DICER1: The Argonaute Endonuclease Family Member and Its Role in Pediatric and Youth Pathology by Consolato M. Sergi, Fabrizio Minervini

“…This enzyme functions in numerous pathways, including RNA interference paths, DNA damage renovation, and response to viruses. At the protein level, DICER is also involved in several human diseases, of which the pleuro-pulmonary blastoma is probably the most egregious entity. …”
Get full text

Urban Vulnerability Analysis Against earthquake hazard With the ELECTRE FUZZY method (Case Study: Karaj Metropolis) by Fatemeh Khodadadi, Mojgan Entezari, Farzaneh Sasanpour

“…According to the principles of urban planning, the regulations of 2800 can cover earthquake damage in these areas.…”
Get full text

Daily Assistance for Amyotrophic Lateral Sclerosis Patients Based on a Wearable Multimodal Brain-Computer Interface Mouse by Ya Jiang, Kendi Li, Yuankai Liang, Di Chen, Mingkui Tan, Yuanqing Li

“…Amyotrophic lateral sclerosis (ALS) is a chronic, progressive neurodegenerative disease that mainly causes damage to upper and lower motor neurons. This leads to a progressive deterioration in the voluntary mobility of the upper and lower extremities in ALS patients, which underscores the pressing need for an assistance system to facilitate communication and body movement without relying on neuromuscular function. …”
Get full text

Retrofitting of a Multi-Span Simply Supported Bridge into a Semi-Integral Bridge by Zhen Xu, Xiaoye Luo, Khaled Sennah, Baochun Chen, Yizhou Zhuang

“…They often suffer from problems of cracks in the link slabs over piers, and the deterioration and damage of deck expansion joints at abutments. To address these problems, one approach is to retrofit them by converting the simply supported box beams into continuous structures over the piers and jointless bridges over the abutments. …”
Get full text

Simultaneous evaluation of restless leg syndrome, neuropathic pain, disease activity, and quality of life in patients with Takayasu arteritis: a cross-sectional study by Emel Oğuz Kökoğlu, Melih Kızıltepe, Hüseyin Kaplan, Senem Şaş, Tuğba Kahraman Denizhan, Abdurrahman Soner Şenel

“…The SF-36 subscale scores for physical functioning (p = 0.01) and general health (p = 0.002) were significantly lower in the TAK group than in the control group. Vasculitis Damage Index (VDI) scores were considerably higher in patients with NeP (p = 0.004). …”
Get full text

Development of a Deep Learning‐Assisted Mobile Application for the Identification of Nematodes Through Microscopic Images by Naseeb Singh, Ashish Kumar Singh, L. K. Dhruw, Simardeep Kaur, S. Hazarika, K. K. Mishra, V. K. Mishra, Laxmi Kant

“…ABSTRACT Nematodes are microscopic metazoans, some species of which can be used as biological insecticides, while some other species annually damage 10.0%–20.0% of crops globally. Accurate identification of nematodes is crucial for their effective utilisation or control. …”
Get full text

Mapping subcortical brain lesions, behavioral and acoustic analysis for early assessment of subacute stroke patients with dysarthria by Juan Liu, Juan Liu, Rukiye Ruzi, Chuyao Jian, Qiuyu Wang, Shuzhi Zhao, Manwa L. Ng, Shaofeng Zhao, Lan Wang, Nan Yan

“…IntroductionDysarthria is a motor speech disorder frequently associated with subcortical damage. However, the precise roles of the subcortical nuclei, particularly the basal ganglia and thalamus, in the speech production process remain poorly understood.MethodsThe present study aimed to better understand their roles by mapping neuroimaging, behavioral, and speech data obtained from subacute stroke patients with subcortical lesions. …”
Get full text

SARS-CoV-2 ORF3a accessory protein is a water-permeable channel that induces lysosome swelling by Antonio Michelucci, Luigi Sforna, Riccardo Focaia, Maria Vittoria Leonardi, Angela Di Battista, Giorgia Rastelli, Simone Vespa, Simona Boncompagni, Manlio Di Cristina, Luigi Catacuzzeno

“…Finally, ORF3a expression in HEK293 cells leads to lysosomal volume increase, mitochondrial damage, and accumulation of intracellular membranes, all alterations reverted by the N82W mutation. …”
Get full text

Des céréales locales pour la transition climatique et alimentaire. Pratiques paysannes et pratiques féminines sur les sorghos et les mils du Sahel sénégalais au Deccan indien. by Danièle Clavel, Hélène Guétat-Bernard, Éric Verger

“…This analysis revealed strong links between the agro-environmental consequences of the agricultural changes analyzed, their food translations and the cultural losses that result: the intensification of rice in the Senegal River Valley and of VR in India not only cause a decline in the agricultural biodiversity of local cereals, but also damage the adaptive capacities and nutritional quality of meals and the quality of life. …”
Get full text

