Identification of an immunological signature of long COVID syndrome by Gisella Guerrera, Manolo Sambucci, Eleonora Timperi, Mario Picozza, Andrea Misiti, Andrea Misiti, Roberta Placido, Silvia Corbisiero, Silvia D’Orso, Andrea Termine, Carlo Fabrizio, Francesca Gargano, Sharon Eleuteri, Luisa Marchioni, Veronica Bordoni, Luigi Coppola, Marco Iannetta, Chiara Agrati, Giovanna Borsellino, Luca Battistini

“…Through BGLM, a unique adaptive immune signature for LC was identified, featuring memory CD8 and gd T cells with low proliferative capacity and diminished expression of activation and homing receptors.DiscussionThe findings highlight a unique immunological signature associated with LC syndrome, characterized by persistent adaptive immune dysregulation. …”
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Does a complex intervention targeting communities, health facilities and district health managers increase the utilisation of community-based child health services? A before and af... by Joanna Schellenberg, Della Berhanu, Lars Åke Persson, Muluemebet Abera Wordofa, Araya Abrha Medhanyie, Fisseha Ashebir Gebregizabher, Habtamu Beyene, Ephrem Tekle Lemango, Abebe Bekele, Theodros Getachew, Mezgebu Yitayal, Yemisrach Behailu Okwaraji, Atkure Defar, Fitsum W/Gebriel, Alem Desta, Dawit Wolde Daka, Alemayehu Hunduma, Tigist Getahun, Amare Tariku Woldemariam, Desta Wolassa

“…Optimising the Health Extension Programme was a 2-year intervention in 26 districts, focusing on community engagement, capacity strengthening of primary care workers and reinforcement of district accountability of child health services. …”
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Quantitative proteomics and targeted metabolomics reveal the role of Cassia siamea L. extract in the response to high-fat diet-induced obesity in Drosophila by Ananya Dechakhamphu, Nattapong Wongchum, Theeraphan Chumroenphat, Alongklod Tanomtong, Sirithon Siriamornpun

“…Additionally, CSE increased survival rates, physical strength, and antioxidant capacity, as evidenced by increased SOD1 activity and resistance to oxidative stress. …”
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Correlations among fatigue, respiratory function, balance and core muscle morphology in multiple sclerosis: a comprehensive observational study by Marta De La Plaza San Frutos, Ismael Sanz-Esteban, Ismael Sanz-Esteban, Federico Salniccia, Federico Salniccia, Alberto Bermejo-Franco, Alberto Bermejo-Franco, Ameyalli García-Corona, María Cristina Palma-Baquedano, Marina Castel-Sánchez, Marina Castel-Sánchez, Cecilia Estrada-Barranco, Cecilia Estrada-Barranco

“…Study variables were: fatigue (Modified Fatigue Impact Scale—MFIS); respiratory function (Forced Vital Capacity—FVC and Forced Expiratory Volume in the first second—FEV1); balance (Berg Balance Scale—BBS and Trunk Impairment Scale Dynamic—TIS DYN); and ultrasound measurements of abdominal and diaphragmatic musculature. …”
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Evolution within a given virulence phenotype (pathotype) is driven by changes in aggressiveness: a case study of French wheat leaf rust populations by Fontyn, Cécilia, Meyer, Kevin JG, Boixel, Anne-Lise, Delestre, Ghislain, Piaget, Emma, Picard, Corentin, Suffert, Frédéric, Marcel, Thierry C, Goyeau, Henriette

“…We assessed three components of aggressiveness — infection efficiency, latency period and sporulation capacity — for 44 isolates representative of the four P. triticina pathotype-genotype combinations. …”
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Una nueva estrategia integral para modelar materiales urbanos para ciudades térmicamente habitables. Un caso de estudio en Madrid = A new integrated strategy for modelling urban ma... by Emanuela Giancola, Helena López, Silvia Soutullo, M. Nuria Sánchez, Luis F. Zarzalejo, Ana Gamarra, Israel Herrera, J. Antonio Ferrer, Emanuele Naboni

“…Por estas razones, es necesario crear flujos de trabajo basados en simulaciones ad-hoc capaces de evaluar la influencia de los materiales y sus impactos en ambientes exteriores e interiores. …”
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Lidar estimates of birch pollen number, mass, and CCN-related concentrations by M. Filioglou, P. Tiitta, P. Tiitta, X. Shang, A. Leskinen, P. Ahola, S. Pätsi, A. Saarto, V. Vakkari, V. Vakkari, U. Isopahkala, M. Komppula

