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5261
Long-term stable laser injection locking for quasi-CW applications
Published 2025-01-01“…Our scheme enables the scaled operation of injection locks, even in cascaded setups, for the distributed amplification of single frequency laser light.…”
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5262
Stepping Into an Equatorial Plasma Bubble With a Swarm Overfly
Published 2023-05-01“…By exploiting the use of ground‐based receivers of Global Navigation Satellite System (GNSS) signals in combination with the Swarm plasma density measurements, we study the irregularities in the EPB formed at ∼60°W and investigate the different scales of the irregularities and the cascading processes along the magnetic flux tubes. …”
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5263
The role of the interleukin family in liver fibrosis
Published 2025-02-01“…Among these, the interleukin family activates a complex cascade of responses, including cytokines, chemokines, adhesion molecules, and lipid mediators, playing a key role in the initiation and regulation of inflammation, as well as innate and adaptive immunity. …”
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5264
Modeling and robust control of a parallel robotic mechanism driven by linear actuators based on shape memory alloys
Published 2025-03-01“…Based on the estimated model, a cascade control (backstepping-like) is implemented on the individual actuator and the parallel device to track a desired path. …”
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5265
ATP-Binding Pocket-Targeted Suppression of Src and Syk by Luteolin Contributes to Its Anti-Inflammatory Action
Published 2015-01-01“…These results strongly suggest that luteolin may exert its anti-inflammatory action by suppressing the NF-κB signaling cascade via blockade of ATP binding in Src and Syk.…”
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5266
TB prevention activities in the WHO European Region
Published 2024-08-01“…This will require a massive scale-up of efforts and larger investments, as well as coordinated approaches and interventions across the ‘cascade’ of prevention, from the identification of target populations to the completion of treatment.…”
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5267
Atipicidades del proceso de paz con las Milicias Populares de Medellín
Published 2015-01-01“…Entre 1990 y 1994 el gobierno de César Gaviria firmó ocho acuerdos de paz, uno de ellos con las Milicias Populares de Medellín, el 26 de mayo de 1994. …”
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5268
IGF2BP3 curbed by miR-15c-3p restores disrupted lipid storage and progesterone secretion in chicken granulosa cells under oxidative stress through AKT-Raf1-ERK1/2 signaling pathway
Published 2025-02-01“…These regulatory effects were mediated through the sequential downstream signaling cascade of AKT-Raf1-ERK1/2. In conclusion, IGF2BP3 curbed by miR-15c-3p restores disrupted lipid storage and progesterone secretion in chicken granulosa cells under oxidative stress through AKT-Raf1-ERK1/2 signaling pathway. …”
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5269
A Novel Myosin Essential Light Chain Mutation Causes Hypertrophic Cardiomyopathy with Late Onset and Low Expressivity
Published 2012-01-01“…The penetrance, if we consider this borderline HCM the phenotype of the p.V79I mutation, was 40%, but the mean age of the nonpenetrant mutation carriers is 15, while the mean age of the penetrant mutation carriers is 47. …”
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5270
Exploring <i>RNF213</i> in Ischemic Stroke and Moyamoya Disease: From Cellular Models to Clinical Insights
Published 2024-12-01“…Additionally, we address the gene’s implications for disease prediction, risk assessment, and cascade screening. By integrating evidence across disciplines, this review identifies critical knowledge gaps, including the biological pathways underlying <i>RNF213</i>’s pathogenicity. …”
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5271
Distribution, Phytochemical Insights, and Cytotoxic Potential of the <i>Sesbania</i> Genus: A Comprehensive Review of <i>Sesbania grandiflora</i>, <i>Sesbania sesban</i>, and <i>Se...
Published 2025-01-01“…Extensive research on <i>S. grandiflora</i> has uncovered mechanisms such as the activation of caspase cascades and the induction of apoptosis, attributed to its rich content of flavonoids and alkaloids. …”
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5272
PhpCNF-Y transcription factor infiltrates heterochromatin to generate cryptic intron-containing transcripts crucial for small RNA production
Published 2025-01-01“…This study reveals a mechanism by which heterochromatic repeats are transcribed, initiating their own silencing by triggering a primary cascade that produces siRNAs necessary for heterochromatin nucleation.…”
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5273
Design and Optimization of the Circulatory Cell-Driven Drug Delivery Platform
Published 2021-01-01“…This review specifically covers (a) the properties of red blood cells, monocytes, macrophages, neutrophils, natural killer cells, T lymphocytes, and mesenchymal stem cells; (b) the loading strategies to balance cargo amounts and cell function balance; (c) the cascade strategies to improve cell-driven targeting delivery efficiency; and (d) the features and applications of cell membranes, artificial cells, and extracellular vesicles in cancer treatment.…”
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5274
Automatic Voltage Regulator Betterment Based on a New Fuzzy FOPI+FOPD Tuned by TLBO
Published 2024-12-01“…The proposed system combines fuzzy control theory with the Fractional Order Proportional Integral Derivative (FOPID) technique and employs cascading control theory to significantly improve reliability and robustness. …”
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5275
A Protective Role of Canonical Wnt/β-Catenin Pathway in Pathogenic Bacteria-Induced Inflammatory Responses
Published 2024-01-01“…A baseline extent of inflammation is supposed to be tightly associated with a sequence of immune-modulated processes, resulting in the protection of the host organism against pathogen invasion; however, as a matter of fact is that an uncontrolled inflammatory cascade is the main factor responsible for the host damage, accordingly suggesting a significant and indispensable involvement of negative feedback mechanism in modulation of inflammation. …”
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5276
HESS Management for Virtual Inertia, Frequency, and Voltage Support Through Off-Board EV Bidirectional Chargers
Published 2024-01-01“…This article proposes a novel control strategy to manage a hybrid energy storage system (HESS) composed of dc-link capacitors and battery, through an isolated two-stage ac–dc converter (composed of a dual active bridge resonant type dc–dc converter cascaded to a voltage source inverter), intended for off-board EVBCs. …”
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5277
Unveiling the omics tapestry of B-acute lymphoblastic leukemia: bridging genomics, metabolomics, and immunomics
Published 2025-01-01“…Immune-related pathways, such as the complement system and coagulation cascade, were also significantly enriched in patients with B-ALL. …”
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5278
SARS-CoV-2 infection of human pluripotent stem cell-derived vascular cells reveals smooth muscle cells as key mediators of vascular pathology during infection
Published 2024-12-01“…This prothrombotic state is considered a key factor in the increased risk of stroke, which is observed clinically during both acute infection and long after symptoms clear. …”
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5279
High Glucose and Lipopolysaccharide Prime NLRP3 Inflammasome via ROS/TXNIP Pathway in Mesangial Cells
Published 2016-01-01“…While inflammation is considered a central component in the development in diabetic nephropathy, the mechanism remains unclear. …”
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5280
An Integrating Approach for Genome-Wide Screening of MicroRNA Polymorphisms Mediated Drug Response Alterations
Published 2017-01-01“…In addition, harnessing the abundant high quality biological network/pathways, we evaluated the cascade distribution of tarSNP impacts. We showed that the predictions can uncover most of the known experimentally supported cases as well as provide informative candidates complementary to existing methods/tools. …”
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