Vernolactone Promotes Apoptosis and Autophagy in Human Teratocarcinomal (NTERA-2) Cancer Stem-Like Cells by Nuwanka K. Abeysinghe, Ira Thabrew, Sameera R. Samarakoon, Meran K. Ediriweera, Kamani H. Tennekoon, Varuni P. C. Pathiranage, Anuka S. Mendis

“…Effects of vernolactone on apoptosis were investigated by phase contrast light microscopic and fluorescence microscopic analysis, caspase 3/7 expression, and real-time PCR of apoptosis-associated genes p53 and Survivin. …”
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Dual targeting of breast cancer by chitosan/poly lactic-co-glycolic acid nanodelivery systems: Surface activation with folic acid/aptamers, and co-encapsulated with Sorafenib and q... by Asghar Narmani, Saeid Ganji, Maryam Amirishoar, Fatemeh Hajikarimi, Aynaz Mazandarani, Mahya Karimi, Ali Mohammadinejad, Azin Azadpour, Roghayyeh Jahedi, Elham Assadpour, Seid Mahdi Jafari

“…MTT assay indicated lower cell viability for MCF-7 cells after treatment with Apt-PLGA-So-Qu-CS-FA nanocarriers (10% cell viability after 24 h treatment with 250 nm; IC50 = 100 nm). Caspase9 and P53 genes expression was increased by 11.8 and 12.8 folds while > 5 folds reduction was observed for Bcl2 expression after treatment with Apt-PLGA-So-Qu-CS-FA. …”
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Informatization of construction production organization and operational management by V. V. Sokolnikov, M. V. Molodtsov

“…The conclusion is made about the formation of a unified information environment for the organization of construction production during construction and operational management through compatible algorithms, data structures and AWS interfaces based on a mathematical model that coordinates the algorithms for solving production problems and communication of key performers in terms of the parameters of the organization of construction production and operational management.…”
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Monitoring Guidelines for Home and Outpatient Parenteral Antibiotic Therapy by Alain Y Martel

“…Examples include dosage schedule, short and long term toxicity, stability of the antibiotics at room temperature after dilution, half-life of antibiotics, compatibility with other antibiotics or medications in the same bag and distribution methods from the supplier (pharmacy) to the patient. …”
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Microclimate monitoring in commercial tomato (Solanum Lycopersicum L.) greenhouse production and its effect on plant growth, yield and fruit quality by Jakub Šalagovič, Dorien Vanhees, Pieter Verboven, Kristof Holsteens, Bert Verlinden, Marlies Huysmans, Bram Van de Poel, Bram Van de Poel, Bart Nicolaï, Bart Nicolaï, Bart Nicolaï

“…Large greenhouses typically rely only on one central weather station per compartment to steer their internal climate, ignoring possible microclimate conditions within the greenhouse itself.MethodsIn this study, we analysed spatial variation in temperature and vapour pressure deficit in a commercial tomato greenhouse setting for three consecutive years. …”
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AGLUTINACIÓN EN LÁTEX, ELISA Y HEMOAGLUTINACIÓN: ALTERNATIVAS PARA EL DIAGNÓSTICO DE LA PARVOVIROSIS CANINA EN HECES by S Ariza, D Fuentes, VJ Vera, LC Villamil, GC Ramírez

“…Sobre una población de 71 caninos con signos compatibles con parvovirosis canina, utilizando la prueba ELISA (SNAP®) como referencia, se seleccionaron 21 caninos positivos. …”
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CADD-based discovery of novel oligomeric modulators of PKM2 with antitumor activity in aggressive human glioblastoma models by Maia Cabrera, Romina Armando, Ian Czarnowski, Patricio Chinestrad, Ramiro Blanco, Alejandra Zinni, Daniel Gómez, Diego L. Mengual Gómez, Pablo Lorenzano Menna

“…Both compounds exhibited dose-dependent antiproliferative effects in glioblastoma cell lines and induced apoptosis, as evidenced by caspase 3/7 activation. These effects were directly linked to their inhibition of PKM2 enzymatic activity, validating the proposed mechanism of action in their rational design. …”
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Functionality of bacterial communities in constructed wetlands used for water purification: influence of root components and seasonality by Yao Huang, Yao Huang, Weili An, Weili An, Tianzhu Ning, Zhiguang Ma, Yuelin Li, Ke Liu, Lingbo Ji, Lingbo Ji, Hongxiao Liu, Dafeng Hui, Hai Ren

“…Iris ensata, Canna indica, and Hymenocallis littoralis) found in constructed wetlands.ResultsOur findings revealed that the pollutant removal efficiency was higher in the wet season than in the dry season. The specific root compartment, plant species, environmental factors, and seasonality significantly influenced the bacterial composition, diversity and abundance. …”
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Modelling the Impact of Media-Induced Social Distancing on the Containment of COVID-19 in Beijing by Yinjiao Gong, Aili Wang, Jin Guo, Stacey R. Smith?

