Remote Sensing of Sun-Induced Fluorescence in a Deep Lake: Disentangling Quenching Mechanisms Improves Relationship With Chlorophyll-a Concentration Estimates by Remika S. Gupana, Daniel Odermatt, Abolfazl Irani Rahaghi, Camille Minaudo, Mortimer Werther, Claudia Giardino, Alexander Damm

“…It increases strongly when comparing PQ (<italic>R</italic>² &#x003D; 0.72 and MAPD &#x003D; 49&#x0025;) and NPQ cases (<italic>R</italic>² &#x003D; 0.48 and MAPD &#x003D; 68&#x0025;) separately. …”
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Evaluation of pitomba extract as a natural antioxidant in fresh sausages: Effects on physicochemical properties and lipid oxidation by Taline Fiorucci da Silva, Flávia Aparecida Reitz Cardoso, Nathália Leticia Hernandez Brito, Sahra Gadia Trelha, Stefanie Calisto Casarin, Leila Larisa Medeiros Marques, Adriana Aparecida Droval

“…WHC was lowest in the sample with 1.0 % extract (A4, 74.94 g 100 g−1), while CWL increased with extract concentration, reaching 15 g 100 g−1 in A4 compared to 7.92 g 100 g−1 in A1. Lipid oxidation remained low across all samples, ranging from 0.24 to 0.32 mg MDA kg−1 after 14 days, indicating good oxidative stability. …”
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Placental growth factor modulates endothelial NO production and exacerbates experimental hepatopulmonary syndrome by Fabien Robert, Feriel Benchenouf, My Ngoc Ha, Alessandra Cuomo, Mina Ottaviani, Maxime Surbier, Raphaël Thuillet, Corinne Normand, Florent Dumont, Céline Verstuyft, Frederic Fiore, Frederic Guinut, Marc Humbert, Audrey Coilly, Emmanuel Gonzales, Olivier Sitbon, Ly Tu, Christophe Guignabert, Laurent Savale

“…Results: Circulating PlGF levels were significantly higher in patients with cirrhosis compared with healthy controls (29.4 ± 1.2 vs. 20.2 ± 0.8 pg/ml, p <0.0001), but no difference were found between patients with and without HPS. …”
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Differential Role of NKG2A/HLA-E Interaction in the Outcomes of Bladder Cancer Patients Treated with <i>M. bovis</i> BCG or Other Therapies by Inmaculada Ruiz-Lorente, Lourdes Gimeno, Alicia López-Abad, Pedro López Cubillana, Tomás Fernández Aparicio, Lucas Jesús Asensio Egea, Juan Moreno Avilés, Gloria Doñate Iñiguez, Pablo Luis Guzmán Martínez-Valls, Gerardo Server, Belén Ferri, José Antonio Campillo, María Victoria Martínez-Sánchez, Alfredo Minguela

“…<b>Results</b>: The HLA-B −21M/T genotype showed opposing results in BC patients treated with BCG or other therapies. The MM genotype, compared to MT and TT, was associated with a longer 75th-percentile overall survival (not reached vs. 68.0 ± 13.7 and 52.0 ± 8.3 months, <i>p</i> = 0.034) in BCG, but a shorter (8.0 ± 2.4 vs. 21.0 ± 3.4 and 19.0 ± 4.9 months, <i>p</i> = 0.131) survival in other treatments. …”
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Dynamic monitoring and drivers of ecological environmental quality in the Three-North region, China: Insights based on remote sensing ecological index by Leyi Zhang, Xia Li, Xiuhua Liu, Zhiyang Lian, Guozhuang Zhang, Zuyu Liu, Shuangxian An, Yuexiao Ren, Yile Li, Shangdong Liu

“…Notwithstanding an overall improvement (44.4 % of the total) consistent with the greenness compared with that of Northwest China (NWC), EEQ exhibited a marginal deterioration owing to the reduced wetness and increased heat and dryness. …”
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Identification of Inflammatory Biomarkers for Predicting Peripheral Arterial Disease Prognosis in Patients with Diabetes by Kian Draper, Ben Li, Muzammil Syed, Farah Shaikh, Abdelrahman Zamzam, Batool Jamal Abuhalimeh, Kharram Rasheed, Houssam K. Younes, Rawand Abdin, Mohammad Qadura

