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5181
Nitrogen enrichment and vascular plant richness loss reduce bryophyte richness
Published 2025-02-01“…Our results highlight novel mechanisms by which land-use intensification can affect bryophytes and suggest that a loss of vascular plant richness might have cascading effects on other taxonomic groups.…”
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5182
Battery Energy Storage Systems in Microgrids: A Review of SoC Balancing and Perspectives
Published 2024-01-01“…Moreover, in this article, we discuss alternatives to improve EMS and strategies regarding the topology of power converters, including redundancy-based topology, modular multilevel converter, cascaded-based converter, and hybrid-type systems. …”
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5183
Long-Term Dynamic Monitoring of Post-Tensioning External Tendons: Temperature Effect Evaluation
Published 2024-12-01“…On this subject, this paper presents the experimental long-term monitoring of several post-tensioning external tendons in a high-speed railway bridge in which a sectorized weighted peak-picking frequency identification procedure is proposed for frequency estimation, alongside a cascade clustering process, which allows meaningful frequency estimates to be selected. …”
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5184
Targeting the B-Cell Pathway in Lupus Nephritis: Current Evidence and Future Perspectives
Published 2013-01-01“…Several hypotheses are currently experimentally tested to further elucidate the direct induction of inflammation through interaction of the pathological autoantibodies with intrinsic glomerular components and the triggering of a complement-driven autoinflammatory cascade. B-cells have, in the last decade, emerged as a promising new therapeutic target, as biological treatments successfully attempting B-cell depletion, inhibition of B-cell proliferation and differentiation, or modulation of B-cell function have become bioengineered. …”
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5185
How Hippo Signaling Pathway Modulates Cardiovascular Development and Diseases
Published 2018-01-01“…The canonical Hippo tumor suppressor pathway in mammalian cells is primarily composed of the MST1/2-SAV1-LATS1/2-MOB1-YAP/TAZ cascade. Continuing research on this pathway has identified other factors like RASSF1A, Nf2, MAP4Ks, and NDR1/2, further enriching our knowledge of the Hippo-YAP pathway. …”
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5186
Plasma proteome fingerprint in kidney diseases
Published 2025-01-01“…These proteins are important participants of complement and coagulation cascade activation and lipid metabolism.ResultsThe revealed phosphorylated proteoforms (CFB, C4A/C4B, F2, APOB, TTR, and NRAP) were identified. …”
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5187
USP20 mediates malignant phenotypic changes in bladder cancer through direct interactions with YAP1
Published 2025-02-01“…Hippo pathway activity is controlled by the phosphorylation cascade in the MST1/2-LATS1/2-YAP1 axis, in addition to other modifications such as ubiquitination of the Hippo pathway proteins through the co-regulation of E3 ligases and deubiquitinases. …”
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5188
Assessment of Artificial Neural Networks for Hourly Solar Radiation Prediction
Published 2012-01-01“…The Four ANNs topologies were used including a generalized (GRNN), a feed-forward backpropagation (FFNN), a cascade-forward backpropagation (CFNN), and an Elman backpropagation (ELMNN). …”
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5189
Guayaramerim: a borderland marked by the Mamore River and its “cachuelas”
Published 2021-05-01“…The article describes the site where the city was built, its historical permanency, and the role played by the river and its cascades in encouraging its founding just on the borders between Bolivia and Brazil. …”
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5190
Deep Vein Thrombosis and Pulmonary Embolism Secondary to Thrombophilic Disorder: A Case Report
Published 2025-02-01“…The most common inherited thrombophilias—such as Factor V Leiden mutation, prothrombin G20210A mutation and deficiencies in protein C, protein S and antithrombin III—are a group of genetic conditions that predispose individuals to thrombotic events by influencing various factors involved in the coagulation cascade. Deep Vein Thrombosis (DVT) is a common condition that is part of venous thromboembolism disorders and represents the third most common cause of death from cardiovascular disease, following heart attacks and strokes. …”
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5191
Upper‐Atmosphere Mass Density Variations From CASSIOPE Precise Orbits
Published 2021-04-01“…In this study, TMD is estimated from the precise orbits of CAScade SmallSat and IOnospheric Polar Explorer (CASSIOPE) at one‐second time step, and the TMD variations following the February 2014 geomagnetic storm are investigated. …”
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5192
Genetic Evidence of Killer Whale Predation on White Sharks in Australia
Published 2025-01-01“…ABSTRACT Killer whales (Orcinus orca) have been documented to prey on white sharks (Carcharodon carcharias), in some cases causing localised shark displacement and triggering ecological cascades. Notably, a series of such predation events have been reported from South Africa over the last decade, with killer whales specifically targeting sharks' liver. …”
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5193
Codeine 3-O-demethylase catalyzed biotransformation of morphinan alkaloids in Escherichia coli: site directed mutagenesis of terminal residues improves enzyme expression, stability...
Published 2025-01-01“…The enzyme codeine 3-O-demethylase can transform morphinan alkaloids by O-demethylation and has been applied in single step biotransformation reactions or as part of larger biosynthetic cascade, however, the productivity for these reactions remains low and suboptimal enzyme properties could be improved. …”
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5194
Research progress on modification of hemodialysis membranes with anticoagulant properties
Published 2025-02-01“…However, when the membrane material is in contact with blood directly, plasma proteins will quickly adsorb on the surface of the membrane and bind to the glycoprotein receptors on platelets, resulting in platelet activation, coagulation cascade and complement activation. This will inevitably induce coagulation and thrombosis, threatening the health and life safety of patients. …”
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5195
A method of processing mechanical mixtures using vortex set of deep separation
Published 2018-04-01“…The method involves processing mechanical mixtures using the new physical process of the vortex effect of the confuser, the series cascade connection of technological units in the main processing line and an additional line machines: separator-constrictors, cyclonesconstrictors, overpasses, separators exhaust air that drives the indivisible particles of the mixture of the overpass with the ejector, to reuse the exhaust air. …”
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5196
A A three-phase induction motor dynamic framework regulated by predictive and intelligent optimizations.
Published 2025-01-01“…Conversely, the I-FCS-MPC uses a cascade feedback structure with an appropriately adjusted controller gain to determine the optimal set of control variables. …”
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5197
Cross-attention swin-transformer for detailed segmentation of ancient architectural color patterns
Published 2024-12-01“…These methods struggle with balancing precision and computational efficiency, especially when dealing with complex patterns and high-resolution images.MethodsTo address these limitations, we propose a novel segmentation model that integrates a hierarchical vision transformer backbone with multi-scale self-attention, cascaded attention decoding, and diffusion-based robustness enhancement. …”
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5198
Procoagulant Phospholipids and Tissue Factor Activity in Cerebrospinal Fluid from Patients with Intracerebral Haemorrhage
Published 2014-01-01“…Brain contains large amounts of tissue factor, the major initiator of the coagulation cascade. Neuronal apoptosis after intracerebral haemorrhage (ICH) leads to the shedding of procoagulant phospholipids (PPLs). …”
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5199
Neurokinin-1 Receptor Antagonist Treatment in Polymicrobial Sepsis: Molecular Insights
Published 2010-01-01“…We conclude that substance P acting via neurokinin-1 receptor in sepsis initiated signaling cascade mediated mainly by protein kinase C-α, led to NF-κB and activator protein-1 activation, and further modulated proinflammatory mediators.…”
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5200
Targeting C-Reactive Protein in Inflammatory Disease by Preventing Conformational Changes
Published 2015-01-01“…Native, pentameric CRP (pCRP) is considered to be the circulating precursor form of monomeric CRP (mCRP) that has been identified to be strongly proinflammatory. …”
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