High-Pressure Treatment in Combination with Reduced Sodium for Improving the Physicochemical Properties and Sensory Qualities of Pork Gels by Weitong Wang, Jingying Cai, Satomi Tsutsuura, Tadayuki Nishiumi

“…Rheological characteristic measurements revealed that gel strength was highest at 150 MPa (G′ = 443,000 Pa; G″ = 66,300 Pa and <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mrow><mi>t</mi><mi>a</mi><mi>n</mi><mspace width="0.166667em"></mspace><mi>δ</mi></mrow></semantics></math></inline-formula> = 0.15), which showed higher G′ and G″ values and similar <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mrow><mi>t</mi><mi>a</mi><mi>n</mi><mspace width="0.166667em"></mspace><mi>δ</mi></mrow></semantics></math></inline-formula> compared to the 0.1 MPa, 2% NaCl + 0.5% SPP condition (G′ = 334,000 Pa; G″ = 49,200 Pa; <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mrow><mi>t</mi><mi>a</mi><mi>n</mi><mspace width="0.166667em"></mspace><mi>δ</mi></mrow></semantics></math></inline-formula> = 0.148). …”
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The Use of L-Menthol in Endoscopic Transpapillary Interventions. Prospective Randomized Dual-Center Study by M. A. Anishchenko, M. A. Nazmeev, S. G. Shapovalyants, S. A. Budzinsky, A. V. Rogov, R. R. Zaynutdinov, A. S. Melnikova, E. D. Fedorov, E. N. Platonova

“…Three minutes post-irrigation, the suppression of peristaltic waves was noted in the experimental group “L”: 0 points — 63 (90 %) patients, 1 point — 6 (8.6 %) patients, compared to the control, with no change in peristalsis (p &lt; 0.05). …”
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A visual walkthrough of robotic partial mesorectal excision using the Versius surgical system by Amro Mureb

“…A recent systematic review on distal mesorectal spread and PME showed that for partial mesorectal excision, substantial overtreatment is present if a distal margin of more than 5 cm is routinely utilized; in addition, PME has good oncological results and leads to the best-fitted functional results possible for the patient's condition.1,2 Regarding the morbidity and oncological outcomes after PME, Kanso et al. showed that PME can be performed safely, with a low risk of definitive stoma and local recurrence and the survival rate that was observed, indicates that the prognosis is not altered compared with TME in the treatment of upper and some middle rectal tumour.3 Another study evaluating the oncological outcomes of PME in patients with upper and middle rectal cancer showed that PME and shorter resection margins do not jeopardize the oncological outcomes.4 Robotic colorectal surgery has gained popularity in the last few years as it overcomes most of the limitations of conventional laparoscopic surgery, especially when working in a confined, narrow pelvis. …”
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Increasing brain half-life of antibodies by additional binding to myelin oligodendrocyte glycoprotein, a CNS specific protein by Marie-Lynn Cuypers, Tom Jaspers, Jarne Clerckx, Simon Leekens, Christopher Cawthorne, Guy Bormans, Frederik Cleeren, Nick Geukens, Bart De Strooper, Maarten Dewilde

“…Anti-SARS-CoV-2 antibodies coupled with an anti-TfR VHH and two low affinity anti-MOG VHHs could be detected in brain 49 days after a single intravenous injection, which is a major improvement compared to an anti-SARS-CoV-2 antibody fused to an anti-TfR VHH which cannot be detected in brain anymore one week post treatment. …”
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Unravelling the role of secretory Immnuoglobulin-A in COVID-19: a multicentre study in nursing homes during the first wave by Rafael Bielza, Patricia Pérez, Nuria García, Laura Ballesteros-Sanabria, Rosa María Martínez, Azam Ghazi, Clara Hernando, María Victoria Rodríguez, Israel J. Thuissard, Cristina Andreu-Vázquez, José Manuel Bautista

“…“Induced” SIgA-S1 patients were more likely to be symptomatic (60.3% vs. 29%; p < 0.001) and exhibited upper respiratory tract symptoms more frequently (25.1% vs. 6.5%; p = 0.020) compared to “non-induced” patients. Patients with severe disease and duration of symptoms > 10 days had higher levels of SIgA-S1 than those with mild disease (252 vs.192.6 U/mL; p = 0.012) or duration ≤ 10 days (270.5 vs. 208.1 U/mL; p = 0.043), respectively. …”
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Exploring the benefits and prescribing informations of combining East Asian herbal medicine with conventional medicine in the treatment of rheumatoid arthritis: A systematic review... by Hee-Geun Jo, Jihye Seo, Eunhye Baek, Donghun Lee

