Influence of Mesalazine on Ferroptosis-Related Gene Expression in In Vitro Colorectal Cancer Culture by Joanna Słoka, Barbara Strzałka-Mrozik, Sebastian Kubica, Ilona Nowak, Celina Kruszniewska-Rajs

“…Ferroptosis is characterized by iron imbalance and the accumulation of lipid peroxides and reactive oxygen species (ROS), leading to cellular damage and death. Thus, the discovery of safe inducers of ferroptosis, offering new hope in the struggle against CRC, remains crucial. …”
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Effects of Aerobic Exercise on Leukocyte-Mediated Liver Destruction in a Rat Model of Metabolic Syndrome by Fatmanur Er, Leyla Çimen, Ceren Suveren, Canan Yılmaz, Nurten Türközkan

“…Exercise not only reduces the known risk factors of the disease, but also protects the liver while preventing oxidative and nitrosative damage caused by the MPO-H2O2 system in the liver, which increases with the effect of fructose and is necessary for the formation of non-alcoholic fatty liver disease.…”
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Comparative transcriptome analysis reveals the key role of photosynthetic traits in the formation of differences in photothermal sensitivity in tobacco by Yanfeng Zheng, Qiwei Yu, Anbin Lu, Xiue Chen, Kai Yang, Jingyao Zhang, Ying Huang, Renxiang Liu

“…However, this promotion also led to the increased production of harmful substances such as hydrogen peroxide and superoxide radicals, which can damage cellular structure and function. In the flavonoid biosynthesis pathway, genes such as FLS, CHI, and PAL were significantly upregulated, which enhanced the plant’s antioxidant capacity. …”
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Artesunate Restrains Maturation of Dendritic Cells and Ameliorates Heart Transplantation-Induced Acute Rejection in Mice through the PERK/ATF4/CHOP Signaling Pathway by Yuanyang Chen, Sihao Zheng, Zhiwei Wang, Xin Cai, Yanjia Che, Qi Wu, Shun Yuan, Xiaohan Zhong

“…Furthermore, the treatment alleviated the oxidative stress damage of BMDCs. Conclusion. ART can inhibit maturation of dendritic cells through the endoplasmic reticulum stress signaling pathway, thereby alleviating acute rejection in mice after heart transplantation.…”
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CHARACTERISTICS OF THE COURSE OF LEUCOCYTOCLASTIC VASCULITIS WITH SKIN LESIONS. ANALYSIS OF CLINICAL CASES by O.A. Borzykh, O.V. Belan, I.A. Mormol, Y.M. Avramenko, T. Іengalychev, T.M. Markina

“…Leukocytoclastic vasculitis of the skin (LCV) is an isolated cutaneous vasculitis without damage to internal organs. At present, vasculitis is considered a polyetiological disease. …”
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Structuring the genetic collection of sunflower by V. A. Gavrilova, I. N. Anisimova, N. V. Alpatieva, E. A. Porokhovinova

“…A set of 237 sunflower lines from VIR’s genetic collection was phenotyped for their morphological characters (plant height; branching type; shapes and sizes of the leaf, petiole, flower head, disk and ray florets; downy mildew damage rate) and genotyped with molecular markers. …”
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SCREENING OF THE CUCUMBER COLLECTION FOR RESISTANCE TO DOWNY MILDEW IN THE LOWER VOLGA REGION by E. H. Sukhanberdina, A. A. Grushin, T. M. Piskunova

“…During the years of study, 23 accessions, previously resistant to downy mildew, lost their resistance and suffered severe damage from the disease. Hence, it seems obvious that resistant accessions should be periodically retested for susceptibility to downy mildew. …”
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Mapping ground deformation in the northern Yangtze River estuary using improved MT-InSAR based on ICA and non-stationary analysis by Zhijie Zhang, Songbo Wu, Guoqiang Shi, Xiaoli Ding, Chaoying Zhao, Bochen Zhang, Liang Chen, Zhong Lu

“…Coastal regions are increasingly vulnerable to ground deformation hazards, which can cause structural damage and amplify flood risks. Accurately monitoring the evolution of such deformation is crucial for hazard assessment. …”
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Protective effect of silencing lncRNA HCP5 against brain injury after intracerebral hemorrhage by targeting miR-195-5p by Zhanhua Lu, Kun Huang

“…Abstract Background Intracerebral hemorrhage (ICH) is a common subtype of stroke, characterized by a high mortality rate and a tendency to cause neurological damage. This study aims to investigate the role and mechanisms of lncRNA HCP5 in ICH. …”
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ABIOTIC STRESSORS AND THEIR EFFECT ON THE ACCUMULATION OF ASSIMILATES BY PLANTS AND THE YIELD OF VEGETABLE PEA by O. V. Putina, A. G. Besedin

“…., are spontaneous, and their impact causes significant damage to plants. This is also true for the common and leafless morphotypes of vegetable pea, which are most widely used in large-scale crop production.Objectives. …”
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An Aloe-Based Composition Constituting Polysaccharides and Polyphenols Protected Mice against D-Galactose-Induced Immunosenescence by Mesfin Yimam, Teresa Horm, Alexandria O’Neal, Ping Jiao, Mei Hong, Qi Jia

