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16021
Study of fluidelastic instability in the streamwise and transverse directions through tube array under two-phase flow conditions using pressure effects
Published 2025-01-01“…The fluidelastic instability (FEI) in heat exchanger tubes has been of widespread concern due to its tendency to cause damage to the tubes. Generally, FEI in the transverse direction of the tube occurs earlier than in the streamwise direction, and the intrinsic frequency of the tube as well as the way of tube distribution have a great influence. …”
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16022
Mechanism of dexmedetomidine protection against cisplatin induced acute kidney injury in rats
Published 2024-12-01“…In addition, four serum biochemical indices were measured: histopathological damage in rat kidneys was detected; levels of inflammatory factors, interleukin (IL)-1β, IL-18, IL-6, and tumor necrosis factor alpha, in kidney tissue homogenate of rats were assessed through enzyme-linked immunosorbent assay (ELISA); and levels of NLRP-3, caspase-1, cleaved caspase-1, gasdermin D (GSDMD), and GSDMD-N in kidney tissues of rats were determined via western blotting.Results Dex treatment reduced nephromegaly and serum clinical marker upregulation caused by CP-induced AKI. …”
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16023
Berberrubine protects against cisplatin-induced ototoxicity by promoting folate biosynthesis
Published 2025-01-01“…RNA-seq and qRT-PCR analysis revealed that BB influenced the expression levels of multiple genes (Ccnd2, Reln, Pgf, Mylk3, Ppplr12c, Thbsl), by promoting folate biosynthesis for hearing protection.ConclusionOur findings suggest that BB protects against cisplatin-induced hearing damage by enhancing folate biosynthesis, decreasing intracellular ROS levels, and inhibiting apoptosis.…”
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16024
Therapeutic Role of Protein Tyrosine Phosphatase 1B in Parkinson’s Disease via Antineuroinflammation and Neuroprotection In Vitro and In Vivo
Published 2020-01-01“…PTP1B inhibition also reversed 6-hydroxydopamine- (6-OHDA-) induced downregulation of phospho-cAMP response element-binding protein (p-CREB) and brain-derived neurotrophic factor (BDNF) in SH-SY5Y cells. …”
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16025
Environmental impact assessment of Sadr Double - Deck Highways on the context of residential neighborhoods around
Published 2021-09-01“…Results of the assessment matrix showed that Sadr multi-layer project is confirmed by providing corrective options in activities with high and very high damage. Based on the research findings it was found that the neighborhoods around the Sadr multi-layer highway given the assed dimensions, each have a different susceptibility from the multi-layer Sadr Bridge. …”
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16026
Apathy Is Correlated with Widespread Diffusion Tensor Imaging (DTI) Impairment in Amyotrophic Lateral Sclerosis
Published 2018-01-01“…Using diffusion tensor imaging (DTI) and tract-based spatial statistics (TBSS), here we aimed to quantify the correlation between brain microstructural damage and apathy scores in the early stages of ALS. …”
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16027
Does preeclampsia impact the gut microbiota of preterm offspring during early infancy?
Published 2025-01-01“…Abstract Preeclampsia (PE) is a pregnancy complication characterized by high blood pressure and organ damage. This study investigates the differences in the gut microbiota between preterm neonates born to mothers with PE and those born to mothers without PE (PR), aiming to understand how maternal health conditions like PE influence neonatal gut microbiota. …”
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16028
Physicochemical and functional properties of cassava flour produced by controlled fermentation using mixed culture from various bacteria and yeast
Published 2025-03-01“…Among tuber commodities, cassava is the most easily damaged and has a short shelf life. Flour is an intermediate product that can extend the shelf life of cassava and expand its utilization. …”
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16029
An Enhanced Drone Technology for Detecting the Human Object in the Dense Areas Using a Deep Learning Model
Published 2022-01-01“…This study focused on detecting wildfires at the beginning stages in forest and wilderness areas, utilizing deep learning-based computer vision algorithms that control and then mitigate massive damages to human life and forest management.…”
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16030
Evaluation of the C-reactive protein serum levels in periodontitis patients with or without atherosclerosis – A clinical study
Published 2025-01-01“…Background: Periodontitis is a bacterial infection that can originate in the gums and progress to damage the bone and other structures supporting the teeth. …”
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16031
Lower circulating mitochondrial DNA and increased mitokines suggest significant mitochondrial dysfunction in systemic lupus erythematosus with renal involvement
Published 2025-02-01“…Mitokine levels, on the other hand, correlated with disease activity, in particular GDF-15 even after adjusting for renal involvement.Conclusion Our findings suggest that lower whole blood mtDNA/nucDNA ratio, a surrogate marker for mitochondrial dysfunction, reflects renal damage, while GDF-15 may also reflect disease activity in SLE. …”
