Inhibition of Viability, Proliferation, Cytokines Secretion, Surface Antigen Expression, and Adipogenic and Osteogenic Differentiation of Adipose-Derived Stem Cells by Seven-Day Ex... by Jian Wang, Bo Xiang, Jixian Deng, Darren H. Freed, Rakesh C. Arora, Ganghong Tian

“…The SMF slightly reduced cell viability and proliferation and inhibited the expression of CD49d, CD54, and CD73 but did not damage DNA integrity. The SMF slightly downregulated the expression of cytokines including Vascular Endothelial Growth Factor (VEGF), Insulin-like Growth Factor-1 (IGF-1), Transforming Growth Factor Beta 1 (TGF-β1), genetic markers comprising Stem Cell Antigen-1 (Sca1), Octamer-4 (Oct-4), ATP-binding Cassette Subfamily B Member 1 (ABCB1), adipogenic marker genes containing Lipoprotein Lipase (LPL), Peroxisome Proliferator-Activated Receptor Gamma (PPAR-γ), and osteogenic marker genes including Secreted Phosphor-protein 1 (SPP1) and Osterix (OSX). …”
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Seismic Evaluation and Retrofit of Reinforced Concrete Buildings with Masonry Infills Based on Material Strain Limit Approach by Mangeshkumar R. Shendkar, Denise-Penelope N. Kontoni, Sasankasekhar Mandal, Pabitra Ranjan Maiti, Omid Tavasoli

“…This method is based on the threshold strain limit of concrete and steel to identify the actual damage scenarios of the structural members of RC structures. …”
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Metabolomics and Lipidomics Reveal the Metabolic Disorders Induced by Single and Combined Exposure of Fusarium Mycotoxins in IEC-6 Cells by Xinlu Wang, Yanyang Xu, Haiqi Yu, Yushun Lu, Yongzhong Qian, Meng Wang

“…Some of the differential compounds were endocellular antioxidants and were significantly downregulated in mycotoxin exposure groups, indicating metabolic disorders as well as antioxidant capacity damage in cells. Pathway enrichment analysis annotated ethanol metabolism production of ROS by CYP2E1 was mainly involved in the disturbance of DON, FB₁, and ZEN. …”
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Intestinal oxygen utilisation and cellular adaptation during intestinal ischaemia–reperfusion injury by Paraschos Archontakis‐Barakakis, Theodoros Mavridis, David‐Dimitris Chlorogiannis, Georgios Barakakis, Eleni Laou, Daniel I. Sessler, George Gkiokas, Athanasios Chalkias

“…Restoration of perfusion and oxygenation provokes additional injury, resulting in mucosal damage and disruption of intestinal barrier function. …”
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Verification of the Efficacy of Passive Autocatalytic Recombiners in a Typical Pressurized Water Reactor under a Station Blackout Condition by Daegwang Hong, Donghyun Cho, Jinwoo Kim, Aya Diab, Cigdem Cildag

“…An extended station blackout (SBO) was chosen as an initiating event given its high contribution to the core damage frequency. RCS depressurization and external injection are mitigation techniques implemented consecutively to extend the coping capability of the plant for the extended SBO scenario. …”
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Techniques of Ozone Monitoring in a Mountain Forest Region: Passive and Continuous Sampling, Vertical and Canopy Profiles by Giacomo Gerosa, Cristina Mazzali, Antonio Ballarin-Denti

“…Ozone is the most harmful air pollutant for plant ecosystems in the Mediterranean and Alpine areas due to its biological and economic damage to crops and forests. In order to evaluate the relation between ozone exposure and vegetation injury under on-field conditions, suitable ozone monitoring techniques were investi-gated. …”
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In vivo efficacy and safety of systemically administered serinol nucleic acid-modified antisense oligonucleotides in mouse kidney by Toshiki Tsuboi, Keita Hattori, Takuji Ishimoto, Kentaro Imai, Tomohito Doke, Junichiro Hagita, Jumpei Ariyoshi, Kazuhiro Furuhashi, Noritoshi Kato, Yasuhiko Ito, Yukiko Kamiya, Hiroyuki Asanuma, Shoichi Maruyama

“…Moreover, SGLT2-SNA-ASO did not cause severe liver damage, unlike SGLT2-MOE-ASO. The administration of Cy5-labeled-ASOs demonstrated an early increase in renal uptake, particularly in the renal proximal tubules, when modified with SNA. …”
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He effectivness and expedicency of the International Court of Justice interim measures by Bjelica-Vlajić Iris N.

“…Along with both requests for the initiation of proceedings, provisional measures were requested, in accordance with the Statute and Rules of Procedure of the Court, in the first case to end the armed actions, and in the second, to protect the rights of the civilian population from further, severe and irreparable damage, and ensure compliance with obligations from the Convention on the Prevention and Punishment of the Crime of Genocide (Genocide Convention). …”
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Liver laceration as a post-cardiopulmonary resuscitation complication in a person with breast implants: a case report by Min-Jeong Cho

“…Electroencephalography showed generalized attenuation, indicating severe global brain damage. Liver injury is a relatively rare post-CPR complication, with an incidence of 0.6% according to a retrospective analysis of a cardiac arrest registry. …”
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Deterioration of the Internal Structure of Loess under Dry-Wet Cycles by Wanjun Ye, Yang Bai, Chenyang Cui, Xu Duan

