Shattering the Amyloid Illusion: The Microbial Enigma of Alzheimer’s Disease Pathogenesis—From Gut Microbiota and Viruses to Brain Biofilms by Anna Onisiforou, Eleftheria G. Charalambous, Panos Zanos

“…For decades, Alzheimer’s Disease (AD) research has focused on the amyloid cascade hypothesis, which identifies amyloid-beta (Aβ) as the primary driver of the disease. …”
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Real-time detection and monitoring of public littering behavior using deep learning for a sustainable environment by Eaman Alharbi, Ghadah Alsulami, Sarah Aljohani, Waad Alharbi, Somayah Albaradei

“…For face detection, we utilized the Haar Cascade from the OpenCV library, known for its real-time performance. …”
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RNA-Binding Proteins and Alternative Splicing Genes Are Coregulated in Human Retinal Endothelial Cells Treated with High Glucose by Hongran Zhao, Hui Kong, Bozhao Wang, Sihui Wu, Tianran Chen, Yan Cui

“…Apoptotic progress, protein phosphorylation, and NF-kappaB cascade revealed by the functional enrichment analysis of RASGs regulated by RBPs were closely related to diabetic retinopathy. …”
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Considerations for determining warm-water coral reef tipping points by P. Pearce-Kelly, A. H. Altieri, J. F. Bruno, C. E. Cornwall, M. McField, A. I. Muñiz-Castillo, J. Rocha, R. O. Setter, C. Sheppard, R. M. Roman-Cuesta, C. Yesson

“…Considering observed and projected stressor impacts, we endorse the global tipping point revision's conclusion of a global mean surface temperature (relative to pre-industrial) tipping point threshold of 1.2 <span class="inline-formula">°C</span> (range 1–1.5 <span class="inline-formula">°C</span>) and the long-term impacts of atmospheric <span class="inline-formula">CO₂</span> concentrations above 350 ppm, while acknowledging that comprehensive assessment of stressors, including ocean warming response dynamics, overshoot, and cascading impacts, have yet to be sufficiently realised. …”
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Postural imbalance without visual input is associated with specific neuropsychological deficits in older adults – results from the LIFE-adult study by Eva Grill, Andreas Zwergal, Andreas Zwergal, Dorothee Saur, Julian Klingbeil, Christopher Fricke, Florian Schöberl, Karim Felfela, Karim Felfela, Andrea Zülke, Steffi Riedel-Heller, Joseph Classen

“…Executive, memory and processing speed functions were tested by the Consortium to Establish a Registry for Alzheimer’s disease (CERAD) plus battery. Assessment of visuospatial abilities was based on the short form of the Judgment of Line Orientation Test (JLO). …”
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Vitamin C in fleshy fruits: biosynthesis, recycling, genes, and enzymes by D. Y. Tyapkina, E. Z. Kochieva, M. A. Slugina

“…Only for this pathway all the enzymes and the entire cascade of reactions have been described. For other pathways, only hypothetical metabolites are proposed and not all the catalyzing enzymes have been identified. …”
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Gene networks for use in metabolomic data analysis of blood plasma from patients with postoperative delirium by V. A. Ivanisenko, N. V. Basov, A. A. Makarova, A. S. Venzel, A. D. Rogachev, P. S. Demenkov, T.  V. Ivanisenko, M. A. Kleshchev, E. V. Gaisler, G. B. Moroz, V. V. Plesko, Y. S. Sotnikova, Y. V. Patrushev, V. V. Lomivorotov, N. A. Kolchanov, A. G. Pokrovsky

“…Within this set, 47 are assumed to be regulators of gene expression, governing the transcription of enzymes pivotal to the metabolic cascade. Complementing this, an additional assembly of 35 regulators are considered to be regulators of activity, degradation, and translocation dynamics of enzymes integral to the aforementioned pathway. …”
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Inkarrí: ¿Trilce o poemas humanos? by Pedro Granados Agüero

“…Perspectiva de estudio, la nuestra, análoga a la diglosia “Paris/ París” que percibiera Enrique Ballón en la poesía de César Vallejo (Ballón Aguirre, 2015), una vez que este ya residiera en Europa; y enfoque por el cual nos preguntamos cómo o hasta qué punto podríamos hablar, para el caso de la poesía del autor peruano, de una “desposesión y lenguaje en el exilio” (Niebylski, 2002). …”
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Type 2 Diabetes Mellitus Epidemiology of and its Complications by Julio Armando Sánchez Delgado, Nailé Edita Sánchez Lara

“…<br /><strong>Method:</strong> a descriptive, analytical, retrospective, case/control study was carried out at the César Fornet Frutos Polyclinic in the Banes municipality, from September to December 2021. …”
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La experiencia y conocimiento de los trabajadores como límite al secreto comercial by Manuel Bernet Páez, Alfredo Sierra Herrero

