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  1. 5461

    Significant Ionospheric Hole and Equatorial Plasma Bubbles After the 2022 Tonga Volcano Eruption by Ercha Aa, Shun‐Rong Zhang, Philip J. Erickson, Juha Vierinen, Anthea J. Coster, Larisa P. Goncharenko, Andres Spicher, William Rideout

    Published 2022-07-01
    “…The main results are as follows: (a) A significant local ionospheric hole of more than 10 TECU depletion was observed near the epicenter ∼45 min after the eruption, comprising of several cascading TEC decreases and quasi‐periodic oscillations. …”
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  2. 5462

    Ethnomedicinal, Pharmacological, and Phytochemical Overview of Diplazium esculentum by Abhishek Singh

    Published 2025-01-01
    “…Mechanistic insights delve into molecular pathways elucidating the interactions of D. esculentum bioactives with cellular targets and signalling cascades. Furthermore pharmacokinetic considerations shed light on the absorption distribution metabolism and excretion ADME profiles of its constituents providing critical insights into their bioavailability and pharmacological efficacy. …”
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  3. 5463

    Fast Hadamard-Encoded 7T Spectroscopic Imaging of Human Brain by Chan Hong Moon, Frank S. Lieberman, Hoby P. Hetherington, Jullie W. Pan

    Published 2025-01-01
    “…., N-acetyl aspartate, creatine, and choline), uses cascaded multi-slice RF excitation pulses to minimize the chemical shift dispersion error. …”
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  4. 5464

    Involvement of p38 MAPK and MAPKAPK2 in promoting cell death and the inflammatory response to ischemic stress associated with necrotic glioblastoma by Soo Yeon Kim, Miaolu Tang, Stephen Y. Chih, Jessica Sallavanti, Yan Gao, Zhiqiang Qiu, Hong-Gang Wang, Wei Li

    Published 2025-01-01
    “…MK2) signaling axis and the unfolded protein response signaling components activating transcription factor 4 (ATF4) and inositol-requiring enzyme 1 (IRE1α) in driving ischemic tumor cell death. This signaling cascade was further potentiated by RAS or PI3K activation under ischemic conditions, contributing to the inflammatory gene expression response. …”
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  5. 5465

    The role of Latin America medicinal plants in wound healing by Mariana Sánchez-Ramos, Andrea Ruiz-Betancourt, Stephany Abigail Tadeo-Cuenca, Angélica Román-Guerrero, María Crystal Columba-Palomares, Araceli Guerrero-Alonso, Antonio Bernabé-Antonio, Deyanira Ojeda-Ramírez, Francisco Cruz-Sosa

    Published 2025-01-01
    “…At a biological level, wound healing involves a complex mechanism in which the immune system and cellular biochemical cascades intervene in a coordinated manner, whose development occurs in stages such as inflammation, proliferation, and remodeling. …”
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  6. 5466

    Effects of exercise training on nigrostriatal neuroprotection in Parkinson’s disease: a systematic review by Shahid Ishaq, Iqbal Ali Shah, Shin-Da Lee, Shin-Da Lee, Bor-Tsang Wu

    Published 2025-01-01
    “…Various exercise training regimens, administered 5 days per week for 6.5 weeks, were applied to MPTP, 6-OHDA, and PFF-α-synuclein-induced PD animal models.ResultsExercise training was found to downregulate the inflammatory pathway by attenuating α-synuclein aggregation, inhibiting the TLR/MyD88/IκBα signaling cascade and NF-κB phosphorylation, and decreasing pro-inflammatory cytokines IL-1β and TNF-α while increasing anti-inflammatory cytokines IL-10 and TGF-β within the nigrostriatum. …”
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  7. 5467
  8. 5468
  9. 5469

    'Giustizia fatta': observations sur un registre des condamnés à mort (1471–1764) de la bibliothèque de Beccaria by Pierre Musitelli

    Published 2024-11-01
    “…The archives of Cesare Beccaria (1738–1794) contain an unedited manuscript register, written in Italian by several anonymous hands, and titled Elenco dei giustiziati in Milano. …”
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  10. 5470

    Association of Alzheimer’s and Lewy body disease pathology with basal forebrain volume and cognitive impairment by Julia Schumacher, Stefan Teipel, Alexander Storch

    Published 2025-01-01
    “…Associations of regional volumes with pathological markers (Braak stage, CERAD score, and McKeith criteria for LB pathology) and cognitive performance were assessed using Bayesian statistical methods. …”
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  11. 5471

    Catastrophic and violent tornadoes: a detailed review of physical-mathematical models by Sergey A. Arsen’yev, Lev V. Eppelbaum

    Published 2024-11-01
    “…When a gravity wave reaches a thunderstorm supercell that has already formed inside the atmospheric front, it is captured by the supercell because upward air movements destroy its inversion. …”
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  12. 5472

    Plan individual de ajustes razonables para la inclusión de estudiantes con discapacidad by Gloria Elena Gutiérrez Rodríguez, Yalitza Isabel Hernández Rodiño

    Published 2025-01-01
    “… El objetivo de esta investigación consistió en analizar los aportes de la aplicación del modelo plan individual de ajustes razonables (PIAR) al fortalecimiento de la inclusión de los estudiantes con discapacidad del grado octavo en el área de Ciencias Sociales del Colegio Nuestra Señora de Fátima en la ciudad de Valledupar, Cesar. El estudio se llevó a cabo bajo el paradigma sociocrítico y enfoque cualitativo, y se enmarcó en la investigación acción. …”
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  13. 5473

