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5101
Transcriptomic signatures of subcutaneous adipose tissue in patients with diabetes and coronary artery disease: a pilot study
Published 2025-02-01“…The main molecular pathways involved were CXCR, NOTCH, STAT, NFKB1 and FGFR pathways, which have a well-documented role in diabetes and CAD. SPI1 and MTF1 were two novel upstream transcription factors identified which have been suggested to be involved in the inflammatory cascade and insulin regulation in diabetes. …”
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5102
Phased Ions‐Release Bilayer‐Guided Bone Regeneration Membrane with Nanostructure‐Mediated Antibacterial Adhesion
Published 2025-02-01“…By harnessing distinct modes of ion delivery, Cu2+ adsorbed on the surface can be released quickly from the CSHP membrane to trigger a cascade of events including antibacterial reaction, regulating macrophage polarization, and enhancing angiogenesis. …”
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5103
Insulin-Like Growth Factor and Epidermal Growth Factor Signaling in Breast Cancer Cell Growth: Focus on Endocrine Resistant Disease
Published 2015-01-01“…It is well established that the endogenous synthesis of insulin-like growth factor (IGF) and epidermal growth factor (EGF) polypeptide growth factors are closely correlated to malignant transformation and all the steps of the breast cancer metastatic cascade. Numerous studies have demonstrated that both estrogens and growth factors stimulate the proliferation of steroid-dependent tumor cells, and that the interaction between these signaling pathways occurs at several levels. …”
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5104
1 × N All‐Logic Optical Switch Based on Polymer Platform Using Multimode Interferometer
Published 2025-01-01“…The 1 × N switch based on the generalized Mach–Zehnder interferometer (GMZI) structure reduce the footprint significantly compared with the 1 × N switch consisting of a 1 × 2 switch cascade. It is believed that 1 × N switch based on GMZI structures is a promising solution to increase integration density.…”
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5105
Global inflation: modern determinism and challenges for policy
Published 2024-06-01“…The article studies global inflation determinants, causing it in recent decades and at the present stage under the influence of cascading shocks in world economy and financial system. …”
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5106
Effect of agarose/gelatin gel addition on the pro-angiogenic potential of polyhydroxybutyrate/chitosan scaffolds
Published 2025-01-01“…Moreover, the upregulation of gene expression responsible for the activation of angiogenic cascade clearly demonstrated a positive effect of the prepared composites on angiogenesis as an essential part of new tissue formation and the regeneration process itself.…”
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5107
Diffusion rate determines balance between extinction and proliferationin birth-death processes
Published 2013-03-01“…We here study spatially extended catalyst induced growth processes.This type of process exists in multiple domains of biology, rangingfrom ecology (nutrients and growth), through immunology (antigensand lymphocytes) to molecular biology (signaling molecules initiatingsignaling cascades). Such systems often exhibit an extinction-proliferationtransition, where varying some parameters can lead to either extinctionor survival of the reactants.…”
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5108
Iron triggers TvPI4P5K proteostasis and Arf-mediated cell membrane trafficking to regulate PIP2 signaling crucial for multiple pathogenic activities of the parasitic protozoan Tric...
