RETRACTED ARTICLE: P16INK4a Deletion Ameliorated Renal Tubulointerstitial Injury in a Stress-induced Premature Senescence Model of Bmi-1 Deficiency by Jianliang Jin, Jianguo Tao, Xin Gu, Zhenzhen Yu, Rong Wang, Guoping Zuo, Qing Li, Xianhui Lv, Dengshun Miao

“…Our results demonstrated that p16INK4a deletion largely rescued renal aging phenotypes caused by Bmi-1 deficiency, including impaired renal structure and function, decreased proliferation, increased apoptosis, senescence and SASP, DNA damage, NF-κB and TGF-β1/Smad signal activation, inflammatory cell infiltration, and tubulointerstitial fibrosis and tubular atrophy. …”
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Multi-omics analyses identify gut microbiota-fecal metabolites-brain-cognition pathways in the Alzheimer’s disease continuum by Han Zhao, Xia Zhou, Yu Song, Wenming Zhao, Zhongwu Sun, Jiajia Zhu, Yongqiang Yu

“…We also observed progressive gray matter atrophy in broadly distributed gray matter regions and gradual micro-structural integrity damage in widespread white matter tracts along the AD continuum. …”
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Association of polymorphism <i>TP53</i> Arg72Pro with radon-induced lung cancer in the Kazakh population by O. Bulgakova, A. Kussainova, A. Kakabayev, А. Kausbekova, R. Bersimbaev

“…The tumor suppressor gene TP53 is a key mediator of the DNA damage response cascade following cell exposure to ionizing radiation. …”
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A GIS-based Study of Wild Atlantic Way in the West of Ireland: Its Associated Organisations and Environmental impacts. by Leanne Leonard

“…The West of Ireland is home to a range of areas protected by the Birds and Habitats Directives which aim to safeguard against potentially damaging developments, meaning the anthropogenic effects from tourists must be carefully managed to ensure the sustainability of the region and continued success of this large-scale branding exercise. …”
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A De Novo Mutation in ACTC1 and a TTN Variant Linked to a Severe Sporadic Infant Dilated Cardiomyopathy Case by Jose G. Acuña-Ochoa, Norma A. Balderrábano-Saucedo, Ana C. Cepeda-Nieto, Maria Y. Alvarado-Cervantes, Vianca L. Ibarra-Garcia, Daniel Barr, Matthew J. Gage, Ryan Pfeiffer, Dan Hu, Hector Barajas-Martinez

“…Computational 3D modeling of the mutated proteins showed electrostatic and conformational shifts of cardiac actin compared to wild-type version, as well as changes in the stability of the compact/folded states of titin that normally contributes to avoid mechanic damage. In conclusion, our findings suggest a likely pathogenic de novo mutation in ACTC1 in coexpression of a TTN variant as possible causes of an early onset of a severe DCM and premature death. …”
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Effects of Mulch Type, Plant Cultivar, and Insecticide Use on Sweet Potato Whitefly Population in Chili Pepper by Andi Nasruddin, Nurariaty Agus, Alam Saubil, Jumardi Jumardi, Burhanuddin Rasyid, Andry Siriniang, Andi Dirham Nasruddin, Firdaus Firdaus, Ahwiyah Ekawaty Said

“…It sucks plant sap, emits honeydew on which sooty mold fungi grow, and transmits the pepper yellow leaf curl Indonesia virus (PepYLCIV), the most damaging viral disease of chili in Indonesia. Farmers rely mainly on insecticide to control the insect with two to three sprays in a week. …”
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Study on the Tribological Behavior of Laser Surface Texturing on Silicon Nitride Ceramic Under Water Lubrication by Hong-Jian Wang, Jing-De Huang, Bo Wang, Yang Zhang, Jin Wang

“…In contrast, better surface wettability played a more important role in reducing the COF at higher reciprocating frequencies. The most severe damage observed on the untextured Si₃N₄ ceramic led to a higher wear rate. …”
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Peroxiredoxin 6 maintains mitochondrial homeostasis and promotes tumor progression through ROS/JNK/p38 MAPK signaling pathway in multiple myeloma by Dandan Gao, Yang Lv, Fei Hong, Dong Wu, Ting Wang, Gongzhizi Gao, Zujie Lin, Ruoyu Yang, Jinsong Hu, Aili He, Pengyu Zhang

“…Collectively, PRDX6 protects MM cells from oxidative damage and maintains mitochondrial homeostasis. And targeting PRDX6 is an attractive strategy to enhance the anti-tumor effect of bortezomib in MM.…”
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Chronic prostatitis/chronic pelvic pain syndrome induces metabolomic changes in expressed prostatic secretions and plasma by Fang-Xing Zhang, Xi Chen, De-Cao Niu, Lang Cheng, Cai-Sheng Huang, Ming Liao, Yu Xue, Xiao-Lei Shi, Zeng-Nan Mo

“…Overall, metabolomic alterations in the EPS and plasma of patients were primarily associated with oxidative damage, energy metabolism abnormalities, neurological impairment, and immune dysregulation. …”
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The implication of leaf anatomical structure for the selective breeding of lilacs by L. M. Pshennikova

