Transcriptome analysis reveals hypoxic response key genes and modules as well as adaptive mechanism of crucian carp (Carassius auratus) gill under hypoxic stress by Mengchao Xing, Mengchao Xing, Zhen Rong, Zhen Rong, Xin Zhao, Xin Zhao, Xiaowei Gao, Xiaowei Gao, Zhiguang Hou, Lihan Zhang, Lihan Zhang, Waiho Khor, Yihuan Xu, Yihuan Xu, Li Chen, Li Chen, Chengbin Wu, Chengbin Wu

“…The VEGF pathway genes are significantly expressed, enhancing the generation of microvessels in the gill filaments, and improving the capacity to carry oxygen, thus enabling the crucian carp to adapt to hypoxia stress. …”
Get full text

Global Insights from Patients, Providers, and Staff on Challenges and Solutions in Managing Neovascular Age-Related Macular Degeneration by Anat Loewenstein, Michelle Sylvanowicz, Winfried M. Amoaku, Tariq Aslam, Chui Ming Gemmy Cheung, Bora Eldem, Robert P. Finger, Richard P. Gale, Laurent Kodjikian, Adrian Koh, Jean-François Korobelnik, Xiaofeng Lin, Paul Mitchell, Moira Murphy, Mali Okada, Ian Pearce, Francisco J. Rodriguez, Jude Stern, S. James Talks, David T. Wong, Tien Yin Wong, Focke Ziemssen, Jane Barratt

“…Addressing the opportunities raised could improve patient adherence to treatment and potentially outcomes, reduce appointment burden, and increase clinic capacity.…”
Get full text

Effects of Dietary Iron Levels on the Production Performance, Nutrient Digestibility, Blood Biochemistry, and Meat and Fur Quality of Growing Rex Rabbits by Jiali Chen, Jiyuan Wang, Lei Liu, Fuchang Li

“…Dietary Fe addition also significantly elevated serum concentrations of Fe and copper (<i>p</i> < 0.05) while decreasing the total Fe-binding capacity (<i>p</i> < 0.05). In conclusion, dietary Fe supplementation boosted growth performance, protein and nitrogen digestibility, Fe stores, and meat and fur quality in Rex rabbits. …”
Get full text

A miR-activated hydrogel for the delivery of a pro-chondrogenic microRNA-221 inhibitor as a minimally invasive therapeutic approach for articular cartilage repair by Shan An, Claudio Intini, Donagh O'Shea, James E. Dixon, Yiran Zheng, Fergal J. O'Brien

“…Articular cartilage has limited capacity for repair (or for regeneration) under pathological conditions, given its non-vascularized connective tissue structure and low cellular density. …”
Get full text

Evaluation of Expanded Clay and Tuff as Lightweight Agents in Concrete Stabilized with Nopal Mucilage and Aloe Vera by Daniel Mendoza-Goden, Rocio Rafaela Gallegos-Villela, Pedro Flores-Becerra, Josue Francisco Perez-Sanchez, Edgardo Jonathan Suarez-Dominguez, Arturo Palacio-Perez

“…To assess their performance, a series of physical tests (bulk density, water absorption, and slump), mechanical tests (compressive strength), and thermal characterizations (conductivity, heat capacity, and resistivity) were conducted. Fractal analysis was employed to evaluate the structural complexity of the mixtures. …”
Get full text

Heat Re-process approach and thermally integrated renewable energy system for power, compressed hydrogen, and freshwater production; ANN boosted optimization and techno-enviro-econ... by Zhaoyang Zuo, Junhua Wang, Mohammed A. Alghassab, Nashwan Adnan Othman, Ahmad Almadhor, Fahad M. Alhomayani, Hind Albalawi, Samah G. Babiker, Barno Abdullaeva, Aboulbaba Eladeb

“…A key innovation is using waste heat from the SCO2-BC to power an organic Rankine cycle (ORC), which improves the performance and power generation capacity of the proposed system. Additionally, the machine learning optimization technique is employed to optimize the system, significantly reducing computational costs and runtime for the optimization process. …”
Get full text

Influenza Immunization in Very-Low-Birth-Weight Infants: Epidemiology and Long-Term Outcomes by Marie-Theres Dammann, Hannah Kraft, Guido Stichtenoth, Kathrin Hanke, Michael Zemlin, Janina Soler Wenglein, Isabell Ricklefs, Alexander Herz, Alexander Humberg, Dorothee Viemann, Geraldine Engels, Matthias Volkmar Kopp, Folke Brinkmann, Carsten Fortmann-Grote, Wolfgang Göpel, Egbert Herting, Christoph Härtel, Ingmar Fortmann, on behalf of the German Neonatal Network

