Development and characterization of orthotopic patient-derived xenograft models of peritoneal metastatic mucinous appendiceal adenocarcinoma by I. Ito, V.K. Pattalachinti, A.M.G. Yousef, S. Chowdhury, M.M. Fanaeian, E. Haque, B.B. Gunes, M. Yousef, E.R. Salle, M.A. Zeineddine, S. Ji, R. Li, W. Wang, B.A. Helmink, M.W. Taggart, M.G. White, K.F. Fournier, N.W. Fowlkes, J.P. Shen

“…The lack of preclinical models of AA has hindered drug development and is a major factor in why AA remains without a single Food and Drug Administration-approved systemic treatment. …”
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Heterogeneous phenotype of a Chinese Familial WHIM syndrome with CXCR4V340fs gain-of-function mutation by Yu Huang, Yu Huang, Yu Huang, Lu Li, Lu Li, Ran Chen, Ran Chen, Lang Yu, Lang Yu, Shunkai Zhao, Yanjun Jia, Yanjun Jia, Ying Dou, Ying Dou, Ying Dou, Zhiyong Zhang, Zhiyong Zhang, Yunfei An, Yunfei An, Xuemei Tang, Xuemei Tang, Xiaodong Zhao, Xiaodong Zhao, Lina Zhou

“…It is caused mainly by heterozygous mutations at the C-terminus of the C-X-C chemokine receptor type 4 (CXCR4) gene.MethodsWe described the detailed clinical, genetic, immunological and treatment characteristic of four WHIM patients from a single Chinese family.ResultsHere, we report four patients from a family carrying a variant of CXCR4 (c.1016_1017dupCT), which introduces a frameshift at codon V340, resulting in an extension of 14 amino acids (p.V340L fs*27). …”
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E. Coli cytotoxic necrotizing factor-1 promotes colorectal carcinogenesis by causing oxidative stress, DNA damage and intestinal permeability alteration by Michela Tozzi, Alessia Fiore, Sara Travaglione, Francesca Marcon, Gabriella Rainaldi, Elena Angela Pia Germinario, Ilenia Laterza, Simona Donati, Daniele Macchia, Massimo Spada, Omar Leoni, Maria Cristina Quattrini, Donatella Pietraforte, Sofia Tomasoni, Filippo Torrigiani, Ranieri Verin, Paola Matarrese, Lucrezia Gambardella, Francesca Spadaro, Maria Carollo, Agostina Pietrantoni, Francesca Carlini, Concetta Panebianco, Valerio Pazienza, Filomena Colella, Donatella Lucchetti, Alessandro Sgambato, Antonella Sistigu, Federica Moschella, Marco Guidotti, Olimpia Vincentini, Zaira Maroccia, Mauro Biffoni, Roberta De Angelis, Laura Bracci, Alessia Fabbri

“…Methods Viability assays, confocal microscopy of γH2AX and 53BP1 molecules and cytogenetic analysis were carried out to assess CNF1-induced genotoxicity on non-neoplastic intestinal epithelial cells. …”
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Is it Time to Recognize Political Anxiety as a Social Determinant of Health? by Brandon Ambrosino

“…Of course, mentioning politics in clinical settings, especially to patients who seem all too eager to discuss them, carries a certain risk. …”
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Design and Research of Thrust Bearing for Datengxia Hydro-generator by GE Liangcheng, FAN Xiaofu, LUO Haiqiang, WU Zhongde, LIU Pingan

“…The thrust bearing is cooled by internal circulation, and the circulation of oil in the oil tank is carried out according to the set path in order to ensure the cooling efficiency and achieve the designed cooling effect. …”
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Pengaruh Media Pendingin pada Perlakuan Panas T6 terhadap Kekuatan Tarik dan Struktur Mikro Komposit Al6061-Pasir pantai by Hafidh Rawi Mufti, Hammar Ilham Akbar, Eko Surojo, Wibowo Wibowo, Teguh Triyono, Sukmaji Indro Cahyono, Nurul Muhayat, Triyono Triyono

“…The difference in quenching agents resulted in different cooling rates. After quenching, an artificial aging process was carried out at a temperature of 200 ^oC for 4 hours. …”
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Effect of pack carburizing and viscosity of quenching media on AISI 1010 steel by Agris Setiawan, Anggar Dipogusti

“…The material was then cooled slowly in the oven to a temperatur of 150oC which was then followed by air cooling. …”
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Dipendenza e sovranità alimentare nelle isole d’Oceania: voci di contrasto al gastro-colonialismo by Gaia Cottino

“…After discussing the process of gastronomic colonization carried out in liquid continent – began with the Europeans, carried on as a domination instrument and continued according to indirect forms of exercise of power – in order to draw common traits to the history of the edible foodscape of Oceania, the article proposes an analysis of those artistic productions denouncing the foodscape colonization. …”
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Measurements of Group Delay and Chromatic Dispersion of Hollow-Core Fiber Using a Frequency Domain Method by Xin Chen, Jason E. Hurley, John L. Nord, Ilia Nikulin, Paulo Dainese, Michael Sauer, Ming-Jun Li

“…Although hollow-core fibers are intended to be single-mode, they can potentially carry slightly higher-order mode content depending on the specific fiber structure. …”
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Structure and properties forming in ductile iron during isothermal hardening using ultrasound by M. S. Kovalko, A. T. Volochko, A. V. Ziziko, V. V. Rubanik

