Extracellular vesicles from fifth-stage larval Angiostrongylus cantonensis upregulate cholesterol biosynthesis and suppress NLRP2-associated inflammatory responses in mouse astrocy... by Chien-Ju Cheng, Lian-Chen Wang, Lichieh Julie Chu, Kuang-Yao Chen, Ching-Yun Huang, Kuo-Lun Lan, Kuo-Yang Huang

“…Ultrastructural features showed that EVs from adult worms are smaller in size compared with those from L5. Proteomic analysis identified stage-specific proteins packaged in L5 and adult worm EVs. …”
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Characteristics and outcomes of women using emergency medical services for third-trimester pregnancy-related problems in India: a prospective observational study by Jennifer A Newberry, Corey B Bills, Elizabeth A Pirrotta, Matthew C Strehlow, G V Ramana Rao, Hyeyoun (Elise) Min, Ann E Evensen, Lawrence Leeman, S V Mahadevan

“…Time from initial call to hospital arrival was longer for rural/tribal compared with urban patients (66 min (IQR 51–84) vs 56 min (IQR 42–73), respectively, p<0.0001). …”
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Temu Kembali Citra Tenun Nusa Tenggara Timur menggunakan Esktraksi Fitur yang Robust terhadap Perubahan Skala, Rotasi, dan Pencahayaan by Budiman Baso, Nanik Suciati

“…The experiment was conducted by comparing the performance of the BoVW representation which was built using the SURF feature with Maximally Stable Extremal Regions (MSER) at the tenun image retrieval. …”
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Energy management education for persons living with long COVID-related fatigue (EMERGE): protocol of a two-parallel arms target trial emulation study in a multicentre outpatient in... by Emilia Riggi, Marco Barbero, Gian Luca Di Tanna, Ruth Hersche, Andrea Weise

“…Disease-related and productivity cost data will be collected, and a cost-effectiveness profile of the EME intervention will be compared with standard care.Ethics and dissemination Ethical approval has been obtained from the competent Swiss ethics commission.Findings will be reported (1) to the study participants; (2) to patient organisations and hospitals supporting EMERGE; (3) to funding bodies; (4) to the national and international occupational therapy community and healthcare policy; (5) will be presented at local, national, and international conferences and (6) will be disseminated by peer-review publications.…”
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Assessing the potential of germplasm collections for the management of genetic diversity: the case of the French National Cryobank by Jacques, Alicia, Duclos, Delphine, Danchin-Burge, Coralie, Mercat, Marie-José, Tixier-Boichard, Michèle, Restoux, Gwendal

“…Overall, this study proposes a framework for the assessment of germplasm collections in the service of various objectives. Compared to FAO indicators motivated by breed reconstitution, the Gini-Simpson and De indices can help to plan sampling more efficiently, whereas IDI can guide donor selection in order to manage the diversity of existing populations. …”
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Histomorphological Study of Rodenticide Poisoning: An Autopsy-based Crosssectional Study from a Tertiary Care Centre, Krishnagiri, Tamil Nadu, India by P Narmadha Priya, Jayalakshmy Pechimuthu, V Palaniappan, Teleflo Boopathy, Jeevanandham Anbazhagan, Jeevitha Muniraj

“…In a retrospective study conducted by the National Poison Information Centre, it was found that death due to rodenticide poisoning accounted for about 17.06% when compared to other pesticides, indicating a rise in the global burden of rodenticide poisoning. …”
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Dispersion modelling of particulate matter concentrations of sand product plants in a mineral complex by Y. Zehtab Yazdi, N. Mansouri, F. Atabi, H. Aghamohammadi

“…Finally, the simulated concentrations were compared with the United States Environmental Protect Agency and World Health Organization standards.FINDINGS: Results showed that hauling operations, with producing 70%, 86%, and 90% of total PM2.5, PM10 and total suspended particulates, respectively, were the major sources of dust emission in the sand and gravel product plants. …”
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Assessment of salicylic acid and potassium nitrate to mitigate frost stress in autumn-sown potato crop cv. Sutlej by Muhammad Wasim Haider, Syed Mohsin Abbas, Tanveer Hussain, Muhammad Tahir Akram, Umar Farooq, Mona S. Alwahibi, Mohamed S. Elshikh, Zaid Shakeel, Muhammad Nafees, Muhammad Rizwan, Rashid Iqbal