“…Conclusions: Influenza immunization was not associated with improved lung function (forced expiratory volume in one second and forced vital capacity) or a better neurocognitive outcome (intelligence quotient and strengths and difficulties questionnaire) at early school age. …”
Get full text

Iron⁃calcium⁃biochar enhanced sludge deep dewatering and sludge⁃based biochar preparation by JIAO Hongming, FU Liang*, ZHOU Yingying, WANG Xurong, ZHANG Leilei, Gao Yonglin, ZHOU Dandan

“…Notably, it showed remarkable efficiency in removing Cr6+, with an impressive adsorption capacity of 26.51 mg / g. This study has developed a comprehensive technical strategy to enhance the deep dewatering of difficult dewatering residual sludge and prepare high-performance sludge biochar, providing a valuable scientific basis and technical reference for the treatment and resource utilization of difficult dewatering residual sludge.…”
Get full text

The Influence of Ficus deltoidea in Preserving Alveolar Bone in Ovariectomized Rats by N. I. Omar, B. Baharin, S. F. Lau, N. Ibrahim, N. Mohd, A. Ahmad Fauzi, N. Muhammad, N. M. Fernandez

“…In conclusion, F. deltoidea has the capacity to prevent alveolar bone loss in ovariectomy-induced osteoporosis rats by potentially preserving trabecular bone microarchitecture and to decrease osteoclast and increase osteoblast cell count.…”
Get full text

Trends and factors associated with skilled birth attendance in a post-Ebola context: DHS Guinea 2018 by Madeleine Toure, Fanta Barry, Tiany Sidibe, Sadan Camara, Ramata Diallo, Kaba Saran Keita, Maimouna Balde, Bienvenu Salim Camara, Karifa Kourouma, Mamadou Dioulde Balde

“…Contribution: The interventions undertaken to strengthen the maternal health system in the aftermath of the Ebola epidemic should be reinforced and maintained, in particular the retention of health providers deployed in rural areas and capacity building (training, equipment) for community health workers would help to improve this indicator…”
Get full text

Rare Taxa Are Key Links in Regional Antimicrobial Resistance Profiles in Dusts Across Diverse North American Regions by Paul B. L. George, Florent Rossi, Marc Veillette, Amélia Bélanger Cayouette, Samantha Leclerc, Cindy Dumais, Nathalie Turgeon, Caroline Duchaine

“…Furthermore, this study highlights the potential application of vehicle air filters in building long‐term monitoring capacity of outdoor bioaerosols.…”
Get full text

Nomogram model using serum Club cell secretory protein 16 to predict prognosis and acute exacerbation in patients with idiopathic pulmonary fibrosis by Yaqiong Tian, Xuan Zhou, Mi Tian, Lijun Ren, Ruyi Zou, Hanyi Jiang, Miaomiao Xie, Mei Huang, Jingjing Ding, Yin Liu, Jingyu Chen, Min Cao, Hourong Cai

“…Results Serum CC16 gradually increased with the severity of fibrosis, and was especially high in AE-IPF group. CC16 and diffusion capacity for carbon monoxide (DLCO) were screened as characteristic variables to construct nomogram model for IPF prognosis. …”
Get full text

Toxicity effect of Ricinus communis methanolic extracts against Bactrocera cucurbitae (Diptera: Tephritidae) by Sadia Manzoor, Rasheed Akbar, Afaq Hussain, Amjad Ali, Brekhna Faheem, Maid Zaman, Abid Farid, Ijaz Hussain, Imtiaz Ali Khan, Kahkashan Perveen (ORCID:

“…The adaptability, high reproductive capacity, and broad host range of B. cucurbitae make it a persistent challenge for growers worldwide. …”
Get full text

Mechanical Properties and Failure Modes of Thick-Walled Cylinder Granites with Different Apertures under Triaxial Compression by Wei Chen, Wen Wan, Shuailong Lian, Senlin Xie, Yu Zhou, Wenqing Peng, Wenlong Kuang, Xianqing Wang, Shasha Tong

“…Under the same σ3, the value of m presents a decreasing trend from the outer wall to the inner wall, which means the bearing capacity keeps getting lower and lower. As a result, the inner wall is most likely to be damaged. …”
Get full text

