The Application of Three-dimensional Shear Wave Elastography in the Detection of Inguinal Lymph Node Metastasis in Gynecological Malignancies by Yuping Shen, Jiulong Dai, Jiami Li, Man Lu

“…This approach offers a more comprehensive assessment of ultrasound elastography compared to traditional methods. …”
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The influence of scapular orientation on the medial scapula corpus angle in snapping scapula syndrome by Brittany Percin, BS, MS4, Joseph Featherall, MD, Robert Z. Tashjian, MD, Peter N. Chalmers, MD, Christopher D. Joyce, MD, Alexander J. Mortensen, MD, Heath B. Henninger, PhD

“…Statistical analyses compared the scapula type and MSCA between the reference and alternate planes within groups. …”
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Application of skin care bundles for pediatric patients with type 1 diabetes mellitus (集束化干预策略在1型糖尿病患儿皮肤管理中的应用) by WANG Qiao (王巧), YI Junli (易君丽)

“…The treatment compliance and incidence of skin problems related to insulin injection and fingerstick blood glucose monitoring were compared between two groups. Results The treatment compliance rate in the study group was higher than that in the control group(P＜0. 01). …”
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Central corneal thickness to adjust IOP measurements by A.V. Korneeva, A.V. Kuroyedov, D.N. Lovpache, I.R. Gazizova, S.Yu. Petrov, I.A. Loskutov

“…In advanced glaucoma, CCT significantly reduces, as a result, the proportion of thin corneas increases as compared with early glaucoma. Practical need to measure CCT in the course of standard ocular examination is highlighted. …”
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Impact of patient–family physician language concordance on healthcare utilisation and mortality: a retrospective cohort study of home care recipients in Ontario, Canada by Claire Kendall, Sharon Johnston, Michael Reaume, Peter Tanuseputro, Michael Pugliese, Douglas Manuel, Denis Prud'homme, Manish Sood, Ricardo Batista, Ewa Sucha, Rhiannon Roberts, Emily Rhodes, Emily Seale, Lise Bjerre, Louise Bouchard

“…The primary outcomes were Emergency Department (ED) visits, hospitalisations and death within 1 year of index home care assessment.Results Compared with non-English, non-French speakers who received language-discordant primary care, those who received language-concordant primary care experienced fewer ED visits (53.1% vs 57.5%; p<0.01), fewer hospitalisations (35.0% vs 37.6%; p<0.01) and less mortality (14.4% vs 16.6%; p<0.01) during the study period. …”
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The outcomes of residual ametropia correction by LASIK and PRK on pseudophakic eyes depending on IOL model by E.P. Gurmizov, K.B. Pershin, N.F. Pashinova, A.Yu. Tsygankov

“…Considering few large comparative studies on ametropia correction by LASIK and photorefractive keratectomy (PRK), we have performed a literature search in Russian and English databases throughout the time of existence of laser refractive surgery (about 20 years).…”
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Clinical spectrum, treatment and outcomes of the m.10197G>A mutation in MT-ND3: a case report, systematic review and meta-analysis by YuZhi Shi, Bin Chen, SongTao Niu, XinGao Wang, ZaiQiang Zhang

“…A total of 17 patients were documented as having received a combination of mitochondrial cofactor treatments. Compared with patients with LHON/LHON+, patients with LS/LS+ exhibited an exceedingly high probability of a stable or worsen outcome (93.8% vs. 33.3%, P = 0.006). …”
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A More Efficient and Safer Improved Percutaneous Pedicle Screw Insertion Technique—Trajectory Dynamic Adjustment Technique, Technical Note, and Clinical Efficacy by Hao Li, Zhiguo Ding, Bin Wei, Zhihao Ma, Jing Xie, Yonghao Tian, Lianlei Wang, Xinyu Liu, Suomao Yuan