Case report: Clinical characteristics and Genetical analysis of HSD11B2 in three Chinese children with apparent mineralocorticoid excess: a case series by Yuan Ding, Yuan Ding, Ming Cheng, Ming Cheng, Bingyan Cao, Bingyan Cao, Min Liu, Min Liu, Xuyun Hu, Xuyun Hu, Di Wu, Di Wu, Di Wu

“…Such measures are essential for the prevention or mitigation of target organ damage, as well as for the reduction of associated morbidity and mortality…”
Get full text

Analysis of seepage through an earth dam with a diaphragm on an impermeable foundation using PLAXIS 2D by G. V. Orekhov, Tran Manh Cuong

Subjects: Get full text

Mercury Vapour Long-Lasting Exposure: Lymphocyte Muscarinic Receptors as Neurochemical Markers of Accidental Intoxication by E. Roda, A. Giampreti, S. Vecchio, P. Apostoli, T. Coccini

“…Chronic poisoning may result in home setting after mercury (Hg) vapours inhalation from damaged devices. We report a chronic, nonoccupational Hg poisoning due to 10-year indoor exposure to mercury spillage. …”
Get full text

Single-cell transcriptomics identify a novel macrophage population associated with bone invasion in pituitary neuroendocrine tumors by Xinzhi Wu, Xueshuai Han, Haibo Zhu, Mingxuan Li, Lei Gong, Sicheng Jing, Weiyan Xie, Zhaoqi Liu, Chuzhong Li, Yazhuo Zhang

“…This infiltration poses a significant surgical risk due to potential damage to vital nerves and arteries. However, the mechanisms underlying bone invasion caused by PitNETs remain elusive, and effective interventions for PitNET-induced bone invasion are lacking in clinical practice. …”
Get full text

Crisis Spreading Model of the Shareholding Networks of Listed Companies and Their Main Holders and Their Controllability by Yuanyuan Ma, Lingxuan Li

“…However, the crisis will spread at a high speed and cause catastrophic damage if there are some failures or attacks on hub vertices in the networks. …”
Get full text

Optic Disc Vascularization in Glaucoma: Value of Spectral-Domain Optical Coherence Tomography Angiography by Pierre-Maxime Lévêque, Pierre Zéboulon, Emmanuelle Brasnu, Christophe Baudouin, Antoine Labbé

“…In glaucoma patients OCT-A might detect reduced ONH blood vessel density that is associated with structural and functional glaucomatous damage. OCT-A might become a useful tool for the evaluation of ONH microcirculation changes in glaucoma.…”
Get full text

Proton Pump Inhibitor-Induced Galactorrhea in a Kidney Transplant Recipient: A Friend or Foe? by Marios Prikis, Julie MacDougall, Nina Narasimhadevara

“…In the setting of renal dysfunction, these metabolites will not be excreted from the body and will accumulate further causing kidney damage and inhibiting CYP enzymes to a greater extent. …”
Get full text

Trichostatin A promotes de novo shoot regeneration from Arabidopsis root explants via a cytokinin related pathway by Su Hyun Park, Yu Jeong Jeong, Soyoung Kim, Jiyoung Lee, Cha Young Kim, Jae Cheol Jeong

“…Abstract De novo shoot regeneration, characterized by the emergence of adventitious shoots from excised or damaged tissues or organs in vitro, is regulated by the complex interplay between genetic and epigenetic regulatory mechanisms. …”
Get full text

The Expression of miR-34a in Gingival Crevicular Fluid of Chronic Periodontitis and Its Connection with the TLR/NF-κB Signaling Pathway by Jiaxin Pan, Jue Liu, Lu Zhao

“…Its expression is associated with the degree of periodontal inflammation, periodontal tissue damage, and the activation of the TLR/NF-κB signaling pathway and could be used as a potential index for auxiliary diagnosis and severity of the disease.…”
Get full text

GASTROINTESTINAL PARASITES AND ASSOCIATED GUT PATHOLOGY IN CHICKENS SOLD AT LIVE-BIRD MARKETS IN LAGOS STATE, SOUTHWESTERN NIGERIA by Oluwayomi Oluwatoyin Adeyemi, Emmanuel Taiwo Idowu, Bamidele Akinsanya, Isa Danladi Jatau, Temitope Morenikeji Oladipo

“…This study showed that GI parasites are prevalent in chickens and are associated with intestinal damage that can undermine poultry growth and productivity in the study area. …”
Get full text

MMP-9 Contributes to Dendritic Spine Remodeling Following Traumatic Brain Injury by Barbara Pijet, Marzena Stefaniuk, Leszek Kaczmarek

“…Traumatic brain injury (TBI) occurs when a blow to the head causes brain damage. Apart from physical trauma, it causes a wide range of cognitive, behavioral, and emotional deficits including impairments in learning and memory. …”
Get full text