“…This included increased plant height by 14% and 17.6%, leaf area index by 6.3% and 26.3%, shoot biomass by 15.4% and 46.2%, crop growth rate by 16.7% and 43.3%, average tuber weight by 8.2% and 23%, tuber diameter by 6.8% and 12.2%, tuber yield by 26.1% and 46.3%, leaf angle by 16.2% and 21.6%, quantum yield of photosystem II by 20.6% and 28.2%, photosynthetically active radiations by 20.5% and 32.4%, chlorophyll content by 6.3% and 14.6%, leaf thickness by 14% and 29%, linear electron flow by 20% and 32.7%, O–2 by 6% and 14.4%, H2O2 by 11.7% and 27.6%, enzyme activities of catalase by 20.7% and 28.5%, superoxide dismutase by 28.6% and 28.5%, peroxidase by 8.3% and 13.5%, ascorbate peroxidase by 17.2% and 37.8%, total protein by 21% and 37%, proline by 36.2% and 114%, and phenolic content by 33% and 63.3% with a reduction in non-photochemical quenching by 12.7% and 29.6%, non-regulatory energy dissipation by 169.5% and 268.5%, and leaf electrolyte leakage by 57.5% and 180%, compared to KNO3 and the control, respectively. Based on the above findings, it can be concluded and recommended that 0.5 mM foliar spray of SA can be utilized on potato crop cv. …”
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Plasma phospho-tau217 as a predictive biomarker for Alzheimer’s disease in a large south American cohort by Neetesh Pandey, Zikun Yang, Basilio Cieza, Dolly Reyes-Dumeyer, Min Suk Kang, Rosa Montesinos, Marcio Soto-Añari, Nilton Custodio, Lawrence S. Honig, Giuseppe Tosto

“…Abstract Background Blood-based Alzheimer’s disease (AD) biomarkers have been increasingly employed for diagnostic, prognostic, and therapeutic monitoring purposes, due to accuracy in distinguishing AD pathophysiologic process. Compared to other p-tau isoforms, plasma p-tau217 exhibits stronger associations with AD hallmarks in CSF and brain. …”
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FUNCTIONS OF THE STATE AND LOCAL SELF-GOVERNMENT BODIES IN THE REGULATION OF FUNERAL SERVICES: ECONOMIC ASPECTS AND ENSURING SOCIAL STANDARDS by Denys Komarnytskyi, Liudmyla Sylenko, Roman Tуtykalo

“…These include: the method of dialectical materialism; the method of abstraction; methods of analysis and synthesis; the functional method; the system analysis method; the synergistic method; the comparative legal method; the method of interpretation and hermeneutics; the dogmatic method; the system analysis method; and the statistical method. …”
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Predictors of long-term symptom burden and quality of life in patients hospitalised with chest pain: a prospective observational study by Tone Merete Norekvål, Jørund Langørgen, Torbjørn Omland, Øyvind Skadberg, Kjell Vikenes, Nasir Saeed, Ole-Thomas Steiro, Hilde Lunde Tjora, Rune Oskar Bjørneklett, Vernon Vijay Singha Bonarjee, Øistein Rønneberg Mjelva, Kristin Moberg Aakre

“…Revascularised NSTEMI and UAP patients reported higher QoL scores compared with patients receiving conservative treatment. …”
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Characteristics and outcomes of out-of-hospital cardiac arrest among students under school supervision in Japan: a descriptive epidemiological study (2008–2021) by Kosuke Kiyohara, Mamoru Ayusawa, Masahiko Nitta, Takeichiro Sudo, Taku Iwami, Ken Nakata, Yuri Kitamura, Tetsuhisa Kitamura

“…The demographic characteristics, event details, and outcomes were compared across the three groups by using χ2 tests for categorical variables and one-way analyses of variance for continuous variables. …”
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PLL-g-HPA Hydrogel Loaded Human Umbilical Cord Mesenchymal Stem Cells Promote Burn Wound Healing in Rat Model by Regulating Inflammation Response by Tian L, Wang Z, Lei T, Feng L, Li Y, Wang K, Zhang Y, Zhang C, Liu J, Xing H, Ren W

“…These hydrogels exhibited low cytotoxicity at minimal concentrations while maintaining excellent moisture retention and antibacterial properties. Compared to the control group, treatment with PLL-g-HPA hydrogel in conjunction with hUC-MSCs significantly enhanced wound healing, modulated inflammatory responses, and promoted angiogenesis as well as re-epithelialization in rat models.Conclusion: The PLL-g-HPA hydrogel in conjunction with hUC-MSCs represents a promising therapeutic approach for the management of burn wounds.Keywords: rat burn model, wound healing, human umbilical cord mesenchymal stem cells, p-hydroxyphenylacetic acid grafted poly-l-ysine hydrogel…”
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Impact of school salad bars on fruit and vegetable selection, intake, and waste in Mid-Atlantic elementary schools by Melanie K. Bean, Suzanne E. Mazzeo, Lilian de Jonge, Laura Thornton, Hollie Raynor, Ashley Mendoza, Sarah Farthing, Bonnie Moore

