug-Resistant <i>Escherichia coli</i> Throughout the Broiler Production Cycle by Victor Dellevedove Cruz, Danilo Henrique Rabaçal Alves, Jamile Kellen de Souza, Maísa Fabiana Menck-Costa, Bruno Henrique Dias de Oliva, Ana Angelita Sampaio Baptista, Alexandre Oba, Fabrizio Matté, Kácio Emílio Borges Baierle, Sérgio Paulo Dejato da Rocha, Kelly Cristina Tagliari de Brito, Benito Guimarães de Brito, Gerson Nakazato, Marcio Costa, Renata Katsuko Takayama Kobayashi

“…The monitoring of antimicrobial virulence and resistance genes are tools that have come to assist the breeding of these animals, directing possible treatments as already used in human medicine and collecting data to demonstrate possible dissemination of multidrug-resistant strains that may cause damage to industry and public health. This work aimed to monitor broiler farms in southern Brazil, isolating samples of <i>E. coli</i> and classifying them according to the profile of resistance to antimicrobials of interest to human and animal health. …”
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Clinical Outcomes and Complication Rates of Endodontically Treated Teeth with Fixed Dental Prostheses: A Retrospective Study by Sarah Aloqayli, Hanin Alsalhi, Ali Alenezi

“…<b>Background/Objectives</b>: Endodontically treated teeth (ETT) often have significant structural damage and require multiple reinforcing methods during the reconstruction process. …”
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Morphological and Chemical Changes in the Hemolymph of the Wax Moth <i>Galleria mellonella</i> Infected by the Entomopathogenic Fungus <i>Conidiobolus coronatus</i> by Mieczysława Irena Boguś, Agata Kaczmarek, Anna Katarzyna Wrońska, Mikołaj Drozdowski, Lena Siecińska, Ewelina Mokijewska, Marek Gołębiowski

“…It remains an open question whether substances appearing in the hemolymph of infected insects are a product of the fungus or if they are released from the insect tissues damaged by the growing hyphae.…”
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OVERVIEW OF THE EPIDEMIC SITUATION ON CERTAIN INFECTIOUS ANIMAL DISEASES IN THE RUSSIAN FEDERATION IN 2018 by N. S. Bardina, A. V. Varkentin, A. K. Karaulov

“…The specified above infections cause great damage to animal husbandry in the country which has a negative impact on its export potential. …”
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Mathematical Modelling of Host-Pest Interaction in the Presence of Insecticides and Resistance: A Case of Fall Armyworm by Moreen Brenda Gatwiri, Marilyn Ronoh, Cyrus Gitonga Ngari, Dominic Makaa Kitavi

“…Pest control measures should be modified to lower the FAW survival rate and all model parameters contributing to resistance formation by FAW larvae to minimize FAW-host interaction, thus reducing crop damage.…”
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Experimental study on the mechanical properties of modified phosphogypsum at different loading rates by Bo Zhang, Chaohua Xu, Qin Wu, Xiaohui Qin, Jiagang Wei, Zhen Lu

“…As the loading rate increases, the crack initiation stress $${\sigma _{{\text{ci}}}}$$ , damage stress $${\sigma _{{\text{cd}}}}$$ , and peak strength $${\sigma _f}$$ gradually increase, but the increasing amplitude gradually decreases. …”
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Infestation patterns of a major wood boring pest, Psiloptera fastuosa (Buprestidae: Coleoptera) in Tasar, Terminalia arjuna (Myrtales: Combretaceae) plantation by Sumit Mandal, Avishek Dolai, Kartik Chandra Mandal, Amlan Das

“…After hatching, the coleopteran grubs puncture and penetrate the arjuna stem, mature into pupae inside, pass into adults, and exit through emergence holes, causing severe damage to younger plants. Though such infestations are highly fatal, no precautions have been proposed to protect the arjuna plantations. …”
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