Childhood lung function is associated with adolescent-onset and persistent asthma by Hans Jacob L. Koefoed, Anhar Ullah, Jenny Hallberg, Simon Kebede Merid, Maura M. Kere, Lesley Lowe, Angela Simpson, Clare S. Murray, Ulrike Gehring, Roel Vermeulen, Inger Kull, Anna Bergström, Judith M. Vonk, Adnan Custovic, Erik Melén, Gerard H. Koppelman

“…Methods In the population-based BAMSE (Sweden), PIAMA (Netherlands) and MAAS (UK) birth cohorts, we analysed the association of forced expiratory volume in 1 s (FEV1), forced vital capacity (FVC), FEV1/FVC and forced expiratory volume at 75% of FVC at age 8 years with asthma onset and persistence in adolescence (age 12–16 years) using cohort-specific logistic regression analysis followed by meta-analysis. …”
Get full text

Epidemiology and response to the COVID-19 pandemic in the Dadaab Refugee Camp Complex, Kenya, March 2020–December 2022 by Maurice Ope, Raymond Musyoka, Abdihakim Kosar, Mohammed Osman, Abdijamal Hassan, Hussein Mohammed, Penina Munyua, Bonventure Juma, Elizabeth Hunsperger, Sofia Mohammed, John Burton, Rachel B. Eidex

“…Social distancing, symptom screening and mandatory mask usage were enforced during mass gatherings. Testing capacity was bolstered, quarantine and isolation facilities established, and vaccination initiated. …”
Get full text

Response of Hard-Bottom Macro-Zoobenthos to the Transition of a Mediterranean Mariculture Fish Plant (Mar Grande of Taranto, Ionian Sea) into an Integrated Multi-Trophic Aquacultur... by Roberta Trani, Cataldo Pierri, Antonella Schiavo, Tamara Lazic, Maria Mercurio, Isabella Coccia, Adriana Giangrande, Caterina Longo

“…This study was conducted from 2018 to 2021 in the semi-enclosed Mar Grande basin of Taranto (northern Ionian Sea), on a facility located 600 m off the coastline, with a production capacity of 100 tons per year of seabass (<i>Dicentrarchus labrax</i>) and seabream (<i>Sparus aurata</i>). …”
Get full text

Trivalent recombinant protein vaccine induces cross-neutralization against XBB lineage and JN.1 subvariants: preclinical and phase 1 clinical trials by Jingyun Yang, Weiqi Hong, Huashan Shi, Cai He, Hong Lei, Yanan Zhou, Hao Yang, Aqu Alu, Zimin Chen, Yun Yang, Wenhai Yu, Cong Tang, Junbin Wang, Bai Li, Qing Huang, Jiong Li, Li Yang, Wei Wang, Guobo Shen, Jinliang Yang, Zhiwei Zhao, Xiangrong Song, Zhaoming Su, Yuquan Wei, Qiangming Sun, Shuaiyao Lu, Zhenling Wang, Youchun Wang, Guangwen Lu, Weimin Li, Xiawei Wei

“…Abstract The immune escape capacities of XBB variants necessitate the authorization of vaccines with these antigens. …”
Get full text

Characterization of a Natural Accession of <i>Elymus sibiricus</i> with <i>In Situ</i> Hybridization and Agronomic Evaluation by Yizhuo Liu, Jiarui Ding, Chunfei Wu, Weiwei Song, Xinyu Zhao, Haibin Zhao, Yunfeng Qu, Hui Jin, Rui Zhang, Mingyao Li, Xinyu Yan, Liangyu Zhu, Yaqi Bao, Dianhao Liu, Xinling Li, Lei Cui, Hongjie Li, Yanming Zhang

“…Using morphological and cytogenetic methods, this study evaluated the cold tolerance, post-harvest regeneration capacity, and perennial characteristics of the <i>E. sibiricus</i> accession 20HSC-Z9 in the Harbin region of China from 2020 to 2023. …”
Get full text

Decision-making regarding place of end-of-life care for children with life-limiting and life-threatening conditions: a systematic integrative review by Ashleen Crowe, Fiona Hurley, Gemma Kiernan, Helen Kerr, Yvonne Corcoran, Jayne Price, Joanne Reid, Eileen Courtney, Tracey McConnell, Patricia McNeilly, Veronica Lambert

“…Using an iterative process of constant data comparison, four themes were identified, highlighting that (i) consideration of the child, (ii) availability and suitability of end-of-life care services, (iii) parents’ capacity and control in providing care, and (iv) family and sibling well-being were factors influencing decision-making about place of end-of-life care. …”
Get full text