Findings from the Tushirikiane-4-MH (supporting each other for mental health) mobile health–supported virtual reality randomized controlled trial among urban refugee youth in Kampa... by Carmen H. Logie, Moses Okumu, Zerihun Admassu, Frannie MacKenzie, Lesley Gittings, Jean-Luc Kortenaar, Naimul Khan, Robert Hakiza, Daniel Kibuuka Musoke, Aidah Nakitende, Brenda Katisi, Peter Kyambadde, Richard Lester, Lawrence Mbuagbaw

Get full text

An Investigation of Manifold-Based Direct Control for a Brain-to-Body Neural Bypass by E. Losanno, M. Badi, E. Roussinova, A. Bogaard, M. Delacombaz, S. Shokur, S. Micera

“…We then tested the animal's ability to directly control a computer cursor using cortical activation along the manifold axes. …”
Get full text

Rehabilitation using virtual gaming for Hospital and hOMe-Based training for the Upper limb in acute and subacute Stroke (RHOMBUS II): results of a feasibility randomised controlle... by Cherry Kilbride, Tom Butcher, Meriel Norris, Nana Anokye, Alyson Warland, Karen Baker, Dimitrios A Athanasiou, Guillem Singla-Buxarrais, Jennifer Ryan, Francesca Gowing, Elmar Kal, Carole Pound, Victoria Stewart, Basaam Aweid, Arul Samiyappan

“…Impairment, activity and participation outcomes were also collected at baseline and 7 weeks to assess their suitability for use in a definitive trial.Randomisation Computer-generated, allocation sequence concealed by opaque, sealed envelopes.Blinding Participants and assessors were not blinded; statistician blinded for data processing and analysis.Results 192 stroke survivors were screened for eligibility, and 24 were recruited and randomised. …”
Get full text

Association between prenatal maternal sleep quality, neonatal uncinate fasciculus white matter, and infant negative emotionalityResearch in context by Melissa Nevarez-Brewster, Catherine H. Demers, LillyBelle K. Deer, Özlü Aran, Robert J. Gallop, Mercedes Hoeflich Haase, Khalid Al-Ali, Maria M. Bagonis, John H. Gilmore, M. Camille Hoffman, Martin A. Styner, Benjamin L. Hankin, Elysia Poggi Davis

Get full text

Effects of an online-based motivational intervention to reduce problematic internet use and promote treatment motivation in internet gaming disorder and internet use disorder (OMPR... by Stephan Herpertz, Peter Henningsen, Jan Dieris-Hirche, Laura Bottel, Magdalena Pape, Bert Theodor te Wildt, Klaus Wölfling, Nina Timmesfeld, Anja Neumann, Silke Neusser, Rainer Beckers

“…Two follow-up assessments will be conducted after 6 weeks (T3) and 6 months (T4) after the intervention. …”
Get full text

Classifying active and inactive states of growing rabbits from accelerometer data using machine learning algorithms by Mónica Mora, Lucile Riaboff, Ingrid David, Juan Pablo Sánchez, Miriam Piles

Get full text

Barriers and Facilitators in Implementing a Telemonitoring Application for Patients With Chronic Kidney Disease and Health Professionals: Ancillary Implementation Study of the NeLL... by Marion Delvallée, Abdallah Guerraoui, Lucas Tchetgnia, Jean-Pierre Grangier, Nassira Amamra, Anne-Laure Camarroque, Julie Haesebaert, Agnès Caillette-Beaudoin

“…Among the 128 patients, 46 (35.9%) reported using the application at least once a week. The main barriers for patients were issues related to computer use, as well as the lack of feedback and communication with health care professionals. …”
Get full text

Transcriptional profiles of Microcystis reveal gene expression shifts that promote bloom persistence in in situ mesocosms by Lauren E. Krausfeldt, Paisley S. Samuel, Robert P. Smith, Hidetoshi Urakawa, Barry H. Rosen, Rita R. Colwell, Jose V. Lopez

Get full text

Psychometric characteristics and feasibility of microinteraction-based Ecological Momentary Assessment in audiology research by Yu-Hsiang Wu, Elizabeth Stangl, Samuel Smith, Jacob Oleson, Christi Miller, Octav Chipara