“…In turn, this demonstrates the potential of ground-based lidars such as a ceilometer network with the polarization capacity to document large-scale birch pollen outbursts in detail and thus to provide valuable information for climate, cloud, and air quality modeling efforts, elucidating the role of pollen within the atmospheric system.…”
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Hypermethylation in Calca Promoter Inhibited ASC Osteogenic Differentiation in Rats with Type 2 Diabetic Mellitus by Lei Wang, Feng Ding, Shaojie Shi, Xingxing Wang, Sijia Zhang, Yingliang Song

“…This result provides an implication for us to understand the mechanism of the decreased osteogenic ability of ASCs-T2DM and improve its osteogenic capacity.…”
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DFT and molecular docking analyses of the effects of solvent polarity and temperature on the structural, electronic, and thermodynamic properties of p-coumaric acid: Insights for a... by Umer Sherefedin, Abebe Belay, Kusse Gudishe, Alemu Kebede, Alemayehu Getahun Kumela, Tadesse Lemma Wakjira, Dereje Gelanu, Tesfaye Feyise, Jebel Haji Mahamud, Abdulkerim Abdela, Kebede Shankute Gizew

“…The thermal analysis also revealed that increasing the temperature from 100 K to 1000 K led to higher enthalpy, heat capacity, and entropy, along with a decrease in Gibbs free energy values due to enhanced molecular vibrations, contributing to the degradation and instability of p-CA. …”
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Widespread trace bromine and iodine in remote tropospheric non-sea-salt aerosols by G. P. Schill, K. D. Froyd, K. D. Froyd, D. M. Murphy, C. J. Williamson, C. J. Williamson, C. A. Brock, T. Sherwen, M. J. Evans, M. J. Evans, E. A. Ray, E. A. Ray, E. C. Apel, R. S. Hornbrook, A. J. Hills, J. Peischl, J. Peischl, T. B. Ryerson, C. R. Thompson, I. Bourgeois, D. R. Blake, J. P. DiGangi, G. S. Diskin

“…<p>Reactive halogens catalytically destroy O<span class="inline-formula">₃</span> and therefore affect (1) stratospheric O<span class="inline-formula">₃</span> depletion and (2) the oxidative capacity of the troposphere. Reactive halogens also partition into the aerosol phase, but what governs halogen-aerosol partitioning is poorly constrained in models. …”
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Physicochemical Parameters, Mineral Composition, and Nutraceutical Properties of Ready-to-Drink Flavored-Colored Commercial Teas by Daniel Flores-Martínez, Vania Urías-Orona, Luis Hernández-García, Werner Rubio-Carrasco, Korev Silva-Gutiérrez, Michelle Guevara-Zambrano, Julio Prieto-Cadena, Teresa Serna-Méndez, Dolores Muy-Rangel, Guillermo Niño-Medina

“…Lemon- and rose petal-flavored teas showed the highest and lowest antioxidant capacity levels in DPPH (1096.00 to 118.77 μmolTE·L−1), ABTS (1048.84 to 232.00 μmolTE·L−1), and FRAP (1269.20 to 147.70 μmolTE·L−1) assays. …”
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Global decadal measurements of methanol, ethene, ethyne, and HCN from the Cross-track Infrared Sounder by K. C. Wells, D. B. Millet, J. F. Brewer, V. H. Payne, K. E. Cady-Pereira, R. Pernak, S. Kulawik, S. Kulawik, C. Vigouroux, N. Jones, E. Mahieu, M. Makarova, T. Nagahama, I. Ortega, M. Palm, K. Strong, M. Schneider, D. Smale, R. Sussmann, M. Zhou

“…<p>Volatile organic compounds (VOCs) play an important role in modulating the atmosphere's oxidizing capacity and affect tropospheric ozone, carbon monoxide, formaldehyde, and organic aerosol formation. …”
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Mapping an evidence-based end-of-life care framework for older adults in Chinese nursing homes: protocol for a scoping review by Yuanyuan Zhao, Boon How Chew, Yuehua Tu, Eva Marie Gacasan

“…The data extraction process will be guided by the Canadian Hospice Palliative Care Association model (CHPCA) and the Respectful Death model. Qualitative data analysis will be performed using a framework method and thematic analysis, employing both inductive and deductive approaches, with three reviewers participating in the review process.Ethics and dissemination Ethical approval is not required because the data for this review is obtained from selected publicly available articles. …”
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Molecular investigation reveals three hemotropic mycoplasmas in cats and three tick species in China by Hongfei Shi, Guoguang Li, Dandan Li, Hongyue Zhai, Shidong Ji, Yun Hu, Long Wang, Lunguang Yao