    FNDC5/irisin mitigates the cardiotoxic impacts of cancer chemotherapeutics by modulating ROS-dependent and -independent mechanisms by Manish Kumar, Abhishek Singh Sengar, Anushree Lye, Pranesh Kumar, Sukhes Mukherjee, Dinesh Kumar, Priyadip Das, Suvro Chatterjee, Adele Stewart, Biswanath Maity

    Published 2025-03-01
    “…Intriguingly, we identified two parallel signaling cascades impacted by FNDC5 in cardiomyocytes: the ROS-driven intrinsic mitochondrial apoptosis pathway and the ROS-independent Ataxia Telangiectasia and Rad3-Related Protein (ATR)/Checkpoint Kinase 1 (Chk1) pathway. …”
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  14. 5474

    Application and effect mechanism of electrical nerve stimulation modulation technology in rehabilitation therapy following spinal cord injury by LIU Wenhui, SUN Wenting, HU Naichong, LI Yanpi, ZHAO Jingjun

    Published 2024-01-01
    “…The mechanism of action of the electrical nerve stimulation modulation technique for SCI may be related to modulating neural excitability,thus promoting the reconstruction of neural circuits and facilitating the cascade inflammatory response. Additionally,the technique has been observed to modulate synaptic plasticity,which may contribute to the regeneration and repair of nerve tissue. …”
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  15. 5475

    A review of the Bovis Calculus’s intervention mechanism and clinical application in ischemic stroke by Ke Xu, Bowen Deng, Tongtong Jia, Mihong Ren, Hai Chen, Jing Zhang, Jinlin Guo, Yong Li, Jian Wang

    Published 2025-01-01
    “…Additionally, the efficacy of BC in treating cerebral ischemia/reperfusion injury (CI/RI) is certain, particularly due to the components of bile pigments, bile acids, and amino acids that can interfere with the enzymatic cascade reaction of CI/RI through multiple components, targets, and pathways. …”
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  16. 5476

    Relationship of Serum IL-12 to Inflammation, Hematoma Volume, and Prognosis in Patients With Intracerebral Hemorrhage by Yazhao Zhang, Yanan Tian, Jianhui Wei, Yi Xiang

    Published 2022-01-01
    “…Objective. Inflammatory cascades and hematomas after intracerebral hemorrhage (ICH) cause brain tissue and neuronal damage. …”
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  17. 5477

    The Tools for Integrated Management of Childhood Illness (TIMCI) study protocol: a multi-country mixed-method evaluation of pulse oximetry and clinical decision support algorithms by Fenella Beynon, Hélène Langet, Leah F. Bohle, Shally Awasthi, Ousmane Ndiaye, James Machoki M’Imunya, Honorati Masanja, Susan Horton, Maymouna Ba, Silvia Cicconi, Mira Emmanuel-Fabula, Papa Moctar Faye, Tracy R. Glass, Kristina Keitel, Divas Kumar, Gaurav Kumar, Gillian A. Levine, Lena Matata, Grace Mhalu, Andolo Miheso, Deusdedit Mjungu, Francis Njiri, Elisabeth Reus, Michael Ruffo, Fabian Schär, Kovid Sharma, Helen L. Storey, Irene Masanja, Kaspar Wyss, Valérie D’Acremont, TIMCI Collaborator Group

    Published 2024-12-01
    “…The Tools for Integrated Management of Childhood Illness (TIMCI) project aims to support healthcare providers to identify and manage severe illness, whilst promoting resource stewardship, by introducing pulse oximetry and clinical decision support algorithms (CDSAs) to primary care facilities in India, Kenya, Senegal and Tanzania. …”
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  18. 5478

    MASFNet: Multi-level attention and spatial sampling fusion network for pine wilt disease trees detection by Dong Ren, Meng Li, Ziyu Hong, Li Liu, Jingfeng Huang, Hang Sun, Shun Ren, Pan Sao, Wenbin Wang, Jingcheng Zhang

    Published 2025-01-01
    “…Experiments were conducted using seven different models (Faster R-CNN, Cascade R-CNN, CenterNet, FCOS, YOLOX, YOLOv7, and MASFNet), with mean average precision (mAP50) ranging from 0.717 to 0.885. …”
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  19. 5479

    Research on CSI feedback and precoding in FDD cell-free massive MIMO systems by ZHANG Dekun, BAI Baoming

    Published 2024-12-01
    “…During the downlink scheduling phase, real-time multi-user interference elimination precoding within clusters was designed on the basis of the signal-to-leakage-and-noise ratio (SLNR) algorithm. The two were cascaded to form the optimized downlink precoding weight values for each user. …”
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  20. 5480

    Differences in influenza testing and treatment in micropolitan versus metropolitan areas in the U.S. using medicare claims data from 2010 to 2016 by Alexia Couture, F. Scott Dahlgren, Hector S. Izurieta, Richard A. Forshee, Yun Lu, Carrie Reed

    Published 2025-01-01
    “…Methods Using billing data from the Centers for Medicare and Medicaid Services for those aged 65 years and older, we estimated weekly rates of ordered rapid influenza diagnostic tests (RIDT) and antivirals (AV) among Medicare enrollees by core-based statistical areas (CBSAs) during 2010–2016. We used Negative Binomial generalized mixed models to estimate adjusted rate ratios (aRR) between MSAs and muSAs, adjusting for clustering by CBSA plus explanatory variables. …”
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