“…UP360 was found to improve the immune response as evidenced by stimulation of innate and adaptive immune responses, increase antioxidant capacity as reflected by augmented SOD and Nrf2, and preserve vital immune organs, such as the thymus, from aging-associated damage. The findings depicted in this report show the effect of the composition in activating and maintaining homeostasis of the immune system both during active infections and as a preventive measure to help prime the immune system. …”
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Influence of indole acetic acid, arginine and mango fruit waste biochar on nutrients, chlorophyll contents and antioxidants of Fenugreek in salt affected soil by Misbah Hareem, Sammina Mahmood, Subhan Danish, Rana Khalid Iqbal, Abdullah A. Alarfaj, Sulaiman Ali Alharbi

“…L-arginine, an amino acid, is crucial for plant defense mechanisms, forming proline, polyamines, and nitric oxide, which regulate biological activities and prevent oxidative damage. Mango fruit waste biochar enhances soil fertility and water retention, thereby enhancing fruit development and yield. …”
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Ultrastructural studies distinguish skin diversities among Galápagos iguanas by Manuel Scimeca, Rita Bonfiglio, Giuliano Colosimo, Eleonora Candi, Glenn P. Gerber, Gregory A. Lewbart, Alessandro Mauriello, Gerry Melino, Christian Sevilla, Yufang Shi, Ying Wang, Gabriele Gentile

“…These skin characteristics may reduce the penetration power of UV rays into the superficial loose dermis, thereby attenuating potential UV-related damage such as DNA breaks and ROS generation. These findings offer insights into the adaptive strategies of these iguanas.…”
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ρ-Coumaric acid-zinc oxide nanoparticles improve post-thaw quality of goat spermatozoa and developmental competence of fertilized oocytes in vitro by Bahareh Akhtarshenas, Rasoul Kowsar, Mehdi Hajian, Nima Tanhaei Vash, Leila Soltani, Amir Hossein Mahdavi, Mohammad Hossein Nasr Esfahani

“…Moreover, using ρ-CA-ZnONPs significantly decreased lipid peroxidation and DNA damage compared with the other treatments. In conclusion, spermatozoa are cryotolerant, resistant to post-thaw conditions, and have fertilizing ability that can be increased by adding ρ-CA-ZnONPs as an antioxidant to goat semen extenders.…”
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A novel hybrid cooling system for a Lithium-ion battery pack based on forced air and fins integrated with phase change material by Mohanad F. Hassan, Abdul Hadi N. Khalifa, Ahmed J. Hamad

“…However, they face challenges, including thermal runaway and safety risks from thermal damage to an explosion. Therefore, effective cooling methods and strong thermal management systems ensure their safety and optimal performance. …”
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High-Affinity Anti-VISTA Antibody Protects against Sepsis by Inhibition of T Lymphocyte Apoptosis and Suppression of the Inflammatory Response by Tianzhu Tao, Lulong Bo, Teng Li, Longbao Shi, Hui Zhang, Bo Ye, Yuhai Xu, Qingqing Ma, Xiaoming Deng, Guorong Zhang

“…The effects of anti-VISTA mAb on the 7-day survival, lymphocyte apoptosis, cytokine expression, bacterial burden, and vital organ damage were determined. Furthermore, the effects of anti-VISTA mAb on CD3+ T cell apoptosis and macrophage activation were determined in vitro. …”
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Design, Synthesis, and Pharmacological Screening of Novel Porphyrin Derivatives by Ahmed A. Fadda, Rasha E. El-Mekawy, Ahmed El-Shafei, Harold S. Freeman, David Hinks, Manal El-Fedawy

“…These dyes were used as a model to study the free radical-induced damage of biological membranes and the protective effects of these porphyrins. …”
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Study on Interaction Mechanism of Natural Gas Pipe-Landslide System Reinforced by Micropile Groups Based on Model Test by Wei Guan, Honggang Wu, Daoyong Wu, Lin Tang, Hong Wei

“…The screw micropile cannot effectively resist the landslide thrust at a large load level, so the risk of pipeline damage is greater. The yield strength and ultimate strength of the perforated pipe micropile are greater than those of the screw micropile, and the perforated pipe micropile can still exert a certain residual resistance after reaching the ultimate bearing capacity, which has a beneficial effect on the reinforcement of the pipeline crossing the landslide system. …”
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Melatonin Enhances Maize Germination, Growth, and Salt Tolerance by Regulating Reactive Oxygen Species Accumulation and Antioxidant Systems by Wei-Qing Li, Jia-Yu Li, Shao-Jie Bi, Jia-Yue Jin, Zhong-Ling Fan, Zi-Lin Shang, Yi-Fei Zhang, Yan-Jie Wang

“…Moreover, exogenous melatonin alleviated NaCl-induced membrane damage and oxidative stress, and reduced Na⁺ content and excessively large quantities of reactive oxygen species (ROS). …”
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Modulation of the thiol redox proteome by sugarcane ash-derived silica nanoparticles: insights into chronic kidney disease of unknown etiology by Arthur D. Stem, Cole R. Michel, Peter S. Harris, Keegan L. Rogers, Matthew Gibb, Carlos A. Roncal-Jimenez, Richard Reisdorph, Richard J. Johnson, James R. Roede, Kristofer S. Fritz, Jared M. Brown

“…SiNPs have high potential for generation of reactive oxygen species (ROS), and their accumulation in kidney could result in oxidative stress induced kidney damage consistent with CKDu pathology. Methods In order to characterize the impact of sugarcane ash derived (SAD) SiNPs on human kidney proximal convoluted tubule (PCT) cells and identify potential mechanisms of toxicity, HK-2 cells were exposed to treatments of either pristine, manufactured, 200 nm SiNPs or SAD SiNPs and changes to cellular energy metabolism and redox state were determined. …”
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