“…EACM was associated with higher ACR responses: ACR 20 (RR: 1.2332; 95 % CI: 1.1852–1.2831, p < 0.0001), ACR 50 (RR: 1.3782; 95 % CI: 1.2936–1.4684, p < 0.0001), and ACR 70 (RR: 1.7084; 95 % CI: 1.5555–1.8762, p < 0.0001), as well as a favorable AEI (OR: 0.3977; 95 % CI: 0.3476–0.4551, p < 0.0001), indicating both better efficacy and safety compared to CM alone. These patterns were consistent across eight secondary outcomes measuring pain, inflammation, and disease activity in RA. …”
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Application of PDCA cycle in management of breast cancer patients undergoing peripherally inserted central catheter placement (PDCA循环模式在乳腺癌患者PICC置管管理中的应用)... by LI Weijia (李唯佳), CAO Hongjing (曹红京), LI Ning (李宁)

“…The incidence of complications, treatment compliance and patient satisfaction were compared between two groups. Results The incidence rates of puncture-site infection, catheter blockage and fever induced by catheter-related infection in the observation group than those in the control group, and a significant difference was found in catheter blockage rate between two groups (P＜0. 05). …”
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Effectiveness of Noninvasive Positive Pressure Ventilation Combined with Enteral Nutrition in the Treatment of Patients with Combined Respiratory Failure after Lung Cancer Surgery... by Yongjun Zhang, Lanbo Liu, Dawei Li, Dongsheng Zhou

“…The curative effects of two groups after treatment were compared, and the pulmonary function indexes (maximum expiratory pressure (PEmax), maximum midexpiratory flow rate (MMF), and maximum ventilation volume (MVV)), blood gas indexes (blood oxygen partial pressure (PaO2) and partial pressure of carbon dioxide (PaCO2)), oxygen metabolism indicators [mixed venous oxygen tension (PvO2) and central venous oxygen saturation (ScvO2)], nutritional status indicators (hemoglobin (HGB), serum albumin (ALB), and total protein (TP)), and nutritional score before and after treatment in two groups were detected, and the 6-month follow-up of the two groups was recorded. …”
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No major impact of new grape varieties on Bordeaux wine typicity: expert assessments in blind and non-blind tastings by Marc Plantevin, Sophie Tempère, Cécile Thibon, Lucile Dijkstra, Julien Lecourt, Agnès Destrac-Irvine, Cornelis van Leeuwen

“…Recently, a study investigating the typicity of 26 red varieties isolated five potential candidates (Fer Servadou, Duras, Manseng noir, Vinhão and Arinarnoa) sharing similar sensorial spaces compared to classical Bordeaux varieties. Varietal mix is strictly regulated by protected denomination of origin (PDO) rules, although these can change over time. …”
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Therapeutic Potential of Social Chatbots in Alleviating Loneliness and Social Anxiety: Quasi-Experimental Mixed Methods Study by Myungsung Kim, Seonmi Lee, Sieun Kim, Jeong-in Heo, Sangil Lee, Yu-Bin Shin, Chul-Hyun Cho, Dooyoung Jung

“…Baseline measures indicated slightly elevated levels of loneliness (UCLA Loneliness Scale, mean 27.97, SD (11.07)) and social anxiety (Liebowitz Social Anxiety Scale, mean 25.3, SD (14.19)) compared to typical university students. Significant reductions were observed as loneliness decreasing by week 2 (t175=2.55, P=.02) and social anxiety decreasing by week 4 (t175=2.67, P=.01). …”
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A new prognostic model for predicting overall survival and progression-free survival in unresectable hepatocellular carcinoma treated with the FOLFOX-HAIC regimen based on patient... by Qiuyao Zeng, Zehong Zhou, Ji Zhang, Rongzeng Cai, Hongwei Yang, Pengfei Chen, Linfang Li

“…Conclusions The model developed by our team enables risk stratification and personalized prognosis assessment for u-HCC patients undergoing FOLFOX-HAIC treatment, exhibiting superior predictive accuracy and discriminative capability compared to TNM staging.…”
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Adaptation for Staphylococcus aureus to hosts via insertion mutation in the accessory gene regulator agrC gene: decreased virulence and enhanced persistence capacity by Jiawei Chen, Yun Wu, Ying Zhu, Li Zhang, Yingchun Xu, Yali Liu

“…ATP assay results indicated that 23B maintained elevated ATP levels during the exponential phase yet exhibited reduced levels in the stationary phase when compared with 23H. Our findings suggested that the mutation in the agrC gene of S. aureus results in diminished virulence but markedly enhances persistence. …”
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Novel Procedures for Evaluating Autism Online in a Culturally Diverse Population of Children: Protocol for a Mixed Methods Pathway Development Study by Venus Mirzaei, Jeanne Wolstencroft, Georgia Lockwood Estrin, Eleanor Buckley, Shermina Sayani, Panos Katakis, Reena Anand, Tessa Squire, Eleanor Short, Paige Frankson, David Skuse, Michelle Heys