“…The cultivars of the common lilac (Syringa vulgaris) grown in the south of the Russian Far East are not always winter-hardy and are often damaged by fungal diseases due to a very humid climate. …”
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Features of dry eye syndrome treatment by E.A. Egorov

“…Egorov<br> Pirogov Russian National Research Medical University, Moscow, Russian Federation<br> <br> <b>Abstract</b><br> Dry eye syndrome (DES) is a multifactorial disease of eye surface, characterized by a disturbance of tear film homeostasis and accompanied by ophthalmologic symptoms, in development of which an etiological role is played by a disturbance of stability, hyperosmolarity of the tear film, inflammation and damage to the eye surface, and neurosensory changes. …”
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The control effect and induced disease resistance mechanism of Bacillus tequilensis on wheat powdery mildew by Qiuyan Bi, Fen Lu, Jie Wu, Xiangyu Liu, Xiuying Han, Jianjiang Zhao

“…Tritici causes wheat powdery mildew (WPM) and severe wheat damage worldwide. To prevent WPM and emerging chemical fungicide resistance, researchers investigated the control effectiveness and induced disease resistance mechanisms of the biocontrol agent Bacillus tequilensis. …”
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Strength Characteristics of Nonpenetrating Joint Rock Mass under Different Shear Conditions by Qingzhi Chen, Yuanming Liu, Shaoyun Pu

“…The main conclusions are as follows: (1) the strength of rock mass would increase with the increase of confining pressure for those rock specimens with same degrees of shear after the direct shear test; (2) for rock specimens with different degrees of shear after the direct shear test, if the shearing degree of the rock specimen was greater, the strength of the rock specimen would be lower in the triaxial test; (3) for rock specimens with the same damage degree after direct shear test, the greater the normal stress in direct shear test is, the smaller the peak axial pressure would be in the triaxial test; (4) if the specimen was sheared under higher normal stress in direct shear test, the cohesion of it would be lower and the internal friction angle would be larger. …”
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Deep CNN ResNet-18 based model with attention and transfer learning for Alzheimer's disease detection by Sofia Biju Francis, Sofia Biju Francis, Jai Prakash Verma

“…Alzheimer's disease leads to a rapid and irreversible decline in cognitive abilities by damaging memory cells.MethodsA ResNet-18-based system is proposed, integrating Depth Convolution with a Squeeze and Excitation (SE) block to minimize tuning parameters. …”
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Research on Business Environment Risk Governance Based on Occupational Claims: 1784 Cases of Food Safety Disputes by Jiangjie Sun, Yufei Gao, Xueli Jiang, Yan Li, Mengyao Yang, Ziyan Zhao, Hangzhou Yang, Jinliang You

“…The results show that occupational claims are being reexamined by society; the continued rise in the number of unsuccessful occupational claims cases indicates a lack of regulatory guidance for their profit-making behavior, the existence of malicious reporting complaints against business behavior, damage to the business environment, and a certain lack of legality. …”
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The Evaluation of Diagnostic Role of Cardiac Troponin T (cTnT) in Newborns with Heart Defects by Agata Tarkowska, Wanda Furmaga-Jablonska

“…To evaluate diagnostic usefulness of cTnT in correlation with other markers of circulatory failure and myocardial damage in newborns with heart defects. Patients and Methods. …”
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Basic research for ultrasound-guided injection into skeletal muscle lesions in an experimental animal model by KiyomitsuFujimoto, TakashiKanamoto, ShunyaOtani, RyoMiyazaki, KosukeEbina, KenNakata

“…Results: Evaluation of short-axis ultrasound images and cross-sectional histological staining showed a strong correlation (r = 0.927; p < 0.001) between the maximum muscle damage area in ultrasound and haematoxylin and eosin (H&E) staining evaluations. …”
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Forecasting GOES 15 >2 MeV Electron Fluxes From Solar Wind Data and Geomagnetic Indices by C. Forsyth, C. E. J. Watt, M. K. Mooney, I. J. Rae, S. D. Walton, R. B. Horne

“…Abstract The flux of > 2 MeV electrons at geosynchronous orbit is used by space weather forecasters as a key indicator of enhanced risk of damage to spacecraft in low, medium, or geosynchronous Earth orbits. …”
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Investigation of the efficacy of tyrosol on doxorubicin-induced acute cardiotoxicity in rats by Mustafa Cellat, Muhammed Etyemez

“…Because of the reduction in oxidative damage in the heart, the serum creatine kinase MB and creatine kinase activity decreased dramatically (p<0.05). …”
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Identifying RBBP7 as a Promising Diagnostic Biomarker for BK Virus-Associated Nephropathy by Yicun Wang, Yuxuan Wang, Di Zhang, Hao Zhang, Wei Wang, Xiaopeng Hu

“…We collected gene expression profiles of 169 kidney biopsies taken from BKVN, rejection, and stable functioning allografts, based on single sample gene set enrichment analysis and random forest algorithm, and three hallmark activities associated with DNA damage and proliferation were found to be relatively specific in BKVN. …”
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