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16032
Clinical manifestations in Egyptian Pompe disease patients: Molecular variability and enzyme replacement therapy (ERT) outcomes
Published 2025-01-01“…This underscores that delayed diagnosis and ERT can lead to irreversible heart damage from autophagy buildup. Conclusion Pompe disease has various clinical presentations and results in significant CMR findings, which can be attributed to different genetic mutations. …”
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16033
The role of chemical amendments on modulating ammonia loss and quality parameters of coâcomposts from waste cocoa pods
Published 2024-01-01“…Further, amended compost products were assessed for quality and possible phytotoxicity in a pot experiment. Method Pod borer damaged cocoa pods were co-composted in lab-scale vessels under ambient conditions with double superphosphate, phosphoric acid, and gypsum at 2%, 5% and 1% of fresh weight, respectively. …”
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16034
Pathologically altered articular cartilage attracts intense chondrocyte invasion into the extracellular matrix: in vitro pilot study
Published 2024-12-01“…Conclusions Our preliminary results showed that human nasal chondrocytes are capable of infiltrating the pathologically altered extracellular matrix of articular cartilage damaged by arthritis, thereby promoting its repair to a physiologically relevant state. …”
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16035
Institutional role of the prosecutor's office in preventing and combating corruption in the National Anti-Corruption Bureau of Ukraine: delimitation of powers and ways to improve t...
Published 2021-12-01“…As a result of the study, it has been concluded that the prosecutor's office, depending on the content of their tasks and functions, are involved in preventing and combating corruption in NABU in different ways, and the content of such activities is clearly dualistic, namely: on the one hand, the SAP in preventing compliance with the law during operational and investigative activities and pre-trial investigation of criminal offenses NABU can prevent or stop possible corruption by NABU employees; on the other hand, the prosecutor's office, if a corruption criminal offense is committed by a NABU official, must, in particular, ensure compliance with the law on the inevitability of liability for a criminal offense, within the competence to compensate for damages caused by such criminal offenses. The powers of the prosecutor's office to prevent and combat corruption in NABU have been grouped: representative, supervisory, security and law enforcement. …”
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16036
THE COURSE OF ACUTE RESPIRATORY COVID-19 DISEASE, COMPLICATED BY COMMUNITY-ACQUIRED PNEUMONIA AGAINST THE BACKGROUND OF THE CARDIOVASCULAR SYSTEM PATHOLOGY
Published 2021-08-01“…We conducted general clinical methods of research, determined the SARS-CoV-2 virus RNA by PCR and chest X-ray in 2 projections or computed tomography (CT) to identify the features of the lung tissue damage. Among the cardiovascular pathology (35%) we observed coronary heart disease: stable angina pectoris FC (functional class) II-III - 85%, postinfarction cardiosclerosis - 30%, hypertension - 65%. …”
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16037
Proteomic characterization of molecular mechanisms of paraquat-induced lung injury in a mouse model
Published 2025-01-01“…Conclusions PQ-induced ALI depends on over-activation of immune responses by damaged alveolar/endothelial cells, and the complement/coagulation cascade pathway plays a key role during this process. …”
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16038
Sex-based disparities in the association between uric acid levels and anxiety: a cross-sectional analysis of nationwide data in Korea
Published 2025-01-01“…Despite reports of increased oxidative damage and decreased antioxidants in anxiety disorders, findings remain inconclusive. …”
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16039
Neurapraxia following neck lifting procedures–anatomical consideration, contributing factors, and management strategies: a case report
Published 2024-12-01“…Adopting techniques such as working within the sub-platysma plane and using up to 0.4 mm diameter threads with blunt cannulas may help mitigate the risk of nerve damage. This report highlights the need for meticulous surgical practice and ongoing professional development to ensure the safety and efficacy of thread-lift procedures.…”
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16040
Les laboratoires de l’espace-temps mondialisé : le science-fictionnel et les expositions universelles de 1851 à 1939
Published 2016-06-01“…Ces modèles préfiguraient les flux de capitaux sans frontières rêvés par certaines versions de la théorie de la mondialisation d’alors. Cette essence science-fictionnelle non seulement réside dans le spectacle futuriste du « progrès » techno-scientifique, qui devint un modèle omniprésent dans les expositions universelles, mais aussi s’exprime par la spatialisation de l’histoire vue comme un développement. …”
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