“…Additionally, these three hemotropic mycoplasmas were also found in three species of ticks, and transmission experiments are required to investigate the capacity of these ticks to transmit hemoplasmas Mycoplasma among animals.…”
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Characteristics and contributing factors of adverse drug reactions: an analytical study of patients with tuberculosis receiving treatment under the National TB Program of India [ve... by Jay Patel, Priya Bhavsar, Harsh Shah, Sandul Yasobant, Deepak Saxena, Anish Sinha, Somen Saha, Yogesh Patel

“…Conclusion The study highlighted a need to enhance health care providers’ capacity and program structure for managing ADRs among TB patients. …”
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The effectiveness and risks of Treating people with Idiopathic Pulmonary fibrosis with the Addition of Lansoprazole (TIPAL): study protocol for a randomised placebo-controlled mult... by Toby M Maher, A John Simpson, Anthony Cahn, David Thickett, Luke Vale, Allan B Clark, Nazia Chaudhuri, Ian Forrest, Lisa G Spencer, Christopher Ward, Stephen Jones, Ganesh Raghu, Andrew M Wilson, Helen Parfrey, Megan Jones, Matthew Hammond, Jaclyn Ann Smith, Shajahan Wahed

“…We aim to undertake an adequately powered double-blind placebo-controlled randomised multicentre clinical trial to assess the change in forced vital capacity (FVC), cough and other important patient-reported outcomes, following 12-month therapy with PPIs in people with IPF.Methods and analysis A total of 298 patients with IPF diagnosed by a multidisciplinary team according to international guidelines who are not receiving PPIs will be enrolled. …”
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Construction and Validation of a Major Depression Risk Predictive Model for Patients with Coronary Heart Disease: Insights from NHANES 2005–2018 by Li-xiang Zhang, Shan-bing Hou, Fang-fang Zhao, Ting-ting Wang, Ying Jiang, Xiao-juan Zhou, Jiao-yu Cao

“…Multivariate weighted logistic regression revealed that waist circumference, smoking status, arthritis, sleep disorders, and restricted work capacity were independent risk factors for major depression (odds ratio (OR) >1, p < 0.05). …”
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Gait spatiotemporal alterations in schoolchildren with overweight or obesity: a cross-sectional study by José Omar Larios-Tinoco, Xochiquetzalli Tejeda-Castellanos, Carlos Maximiliano Sánchez-Medina, Ma. Elena Ortiz-Cornejo, Horacio Márquez-González, María de Lourdes Martín-López, Salvador Villalpando-Carrión, Claudia Gutiérrez-Camacho, José Luis Alaniz-Arcos

“…Abstract Background Alterations in spatiotemporal parameters during walking modify and limit movement capacity in children with obesity. This study aimed to describe and compare the alterations in spatiotemporal parameters in schoolchildren according to body weight during all phases of walking. …”
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Effects of Artificial Compound Feed for Live Fish Feed on Growth Performance, Nutrient Composition, Digestive Performance, and Gut Microbiota of Giant Salamander (<i>Andrias davidi... by Hongxiang Fan, Peiying Huang, Jiayi Zhu, Jiamin Li, Shaoqing Jian, Jiahao Hou, Ziyu Wang, Linjie Li, Daxian Zhao

“…In conclusion, replacing live feed with artificial compound feed does not affect the growth performance, nutritional composition, antioxidant capacity, and digestive function of Chinese giant salamander juveniles. …”
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Lung function improvement on triple modulators: high-resolution, nationwide data from the Danish Cystic Fibrosis Cohort by Christian Leo-Hansen, Daniel Faurholt-Jepsen, Tavs Qvist, Christine Højte, Bibi U. Nielsen, Thomas Bryrup, Esben H. Henriksen, Terese Katzenstein, Marianne Skov, Inger H.M. Mathiesen, Majbritt Jeppesen, Søren Jensen-Fangel, Hanne V. Olesen, Frederik Fouirnaies Buchvald, Kim Gjerum Nielsen, Espen Jimenez-Solem, Christian Ritz, Tacjana Pressler, Mette F. Olsen, the TransformCF Study Group

“…Methods Data were analysed using linear mixed-effect models to assess changes in levels and annual rates of change (slopes) in percent predicted (pp) forced expiratory volume in 1 s (FEV1), forced vital capacity (FVC) and forced expiratory flow at 25–75% of FVC (ppFEF25–75%) between the 12 months pre-treatment and treatment periods. …”
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