The periplasmic protein HslJ is the first-line of defense against oxidative stress in Acinetobacter baumannii by Daniela Scribano, Martina Pasqua, Dolores Limongi, Lucia Nencioni, Anna Teresa Palamara, Cecilia Ambrosi

“…In this study, we demonstrate the pivotal function of HslJ as the first line of defense against oxidative damage induced by hydrogen peroxide (H2O2). Methods An isogenic site-specific hslJ mutant of A. baumannii AB5075 was used to evaluate its sensitivity to H2O2, survival rate in human macrophages, biofilm, cell surface hydrophobicity, and motility. …”
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Extensive In Silico Analysis of ATL1 Gene : Discovered Five Mutations That May Cause Hereditary Spastic Paraplegia Type 3A by Mujahed I. Mustafa, Naseem S. Murshed, Abdelrahman H. Abdelmoneim, Miyssa I. Abdelmageed, Nafisa M. Elfadol, Abdelrafie M. Makhawi

“…The aim of this work was to categorize the most damaging SNPs in ATL1 gene and to predict their impact on the functional and structural levels by several computational analysis tools. …”
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Dynamic 19F-MRI of pulmonary ventilation in lung transplant recipients with and without chronic lung allograft dysfunction by Mary A. Neal, PhD, Saskia Bos, MD, PhD, Charlotte W. Holland, MRCP, Kieren G. Hollingsworth, Gerard Meachery, FRCP, Arun Nair, MD, FRCP, James L. Lordan, FRCP, Andrew J. Fisher, FRCP, PhD, Peter E. Thelwall, PhD

“…Background: By the time chronic lung allograft dysfunction (CLAD), with its main phenotypes bronchiolitis obliterans syndrome (BOS) and restrictive allograft syndrome (RAS), is diagnosed by pulmonary function testing, irreversible damage to the lung allograft may already have occurred. …”
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Hypericin-Mediated Photodynamic Therapy for Head and Neck Cancers: A Systematic Review by Jakub Fiegler-Rudol, Natalia Zięba, Radosław Turski, Maciej Misiołek, Rafał Wiench

“…Photodynamic therapy (PDT) has emerged as a promising alternative, leveraging photosensitizers such as hypericin to selectively target tumour cells with minimal damage to surrounding healthy tissues. <b>Objectives</b>: We aimed to evaluate the efficacy and underlying mechanisms of hypericin-mediated PDT (HY-PDT) in treating head and neck cancers. …”
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Immunological pathogenesis and treatment progress of adenovirus pneumonia in children by Yaowen Liang, Jie Wei, Jianjun Shen, Zihao Liang, Xiuchang Ma, Yuchen Du, Wenxian Qian, Hui Dong, Ping Huang, Apeng Chen, Changhua Yi

“…This cascade results in a cytokine storm, which triggers an inflammatory response and causes lung tissue damage. As a result, the infection may progress to a severe state, potentially leading to multi-organ failure. …”
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Extracellular CIRP Upregulates Proinflammatory Cytokine Expression via the NF-kappaB and ERK1/2 Signaling Pathways in Psoriatic Keratinocytes by Xiu Zhang, Shengbang Wang, Wei Wang, Liumei Song, Shuo Feng, Jingping Wang, Tong Kang, Peiwen Yang, Ning Wang, Pengju Yang, Ruimin Bai, Yongping Shao, Yan Zheng

“…C23, a short peptide derived from CIRP, competitively binds CIRP receptors and reduces damage in inflammatory diseases. However, the effect of eCIRP in psoriasis has not been studied. …”
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Clinical outcomes and anti-inflammatory mechanisms predict maximum heart rate improvement after physical activity training in individuals with psychiatric disorders and comorbid ob... by Pau Soldevila-Matías, Joan Vicent Sánchez-Ortí, Patricia Correa-Ghisays, Vicent Balanzá-Martínez, Gabriel Selva-Vera, Roberto Sanchis-Sanchis, Néstor Iglesias-García, Manuel Monfort-Pañego, Pilar Tomás-Martínez, Víctor M Victor, Benedicto Crespo-Facorro, Constanza San Martin Valenzuela, José Antonio Climent-Sánchez, Rosana Corral-Márquez, Inmaculada Fuentes-Durá, Rafael Tabarés-Seisdedos

“…<h4>Introduction</h4>This study aimed to evaluate the predictive validity and discriminatory ability of clinical outcomes, inflammatory activity, oxidative and vascular damage, and metabolic mechanisms for detecting significant improve maximum heart rate after physical activity training in individuals with psychiatric disorders and obesity comorbid using a longitudinal design and transdiagnostic perspective.…”
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Effect of nanocurcumin (Curcuma longa) on lung histopathology in rats exposed to carbon black by El Roy Achmad Rahmaniabdi, Imam Mustofa, Eka Pramyrtha Hestianah, Widjiati Widjiati, Rochmah Kurnijasanti, Hani Plumeriastuti

“…Conclusion Nanocurcumin administration demonstrates potential in mitigating alveolar septal thickening and fibrosis in rat lungs subjected to carbon black exposure, suggesting a protective role against pulmonary damage from particulate matter. …”
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Clinical Evaluation of Acute Pancreatitis Caused by SARS-CoV-2 Virus Infection by Hulya Vatansev, Mehmet Aykut Yıldırım, Serkan Kuccukturk, Mehmet Ali Karaselek, Cengiz Kadiyoran

