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15641
EFFECTS OF GREEN TEA EXTRACT ON GRAAFIAN FOLLICLES AND SERUM17b-ESTRADIOL IN MONOSODIUM GLUTAMATE-EXPOSED RATS
Published 2024-10-01“…MSG administration in rats has been reported to induce oxidative stress causing damage to ovarian histological structures by affecting number of follicles and production of reproductive hormones. …”
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15642
Anti-Inflammatory Effects of Concentrated Ethanol Extracts of Edelweiss (Leontopodium alpinum Cass.) Callus Cultures towards Human Keratinocytes and Endothelial Cells
Published 2012-01-01“…ECC55 (10–50 μg/mL) protected PHK from solar UV-driven damage, by enhancing early intracellular levels of nitric oxide, although not affecting UV-induced expression of inflammatory genes. …”
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15643
Effect of Shogaol on the Expression of Intestinal Stem Cell Markers in Experimentally Induced Colitis in BALB/c Mice
Published 2019-01-01“…Shogaol showed a better curative effect than did 6-TG in repairing the colonic mucosal damages in DSS-exposed mice as indicated by the levels of CD133 and CD34 expression in the colonic crypts and by the DAI score, colon length measurements, & histological index score which were significantly reduced in mice treated by Shogaol, particularly the 20 and 40 mg/kg BW doses. …”
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15644
Features of Modeling the Operating Modes of Outdoor Lighting Lines
Published 2022-12-01“…Additional possibilities for modeling the modes of operation of lighting lines are to search for damage (detection of short circuits, determination of the presence of faulty lamps).…”
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15645
From gut to liver: Exploring the crosstalk between gut-liver axis and oxidative stress in metabolic dysfunction-associated steatotic liver disease
Published 2025-01-01“…Our analysis reveals several key findings: (1) Bile acid dysregulation can trigger oxidative stress through enhanced ROS production in hepatocytes and Kupffer cells, leading to mitochondrial dysfunction and lipid peroxidation; (2) Gut microbiota dysbiosis disrupts intestinal barrier function, allowing increased translocation of endotoxins like LPS, which activate inflammatory pathways through TLR4 signaling and promote oxidative stress via NADPH oxidase activation; (3) The redox-sensitive transcription factors NF-κB and Nrf2 serve as crucial mediators in the gut-liver axis, with NF-κB regulating inflammatory responses and Nrf2 orchestrating antioxidant defenses; (4) Oxidative stress-induced damage to intestinal barrier function creates a destructive feedback loop, further exacerbating liver inflammation and disease progression. …”
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15646
Nano-curcumin Effects on Ischemic Stroke clinical outcomes and Interleukin-6 Levels: Pilot Randomized Clinical Trial
Published 2025-01-01“…Background: Accumulation of inflammatory factors in the stroke area results in brain tissue damage and a patient’s disability. It has been demonstrated that curcumin has neuroprotective effects. …”
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15647
Indomethacin-Induced Gastric Ulcer in Rats: Gastroprotectivity of <i>Muscari neglectum</i> in Water
Published 2024-12-01“…<b>Results:</b> The Gastric tissue examinations at biochemical, macroscopic and pathological levels showed that MN extracts effectively prevented indo-methacin-induced gastric mucosal damage. The 400 mg/kg dose exhibited the most effective antiulcer effect, with a 69% protective efficacy. …”
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15648
Renoprotective Effect of Pitavastatin against TAA-Induced Renal Injury: Involvement of the miR-93/PTEN/AKT/mTOR Pathway
Published 2024-01-01“…By altering the PTEN/AKT/mTOR pathway, pitavastatin may boost kidney antioxidant capacity and minimize oxidative damage. Statins have several benefits, including antioxidant and anti-inflammatory characteristics. …”
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15649
Disproportionate impacts of building materials production facilities on neighboring communities
Published 2025-01-01“…Based on this spatial understanding, we provide methods that can be implemented to support community engagement and mitigate damages to populations neighboring industrial materials manufacturing. …”
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15650
Estimating the Geoelectric Field and Electric Power Transmission Line Voltage During a Geomagnetic Storm in Alberta, Canada Using Measured Magnetotelluric Impedance Data: The Influ...