“…Students in Salad Bar schools selected (+ .44c) and consumed (+ .36c) more FV at post, compared to baseline. Control students decreased FV selection (-.05c) with no change in intake from baseline to post. …”
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Poutníci a jejich peníze na cestě do Říma. Zamyšlení nad edicí Il Libro del pellegrino (Siena, 1382–1446) by Roman Zaoral

“…It mentions only those who deposited their cash in the hospital with the intention to withdraw it on the way back. The writer compares registered deposits with amounts intended for the pilgrimage to Rome (4–5 pounds of Prague groschens in the lower middle class and 8–10 pounds in the higher middle class) which have been entered into the memorable city book of Olomouc dated back to 1430–1492. …”
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Changes in levels of urokinase receptor and other components of fibrinolytic system in brain tissues in urokinase gene-knockout mice with B16/F10 melanoma growing together with chr... by E. M. Frantsiyants, V. A. Bandovkina, I. V. Kaplieva, N. D. Cheryarina, E. I. Surikova, I. V. Neskubina, Yu. A. Pogorelova, L. A. Nemashkalova

“…Combination of CNP with melanoma in uPA-/- mice, regardless of their gender, down-regulated levels of uPAR and PAI-I on the average by 1.5 and 2.0 times, respectively (p < 0.05), and up-regulated PAP on the average by 2.2 times (p < 0.05) compared to the levels in animals with CNP; in uPA+/+ animals, similar decline of uPAR by 3.7 times (p < 0.05) was registered only in males, and an increase of PAI-I by 2.0 times (p < 0.05) was noted in all mice.Conclusion. …”
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Association Between Liver Fibrosis and Risk of Incident Stroke and Mortality: A Large Prospective Cohort Study by Zijie Wang, Zhitao Gong, Jianshang Wen, Shanyu Zhang, Xiao Hu, Wenliang Guo, Yanghua Tian, Qi Li

“…Using the aspartate aminotransferase to platelet ratio index as an alternative score, liver fibrosis was correlated with magnified risk of intracerebral hemorrhage (HR, 3.76 [95% CI, 2.38–5.93]) and subarachnoid hemorrhage (HR, 3.05 [95% CI, 1.51–6.13]) compared with ischemic stroke (HR, 1.58 [95% CI, 1.17–2.14]). …”
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Longitudinal impact of preregistration interprofessional education on the attitudes and skills of health professionals during their early careers: a non-randomised trial with 4-yea... by Ben Darlow, Jennifer Roberts, Patrick McHugh, Melanie Brown, Eileen McKinlay, Peter Gallagher, Lesley Gray, Gordon Purdie, Christine Wilson, Sue Pullon, Louise Beckingsale, Kaye Cheetham, Ruth Crawford, Sue Floyd, Janice Handley, Jackie Herkt, Lisa Kuperus, Alison Meldrum, Margot Skinner, Rose Schwass, Julie Weaver, James Windle, Lyndie Foster-Page

“…Mixed-model analysis of covariance, adjusting for baseline characteristics, compared scores between groups at each time point. …”
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Association between weight-adjusted-waist index and long-term prognostic outcomes in cardiovascular disease patients: results from the NHANES 1999–2018 study by Hanbin Li, Wen Zhong, Hongxin Cheng, Shiqi Wang, Ran Li, Lu Wang, Chengqi He, Quan Wei

“…In the fully adjusted model, the highest quartile (WWI > 12.05 cm/√ kg) showed a higher all-cause mortality rate compared with the lowest quartile (WWI < 11.03 cm/√ kg) (HR = 1.37, 95% CI: 1.03, 1.82, P < 0.05). …”
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The prognostic value of systemic immune-inflammation index in patients with unresectable hepatocellular carcinoma treated with immune-based therapy by Tian He, Bin Xu, Lu-Na Wang, Zi-Yi Wang, Huan-Chen Shi, Cheng-Jie Zhong, Xiao-Dong Zhu, Ying-Hao Shen, Jian Zhou, Jia Fan, Hui-Chuan Sun, Bo Hu, Cheng Huang

“…ROC curves confirmed that SII had superior predictive accuracy compared to common clinical indicators, with predictive relevance even in AFP-negative patients. …”
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