Knockout of the ING5 epigenetic regulator confirms roles in stem cell maintenance and tumor suppression in vivo. by Buthaina Al Shueili, Arthur Dantas, Etienne Mahe, Tak Ho Chu, Yang Yang, Elodie Labit, Eren Kutluberk, Nicolas Lasaleta, Anand Masson, Hiba Omairi, Kenichi Ito, Roman J Krawetz, Rajiv Midha, Gregory Cairncross, Karl Riabowol

“…ING5 KO mouse embryo fibroblasts accumulate in G2 of the cell cycle, have high levels of abnormal nuclei and show high basal levels of the γH2AX indicator of DNA damage. KO animals also develop severe dermatitis at a 5-fold higher rate that wild-type littermates. …”
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Enhanced Stability of Gr, h-BN and Gr/h-BN protected MoS2 flakes under laser illumination by Chak-Ming Liu, Sheng-Yu Hsu, Hsin-Sung Chen, Chuan-Che Hsu, Yann-Wen Lan, Hsiang-Chih Chiu, Wen-Chin Lin

“…The optical excitation and applications of molybdenum disulfide (MoS₂) is critical due to its limited thickness and susceptibility to damage from high-intensity laser illumination, which can cause significant local heating and structural degradation. …”
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Collapsing Pattern Class-IV Lupus Nephritis Presenting as Posterior Reversible Encephalopathy Syndrome and Cardiac Tamponade: A Rare COVID-19 Sequelae by K Harshitha Reddy, Pranjal Kashiv, Sunil Kumar, Sourya Acharya, Kapil Navin Sejpal

“…The collapsing variety of FSGS (cFSGS) is defined histopathologically by segmental or global glomerular capillary condensation and obliteration, the appearance of hyperplastic and hypertrophic podocytes, and substantial tubulointerstitial damage. Numerous aetiologies have been proposed, including viral infections such as Human Immunodeficiency Virus (HIV), Cytomegalovirus (CMV), Epstein-Barr virus, and Parvovirus B19, as well as medications and acute ischaemia. …”
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Essence, purpose and objectives of pre-trial investigation: theoretical and legal characteristics by V. V. Matus, V. V. Ablamska

“…This involves identifying a range of potential suspects and conducting interrogations with them to establish their involvement in the crime; evaluating evidence, establishing its reliability and relevance to the case; making decisions on serving a notice of suspicion and referring the proceedings to court; making decisions on continuing the pre-trial investigation or terminating it; restoring the rights, freedoms and legitimate interests of the victim, compensating for the damage caused, etc.…”
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Optimization of Starch Saccharification Process and Structural Characterization of Starch Using Low Transglycosidation Activity Glucoamylase GluM3 by Haiyue FAN, Zhao YU, Zhengjie ZHANG, Ming LI, Yingguo BAI, Feng YU, Zhongyuan LI

“…There was a certain degree of damage to internal crystalline structure during saccharification. …”
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Age-Dependent Loss of Mitochondrial Function in Epithelial Tissue Can Be Reversed by Coenzyme Q10 by Daniel Schniertshauer, Daniel Gebhard, Jörg Bergemann

“…The accumulation of reactive oxygen species damaged mitochondrial DNA and proteins can induce mitochondrial dysfunction within the electron transport chain. …”
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Intergranular creep resistance affected by grain boundary carbides to suppress lamellae γʹ precipitation in a specially designed inconel 740H variant by Cheol-Hyeok Yang, Chiwon Kim, Siyeon Kim, Hi-Won Jeong, Hyungsoo Lee, Dae Won Yun, Hyun-Uk Hong

“…The higher fraction of grain boundary carbides in the SAG sample effectively suppressed nodule-like γʹ formation and reduced creep damage by strengthening the grain boundaries, preventing dislocation impingement. …”
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Rheumatoid Arthritis Effects on Kidney and Liver and their Correlations with CDAI by Tamara Salman Mohammed, Raya Ezat Maroof, Ali Hussein Al-Hafidh

“… Rheumatoid arthritis (RA) is a disease characterized by chronic autoimmune inflammation of body joints, causing movement disability, loss of functions, joint damage, and many complications. Persistent usage of anti-rheumatic drugs has several side effects, which may cause heart, kidney, or liver diseases. …”
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The Active Compound Thymoquinone Alters Chondrogenic Differentiation of Human Mesenchymal Stem Cells via Modulation of Intracellular Signaling by Banu ISKENDER

“…The increase in proinflammatory cytokines in cartilage damage can increase the expression of apoptotic and proinflammatory genes and the matrix degradation enzymes via nuclear factor-κB (NF-κB). …”
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Simulation of Load–Sinkage Relationship and Parameter Inversion of Snow Based on Coupled Eulerian–Lagrangian Method by Ming Zhu, Pengyu Li, Dongqing Li, Wei Wei, Jianfeng Liu, Xixing Long, Qingkai Meng, Yongjie Shu, Qingdong Yan

“…In this paper, an innovative parameter inversion method based on in situ test results is proposed to calibrate the snow parameters, which avoids the damage to the mechanical properties of snow when making test samples using traditional test methods. …”
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Infusion therapy for chronic liver diseases by I. A. Kurkina, M. V. Mayevskaya, I. N. Tikhonov, V. N. Zozulya, V. I. Leschenko