“…We propose a discrete compartment model with the fully susceptible, the media-aware susceptible, and the quarantined susceptible as three separate classes. …”
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A Review of Ammonia Combustion and Emissions Characteristics in Spark-Ignition Engines and Future Road Map by Vikas Sharma, Angad Panesar, Guillaume de Sercey, Steven Begg

“…This review article focuses on the compatibility of NH₃ as a fuel for spark-ignition (SI) engines, examining its combustion under various modes including pure NH₃ combustion, gasoline blends, NH₃/hydrogen (H₂) blends, and NH₃/natural gas blends in single or dual-fuel configurations. …”
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GM-CSF and IL-21-armed oncolytic vaccinia virus significantly enhances anti-tumor activity and synergizes with anti-PD1 immunotherapy in pancreatic cancer by Yujing Xuan, Wenyi Yan, Ruimin Wang, Xibin Wang, Yu Guo, Huilin Dun, Ziyan Huan, Lihua Xu, Ruxia Han, Xianlei Sun, Lingling Si, Nicholas R. Lemoine, Nicholas R. Lemoine, Yaohe Wang, Yaohe Wang, Pengju Wang

“…Moreover, VVL-GL21 increased the infiltration of dendritic cells (DCs), macrophages, and T cells; induced DC maturation; increased the transition from M2 to M1 macrophages; improved the formation of immune memory; prevented tumor recurrence; and effectively bolstered the immune response against tumors in multiple key immune compartments. Interestingly, mice bearing-pancreatic cancer tumors treated with VVL-GL21 showed anti-tumor immunity against lung and colon cancer tumors. …”
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Historical perspectives supporting the ambitious anesthetist aiming for zero nausea/vomiting: should one trust every consensus statement every time? by Brian A. Williams, Brian A. Williams, Christopher A. Schumacher, Ridhi Choragudi, Kelly E. Garbelotti, John M. Ludden, Daniel E. Hall, Daniel E. Hall, Daniel E. Hall

“…The described antiemetic techniques remain compatible with available opioid-free anesthetic techniques [lidocaine, acetaminophen, N-methyl-D-aspartate (NMDA) antagonists, etc.]. …”
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Differential Relationship between Intermuscular Adipose Depots with Indices of Cardiometabolic Health by Robert E. Bergia, Jung Eun Kim, Wayne W. Campbell

“…A subset of data (n=37) was analyzed for relations between muscle compartments (gastrocnemius and soleus) and cardiometabolic health. …”
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Metformin reverts aortic calcifications and elastin loss induced by an experimental metabolic syndrome by Lucas Streckwall, Nancy Martini, Claudia Sedlinsky, León Schurman, María Virginia Gangoiti, Antonio Desmond McCarthy

“…F group showed parameters compatible with MetS. Aortic tunica media from F showed decreased elastic-to-muscular layer ratio, increased collagen content and increased levels of the AGEs structure carboxymethyl-lysine. …”
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Análisis de la percepción ciudadana sobre la vivienda vacacional: el caso de Las Palmas de Gran Canaria (España) by Juan Manuel Parreño Castellano, José Ángel Hernández Luis, Claudio Moreno Medina, Antonio Ramón Ojeda

“…Los resultados permiten reconocer que, en primer lugar, la opinión de los residentes no es negativa en términos generales y, en segundo lugar, que esta percepción comparte la racionalidad económica con la que se enjuicia la actividad turística en general y está condicionada por el contacto directo con la actividad y por los intereses personales. …”
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Demand and Status of a Scientific Degree in the Non-Academic Labour Market: Regional Case by O. S. Ivanchenko, V. V. Sych

“…As a result of the study it was established that: in employment a scientific degree does not give competitive advantages to the applicant; a scientific degree has no value in the non-academic labour market, does not contribute to the advancement and occupation of a higher position in the enterprise; a scientific degree and the presence of employees with a scientific degree in the staff are considered as image-building, status marker and reputation capital of the enterprise; employers have stereotypes regarding scientific employees, which are associated both with the individual organization of labour processes and the compatibility of the scientific, creative and production process; the non-academic sector lacks a human resources strategy for dealing with such employees and a system of their incentives. …”
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Locating temporary population centers after an earthquake in urban settlements Case Study: Sabzevar City by javad jamalabadi, mahammad salmanimoghaddam, Ali shekari badi, marzieh Nodeh

“…At the same time, the points of the city, which have adequate open spaces and are compatible with the surrounding land uses, have a relatively better potential for deployment. …”
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Oridonin: A natural terpenoid having the potential to modulate apoptosis and survival signaling in cancer by Abhishek Chauhan, Hemant Joshi, Divya Kandari, Diwakar Aggarwal, Ritu Chauhan, Hardeep Singh Tuli, Arpit Mehrotra, Abhilasha Sood, Ujjawal Sharma, Darin Mansor Mathkor, Shafiul Haque, Naveen Chandra Joshi, Laurent Dufossé

“…It modulates proteins like Bax, Bcl-2, cytochrome c, and caspases, leading to DNA fragmentation. Its derivatives, such as 13p, exhibit enhanced potency by arresting the G2/M phase and targeting drug-resistant cells with minimal toxicity. …”
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A broad spectrum Shigella vaccine based on VirG53 – 353 multiepitope region produced in a cell-free system by Girmay Desalegn, Charlotte Abrahamson, K. Ross Turbyfill, Lucy Pill-Pepe, Leslie Bautista, Chitradevi S. Tamilselvi, Dylan Dunn, Neeraj Kapoor, Barbara Sullinger, Matheo Herrera, Edwin V. Oaks, Jeff Fairman, Marcela F. Pasetti

“…Seeking to refine the vaccine antigenic target and achieve scalable manufacturing compatible with Good Manufacturing Practices, we mapped linear B-cell epitopes spanning the entire VirG protein sequence by probing the immune reactivity of 10-mer peptides (overlapping 4–8 aa) with sera from Shigella-infected rhesus monkeys. …”
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Activated Human Umbilical Cord Blood Platelet-Rich Plasma Enhances the Beneficial Effects of Human Umbilical Cord Mesenchymal Stem Cells in Chemotherapy-Induced POF Rats by Jiawei Wang, Yunxiao Zhao, Fengque Zheng, Nana Ma, Rongyan Qin, Weili Qin, Bo Liu, Aiping Qin

“…The upregulation of AMH and FHSR expression and the downregulation of caspase-3 expression in granulosa cells are potential mechanisms for the recovery of ovarian function. …”
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