“…La resolución de este asunto no es sólo de naturaleza teórica, sino particularmente práctica, puesto que la mayoría de los casos de apropiación indebida de secretos comerciales son protagonizados por trabajadores que cesan en sus puestos para ocupar nuevas posiciones en otro lugar, y en el caso de que sean demandados, la principal defensa que oponen es que la supuesta información sustraída ha pasado a formar parte de sus habilidades o conocimientos personales, de ahí que puedan ejercerlas libremente. …”
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The Influence of Cell Isolation and Culturing on Natriuretic Peptide Receptors in Aortic Vascular Smooth Muscle Cells by Christine Rager, Tobias Klöpper, Sabine Tasch, Michael Raymond Whittaker, Betty Exintaris, Andrea Mietens, Ralf Middendorff

“…In addition, we hypothesize that there are sex-dependent differences in the NP/cGMP cascade in both intact tissue and cultured cells. …”
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A review on techno-economic analysis of lignocellulosic biorefinery producing biofuels and high-value products by Ronak Patel, T.S. Rajaraman, Paresh H. Rana, Nikita J. Ambegaonkar, Sanjay Patel

“…Circular Bioeconomy (CBE) has gained momentum in recent years as an alternative to conventional energy sources. Cascaded use of wastes and residues has been seen as an attractive option with low environmental impact. …”
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Exploring Disparities in Gill Physiological Responses to NaHCO₃-Induced Habitat Stress in Triploid and Diploid Crucian Carp (<i>Carassius auratus</i>): A Comprehensive I... by Shicheng Han, Lin Han, Fangying Yuan, Wenzhi Liu, Jing Wang, Xiaofeng Jin, Yanchun Sun

“…Transcriptomic data indicate differential expression of genes associated with nitrogen metabolism, complement and coagulation cascades, IL-17 signaling pathways, and Toll-like receptor signaling pathways. …”
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Artificial Visual System for Stereo-Orientation Recognition Based on Hubel-Wiesel Model by Bin Li, Yuki Todo, Zheng Tang

“…A classical explanation for the mechanism of two-dimensional orientation selectivity within the primary visual cortex is based on the Hubel-Wiesel model, a cascading neural connection structure. The local-to-global information aggregation thought within the Hubel-Wiesel model not only contributed to neurophysiology but also inspired the development of computer vision fields. …”
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Overview of systematic reviews on strategies to improve treatment initiation, adherence to antiretroviral therapy and retention in care for people living with HIV: part 1 by Lehana Thabane, Shari Margolese, Lawrence Mbuagbaw, Beth Rachlis, Winston Husbands, Carmen Logie, Marek Smieja, Elizabeth Alvarez, Daeria O Lawson, Anisa Hajizadeh, Annie Wang, Dominik Mertz, Anita C Benoit, Lisa Puchalski Ritchie, Babalwa Zani

“…Digital, mixed and peer/community-based interventions were reported to be effective across the continuum of care.Conclusions Interventions along the care cascade are mostly focused on adherence and do not sufficiently address all vulnerable populations.…”
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Genomic Diversity and Potential Transmission and Persistence of Salmonella in the Cambodian Vegetable Supply Chain by Abimel Salazar, Navin Sreng, Chanthol Peng, Yehzi Fu, Erin M. Nawrocki, Taejung Chung, Jessie Vipham, Edward G. Dudley, Jasna Kovac

“…Isolates’ relatedness was assessed based on high-quality single nucleotide polymorphisms (hqSNPs) identified within each serotype using the CFSAN SNP pipeline. Among 29 detected serotypes, Paratyphi B var. …”
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Three-Dimensional Diffusion Model in Sports Dance Video Human Skeleton Detection and Extraction by Zhi Li

“…For the combination problem of discrete skeleton points, it is proposed to take the limb parts formed between skeleton points as information carriers, construct the skeleton point association information model using vector field, and consider it as a feature, to obtain the relationship between different skeleton points by using the detection method. …”
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Proteomic and serologic assessments of responses to mRNA-1273 and BNT162b2 vaccines in human recipient sera by Thomas E. Hickey, Uma Mudunuri, Heidi A. Hempel, Troy J. Kemp, Nancy V. Roche, Keyur Talsania, Brian A. Sellers, James M. Cherry, Ligia A. Pinto

“…Thirty markers that contributed most to the model were associated with complement cascade and activation; IL-17, TNFR pro-apoptotic, and PI3K signaling; and cell cycle progression.DiscussionThese results demonstrate the utility of proteomics to evaluate correlates or predictors of serological responses to SARS-CoV-2 vaccination.…”
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Accumulation of advanced oxidation protein products aggravates bone-fat imbalance during skeletal aging by Yu-Sheng Huang, Jia-Wen Gao, Rui-Feng Ao, Xin-Yu Liu, Di-Zheng Wu, Jun-Long Huang, Chen Tu, Jing-Shen Zhuang, Si-Yuan Zhu, Zhao-Ming Zhong

“…The translational potential of this article: Reducing AOPPs accumulation and its cascading effects on MSCs might be an attractive strategy for delaying skeletal aging.…”
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Predicting the risk of gastroparesis in critically ill patients after CME using an interpretable machine learning algorithm – a 10-year multicenter retrospective study by Yuan Liu, Songyun Zhao, Wenyi Du, Wei Shen, Ning Zhou

“…BackgroundGastroparesis following complete mesocolic excision (CME) can precipitate a cascade of severe complications, which may significantly hinder postoperative recovery and diminish the patient’s quality of life. …”
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