“…Sensitivity and specificity will be calculated by comparing the diagnosis of autism through CHATA with usual care. …”
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Monocyte STAT1 phosphorylation and treatment response of JAK inhibitors in chronic nonbacterial osteomyelitis by Motoshi Sonoda, Keishiro Kinoshita, Nobutaka Harada, Sungyeon Park, Shunichi Adachi, Yutaro Yada, Katsuhide Eguchi, Toshifumi Fujiwara, Makiko Kido-Nakahara, Noriko Kinjo, Masataka Ishimura, Shouichi Ohga

“…The pSTAT1 expression levels were compared with those in patients with STAT1-gain of function (STAT1-GOF) mutations (n = 5), other autoinflammatory diseases (n = 7), and healthy controls. …”
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Performance of antiretroviral drugs supply chain management and related challenges in Amhara National Regional State, Ethiopia. In the case of public health facilities found in the... by Meseret Tilahun Zeleke, Berhanemeskel Weldegerima Atsbeha, Belachew Yebeyin Melaku, Yesuneh Tefera Mekasha, Abibo Wondie Mekonen, Shimelis Dagnachew Nigatu

“…The study found that stock outs of ARV drugs were high in hospitals (16.14 %) as compared to health centers (9.2 %). Lamivudine (3TC) + Dolutegravir (DTG) + Tenofovir (TDF) (300 mg + 50 mg + 300 mg) of 30 tablets was the most frequently stocked-out drug at hospitals and health centers in about 57 % and 39 %, respectively. …”
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Process Evaluations of Interventions for the Prevention of Type 2 Diabetes in Women With Gestational Diabetes Mellitus: Systematic Review by Iklil Iman Mohd Sa'id, Natasha Hotung, Madeleine Benton, Iliatha Papachristou Nadal, Anisah Baharom, Matthew Prina, Barakatun Nisak Mohd Yusof, Kimberley Goldsmith, Samantha Birts, Ching Siew Mooi, Angus Forbes, Khalida Ismail, Boon How Chew

“…Women with GDM have an increased risk of developing type 2 diabetes mellitus (T2DM) later in life compared to those with normoglycemic pregnancy. While diabetes prevention interventions (DPIs) have been developed to delay or prevent the onset of T2DM, few studies have provided process evaluation (PE) data to assess the mechanisms of impact, quality of implementation, or contextual factors that may influence the effectiveness of the intervention. …”
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Prevalence of Diabetic Retinopathy in Patients with Cerebrovascular Accident: A Cross-sectional Study by (Col.) OK Radhakrishnan, Rutu K Rao, Varsha Manade, Swaranjali Gore, Shreya Gandhi, Khushboo Goyal, Tushar Agrawal

“…The average age of DR patients was 57.13±7.63 years, compared to 51.48±6.36 years for non DR patients. Haemorrhagic strokes were more common, occurring in 59 (59%) patients. …”
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Application of crisis management in patient complaint management in the pediatric dentistry clinic (危机管理在儿童口腔门诊投诉管理中的应用) by ZHOU Lina (周莉娜), LUO Sha (罗莎), WANG Yan (王雁)

“…The complaint rate, praise rate and satisfaction with nursing service were measured and compared between two groups. Results The complaint rate in the study group was lower than that in the control group (1. 00% vs. 5. 50%, P＜0. 05). …”
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Prevalence of carbapenemase-encoding genes carriage in patients admitted to multidisciplinary hospital in Moscow by Ni O.G., Shifman E.M., Yakovlev S.V., Bykov A.O., Gorbacheva A.A., Kruglov A.N., Belotserkovskiy B.Z., Matyushkov N.S., Galata A.A., Protsenko D.N.

“…In ICU patients the prevalence of carriage was 35.1% compared to 8.5% among ward patients. The carriage rate was the highest among patients from therapeutic wards (17.5%) and the lowest in patients from hematology wards (3.0%). …”
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The carbon cost of impaired welfare on sheep farms by L. Lanzoni, M.C. Reeves, K. Waxenberg, R. Ramsey, A.S. Atzori, J. Bell, R.M. Rees, G. Vignola, C.M. Dwyer

“…Total GHG emissions and emission intensities (EI) in kg of CO2 equivalent per kg live weight were compared across the baseline and the scenarios. Gross farm emissions and product-level EIs demonstrated divergent patterns in response to impaired welfare. …”
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