The Mid-Twentieth Century Baby Boom and the Role of Social Influence. An Agent-Based Modelling Approach by Eli Nomes, André Grow, Jan Van Bavel

“…Overall, this led to a reduction of childlessness and thus an increase of fertility, as more people aspired to have at least two children. Yet, in those regions where larger family sizes were still common, the two-child norm contributed to a fertility decline. …”
Get full text

Neutralizing antibody landscape of the non-polio Enteroviruses and future strategy by Hongye Wang, Wenbing Zhu, Ya Li, Ming Sun

“…In recent years, several NPEVs have become serious public health threats, include EV-A71, which has caused epidemics of hand-foot-and-mouth disease (HMFD) in Southeast Asia, and EV-D68, which caused outbreaks of severe respiratory disease in children worldwide. Infections with these viruses are associated with neurological diseases like aseptic meningitis and AFP. …”
Get full text

Structurally convergent antibodies derived from different vaccine strategies target the influenza virus HA anchor epitope with a subset of VH3 and VK3 genes by Ting-Hui Lin, Chang-Chun David Lee, Monica L. Fernández-Quintero, James A. Ferguson, Julianna Han, Xueyong Zhu, Wenli Yu, Jenna J. Guthmiller, Florian Krammer, Patrick C. Wilson, Andrew B. Ward, Ian A. Wilson

Get full text

Unveiling new perspectives about the onset of neurological and cognitive deficits in cerebral malaria: exploring cellular and neurochemical mechanisms by Renato M. S. de Lima, Luana K. R. Leão, Luana C. Martins, Adelaide da C. Fonseca Passos, Evander de J. Oliveira Batista, Anderson M. Herculano, Karen R. H. M. Oliveira

“…These neurotransmitters pathways may play a crucial role in the pathogenesis of cerebral malaria, potentially interacting with other molecular players. By enhancing our understanding in the pathophysiology of cerebral malaria, this article seeks to explore new hypotheses regarding the involvement of neurotransmitters and their interactions with other molecular targets, thereby contributing to the overall pathology of cerebral malaria.…”
Get full text

Neural markers of error processing relate to task performance, but not to substance-related risks and problems and externalizing problems in adolescence and emerging adulthood by Olga D. Boer, Thea Wiker, Shervin H. Bukhari, Rikka Kjelkenes, Clara M.F. Timpe, Irene Voldsbekk, Knut Skaug, Rune Boen, Valerie Karl, Torgeir Moberget, Lars T. Westlye, Ingmar H.A. Franken, Hanan El Marroun, Rene J. Huster, Christian K. Tamnes

Get full text

Therapeutic role of miR-26a on cardiorenal injury in a mice model of angiotensin-II induced chronic kidney disease through inhibition of LIMS1/ILK pathway by Weijie Ni, Yajie Zhao, Jinxin Shen, Qing Yin, Yao Wang, Zuolin Li, Taotao Tang, Yi Wen, Yilin Zhang, Wei Jiang, Liangyunzi Jiang, Jinxuan Wei, Weihua Gan, Aiqing Zhang, Xiaoyu Zhou, Bin Wang, Bi-Cheng Liu, Yuanyuan Ji

Get full text

Reducing Inequality through Parental Support: Building Social Resilience in Indonesia’s Indigenous Religious Communities by Novianti Wiwik, Noegroho Agoeng, Saputra Diki, Bunga Maharani Annisa, Lotulung Leviane J.H., Pinky Syalomita Kimberly, Desmiwati Desmiwati

“…By fostering pride in their faith, parents help their children build resilience, allowing them to maintain their religious identity in the face of societal challenges and negative external influences. …”
Get full text

Toll-like receptors in atopic dermatitis: pathogenesis and therapeutic implications by Ahmad Vafaeian, Fateme Rajabi, Nima Rezaei

Get full text

Neuroprotective role of epigallocatechin-3-gallate, albeginin and melanoxetin in alzheimer's disease by Arif Malik, Mehreen Hassan, Sulayman Waquar, Muhammad Wasim, Anam Naz, Faryal M. Awan, Muhammad T. Khan, Ali I. Khawaja, Sumera Zaib, Jamshed Iqbal, Ayesha Zahid, Marvi Marvi, Javeid Iqbal, Heng Wang, Dong-Qing Wei

Get full text

Candida albicans mannans mediate Streptococcus mutans exoenzyme GtfB binding to modulate cross-kingdom biofilm development in vivo. by Geelsu Hwang, Yuan Liu, Dongyeop Kim, Yong Li, Damian J Krysan, Hyun Koo