Published 2025-02-01“…These findings highlight that TvArf220-mediated PIP2-calcium signaling cascade regulates actin cytoskeleton and cytopathogenicity of T. vaginalis. …”
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5109
Indicadores de qualidade de vida de homens idosos de Florianópolis: um estudo descritivo
Published 2002-10-01“…A renda com a aposentadoria satisfazia as necessidades de 71,2% dos entrevistados, sendo que 59,6% eram casados. As expectativas em relação ao futuro eram de otimismo para 57,7% dos idosos. …”
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5110
KIT D816V Positive Acute Mast Cell Leukemia Associated with Normal Karyotype Acute Myeloid Leukemia
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5111
Knowledge and awareness of asbestos risk among General Practitioners: Validation of a questionnaire in an area with a high incidence of asbestos-related diseases
Published 2025-01-01“…Results: Although GPs were aware of the health hazards of asbestos (94 %) and the increased risk of mesothelioma from asbestos exposure (92.6 %), significant disparities and heterogeneity of knowledge were observed among territorial districts and by comparing Casale Monferrato district with all the others, particularly regarding asbestos exposure routes, reporting of occupational diseases, and mesothelioma latency. …”
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5112
Neurological damages in COVID‐19 patients: Mechanisms and preventive interventions
Published 2023-04-01“…Internalization of SARS‐CoV‐2 triggers ROS production and modulation of the immunological cascade which ultimately initiates the hypercoagulable state and vascular thrombosis. …”
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5113
Vitamin D Receptor, Retinoid X Receptor, Ki-67, Survivin, and Ezrin Expression in Canine Osteosarcoma
Published 2012-01-01“…Upon activation, vitamin D receptors (VDRs) combine with retinoid receptor (RXR) forming a heterodimer initiating a cascade of events. Vitamin D's antineoplastic activity and its mechanism of action in OS remain to be clearly established. …”
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5114
Turbine Airfoil Leading Edge Film Cooling Bibliography: 1972–1998
Published 2000-01-01“…Substantial progress has been made in understanding the complex nature of leading edge film cooling from airfoil cascades, simulated airfoil leading edges and environment. …”
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5115
Thermodynamic and Exergoeconomic Study of an Absorption-Compression Refrigeration Cycle Driven by a Geothermal Energy Resource
Published 2024-10-01“…This article aims to investigate thermodynamic and exergoeconomic analyses of the cascade absorption refrigeration with a vapor compression refrigeration system driven by a geothermal renewable energy source. …”
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5116
The Expanding Family of Bone Marrow Homing Factors for Hematopoietic Stem Cells: Stromal Derived Factor 1 Is Not the Only Player in the Game
Published 2012-01-01“…Moreover, the responsiveness of HSPCs to an SDF-1 gradient is enhanced by some elements of innate immunity (e.g., C3 complement cascade cleavage fragments and antimicrobial cationic peptides, such as cathelicidin/LL-37 or β2-defensin) as well as prostaglandin E2 (PGE2). …”
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5117
Targeting ferroptosis in prostate cancer management: molecular mechanisms, multidisciplinary strategies and translational perspectives
Published 2025-02-01“…Ferroptosis is a new form of regulatory cell death caused by iron-dependent lipid peroxidation, which has a dual role in PCa evolution and treatment due to the multi-omics cascade of interactions among pathways and environmental stimuli. …”
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5118
Un mundo rural en transición. La campaña bonaerense según el Primer Censo Nacional de Población de la República Argentina (1869)
Published 2016-01-01“…Si bien existen tra - bajos basados en los resultados generales, se ha abordado muy poco el estudio de la población a partir de las cédulas censales en sí mismas. Nos proponemos aquí observar la estructura de la población de la campaña bonaerense durante estos primeros tiempos de la inmigración masiva, aplicando una perspectiva comparada entre tres pueblos: San Antonio de Areco en la zona norte, Mercedes en el centro y San Vicente en el sur. …”
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5119
Nonfluent/Agrammatic PPA with In-Vivo Cortical Amyloidosis and Pick’s Disease Pathology
Published 2013-01-01“…Alzheimer’s disease (AD) (CERAD frequent/Braak Stage V) was also detected. …”
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5120
A Smart Nanomedicine Unleashes a Dual Assault of Glucose Starvation and Cuproptosis to Supercharge αPD‐L1 Therapy
Published 2025-01-01“…Such novel nanomedicine is able to induce lung cancer cell cuproptosis and PD‐L1 upregulation significantly via self‐amplified cascade reactions. Meanwhile, with a decent cancer cell membrane coating, CMGCL exhibited great biosafety, tumor‐targeted efficiency and anti‐tumor effects in LLC lung tumor‐bearing mice models. …”
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