“…However, there were no significant differences in the pre‐ and postoperative VAS score for back and leg pain and the JOA score, JOA recovery rate, intervertebral fusion rate, and complications rate between the two groups (p > 0.05). Conclusion Compared to traditional PPSF technique, TDA technique is a safer and more effective procedure which has shorter surgical time, lower radiation exposure, and lower facet joint violation rate.…”
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Pancreatic cancer cell-intrinsic transglutaminase-2 promotes T cell suppression through microtubule-dependent secretion of immunosuppressive cytokines by Anton Wellstein, Thomas Seufferlein, Alexander Kleger, Tim Eiseler, Anton Lahusen, Nora Minhöfer, Kim-André Lohse, Christine Blechner, Jessica Lindenmayer, Sabine Windhorst, Yuan-Na Lin

“…Here, we identify a cancer cell-intrinsic mechanism that contributes to a T cell-resistant phenotype and describes potential combinatorial therapy.Methods We used an unbiased screening approach of T cell resistant and sensitive murine KPC (KrasLSL-G12D/+; Trp53fl/fl; Ptf1aCre/+) PDAC cells in a three-dimensional co-culture platform with syngeneic antigen-educated T cells to identify potential cell-intrinsic drivers of T cell suppression in PDAC. Comparative transcriptomic analysis was performed to reveal promising candidates that mediate resistance to T cells. …”
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Efficacy analysis of pancreatic duct stenting in treating severe acute pancreatitis: a retrospective study by Liangping Chen, Ning Wang, Weijie Yao, Chengsi Zhao, Jiahang Tao, Gubai Ma, Chengwang Ma, Zuozheng Wang

“…The incidence of new-onset OF and new-onset systemic complications was significantly lower in the stent group compared to the control group (χ2 = 4.96, 6.65, P < 0.05). …”
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Coronil effectively inhibits the interaction of clinically relevant Omicron mutants of SARS-CoV-2 spike proteins with human ACE2 receptor by Acharya Balkrishna, Rishabh Dev, Sandeep Kumar, Anurag Varshney

“…Background: Accumulating evidence suggests that the receptor binding domain (RBD) of the SARS-CoV-2 Omicron variant has several times more binding affinity to the human angiotensin-converting enzyme 2 (ACE2) receptor compared to the RBD of the original Covid-19 strain. …”
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Reducing Greenhouse Gas Emissions and Modifying Nitrous Oxide Delivery at Stanford: Observational, Pilot Intervention Study by Eric P Kraybill, David Chen, Saadat Khan, Praveen Kalra

“…MethodsIn phase 1, total SHC (Palo Alto, California) N2O purchase data for calendar year 2022 were collected and compared (volume and cost) to total Palo Alto clinical delivery data using Epic electronic health records. …”
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Validity, reliability and clinical utility of ASSIST-Y in assessing risk of substance-related harm and dependence in Spanish male adolescents by Núria Ibáñez-Martínez, Matthew William Richard Stevens, Núria Civit-Bel, Noemí Moreno-Ferrer, Sandra Lopez-Ferré, Ana Olivares-Casado, Juame Claramunt-Mendoza, Chris Holmwood, Robert Ali

“…Scores on the various assessments were compared to establish validity (concurrent with interview, convergent with other measures), reliability, and clinical utility of ASSIST-Y. …”
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Potential Effect of Exosomes Derived from Cancer Stem Cells and MSCs on Progression of DEN-Induced HCC in Rats by Faisal A. Alzahrani, Mohammed A. El-Magd, Ahmed Abdelfattah-Hassan, Ayman A. Saleh, Islam M. Saadeldin, Eman S. El-Shetry, Abdelnaser A. Badawy, Saleh Alkarim

“…CSCs-exosomes induced a significant increase in liver relative weight and serum levels of cancer markers (AFP and GGT) and liver enzymes (ALT, AST, and ALP), intensive immunostaining for the HCC marker GST-P, and an increased number and area of tumor nodules as compared to HCC rats injected by PBS. CSCs-exosomes also decreased apoptosis (marked by downregulation of Bax and p53 and upregulation of Bcl2, and increased immunostaining of PCNA), increased angiogenetic activity (revealed by upregulation of VEGF), enhanced metastasis and invasiveness (indicated by upregulation of P13K and ERK proteins and their downstream target MMP9 and downregulation of TIMP1), and induced epithelial mesenchymal transition (marked by increased serum and hepatic level of TGFβ1 mRNA and protein). …”
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Evolution du comportement de manipulation chez les strepsirrhiniens by Louise Peckre, Anne‑Claire Fabre, Anthony Herrel, Christine Wall, Emmanuelle Pouydebat