“…The mechanical properties and structure of the treated cast irons were determined both in the cast state and after isothermal quenching.To study the effect of ultrasonic treatment of the quenching bath on the formation of the structure and properties of highstrength cast irons during isothermal quenching, a number of comparative experiments were carried out, consisting in cooling the samples from 910 °C to 350 °C with and without the use of dynamic waves to the bath. …”
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INTERRELATION OF RHOMBICITY AND OCCURRENCE OF INTERNAL CRACKS AT CONTINUOUS CASTING OF SORTED SLUG by Ju. A. Samojlovich, V. I. Timoshpolski, S. M. Kabishov, R. B. Vajs

“…Analysis of deformations and stresses in cross section of sorted uninterruptedly-casted slugs at their solidification and cooling within limits of crystallizer with the aim of determination of possibilities for occurrence of internal cracks of diagonal type is carried out on basis of mathematical modeling, the peculiarities of the slug skin cooling at its shrinkage and separation from crystallizer wall are revealed.…”
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Severe Accident Simulation of the Laguna Verde Nuclear Power Plant by Gilberto Espinosa-Paredes, Raúl Camargo-Camargo, Alejandro Nuñez-Carrera

“…The LVNPP model was developed using RELAP/SCDAPSIM code. The lack of cooling water after the LOCA gets to the LVNPP to melting of the core that exceeds the design basis of the nuclear power plant (NPP) sufficiently to cause failure of structures, materials, and systems that are needed to ensure proper cooling of the reactor core by normal means. …”
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ORGANOLEPTIC AND PHYSICOCHEMICAL CHARACTERISTICS OF CONVENTIONAL AND MICROWAVE PROCESSING OF SATAY KOMOH FROM MEAT OF THUNNUS SP. STORED FROZEN AT VARIOUS MEAT DONENESS by Hardoko, Djamaludin H., Tristany B.J.

“…The aim of this study to determine the right conditions for processed satay meat that can be stored frozen. The research method applied was an experimental method carried out in the form of treating raw satay conditions, semi-cooked satay conditions, and cooked satay conditions stored frozen. …”
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Efficiency of lithium bromide absorption chiller with multi-stage absorption and generation processes with associated mass flow by O. S. Malinina, A. V. Baranenko, M. A. Al-Furaiji, E. E. Lydova, K. A. Komarov

“…A comparative analysis of the cycle understudy with the sample cycle (one-stage cycle) LBWAC is carried out. Despite the lower values of the coefficient of performance (COP), the cycle under study provides a doubling of the cooling capacity of the machine, at the same flow rate of the heating source, which is an advantage when the flow rate of the heating source is limited. …”
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Effects of Thermodynamics on the Concurrent Accretion and Migration of Gas Giants in Protoplanetary Disks by Hening Wu, Ya-Ping Li

“…The thermodynamics effect is modeled with a thermal relaxation timescale using a <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mi>β</mi></semantics></math></inline-formula>-cooling prescription. Our results indicate that radiative cooling has a substantial effect on the accretion and migration processes of the planet. …”
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INVESTIGATION OF INFLUENCE OF REGIMES OF THERMAL PROCESSING ON STRUCTURE AND MECHANICAL CHARACTERISTICS OF HOT-ROLLED TUBES, PRODUCED OF STEEL 32G2 by V. V. Ivashko, O. M. Kirilenko, I. I. Vegera, D. A. Semjonov

“…Investigations on influence of heating temperature, cooling regimes and steady temperature on structure and mechanical characteristics of hot-rolled pipes, produced of steel 32G2, are carried out.…”
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Influence of Quenching Agents on Mechanical, Wear, and Fracture Characteristics of Al2O3 / MoS2 Reinforced Al-6061 Hybrid Metal Matrix Composite (MMCs) by K. R. Suchendra, M. Sreenivasa Reddy, M. Ravikumar

“…Finally, age-hardening was done at 180ºC temperature for 4 hours and then the samples were cooled under room temperature. Heat treated hybrid composites were subjected to evaluate the hardness, tensile, and wear behavior. …”
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Residual Strain Monitoring and Dynamic Characteristics of Hybrid Hollow Square Tube with Metal–FRP–Metal Sandwich Walls by Zhao Li, Mingyao Liu, Jintao Wang, Wei Ke

“…The results showed that the damping of the hybrid HST is 586% higher than that of the steel HST, while the hybrid HST has a lower first natural frequency (4.6% reduction) and mass (15.9% weight reduction). The influence of co-cure temperature and cooling rate on the size and state of the residual strains is analyzed, which might be helpful to guide the manufacturing of sandwich structures in machine tools. …”
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Very high cycle fatigue strength and crack growth of thin steel sheets by Mohand Ouarabi, Ruben Perez Mora, Claude Bathias, Thierry Palin-Luc

“…The crack initiation tests were carried out with water cooling, while the crack growth test were carried out in laboratory air at room temperature. …”
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Effect of adding concentrated myofibrillar proteins of silver carp (Hypophthalmichthys molitrix) on the qualitative and nutritional characteristics of pasta by Mahsa Karami Charvadeh, Eshagh Zakipour Rahimabadi, Parva Safari

“…In addition, the swelling index showed an increasing trend, displaying the effect of concentrated myofibrillar protein on the elevated water absorption rate and water retention capacity during the cooking processes. Conclusion: Given the results of sensory analysis with chemical characteristics and quality characteristics of cooking the pasta, it can be concluded that enrichment with up to 10% concentrated myofibrillar fish proteins makes no difference compared to the control group, while enhancing the desired characteristics of the final product.…”
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