Get full text

Exploratory imaging outcomes of a phase 1b/2a clinical trial of allopregnanolone as a regenerative therapeutic for Alzheimer's disease: Structural effects and functional connectivi... by Adam C. Raikes, Gerson D. Hernandez, Dawn C. Matthews, Ana S. Lukic, Meng Law, Yonggang Shi, Lon S. Schneider, Roberta D. Brinton

“…Methods Twenty‐four individuals participated in the trial (n = 6 placebo; n = 18 ALLO) and underwent brain magnetic resonance imaging (MRI) before and after 12 weeks of treatment. Hippocampal atrophy rate was determined from volumetric MRI, computed as rate of change, and qualitatively assessed between ALLO and placebo sex, apolipoprotein E (APOE) ε4 allele, and ALLO dose subgroups. …”
Get full text

Using Video Cameras to Assess Physical Activity and Other Well-Being Behaviors in Urban Environments: Feasibility, Reliability, and Participant Reactivity Studies by Jack S Benton, James Evans, Jamie Anderson, David P French

“…It also provides a rigorous foundation for developing more scalable automated computer vision algorithms for assessing human behaviors.…”
Get full text

Glycemic control in women with GDM: insights from a randomized controlled pilot trial on plant-based Nordic healthy diet versus moderately carbohydrate restricted diet by Lisa Torsdatter Markussen, Jemina Kivelä, Jaana Lindström, Miina Ollikainen, Mikko Kytö, Seppo Heinonen, Saila Koivusalo, Jelena Meinilä

Get full text

Does digital, multimedia information increase recruitment and retention in a children’s wrist fracture treatment trial, and what do people think of it? A randomised controlled Stud... by Jacqueline M Martin-Kerry, Peter Knapp, Steven Higgins, Rebecca Sheridan, Juul Achten, Duncan Appelbe, Louise Spoors, Thirimon Moe-Byrne, Daniel Perry, Jenny Roche

“…Almost all FORCE recruits were retained at the 6 weeks’ timepoint and there was no difference in retention rate between the information groups: MMI (473; 99.6%); PIS (481; 99.4%).Conclusions MMI did not increase recruitment or retention in the FORCE trial, but participants rated multimedia as easier to understand and were more likely to evaluate it positively.Trial registration number ISRCTN73136092 and ISRCTN13955395.…”
Get full text

Effects of chronic psychological stress on testicular cell senescence in rats and role of glucocorticoid receptor in the process by YANG Binwei, YANG Binwei, SUN Lei, LING Xi

“…Methods Thirty-two male SD rats (4~6 weeks old, weighing 120~140 g) were randomly assigned into dimethyl sulfoxide (DMSO) group, mifepristone (RU486) group, chronic unpredictable mild stress (CUMS) group, and CUMS+RU486 group.DMSO of 0.5 ml/(kg·d) was injected subcutaneously into the rats of DMSO group.After the rats of the CUMS group were exposed to CUMS, mifepristone of 1 mg/(kg·d) was given to the rats of the RU486 group and CUMS+RU486 group.All the above 4 groups were inflicted for 42 consecutive days.After modeling, the psychological stress status of rats was evaluated with animal behavioral experiments.Computer-aided sperm analysis (CASA) system was used to detect sperm density.ELISA was employed to measure the serum levels of corticosterone (CORT), sex hormones and inflammation factors.The contents of malondialdehyde (MDA), H2O2, NAD+/NADH and ATP in the testicular tissues were tested with corresponding reagent kits.Western blotting was utilized to detect protein levels of β-gal, p16, and GR in testicular tissue, and transmission electron microscopy was used to observe mitochondrial structure of spermatogenic cells. …”
Get full text

Improving mental health and physiological stress responses in mothers following traumatic childbirth and in their infants: study protocol for the Swiss TrAumatic biRth Trial (START... by Myriam Bickle-Graz, Jean-François Tolsa, Antje Horsch, Mathilde Morisod Harari, Emily A Holmes, Vania Sandoz, Camille Deforges, Suzannah Stuijfzand, Manuella Epiney, Yvan Vial, Nicole Sekarski, Nadine Messerli-Bürgy, Ulrike Ehlert, Kate Porcheret, Daniel S Schechter, Susan Ayers, Valérie Avignon, Cristina Borradori Tolsa, Julie Bourdin, Dominique Delecraz, David Desseauve, Isabelle Eragne, Emily A. Holmes, Justine Imbert, Micah M. Murray, Jardena J. Puder, Véronique Othenin-Girard, Daniel S. Schechter