“…In the discovery phase the cohort was randomly split into a 70:30 ratio, and proteins with a higher mean level of expression in the DM PAD group compared to the DM non-PAD group were identified. Next, a random forest model was trained using (1) clinical characteristics, (2) a five-protein panel, and (3) clinical characteristics combined with the five-protein panel. …”
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Assessing intrinsic capacity for person‐centred HIV care: a cross‐sectional study in ageing populations in Malaysia and Hong Kong by Reena Rajasuriar, Syaza Hisham, John Son Lim, Jean Yi Cheong, Wen Ying Ho, Siew Hwei Yap, Nurul Syuhada Zulhaimi, Malinee Neelamegam, Catherine Cheung, Vivian Wong, Ruhana Che Yusof, Kejal Hasmukharay, Shahrul Bahyah Kamaruzzaman, Sharifah Faridah Syed Omar, Meng Li Chong, Pui Li Wong, Grace Chung‐Yan Lui

“…Aggregate IC scores were lower in PWH but not significantly different compared to controls, (5.4 vs. 5.6, p = 0.093) and PWH performed significantly worse than controls only in the cognitive domain. …”
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Utilization of donor CLL-1 CAR-T cells for the treatment of relapsed of acute myeloid leukemia following allogeneic hematopoietic stem cell transplantation by Meng Zhang, Meng Zhang, Xiaomei Zhang, Xiaomei Zhang, Jiaxi Wang, Wenyi Lu, Xia Xiao, Hairong Lyu, Xiaoyuan He, Yedi Pu, Juanxia Meng, Cuicui Lyu, Xinping Cao, Mingfeng Zhao, Mingfeng Zhao

“…CAR-T cells expansion was detectable in all 12 patients, with the median time of peak expansion was 9 days (range: 7-11 days). In patient 4, compared to the pre-reinfusion state, CD4+ cells at the peak of expansion showed upregulation of cell killing-related genes and memory T cell-related genes (P &lt; 0.01).ConclusionsThe CLL-1 CAR-T cells therapy derived from allogeneic donors demonstrates both safety and efficacy in the management of relapsed AML following allogeneic HSCT. …”
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Efficacy of brain stimulation therapies across psychiatric, movement, and cognitive disorders: an umbrella review synthesizing meta-analyses of randomized controlled trialsResearch... by Zhenyue Zu, Fenglan Chen, Linxi Yang, Wenzhuo Wei, Mi Zhang, Limin Huang, Ni Li, Zihan Lv, He Du, Xinrong Xue, Lijun Ma, Huixue Wang, Kai Wang, Xiaoming Li

“…SMDs were 0.44 (95% CI: 0.23, 0.65; I2 = 70%) for follow-up ≤1 month and 0.69 (95% CI: 0.43, 0.94; I2 = 84%) for follow-up >1 month. Compared to other conditions, BSTs show better therapeutic effects in treating depression, post-traumatic stress disorder, obsessive-compulsive disorder, pain, fibromyalgia, and post-stroke motor recovery. …”
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A personal sensing technology enabled service versus a digital psychoeducation control for primary care patients with depression and anxiety: a pilot randomized controlled trial by Colleen Stiles-Shields, Karen M. Reyes, Tanvi Lakhtakia, Shannon R. Smith, Olga E. Barnas, Elizabeth L. Gray, Charles J. Krause, Kaylee P. Kruzan, Mary J. Kwasny, Zara Mir, Sameer Panjwani, Steven K. Rothschild, Lisa Sánchez-Johnsen, Nathan W. Winquist, Emily G. Lattie, Nicholas B. Allen, Madhu Reddy, David C. Mohr

