A SARS‐CoV‐2 EG.5 mRNA vaccine induces a broad‐spectrum immune response in mice by Hongyu Wang, Qinhua Peng, Xinxian Dai, Zhifang Ying, Xiaohong Wu, Xinyu Liu, Hongshan Xu, Jia Li, Leitai Shi, Jingjing Liu, Yunpeng Wang, Danhua Zhao, Yanqiu Huang, Lihong Yang, Ren Yang, Guangzhi Yue, Yue Suo, Qiang Ye, Shouchun Cao, Yuhua Li

“…Th1‐biased cellular immune response was induced in all vaccination groups. The antigen design and immunization strategy of this study have reference significance for the research of the next generation of COVID‐19 vaccine and other vaccines.…”
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Computational design, expression, and characterization of a Plasmodium falciparum multi-epitope, multi-stage vaccine candidate (PfCTMAG) by Joan A. Chick, Nadege N. Abongdia, Robert A. Shey, Tobias O. Apinjoh

“…In sero-reactivity studies, malaria-positives (cases) had higher anti-PfCTMAG IgG (p = 0.024) and IgM (p < 0.001) levels compared to malaria negatives (controls). …”
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Posttranscriptional Suppression of Lipopolysaccharide-Stimulated Inflammatory Responses by Macrophages in Middle-Aged Mice: A Possible Role for Eukaryotic Initiation Factor 2α by Ken Shirato, Kazuhiko Imaizumi

“…Peritoneal macrophages isolated from 2-month-old (young) and 12-month-old (middle-aged) male BALB/c mice were stimulated with lipopolysaccharide (LPS). …”
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PET imaging of AAV9 and AAVBR1 trafficking in normal mice by Aditya Bansal, Shalini Sharma, Manasa Kethamreddy, Mukesh K. Pandey

“…The 89Zr radiolabeled AAVs were administered to BALB/c mice via tail vein and assessed for their biodistribution at various time points up to day 18 post-injection. …”
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Fusion to Flaviviral Leader Peptide Targets HIV-1 Reverse Transcriptase for Secretion and Reduces Its Enzymatic Activity and Ability to Induce Oxidative Stress but Has No Major Eff... by Anastasia Latanova, Stefan Petkov, Yulia Kuzmenko, Athina Kilpeläinen, Alexander Ivanov, Olga Smirnova, Olga Krotova, Sergey Korolev, Jorma Hinkula, Vadim Karpov, Maria Isaguliants, Elizaveta Starodubova

“…Promotion of secretion prohibited proteasomal degradation increasing the half-life and content of RT1.14oil in cells and cell culture medium, drastically reduced the residual polymerase activity, and downmodulated oxidative stress. …”
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Jet Injection of Naked mRNA Encoding the RBD of the SARS-CoV-2 Spike Protein Induces a High Level of a Specific Immune Response in Mice by Denis N. Kisakov, Larisa I. Karpenko, Lyubov A. Kisakova, Sergey V. Sharabrin, Mariya B. Borgoyakova, Ekaterina V. Starostina, Oleg S. Taranov, Elena K. Ivleva, Oleg V. Pyankov, Anna V. Zaykovskaya, Elena V. Dmitrienko, Vladimir A. Yakovlev, Elena V. Tigeeva, Irina Alekseevna Bauer, Svetlana I. Krasnikova, Nadezhda B. Rudometova, Andrey P. Rudometov, Artemiy A. Sergeev, Alexander A. Ilyichev

“…Then, we used the selected protocol to immunize BALB/c mice with mRNA-RBD encoding the SARS-CoV-2 receptor-binding domain (RBD). …”
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Essential Roles of PKA, iNOS, CD95/CD95L, and Terminal Caspases in Suppression of Eosinopoiesis by PGE2 and Other cAMP-Elevating Agents by Bianca de Luca, Pedro Xavier-Elsas, Mônica Barradas, Ricardo A. Luz, Túlio Queto, Carla Jones, Maria Augusta Arruda, Thiago Mattar Cunha, Fernando Queiroz Cunha, Maria Ignez Gaspar-Elsas

“…Bone-marrow collected from BALB/c mice, or from iNOS-, CD95-, or CD95L-deficient mutants (and wild-type controls), was cultured with interleukin-5 (IL-5), alone or associated with PGE2, cAMP-inducing/mimetic agents, caspase inhibitor zVAD-fmk, iNOS inhibitor aminoguanidine, or combinations thereof, and eosinopoiesis was evaluated at various times. …”
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Regulation of IL-33 by Oncostatin M in Mouse Lung Epithelial Cells by Carl D. Richards, Laura Izakelian, Anisha Dubey, Grace Zhang, Steven Wong, Karen Kwofie, Aatif Qureshi, Fernando Botelho

“…Although IL-33 expression can be altered upon NF-Kappa B activation, here we examine regulation by Oncostatin M, a gp130 cytokine family member, in mouse lung tissue. …”
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Characterizing microbial communities and their correlation with genetic mutations in early-stage lung adenocarcinoma: implications for disease progression and therapeutic targets by Hao-Shuai Yang, Jin Zhang, Hong-Xiang Feng, Fei Qi, Fan-Jia Kong, Wei-Jie Zhu, Chao-Yang Liang, Zhen-Rong Zhang

“…Intratumoral microbiota may play a role in LUAD progression, but comprehensive stage-wise analysis is lacking.MethodsTumor and bronchoalveolar lavage fluid (BALF) samples from patients with AIS/MIA or IAC were collected for next-generation sequencing to characterize microbial diversity and composition. …”
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Modelo para la asignación de terrenos en el marco de la Reforma Rural Integral by Karen Rocío Martínez Lancheros, Natalia Quintero Avellaneda, Yony Fernando Ceballos