“…To understand the structural damage evolution process of loess under the action of dry-wet cycles, a triaxial test of a dry-wet cycle was performed by considering three influencing factors: initial moisture content, amplitude of the dry-wet cycle, and number of dry-wet cycles. …”
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Meteorological Analysis of Floods in Ghana by S. O. Ansah, M. A. Ahiataku, C. K. Yorke, F. Otu-Larbi, Bashiru Yahaya, P. N. L. Lamptey, M. Tanu

“…We applied the Weather Research and Forecasting (WRF) model to investigate and examine the meteorological dynamics, which resulted in the extreme rainfall and floods that caused 14 deaths, 34076 people being displaced with damaged properties, and economic loss estimated at $168,289 for the two cities according to the National Disaster Management Organization (NADMO). …”
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The Effect of St. John’s Wort Oil on Urethral Stricture: An Experimental Study in Rat Model by Kazım Yelsel, Ergün Alma, Ömer Yüceer, Zeynel Abidin Taş, Berna Totan Ateş, Murat Kobaner, Halil Esimek, Adem Altunkol, Umut Ünal, Ali Ayyıldız

“…Methods: A total of 24 male rats were divided into 5 groups. No urethral damage was induced in the sham group. The urethras of all rats in the other groups was traumatized at 6 o’clock with a specially designed urethrotome blade. …”
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Intensification of Natural Disasters in the State of Pará and the Triggering Mechanisms Across the Eastern Amazon by Everaldo B. de Souza, Douglas B. S. Ferreira, Luciano J. S. Anjos, Alan C. Cunha, João Athaydes Silva, Eliane C. Coutinho, Adriano M. L. Sousa, Paulo J. O. P. Souza, Waleria P. Monteiro Correa, Thaiane S. Silva Dias, Alexandre M. C. do Carmo, Carlos B. B. Gutierrez, Giordani R. C. Sodré, Aline M. M. Lima, Edson J. P. Rocha, Bergson C. Moraes, Luciano P. Pezzi, Tercio Ambrizzi

“…The catastrophic impacts on people and the economy were documented, showing a significant rise in the number of homeless individuals and those directly affected, alongside considerable material damage and economic losses for both the public and private sectors. …”
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Experimental Study and Numerical Analysis on Impact Resistance of Civil Air Defense Engineering Shear Wall by Chenglong Shi, Jigang Zhang, Junbo Zhang, Feng Shao, Yicong Zhang, Menglin Zhang

“…Through multiple impact tests on the civil air defense engineering shear wall, the civil air defense engineering shear wall had accumulated damage. The longitudinally loaded steel on the back reached the ultimate strength, and there are large cracks at the bottom and even collapses. …”
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Poor quality of life in indian ankylosing spondylitis patients by Latika Gupta, Sakir Ahmed, Gautam Dhar Choudhury, Durga Prasanna Misra, Vikas Agarwal

“…Apart from demographic variable such as age, gender, clinical manifestations, and treatment received, disease activity parameters such as duration of early morning stiffness, BASDAI, swollen and tender joint count, Erythrocyte Sedimentation Rate (ESR) and C Reactive Protein (CRP) were also recorded. Presence of damage was assessed using spinal radiographs. All values are in median (IQR). …”
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The reuse of peanut organic wastes as a growth medium for ornamental plants by A. Mohammadi Torkashvand, M. Alidoust, A. Mahboub Khomami

“…Most plants with ornamental leaves are cultivated in soilless media, in which peat is the basic medium; but the use of peat is questionable due to ecological damage to the environment and economic disadvantages to ornamental plant producers. …”
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Smart Deployable Scissor Lift Brace to Mitigate Earthquake Risks of Soft-Story Buildings by Vijayalaxmi Rangrej, Ricky W. K. Chan

“…The soft-story effect, characterized by a sudden reduction in lateral stiffness in one or more levels of a building, often leads to catastrophic collapses during large earthquakes, resulting in significant structural damage and loss of life. The proposed system is triggered by signals from the Earthquake Early Warning (EEW) system, advanced technologies capable of detecting and broadcasting earthquake alerts within seconds which are currently implemented in countries and regions such as Japan, parts of the USA, and parts of Europe. …”
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Assessing urban quality of life using remote sensing and GIS (Case study: Urmia Urban Region) by ali khedmatzadeh, Bakhtaran Feizizadeh

“…The existence of spatial and spatial inequalities in the city has caused many problems, including the weakness of resources, inappropriate housing, the problems and damage caused by social inequalities, and undermined the quality of life. …”
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Pleiotropic effects of mutant huntingtin on retinopathy in two mouse models of Huntington's disease by Hui Xu, Anakha Ajayan, Ralf Langen, Jeannie Chen

“…This mutant huntingtin protein (mHTT) with extended polyQ forms aggregates in cortical and striatal neurons, causing cell damage and death. The retina is part of the central nervous system (CNS), and visual deficits and structural abnormalities in the retina of HD patients have been observed. …”
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Experimental Study on Freeze-Thaw Effects on Creep Characteristics of Rubber Concrete by Qi Li, Fei Xu, Hemin Zheng, Junhao Shi, Jianyu Zhang

“…Finally, a Weibull distribution-based empirical creep damage model was established to predict the failure of CRC, which can enhance its application to related engineering.…”
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