“…The current study: (1) developed a TES tailored for Primary Care patients with depression and/or anxiety, and (2) conducted a pilot randomized controlled trial to assess the efficacy of the TES compared to a digital psychoeducation control app. …”
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Effect of acupoint application combined with moxibustion in the treatment of postoperative constipation in patients with thoracolumbar compression fracture (艾灸联合穴位贴敷治疗胸腰椎压缩性骨折患者术后便... by WANG Tingting (王亭亭), LIU Fei (柳菲), NIE Shanshan (聂珊珊), YANG Qiujing (杨秋景), YANG Yang (杨杨)

“…The clinical efficacy and anxiety status by Visual Analogue Scale (VAS) of the two groups were compared. Results The overall effective rate in the experimental group was higher than that in the control group (90. 00% vs. 82. 00%, P＜0. 05 ). …”
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Surface processes and drivers of the snow water stable isotopic composition at Dome C, East Antarctica – a multi-dataset and modelling analysis by I. Ollivier, I. Ollivier, H. C. Steen-Larsen, B. Stenni, L. Arnaud, M. Casado, A. Cauquoin, G. Dreossi, C. Genthon, B. Minster, G. Picard, M. Werner, A. Landais

“…We observe that the mean effect of post-depositional processes over the study period enriches the snow surface in <span class="inline-formula"><i>δ</i>¹⁸</span>O by 3.0 ‰ to 3.3 ‰ and lowers the snow surface d-excess by 3.4 ‰ to 3.5 ‰ compared to the incoming precipitation isotopic signal. …”
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Cross-sectional and longitudinal associations between serum vitamin D and continuous metabolic syndrome score among children and adolescents: roles of levels of inflammation in per... by Yanyan Li, Zhuang Ma, Yan Li, Ting Xiong, Ziyang Zhang, Bingxuan Kong, Wenlong Lu, Xiu Zhao, Rongfei Zheng, Yuhan Tang, Ping Yao, Zhe Su, Yuanjue Wu, Jingfan Xiong

“…Results The RCS indicated a negative linear association between serum 25(OH)D levels and CMSRS (P-overall = 0.0066, P-nonlinear = 0.1393). GLM revealed that compared to Q1, with the quartiles of serum 25(OH)D concentrations increase, the β value ranged from 0.028 (95% CI: − 0.093, 0.037) to 0.001(95%CI: − 0.067, 0.069), and then to -0.074 (95%CI: -0.146, -0.003, P for trend = 0.0659). …”
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Bidirectional effect modifications of temperature and PM2.5 on myocardial infarction morbidity and mortality in Beijing, China from 2007 to 2021 by Piaopiao Hu, Qinghui Zeng, Jie Chang, Moning Guo, Feng Lu, Yue Qi, Zhao Yang, Pingping Jia, Qiuju Deng, Jing Liu

“…Stratified analysis revealed a greater PM2.5 effect in high temperature strata (1.049, 95 % CI: 1.029, 1.069) compared with low strata (1.007, 95 % CI: 0.993, 1.021) on MI morbidity (PZ test<0.001). …”
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Cucumeropsis mannii seed oil shields against cyclophosphamide-induced hepatorenal toxicity by modulating redox imbalance and iNOS/IL-β1 signalling in rats by Amaka Cecilia Agbara, Ejike Daniel Eze, Christian Emeka Offor, Adam Moyosore Afodun, Ezebuilo Ugbala Ekpono, Peter Chinedu Agu, Chinyere Aloke, Nkeiru Nwaamaka Ezeani, Emmanuel Orire Ikuomola, Ekom Monday Etukudo, Ilemobayo Victor Fasogbon, Angela Mumbua Musyoka, Patrick Maduabuchi Aja

