Pyrogallol acts as a novel anticancer factor to enhance the sensitivity to cisplatin in ovarian cancer cells through inducing miR-15a upregulation by Azin Shirani, Razieh Mirabbasi, Leila Shabani, Somayeh Reiisi

“…Cisplatin is known as an effective chemotherapeutic agent against cancer by inducing DNA damage and apoptosis. However, the effect of pyrogallol alone and in combination with cisplatin on proliferation and apoptosis of ovarian cancer has not yet been reported. …”
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Klanceng Honey (Tetragonula laeviceps): Its effect on fasting blood glucose, lipid and hematological profiles, and pancreatic histopathology of diabetic rats by Agussalim, Nafiatul Umami, Nurliyani, Wan Iryani Wan Ismail, Dewi Masyithoh, Ustadi, Ali Agus

“…The daily ingestion of KH prevented FBG, TC, TG, and LDL levels from rising, increased the HDL levels, and protected the pancreatic glands against damage. T. laeviceps honey can potentially be used as a functional food for therapy of DM patients.…”
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Neuropathic Pain Management: Prescription Strategies in a Tertiary Care Setting by Chethan Kumar JK, Jason Fernandes Jokem, Chandralekha N, Padmaja Udaykumar

“…Background: Neuropathic pain, resulting from nerve damage, presents a complex challenge in clinical management due to its multifaceted nature and varied patient responses to treatment. …”
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Effect of metformin on the neuronal morphology of frontal cortex and hippocampal regions in lipopolysaccharide induced neuroinflammation in male Wistar rats by Vandana Blossom, Sheetal D. Ullal, Rajalakshmi Rai, Amit Massand, Chettiar Ganesh Kumar, Teresa Joy, Melisha Michael D souza, B.V. Murlimanju

“…Conclusion: The histological analysis and clinical observation by the rotarod test revealed that, metformin attenuated the neuroinflammatory damage, suggesting that it has a neuroprotective role. …”
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Projet MAMIA (Manompana mikajy ny ala) : étude, gestion et conservation des forêts de Manompana. Actions, bilan et perspectives by Ségolène Beaucent, Marc Fayolle

“…While human activities progressively damage and fragment those natural habitats, fauna inventories carried out in the forest of Manompana (lemurs, birds and herpetofauna) keep on showing high species diversity and rich natural area, much of those being still well preserved due to their remoteness. …”
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BACH2 in TRegs Limits the Number of Adipose Tissue Regulatory T Cells and Restrains Type 2 Immunity to Fungal Allergens by Amanda Contreras, Darin L. Wiesner, Brock Kingstad-Bakke, Woojong Lee, John P. Svaren, Bruce S. Klein, M. Suresh

“…FoxP3+ regulatory T cells (Tregs) are essential for self-tolerance and moderating tissue-damaging inflammation. Tregs that develop and mature in the thymus are classified as central Tregs or effector Tregs based on whether Tregs predominately inhabit secondary lymphoid organs (central Tregs) or tissues (effector Tregs). …”
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Xiao-Xu-Ming Decoction Reduced Mitophagy Activation and Improved Mitochondrial Function in Cerebral Ischemia and Reperfusion Injury by Rui Lan, Yong Zhang, Tao Wu, Yun-Zhi Ma, Bao-Qi Wang, Hai-Zhong Zheng, Ya-Na Li, Yan Wang, Chun-Qing Gu, Ji-Tao Wu

“…Autophagy lysosome formation was observed by immunofluorescence labeled with LC3B and Lamp1. The expression of LC3B, Beclin1, and Lamp1 was analyzed by Western blot. …”
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Automated Morphology Detection of Nail-Fold Capillaries Through Enhanced Object Detection Network by Hang Thi Phuong Nguyen, Hieyong Jeong

“…Extensive research supports the notion that nail-fold capillary morphology serves as a critical biomarker for various disease processes, with the degree of capillary structural damage potentially reflecting the involvement of internal organs. …”
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Histopathologic effects of mobile phone radiation exposure on the testes and sperm parameters: a systematic literature review of animal studies by Ebrahim Msaye Assefa, Seid Mohammed Abdu