“…Succinic acid is presumed to act as the paracrine agent produced by damage hepatocytes (e.g. at ischemia), affecting pericytes (Ito's cell) in the liver through SUCNR1receptors. …”
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DESIGN AND RESEARCH ON MODULAR CUTTERHEAD AND MAIN DRIVE OF VARIABLE MEASUREMENT RECTANGLE PIPE JACKING MACHINE by ZHANG HaoWen, LUO HongMei, ZHENG Jun, GUO Tao, WANG YuChen

“…The results show that: in the construction of soft soil layer, the maximum stress of the cutterhead is 229.7 MPa, which is lower than the yield strength of the material, the safety factor is 1.55, the inherent frequency of the cutterhead at the first six orders range from 179.3 Hz to 196.5 Hz; the maximum stress of the crankshaft is 491.4 MPa, which is located at the front spindle at the neck fillet, the safety factor is 1.89, and the inherent frequency of the crankshaft at the first six orders range from 333.4 Hz to 1 304.5 Hz. The main fatigue damage points of the crankshaft are concentrated at the fillet of the front main journal, the minimum number of cycles is 3.37×10~7, and the theoretical life is 165 928 h. …”
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Sequential Defense Strategies: From Ant Recruitment to Leaf Toughness by Danilo F. B. dos Santos, Eduardo S. Calixto, Helena M. Torezan-Silingardi, Kleber Del-Claro

“…Plants express many types of defenses in response to herbivory damage. These defenses can be displayed as a sequence or they can overlap, increasing efficiency in protection. …”
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An Adverse Outcome Pathway Linking Organohalogen Exposure to Mitochondrial Disease by Brooke McMinn, Alicia L. Duval, Christie M. Sayes

“…Adverse outcome pathways (AOPs) are pragmatic tools in human health hazard characterization and risk assessment. …”
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Modern approach to infusion therapy of pregnant women with gestational hypertension by O.V. Vaskiv, A.P. Grigorenko, O.G. Gorbatyuk, A.S. Shatkovska, A.M. Binkovska, I.A. Priymak

“…The data of our study show that in patients receiving the proposed infusion therapy there was a significant decrease in the development of placental dysfunction by 38.3%, the threat of premature birth – by 18.3% and fetal distress – by 30.0%, premature rupture of the membranes – by 35.0%, weakness of labor – by 28.3%, a decrease in the risk of perinatal central nervous system damage – by 33.3% and the frequency of cephalohematomas – by 30.0% compared with women who received only antihypertensive therapy.…”
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THE DETERMINATION OF THE KIND OF PHASE-TO-PHASE SHORT CIRCUIT IN CURRENT LINE PROTECTION OF 6–35 KV by F. A. Romaniuk, O. A. Huryanchyk, M. A. Shevaldin, V. S. Kachenya

“…Preference is given to the method of determining damages according to the relative unbalance the operating currents. …”
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Insecticidal Activity and Chemical Composition of the Morinda lucida Essential Oil against Pulse Beetle Callosobruchus maculatus by Moses S. Owolabi, Eduardo Padilla-Camberos, Akintayo L. Ogundajo, Isiaka A. Ogunwande, Guido Flamini, Olaniyi K. Yusuff, Kirk Allen, Karen Isabel Flores-Fernandez, Jose Miguel Flores-Fernandez

“…Insecticidal activity of essential oil extracted from Morinda lucida was tested on pulse beetle Callosobruchus maculatus, which is a pest that causes serious damage to several pulses. The insecticidal activity was compared with two pesticides, Phostoxin and Primo-ban-20. 120 mixed sex adult C. maculatus were introduced, along with 30 g of cowpeas. …”
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Assessment of the Effectiveness of Fascial Manipulation in Patients with Degenerative Disc Disease of the Lumbosacral Spine by Anna Mikołajczyk-Kocięcka, Marek Kocięcki, Lech Cyryłowski, Aleksandra Szylińska, Paweł Rynio, Magdalena Gębska, Ewelina Szuba, Jarosław Kaźmierczak

“…<b>Material and Methods:</b> This study included 69 patients with intervertebral disc damage of the lumbar spine, as confirmed by magnetic resonance imaging. …”
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Therapeutic Implications of a Polymethoxylated Flavone, Tangeretin, in the Management of Cancer via Modulation of Different Molecular Pathways by El-Shaimaa A. Arafa, Noura T. Shurrab, Manal A. Buabeid

“…Using tangeretin in combination with clinically applied anticancer drugs could be a good strategy for increasing the efficiency of these agents and protecting noncancerous cells from damage caused by chemotherapy. The purpose of this review is to highlight the protective effects of a novel natural product, tangeretin against chemotherapeutic-induced toxicity. …”
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Correlation between cognitive status and tomographic findings in patients with neurocysticercosis. Ecuador, 2019 – 2020 by Jorge Luis Anaya González, Francisco López-Muñoz, Erlen Carmona Alvarez-Builla, Adriana Edit Miniet Castillo

“…<p><strong>Background</strong>: Many patients with neurocysticercosis manifest cognitive damage, with important effects on their quality of life.…”
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