“…However, combining CMSO and Omega 3 oils significantly restored the altered histology architecture, antioxidant, inflammatory markers, and liver and kidney function parameters to levels comparable to the normal group, thereby reducing the harmful effects of cyclophosphamide. …”
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Behavioral factors associated with SARS-CoV-2 infection. Results from a web-based case-control survey in the Capital Region of Denmark by Mikkel Porsborg Andersen, Christian Torp-Pedersen, Helle Collatz Christensen, Ulrik Pedersen-Bjergaard, Thomas Alexander Gerds, Amalie Lykkemark Moeller, Birgitte Lindegaard, Mille Dybdal Cajar, Florence Chia Chin Tan, Mogens Karsboel Boisen, Sebastian Moretto Krog, Rúna Nolsoee, Peter Lommer Kristensen, Thomas Broe Christensen, Maria Elisabeth Lendorf

“…Objective To study the association between behavioural factors and incidence rates of SARS-CoV-2 infection.Design Case–control web-based questionnaire study.Setting Questionnaire data were collected in the Capital Region of Denmark in December 2020 when limited restrictions were in place, while the number of daily SARS-CoV-2 cases increased rapidly.Participants 8913 cases of laboratory-confirmed SARS-CoV-2 infection were compared with two groups of controls: (1) 34 063 individuals with a negative SARS-CoV-2 test from the same date (negative controls, NCs) and 2) 25 989 individuals who had never been tested for a SARS-CoV-2 infection (untested controls, UC). …”
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Preclinical pharmaco-toxicological screening of biomimetic melanin-like nanoparticles as a potential therapeutic strategy for cutaneous melanoma by Iasmina Marcovici, Iasmina Marcovici, Raul Chioibas, Raul Chioibas, Istvan Zupko, Iulia Pinzaru, Iulia Pinzaru, Alina Moaca, Alina Moaca, Adriana Ledeti, Adriana Ledeti, Lucian Barbu-Tudoran, Lucian Barbu-Tudoran, Andreea Geamantan, Andreea Geamantan, Iasmina Predescu, Iasmina Predescu, Cristina Adriana Dehelean, Cristina Adriana Dehelean

“…After a 24 h treatment, MEL-NPs exerted a selective cytotoxicity in SH-4 and B164A5 CM cells compared to HEMa, HaCaT, and JB6 Cl 41-5a healthy skin cells, except for the concentration of 100 µg/mL, at which their viability declined under 70%. …”
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Early Outcomes from Proton Craniospinal Irradiation for Leptomeningeal Metastasis From Solid Tumors by Keng Lam, MD, Lewis F. Nasr, MD, Clark R. Andersen, MS, Kathryn E. Marqueen, MD, Jing Li, MD, PhD, Chenyang Wang, MD, Thomas H. Beckham, MD, PhD, Nazanin K. Majd, MD, PhD, Ashley E. Aaroe, MD, Monica Loghin, MD, Barbara J. O'Brien, MD, Susan L. McGovern, MD, PhD

“…Conclusions: The outcomes in our cohort are comparable to those recently reported in a phase 2 trial. …”
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Dietary steviol glycosides mixture supplementation modulates the gene expression of gut chemoreceptors and enhances the antioxidant capacity in weaned piglets by Yunxia Xiong, Zhentao He, Qiwen Wu, Hao Xiao, Shuting Cao, Xuefen Yang, Yajing Li, Zongyong Jiang, Cui Zhu, Li Wang

“…Furthermore, piglets fed a diet supplemented with 100 mg/kg SGs mixture had higher serum T-SOD, CAT, and GSH-Px activities compared with the other treatments (P < 0.05). Conclusions Therefore, our results suggest that dietary 100 ~ 150 mg/kg SGs mixture supplementation modulates gene expression of sweet taste recognition receptors and glucose transporters, while also enhancing the antioxidant capacity of weaned piglets.…”
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Altered regional brain activity and functional connectivity in relation to blood lead levels by Yi Shi, Linfeng Yan, Yang Yang, Fenfen He, Wenhao Li, Jianbin Zhang, Fang Zhao, Diya Wang, Wen Wang, Zaihua Zhao, Xuefeng Shen

“…We also examined the relationships between lead levels, FC values, and neuropsychological scores. Results Compared to the control group, individuals with high lead exposure exhibited increased ReHo in the bilateral insula and vermis and elevated DC in the left olfactory cortex. …”
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