Published 2021-10-01“…Abstract Estimating the effect of geomagnetic disturbances on power grid infrastructure is an important problem since they can induce damaging currents in electric power transmission lines. …”
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15651
Purple Corn (Zea mays indurata) Ice Cream as an Immune Booster in The Pandemic Era
Published 2022-07-01“…One of the nutritional contents of purple corn was the flavonoid group in the form of anthocyanin compounds as a source of antioxidants to increase the body's immunity and prevent diseases caused by viruses, fungi, and bacteria, as well as prevent atherosclerosis, gastric damage, cholesterol, obesity, and others. Anthocyanin compounds in purple corn 70mg/100 grams. …”
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15652
Finding influential nodes in complex networks based on Kullback–Leibler model within the neighborhood
Published 2024-06-01“…Finally, it assesses the damage influence of the removed node by integrating the network attributes and KL divergence model, thus achieving the evaluation of node importance. …”
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15653
Efficacy of CLT4A variants as immunoregulatory molecules among Vitiligo patients in Saudi Arabia
Published 2025-02-01“…In vitiligo, cytotoxic T-lymphocytes damage melanocytes, causing skin depigmentation. The Cytotoxic T-Lymphocyte Antigen 4 (CTLA-4) gene has been reported to be related to vitiligo and other autoimmune diseases. …”
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15654
Purpurin suppresses Salmonella invasion of host cells by reducing the secretion of T3SS-1 effector proteins
Published 2025-02-01“…The results from animal experiments indicated that PPR exhibited significant efficacy in a mouse enteritis model caused by ST infection, increasing the survival rate of mice infected with a lethal dose by 50%, reducing spleen colonization in infected mice, and alleviating tissue damage resulting from ST infection. Therefore, PPR represents a promising antivirulence drug that targets the T3SS of ST and may serve as a hit compound for the development of novel antivirulence drugs for the treatment of ST.…”
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15655
Myeloma cell-derived CXCL7 facilitates proliferation of tumor cells and occurrence of osteolytic lesions through JAK/STAT3 pathway
Published 2025-02-01“…CXCL7 might be a crucial regulator of osteolytic damage in MM. Subsequently, the association between the expression level of CXCL7 and pathological fractures in patients was investigated, and the impact of CXCL7 on MM proliferation was confirmed both in vivo and in vitro. …”
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15656
The antibacterial activity of clove Syzygium aromaticum extract and its effects on the survival rate of hybrid grouper Epinephelus fuscoguttatus ♀ × E. lanceolatus ♂ infected with...
Published 2023-01-01“…The conclusion of this research is that clove extract has antibacterial activity that can inhibit growth and cause cell morphological damage to V. alginolyticus. The application of clove powder at a dose of 15g kg-1 was able to improve the survival value which was a higher post-challenge test. …”
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15657
Seismic Performance and Flexural Capacity Analysis of Embedded Steel Plate Composite Shear Wall Structure with Fiber-Reinforced Concrete in the Plastic Hinge Zone
Published 2025-01-01“…However, bending failure is prone to occur during strong earthquakes, and the single energy dissipation mechanism of the plastic hinge zone at the bottom leads to the concentration of local wall damage. To improve the embedded steel plate composite shear wall structure, the plastic hinge zone of the composite shear wall is replaced by fiber-reinforced concrete (FRC) and analyzed by ABAQUS finite element simulation analysis. …”
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15658
CO2-Driven Hydraulic Fracturing Trajectories across a Preexisting Fracture
Published 2021-01-01“…Defining the trajectory of hydraulic fractures crossing bedding planes and other fractures is a significant issue in determining the effectiveness of the stimulation. In this work, a damage evolution law is used to describe the initiation and propagation of the fracture. …”
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15659
Sjögren’s Syndrome: Concerted Triggering of Sicca Conditions
Published 2019-01-01“…Cytometric analysis of the blood cells revealed a dropping amount of circulating natural killers and dendritic cells in patients with SS. …”
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15660
Causal relationship between immune cells and risk of heart failure: evidence from a Mendelian randomization study
Published 2025-01-01“…BackgroundHeart failure (HF) is a clinical syndrome resulting from structural damage or dysfunction of the heart. Previous investigations have highlighted the critical involvement of immune cells in the progression of heart failure, with distinct roles attributed to different types of immune cells. …”
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