“…There is accumulating evidence that a brief behavioural intervention including a visuospatial task may result in a reduction in intrusive memories of the trauma.Methods and analysis This study protocol describes a double-blind multicentre randomised controlled phase III trial testing an early brief maternal intervention including the computer game ‘Tetris’ on intrusive memories of the ECS trauma (≤1 week) and PTSD symptoms (6 weeks, primary outcome) of 144 women following an ECS. …”
Get full text

Distinct Circle of Willis anatomical configurations in healthy preterm born adults: a 3D time-of-flight magnetic resonance angiography study by Julien Greggio, Christina Malamateniou, Kelly Pegoretti Baruteau, Constantino Carlos Reyes-Aldasoro, Odaro J. Huckstep, Jane M. Francis, Wilby Williamson, Paul Leeson, Adam J. Lewandowski, Winok Lapidaire

Get full text

Towards a Crowdsourced Digital Coffee Atlas for Sustainable Coffee Farming by Emma Krischkowsky, Onur Bal, Colin Beyer, David Miller, Manuel Walter, Kirstin Kohler

“…The present work summarizes the results of a 15-week student project addressing the field of sustainable coffee farming. …”
Get full text

Changes in laboratory value improvement and mortality rates over the course of the pandemic: an international retrospective cohort study of hospitalised patients infected with SARS... by Ramakanth Kavuluru, Xuan Wang, Paul Avillach, Florence Bourgeois, Kee Yuan Ngiam, Gabriel A Brat, Isaac Kohane, Tianxi Cai, Yuk-Lam Ho, Yuan Luo, Harrison G Zhang, Kelly Cho, Vincent Benoit, Antoine Neuraz, Chuan Hong, Sehi L'Yi, Griffin Weber, Bryce W Q Tan, Alba Gutiérrez-Sacristán, Clara-Lea Bonzel, Nathan P Palmer, Alberto Malovini, Valentina Tibollo, Meghan R Hutch, Molei Liu, Riccardo Bellazzi, Luca Chiovato, Fernando J Sanz Vidorreta, Trang T Le, William Yuan, Bertrand Moal, Michele Morris, David A Hanauer, Sarah Maidlow, Kavishwar Wagholikar, Shawn Murphy, Hossein Estiri, Adeline Makoudjou, Patric Tippmann, Jeffery Klann, Robert W Follett, Nils Gehlenborg, Gilbert S Omenn, Zongqi Xia, Arianna Dagliati, Shyam Visweswaran, Lav P Patel, Danielle L Mowery, Emily R Schriver, Malarkodi Jebathilagam Samayamuthu, Sara Lozano-Zahonero, Daniela Zöller, Amelia L M Tan, Byorn W L Tan, John H Holmes, Petra Schubert, Brett K. Beaulieu-Jones, Miguel Pedrera-Jiménez, Noelia García-Barrio, Pablo Serrano-Balazote, Andrew South

Get full text

Interleukin-10 exhibit dose-dependent effects on macrophage phenotypes and cardiac remodeling after myocardial infarction by Jing J. Zhang, Rodrigue Rizk, Xiaoping Li, Brandon G. Lee, Mason L. Matthies, Kennedy A. Bietz, Kang Kim, Kang Kim, Kang Kim, Johnny Huard, Yadong Wang, William C. W. Chen

Get full text

Effects of Different Types of Cognitive Training on Cognitive Function, Brain Structure, and Driving Safety in Senior Daily Drivers: A Pilot Study by Takayuki Nozawa, Yasuyuki Taki, Akitake Kanno, Yoritaka Akimoto, Mizuki Ihara, Ryoichi Yokoyama, Yuka Kotozaki, Rui Nouchi, Atsushi Sekiguchi, Hikaru Takeuchi, Carlos Makoto Miyauchi, Takeshi Ogawa, Takakuni Goto, Takashi Sunda, Toshiyuki Shimizu, Eiji Tozuka, Satoru Hirose, Tatsuyoshi Nanbu, Ryuta Kawashima

“…Before and after the 8-week training period, they underwent neuropsychological tests, structural brain magnetic resonance imaging, and driving safety tests. …”
Get full text