“…The rate of pancreatic damage in SARS-CoV-2 infection was found to be 19% (n=29) in our study. …”
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Assessment of 8-hydroxy-2-deoxyguanosine activity, apoptosis, acetylcholinesterase and antioxidant enzyme activity in Capoeta umbla brain exposed to chlorpyrifos by Kirici Mahinur

“…The obtained data indicate a significant increase in the MDA level and inhibition of antioxidant enzymes in the brain (p < 0.05). Considering DNA damage and the apoptotic process, no significant changes were found in 8-OHdG and caspase-3 activity at both doses exposed for 24 h, but a significant increase was detected in both markers at 96 hours compared to the control group (p < 0.05). …”
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Disastrous Mechanism of Water Discharge in Abandoned Gob above the Stope in Mining Extra-Thick Coal Seam by Haixiao Lin, Feng Yang, Zhengzheng Cao, Yue Wang, Xiaojian Jiao

“…With the exploitation of the 3-5# extra-thick coal seam in the Carboniferous system, the scope of overburden damage is greatly increasing, and the mining fracture field is further developed. …”
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Usp11 maintained the survival of marginal zone B cells under ionizing radiation by deubiquitinating DLL1 and JAG2 by Jiaqi Sheng, Depei Wu, Jingzhe Shang, Xiaodan Fu, He Gao, Jianjie Rong, Jun Wang, Jiancheng Hu, Xiaofei Qi

“…In conclusion, Usp11 played a crucial role in modulating immune system damage induced by ionizing radiation, primarily through ubiquitination of Notch ligands. …”
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Using the fuzzy cognitive map in designing a decision support system in diabetes insipidus by fatemeh haghani, alireza shahraki, Mohebali Rahdar

“…But with a faster and timely diagnosis, it can be prevented from progressing and the damage of lack of treatment, which can be irreparable. …”
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Influence of Wheel Profile Wear Coupled with Wheel Diameter Difference on the Dynamic Performance of Subway Vehicles by H. X. Li, A. H. Zhu, C. C. Ma, P. W. Sun, J. W. Yang, K. Q. Zhang

“…Later, the interaction between the effects of WPW and equivalent in-phase WDD on the vehicle dynamic performance was analyzed, and the dynamic response in the presence of coupled damage was compared between the outer and inner wheels. …”
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Strengthening Russia’s International Prestige during the Northern War: Russian Diplomatic Institutions and Instruments by A. V. Topychkanov

“…To limit the dissemination of information damaging Russia’s prestige, Russian diplomats began to use the same instruments of influence (newspapers, magazines, and pamphlets), which European diplomats used at that time: various methods of pressure and bribery, propaganda, and censorship. …”
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Suitability Analysis of Three Quick-Freezing Techniques for Application in Bamboo Shoot Freezing by FAN Zhenmei, SHEN Hui, HU Tenggen, CHENG Lina, YU Lijuan, XU Yujuan, WU Jijun, YU Yuanshan

“…In addition, the structure of vascular bundles was seriously damaged by PSF, resulting in 6.12%-10.47% thawing loss and more serious water migration. …”
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Ishophloroglucin A Isolated from <i>Ishige okamurae</i> Protects Glomerular Cells from Methylglyoxal-Induced Diacarbonyl Stress and Inhibits the Pathogenesis of Diabetic Nephropath... by Chi-Heung Cho, Min-Gyeong Kim, Bomi Ryu, Sang-Hoon Lee

“…IPA protected cells from MGO-induced oxidative stress by inhibiting intracellular MGO accumulation (untreated cells: 1.62 μg/mL, MGO treated cells: 25.27 μg/mL, and IPA 5 μM: 11.23 μg/mL) (<i>p</i> < 0.001) and AGE generation and inhibited MGO-induced renal cell damage via the downregulation of MGO-induced RAGE protein expression (relative protein expression levels of MGO treated cells: 9.37 and IPA 5 μM:1.74) (<i>p</i> < 0.001). …”
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Cyberbullying: Violence in the digital world by Mijatović Marina D.

“…The above mentioned types of abuse can cause permanent and deep traumas, reduce the level of self-confidence of people who are labeled with this type of violence, damage them emotionally and socially. This paper provides a broader picture of the impact of digital violence on all aspects of personality with a special emphasis on the identification of risk factors and the development of prevention with the aim of protecting each individual in the digital environment.…”
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INONDATIONS TORRENTIELLES EN ZONES MONTAGNEUSES AFFÉRENTES AU GOLFE DU MEXIQUE by JEAN-NOËL SALOMON

“…The consequences of these devastating floods were many casualties andmaterial damage over large areas. After a time, erosion processes become more numerous with disastrous soil loss, particularly in mountainous areas (slopes), moreover so, if used for farming or grazing. …”
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The N‐terminal domain of gasdermin D induces liver fibrosis by reprogrammed lipid metabolism by Xue Wang, Chunyou Ning, Xingyi Cheng, Zhengzhong Wu, Dongbo Wu, Xuemei Ding, Cunxiang Ju, Zhihang Zhou, Lingfeng Wan, Wei Zhao, Peiliang Shi

“…Results Doxycycline‐treated GSDMD‐NTki/wt × Alb‐creki/wt mice showed severe liver damage, vacuolation of hepatocytes, increased collagen fibers, and accumulation of lipid droplets. …”
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