One-carbon metabolic pathway is a novel molecular signature for CD44-positive intestinal-type gastric cancer by Seyeon Joo, Yoojin Bae, Bo Kyung Yoon, Yeonjin Je, Yuna Kim, Minki Kim, Su-Jin Shin, Sungsoon Fang, Jie-Hyun Kim

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EXPRESSION OF SURFACE MARKERS ON CD4+T-LYMPHOCYTES IN NORMAL PREGNANCY AND PRE-ECLAMPSIA by V. A. Mikhailova, Y. S. Onokhina, O. M. Ovchinnikova, M. I. Mirashvili, M. S. Zainulina, S. A. Sel’kov, D. I. Sokolov

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Association Between Platelet and Cerebral Small Vessel Disease: A Secondary Analysis Based on a Retrospective Cross‐Sectional Study in Korean Adults by Shujuan Huang, Hanbo Chen, Linbo Cai, Zhaoxi Liu, Zhanbo Yu, Yuqin Dan, Danghan Xu, Yunxuan Huang

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Overexpression of KRAS enhanced the stemness of esophageal cancer cells inhibited by overexpression of circ0043898 by Wei Wang, Yuankai Song, Shiqiang Liu, Xinming Xiong, Xin Yang

“…Results circ0043898 was overexpressed in the EC cells, and reduced stem cell markers (CD44 and CD133) and the number of stem cell spheroidization. …”
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Evaluation of the long-term memory T cell in mice after immunization with a live tularemia vaccine by A. S. Kartseva, M. V. Silkina, G. M. Titareva, T. I. Kombarova, R. I. Mironova, V. V. Firstova

“…TEM cells were identified as CD3+CD4+CD44+CD62L- and CD3+CD8+CD44+CD62L-, TCM cells as CD3+CD4+CD44+CD62L+ and CD3+CD8+CD44+CD62L+, respectively. …”
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Temporal and Severity-Dependent Alterations in Plasma Extracellular Vesicle Profiles Following Spinal Cord Injury by Jamie Cooper, Scott Tait Airey, Eric Patino, Theo Andriot, Mousumi Ghosh, Damien D. Pearse

“…These markers, traditionally associated with platelet function, may also reflect immune or reparative responses following SCI. …”
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FASN promotes the stemness of cancer stem cells and protects colorectal cancer cells from ferroptosis by inhibiting the activation of SREBP2 by Ming Wang, Fulin Ge, Cheng Wu, Binbin Su, Xiaoyu Dong, Shiping Xu, Hui Shi

“…It was upregulated in 3D spheroids and CD133+CD44+ CSCs. FASN silencing reduced spheroid formation, in vivo tumor growth, and CD133+CD44+ cells. …”
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P42 | PANCREATIC CANCER STEM CELLS AND FUNCTIONAL CHARACTERIZATION OF MIR-216A-5P

“…We evaluated their impact on the expression of CSC surface markers (CD44/CD24/CxCR4), ALDH1 activity, pluripotency- and EMT-related gene expression, and clonogenic potential. …”
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The CLIC/GEEC pathway regulates particle uptake and formation of the virus-containing compartment (VCC) in HIV-1-infected macrophages. by Kathleen Candor, Lingmei Ding, Sai Balchand, Jason E Hammonds, Paul Spearman

“…We found that internalization of particles to the VCC was independent of clathrin, but required dynamin-2. CD98 and CD44, classical markers of the CLIC/GEEC pathway, colocalized with Siglec-1 and HIV-1 particles within the VCC. …”
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Cancer Stem Cell: Target Baru Obat Antikanker by DANNY HALIM, TONO DJUWANTONO, TRI HANGGONO AHMAD

“…Therefore, optimization on protocols of cancer stem cell identification and isolation strived continously. Some molecular markers that are oftenly used as a standard on cancer stem cell isolation are CD34, CD44 and CD133. …”
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Decreased Endothelin-1 bioavailability impairs aggressiveness of gallbladder cancer cells by Jetzabel Vidal-Vidal, David Brown-Brown, Nelson Quilaqueo-Millaqueo, Gaspar Peña-Münzenmayer, Carlos Spichiger, Claudia Quezada-Monrás, Flavio Salazar-Onfray, Julio C. Tapia, Ignacio Niechi