“…The main targets of mobile phone-induced damage in the testes are Leydig cells, seminiferous tubules, and sperm cells. …”
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风机偏心对空冷梁式桥架振动实验研究 by 郭铁能, 孟令军, 白春生, 华旭

“…The vibration problem of air-cooling fan bridge has been troubling the north thermal power plant.Excessive vibration amplitude causes the damage of fan,motor,reducer and other equipment,and affects the stability and economic benefit of power plant operation.In this paper,the vibration speed of the air-cooling fan exceeded the standard as the research object,and the data acquisition instrument and acceleration sensor were used to test the vibration of the air cooling fan bridge in the power plant of xiaoyi in Shanxi Province.According to the frequency characteristics generated by these incentives,the main influence factors of the vibration of the fan bridge caused by the original fan blades were explored.By analyzing the vibration signal,the main influencing factors of the vibration of fan bridge are explored according to the frequency characteristics.The test results show that the excessive vibration of the bridge is caused by the interference force caused by the fan eccentric mass.During the operation of the fan,the phase of the sensor at the middle of the bridge alternates positively and negatively,and the fan shaft produces a sway,which is inconsistent with the expected horizontal vibration of the bridge.In order to verify the rationality of the above analysis,the finite element analysis of the bridge frame was carried out,and the results are consistent with the above conclusions.Through the forced vibration test and hammer test of the fan bridge,it is found that the maximum frequency value of the vibration of the fan bridge caused by eccentric mass is far away from the natural vibration frequency of the fan bridge,and will not cause the resonance phenomenon of the fan bridge.Therefore,the vibration of the fan bridge caused by eccentric mass is only related to the static stiffness of the fan bridge.The test results will provide a basis for the design of beam bridge and the avoidance of vibration caused by fan eccentricity.…”
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Efficient hydrogen peroxide reduction in glutathione peroxidase cycle using cost-effective FeSe2 nanospheres by Saif Khan, Sundeep S. Bhagwath, Mohammad Rehan Ajmal, Intikhab A. Ansari, Mohtashim Lohani, Sanjaya Pavgada Raghunandana, Mohammad Luqman

“…Their exceptional efficiency makes them a strong candidate for practical applications in mitigating early browning caused by melanogenesis.ConclusionsFeSe2 nanozymes exhibit great promise as a biocatalyst for enhancing the shelf life of fruits and vegetables by reducing damage due to early melanogenesis. This cost-effective and efficient alternative to natural or noble metal-based enzymes offers significant potential for applications in food preservation and other industries.…”
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Single-cell transcriptomic analysis reveals characteristic feature of macrophage reprogramming in liver Mallory-Denk bodies pathogenesis by Zixuan Fang, Bei Zhong, Yi Shi, Wanmei Zhou, Maoping Huang, Samuel W. French, Xiaoping Tang, Hui Liu

“…Furthermore, we revealed the damaged DNA could activate the NOD-like receptor family pyrin domain containing-3 (NLRP3) inflammasome and subsequently form apoptosis-associated speck-like protein containing a caspase recruit domain (ASC) specks of liver macrophages. …”
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Fatigue Experiment and Failure Mechanism Analysis of Aircraft Titanium Alloy Wing–Body Connection Joint by Xianmin Chen, Shanshan Li, Yuanbo Liang, Shuo Wang, Liang Yan, Shichang Du

“…The results show that fretting fatigue is the main driving force for crack initiation, and the crack shows significant fatigue damage characteristics in the stable growth stage and follows Paris’ law. …”
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piR-26441 inhibits mitochondrial oxidative phosphorylation and tumorigenesis in ovarian cancer through m6A modification by interacting with YTHDC1 by Jing Yuan, Bu-Min Xie, Yu-Meng Ji, Hai-Juan Bao, Jie-Lin Wang, Jia-Chen Cheng, Xiang-Chun Huang, Yang Zhao, Shuo Chen