“…A travers une approche comparative portant sur plus de 15 espèces, cette étude a également pour but de mieux comprendre les liens existants entre les facteurs écologiques et sociaux et la saisie manuelle. …”
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Intention to vaccinate against COVID-19 and adherence to non-pharmaceutical interventions against COVID-19 prior to the second wave of the pandemic in Uganda: a cross-sectional stu... by Ambrose Talisuna, Solome Okware, Rhoda K Wanyenze, Solomon Tsebeni Wafula, Innocent B Mugume, Benjamin Sensasi, Alexander Chimbaru, Richard Kabanda, Tabley Bakyaita, Jayne Byakika-Tusiime

“…This study investigated the level of adherence to COVID-19 preventive measures and intention to receive the COVID-19 vaccine among Ugandans.Design, setting and participants A nationwide cross-sectional survey of 1053 Ugandan adults was conducted in March 2021 using telephone interviews.Main outcome measures Participants reported on adherence to COVID-19 preventive measures and intention to be vaccinated with COVID-19 vaccines.Results Overall, 10.2% of the respondents adhered to the COVID-19 preventive guidelines and 57.8% stated definite intention to receive a SARS-CoV-2 vaccine. Compared with women, men were less likely to adhere to COVID-19 guidelines (Odds Ratio (OR)=0.64, 95% CI 0.41 to 0.99). …”
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Obesity and fibromyalgia are associated with Difficult-to-Treat Rheumatoid Arthritis (D2T-RA) independent of age and gender by Nicoletta Luciano, Elisa Barone, Enrico Brunetta, Alessio D’Isanto, Maria De Santis, Angela Ceribelli, Marta Caprioli, Giacomo M. Guidelli, Daniela Renna, Carlo Selmi

“…Methods We retrospectively collected demographic, clinical, and serological data on 458 patients consecutively seen for RA between January 2019 and January 2023. We compared patients fulfilling the D2T-RA criteria with the remaining RA cohort using univariate comparisons and logistic regression to determine the impact of clinical features, comorbidities on outcome variable, adjusted for confounders. …”
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The results of using micropulse cyclophotocoagulation for the treatment of patients with primary open-angle glaucoma by V.V. Egorov, A.V. Postupaev, N.V. Postupaeva

“…It was found that up to 6 months after the surgery, the group of patients under 60 years of age had a more noticeable postoperative hypotensive effect when compared to the patient group over 71 years. </p> <p> <b>Conclusion</b>: MP-CPC was an effective and safe operation for normalizing intraocular pressure in most of the patients with mild to moderate stages of POAG during the 6-month follow-up period. …”
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Determining the status of ecosystem degradation trends and their implications for ecological integrity in the southern African grassland biome by L.R. Vukeya, T.M. Mokotjomela, N. Pillay

“…., equivalent to indigenous grassland) lost 31.5 % of its cover between 1986 and 2020, while the “moderate vegetation cover” and “dense vegetation cover” (comparable to transformed grassland and associated with bush encroachment) increased by 16.8 % and 24.7 % respectively, indicating a substantial loss of biodiversity and ecosystem services. …”
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Mechanism of Bone-metastatic LUAD Cells Promoting Angiogenesis 
Through HGF/YAP Signaling Pathway by Yan DENG, Rong QIU, Xingyu LIU, Yingyang SU, Yang XUE, Yuzhen DU

“…Results BM3-CM demonstrated a more pronounced impact on the proliferation, migration, and angiogenesis of HUVEC compared to A549-CM. Bioinformatics analysis, combined with in vitro experiment, demonstrated that the secretory protein HGF was significantly elevated in BM3 cells and BM3-CM (P<0.05). …”
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