“…Treatment also decreased the expression of EMT and stemness markers CD44 and Vimentin. Functionally, rNEP reduced cell migration, invasion, and colony formation, while SM19712 affected migration and colony formation. …”
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Isocitrate Dehydrogenase-Wildtype Glioma Adapts Toward Mutant Phenotypes and Enhanced Therapy Sensitivity Under D-2-Hydroxyglutarate Exposure by Geraldine Rocha, Clara Francés-Gómez, Javier Megías, Lisandra Muñoz-Hidalgo, Pilar Casanova, Jose F. Haro-Estevez, Vicent Teruel-Martí, Daniel Monleón, Teresa San-Miguel

“…<b>Results:</b><i>IDH</i>-wt cells exhibited faster proliferation and greater adaptability under hypoxia, while <i>IDH</i>-mut cells showed cell cycle arrest and limited growth. 2HG recapitulated <i>IDH</i>-mut features in <i>IDH</i>-wt cells, including increased apoptosis under TMZ, reduced proliferation, and altered CD24/CD44 expression. In vivo, <i>IDH</i>-wt tumors were larger and more infiltrative, while 2HG administration reduced tumor volume and promoted compact morphology. …”
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Evolution of Blood Innate Immune Cell Phenotypes Following SARS-CoV-2 Infection in Hospitalized Patients with COVID-19 by Arnaud Dendooven, Stephane Esnault, Marie Jacob, Jacques Trauet, Emeline Delaunay, Thomas Guerrier, Amali E. Samarasinghe, Floriane Mirgot, Fanny Vuotto, Karine Faure, Julien Poissy, Marc Lambert, Myriam Labalette, Guillaume Lefèvre, Julie Demaret

“…To better appreciate the role of these cells during COVID-19, changes in blood eosinophil, the neutrophil and monocyte count, and levels of surface protein markers have been reported. However, analyses at several timepoints of multiple surface markers on granulocytes and monocytes over a period of one month after a SARS-CoV-2 infection are missing. …”
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The impact of inflammatory bowel diseases on the development of atherosclerosis and cardiovascular risk by G. O. Isaev, O. Iu. Trushina, M. A. Isaikina, A. A. Bestavashvili, E. S. Zadykyan, M. V. Yurazh, Ph. Yu. Kopylov, M. H. Mnatsakanyan, V. V. Fomin

“…The study included 115 patients divided into three groups: 37 patients with Crohn’s disease (CD), 44 patients with ulcerative colitis (UC), and 34 patients in a control group without signs of IBD or other risk factors. …”
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Highlighting the Factors that Influence the Behavior of Consumers in Air Transport in Romania by IONUȚ-CLAUDIU POPA

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Single-cell and spatial transcriptomics reveal a stress-induced EMT-like epithelial subset driving immune activation in silica-injured lung by Tao Wang, Tao Wang, Tao Wang, Jianfeng Hao, Bing Li, Bing Li, Ahjol Hyraht, Jialing Wang, Jialing Wang, Henglei Xia, Qingbin Wu, Wei Gao, Congxia Chen, Chuanqing Yu, Xiuqun Gong, Ting Li, Mei Zhang, Mei Zhang, Mei Zhang, Yinghai Xie, Xinrong Tao, Xinrong Tao, Xinrong Tao

“…C0 cells co-expressed surfactant genes (Sftpc, Scgb3a2), mesenchymal markers (Vim, Mmp12), and pro-inflammatory cytokines (Ccl6, S100a8/a9), reflecting a hybrid phenotype. …”
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Fufang Duzhong Jiangu granule (FFDZ) ameliorates osteoarthritis development through maintaining subchondral bone homeostasis by Houfu Ling, Houfu Ling, Jianbo Xu, Jianbo Xu, Qinghe Zeng, Zhen Fang, Liangyan Cheng, Wenhua Yuan, Jiali Chen, Yuliang Huang, Songfeng Hu, Hongting Jin, Peijian Tong, Peijian Tong, Ke Lu, Pinger Wang

“…IntroductionOsteoarthritis (OA) is a widespread joint disorder predominantly marked by cartilage degeneration and the hardening of subchondral bone, with a lack of disease-modifying drugs for OA treatment. …”
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Enzyme/pH-triggered anticancer drug delivery of chondroitin sulfate modified doxorubicin nanocrystal by Yan Liang, Xiaoheng Fu, Chen Du, Haoran Xia, Yusi Lai, Yong Sun

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