“…Candida albicans is frequently detected with heavy infection by Streptococcus mutans in plaque-biofilms from children with early-childhood caries (ECC). This cross-kingdom biofilm contains an extensive matrix of extracellular α-glucans that is produced by an exoenzyme (GtfB) secreted by S. mutans. …”
Get full text

Traditional games as a tool for improving psychosocial development: a comparative study of structured and progressive learning models by Rekha Ratri Julianti, Adang Suherman, Amung Ma'mun, Dian Budiana, Eka Fitri Novita Sari

“… Background: Pressure in the school environment, academic demands, and high social expectations often increase the vulnerability of children and adolescents to psychosocial problems. …”
Get full text

Barriers to accessing mental health services for women with perinatal mental illness: systematic review and meta-synthesis of qualitative studies in the UK by Megan Sambrook Smith, Vanessa Lawrence, Euan Sadler, Abigail Easter

Get full text

Ecological drivers of evolution of swine influenza in the United States: a review by Varun Goel, Jessica Ding, Bijaya Hatuwal, Emily Giri, Thomas J. Deliberto, James Lowe, Richard Webby, Michael Emch, Xiu-Feng Wan

Get full text

Targeting p62 by sulforaphane promotes autolysosomal degradation of SLC7A11, inducing ferroptosis for osteosarcoma treatment by Qiuming Zou, Xiaofeng Zhou, Jianqin Lai, Haixia Zhou, Jinxuan Su, Zhijing Zhang, Xiaosong Zhuang, Lili Liu, Ruijie Yuan, Sijia Li, Siyu Yang, Xinyi Qu, Jiezhu Feng, Yongqi Liu, Zisheng Li, Shiting Huang, Zhi Shi, Yu Yan, Zhiming Zheng, Wencai Ye, Qi Qi

“…Osteosarcoma (OS) is the most prevalent malignant bone tumor in children and adolescents worldwide. Identification of novel therapeutic targets and development of targeted drugs are one of the most feasible strategies for OS treatment. …”
Get full text

MYSM1 attenuates osteoarthritis by recruiting PP2A to deubiquitinate and dephosphorylate RIPK2 by Kang Wei, Chuankun Zhou, Zixing Shu, Xingru Shang, Yi Zou, Wei Zhou, Huanhuan Xu, Yulin Liang, Tian Ma, Xuying Sun, Jun Xiao

Get full text

Epsin3 promotes non-small cell lung cancer progression via modulating EGFR stability by Huiling Su, Jie Shen, Chenzi Gao, Yue Zhao, Wanyu Deng, Bo Qin, Xin Zhang, Juan Lai, Qian Wang, Jie Dou, Min Guo

Get full text

Increased Body Mass Index during Therapy for Childhood Acute Lymphoblastic Leukemia: A Significant and Underestimated Complication by Helen C. Atkinson, Julie A. Marsh, Shoshana R. Rath, Rishi S. Kotecha, Hazel Gough, Mandy Taylor, Thomas Walwyn, Nicholas G. Gottardo, Catherine H. Cole, Catherine S. Choong

“…We undertook a retrospective review of children diagnosed with acute lymphoblastic leukemia (ALL) and treated with modern COG protocols (n=80) to determine longitudinal changes in body mass index (BMI) and the prevalence of obesity compared with a healthy reference population. …”
Get full text

The mental health impact of COVID-19: the need for community interventions and collaboration for recovery by Nadarajah Rajeshkannan, Daya Somasundaram, Balachandran Kumarendran, Thirunavukarasu Kumanan, Ivan Dinesh Aloysius, Nalayini Sugirthan, Sivanantham Sasikumar, Nalayini Jegathesan

“…Family relationships and interactions generally improved but in a minority had strained dynamics. …”
Get full text

Identifying Zoonotic Parasites in Domiciled and Non‐Domiciled Dogs (Canis lupus familiaris) Within an Urban Zone of the Eastern State of Mexico by José Salcedo‐Jiménez, Yazmín Alcala‐Canto, Julio Segura‐Tinoco, Ernestina Valadez‐Moctezuma, Juan José Pérez‐Rivero

“…These dogs can act as carriers of zoonotic pathogens, placing children and individuals with chronic diseases or immunodeficiencies at risk. …”
Get full text

Improving Individualized Salbutamol Treatment: A Population Pharmacokinetic Model for Oral Salbutamol in Virtual Patients by Lara Marques, Nuno Vale

“…Conclusions: Despite current contraindications for oral salbutamol, our findings suggest that certain individuals, particularly children, may benefit from oral treatment over inhalation. …”
Get full text