“…Los resultados incluyen dos escenarios de aplicaciÛn con diferentes mÈtricas de valoraciÛn de proyectos productivos, en los cuales se evidencia la forma en la cual podrÌan ser asignados los predios baldÌos en la zona del oriente del departamento de Antioquia, Colombia.…”
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饮食抗原对IgA肾病产生的影响

“…本研究探讨抗原刺激粘膜免疫及封闭网状内皮系统与ＩｇＡ于肾小球系膜沉积的关系实验用８－１０周ＢＡＬＢ／ｃ雌性小鼠６０只，分别口服饮食抗原（麦胶蛋白和牛－γ球蛋白），并于实验开始后前３周用或不用印度墨水尾静脉注射。…”
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Resin-Modified Glass Ionomer Nanocomposite: Subcutaneous Connective Tissue Response and Polymerization Shrinkage Resistance by Edélcio Garcia-Júnior, Beatriz Kelly Barros Lopes, Fabricio Kitazono de Carvalho, Raquel Assed Bezerra da Silva, Fernanda de Carvalho Panzeri Pires de Souza, Alberto Consolaro, Lea Assed Bezerra da Silva, Paulo Nelson-Filho

“…Material and Methods: A total of 90 isogenic BALB/c mice were randomly distributed into nine groups, with each group receiving an implant of one of the following materials: ChemFil, Ketac N100, Compoglass, and Filtek Z350, as well as empty tubes serving as controls. …”
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Microclimates growing and watering volumes influences the physiological traits of chili pepper cultivars in combating abiotic stress by Farhan Ahmad, Kusumiyati Kusumiyati, Mochamad Arief Soleh, Muhammad Rabnawaz Khan, Ristina Siti Sundari

“…One of the world’s largest chili consumers, Indonesia faces climate adversities and cash-crop pest infestations that affect its horticulture market. …”
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Early neutrophil activation and NETs release in the pristane-induced lupus mice model. by Solange Carrasco, Bernadete L Liphaus, Tatiana Vasconcelos Peixoto, Thais Martins Lima, Sueli Kunimi Kubo Ariga, Zelita Aparecida Jesus Queiroz, Thays de Matos Lobo, Sergio Catanozi, Letícia Gomes Rodrigues, Antônio Santos Filho, Walcy Rosolia Teodoro, Ana Paula Pereira Velosa, Débora Levy, Francisco Garcia Soriano, Cláudia Goldenstein-Schainberg

“…<h4>Results</h4>The pristane-induced mice group had a significantly increased number of blood activated neutrophils and LDGs as well as NETs released by these cells compared to the saline-injected control group and the basal values determined 12 days before the injection. …”
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The Anticonvulsant Enaminone E139 Attenuates Paclitaxel-Induced Neuropathic Pain in Rodents by Dhandapani Thangamani, Ivan Ogheneochuko Edafiogho, Willias Masocha

“…The reaction latency to thermal stimuli (hot-plate test) of BALB/c mice was recorded before and after intraperitoneal treatment with paclitaxel (2 mg/kg, i.p. for 5 consecutive days), and after treatment with E139 (0.1–40 mg/kg), amitriptyline (10 mg/kg), and gabapentin (10 and 30 mg/kg). …”
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Pyrroloquinoline Quinone Administration Alleviates Allergic Airway Inflammation in Mice by Regulating the JAK-STAT Signaling Pathway by Zhihui Min, Jiebai Zhou, Ruolin Mao, Bo Cui, Yunfeng Cheng, Zhihong Chen

“…Treatment with PQQ significantly reduced bronchoalveolar lavage fluid (BALF) inflammatory cell counts in the OVA-induced mouse model. …”
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Exploration of the anti-inflammatory potential of Polygonum bistorta L.: protection against LPS-induced acute lung injury in rats via NF-ĸβ pathway inhibition by Sajida Parveen, Kashif ur Rehman Khan, Shahid Muhammad Iqbal, Hanan Y. Aati, Areej M. Al-taweel, Liaqat Hussain, Musaddique Hussain, Musaddique Hussain

“…In conclusion, P. bistorta roots mitigate inflammation and oxidative stress by improving redox signaling and NF-ĸβ (p65) pathways and can thus play a role in strategies for overcoming therapeutic challenges.…”
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Construction Time of Three Wall Types Made of Locally Sourced Materials: A Comparative Study by Wojciech Drozd, Agnieszka Leśniak, Sebastian Zaworski

“…Three types of walls made of locally sourced materials were studied: a wall made of clay blocks insulated with mineral wool boards, a wall made of clay compacted in formwork, and one insulated with mineral wool boards and wooden frame structure filled with straw bales and cladded with fibreboards. …”
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Fertility, gestation outcome and parasite congenital transmissibility in mice infected with TcI, TcII and TcVI genotypes of Trypanosoma cruzi. by Sabrina Cencig, Nicolas Coltel, Carine Truyens, Yves Carlier

“…This work aims to compare the effects of acute or chronic infections with the T. cruzi genotypes TcI (X10 strain), TcII (Y strain) and TcVI (Tulahuen strain) on fertility, gestation, pup growth and the possible vertical transmission of parasites in BALB/c mice. The occurrence of congenital infection was evaluated by microscopic examination of blood and/or qPCR on blood and heart in newborn pups and/or older offspring submitted to cyclophosphamide-induced immunosuppression in order to detect possible cryptic congenital infection. …”
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Relapse detection in the Danish surveillance program of patients with clinical stage I seminoma: a nationwide study by Niklas B. Lindahl, Jakob Lauritsen, Thomas Wagner, Gedske Daugaard, Mikkel Bandak

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