“…The resultant TSFM loss reduced mitochondrial complex I activity and mitochondrial OXPHOS, leading to mitochondrial dysfunction in OC cells, increased reactive oxygen species levels, and thus, DNA damage and apoptosis in OC cells, thereby inhibiting OC progression. …”
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Complications and Mortality Characterization in Acute Ischemic Cerebrovascular Disease by Ricardo Leyva Tornés, Lázaro Ibrahim Romero García, Esther Mayor Guerra, Yordanis Páez Candelaria, Karima Gondres Legró, Pedro Alexei Bacardí Zapata

“…<br /><strong>Objective:</strong> to describe the most frequent complications incidence in the patients suffering from cerebrovascular disease population, as well as the burden of mortality associated with this neurological damage. <br /><strong>Method:</strong> a descriptive study was carried out in patients with ischemic cerebrovascular disease who leaved from the Neurology Service of the Saturnino Lora Torres Provincial Clinical Surgical Teaching Hospital in the 2017-2019 triennium. …”
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The First Report of Tomato Yellow Leaf Curl Virus (TYLCV) Occurrence in Tomato Greenhouses of Lorestan Province by Farzaneh Rostami, Samira Pakbaz, Mostafa Darvishnia

“…Tomato yellow leaf curl virus (TYLCV) is one of the most important tomatoes (Solanum lycopersicum L.) viral diseases in tropical, subtropical, and temperate regions of the world. The amount of damage caused by this virus is severe and may reach 100%. …”
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Relations on Ensuring the Rights and Freedoms of a Man and Citizen as a Component of the Subject Matter of Administrative Law by A. T. Komziuk, Ye. A. Lypii

“…However, it is no less important to maintain proper public order and security, to counteract to various illegal manifestations that infringe on these rights and freedoms, causing some damage, sometimes quite significant. The conclusion is made about the expediency of taking into account the relations concerning the provision of human rights and freedoms and its elements, in particular protection and defense in the construction of the system of administrative law.…”
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Functional Connectivity and MRI Radiomics Biomarkers of Cognitive and Brain Reserve in Post-Stroke Cognitive Impairment Prediction—A Study Protocol by Hanna Maria Dragoș, Adina Stan, Livia Livinț Popa, Roxana Pintican, Diana Feier, Nicu Cătălin Drăghici, Dragoș-Cătălin Jianu, Diana Chira, Ștefan Strilciuc, Dafin F. Mureșanu

“…Brain reserve refers to the brain’s structural capacity to compensate for damage, with markers like hippocampal atrophy and white matter lesions indicating reduced reserve. …”
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Assessment of Parents’ Awareness Towards Space Maintainers: A Cross‑Sectional Study by Esra Ceren Tuğutlu, Neslihan Yılmaz

“…Descriptive statistical analysis was employed to interpret the findings.Results: Despite the fact that 45% children lost primary teeth due to decay, trauma or other reasons, 40.9% of parents declared that they had no idea that early loss of primary teeth could damage permanent teeth. Additionally, only 35.8% of parents stated that they had knowledge of what a space maintainer is; it was found that those parents who were familiar with space maintainers also had a high level of knowledge about its use.Conclusions: It is concluded that there is a need to enhance parental awareness concerning the utilization of space maintainers as a preventive measure following the premature loss of primary teeth.…”
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Cystatin C Levels in Middle-Aged Patients with Obstructive Sleep Apnea Syndrome by Kostas Archontogeorgis, Evangelia Nena, Christina Tsigalou, Athanasios Voulgaris, Maria Xanthoudaki, Marios Froudarakis, Paschalis Steiropoulos

“…Cystatin C (Cyst C) is a novel biomarker of both latent renal damage and cardiovascular disease. Aim of the study was to measure serum levels of Cyst C, as well as IL-8 and CRP, in otherwise healthy OSAS patients. …”
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