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Problems with studying directional natural selection in humans
Published 2023-11-01“…For some genetic variants and polygenic traits, an alteration of the direction of natural selection in Europe has been documented, e. g., for those associated with an immune response and cognitive abilities. …”
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The Impact of Epigenetics on the Pathophysiology of Type 2 Diabetes and Associated Nephropathic Complications
Published 2024-12-01“…As the disease progresses, the interplay between genetic, environmental, and lifestyle factors becomes increasingly evident, leading to complications. …”
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Personality traits of women with hereditary risk for breast/ovarian cancer versus obstetric history and cancer preventive behaviors
Published 2025-01-01“…Abstract The aim of the study is to analyze the relationship between personality traits of women with hereditary predisposition to breast/ovarian cancer and their obstetric history and cancer-preventive behaviors. A total of 357 women, participants of ‘The National Program for Families With Genetic/Familial High Risk for Cancer’, were included in the study. …”
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Identification of Bacterial Lipopolysaccharide-Associated Genes and Molecular Subtypes in Autism Spectrum Disorder
Published 2025-01-01“…The interplay between bacterial components, genetic predisposition, and immune dysregulation offers new insights for understanding ASD and developing personalized interventions.Keywords: autism, bacterial metabolites, immune cell infiltration, GEO, molecular subtypes, immune responses…”
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Latest news from the bonobos: Pan paniscus myths and realities
Published 2012-12-01“…Females have high social status in the group due to female association and coalition. The society is not really characterized by female dominant but rather by co-dominance of associated females. …”
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Genome-wide association analysis of composite sleep health scores in 413,904 individuals
Published 2025-01-01“…Abstract Recent genome-wide association studies (GWASs) of several individual sleep traits have identified hundreds of genetic loci, suggesting diverse mechanisms. …”
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Identification of blood transcriptome modules associated with suicidal ideation in patients with major depressive disorder
Published 2025-01-01“…Abstract The risk of suicide in patients with major depressive disorder (MDD) poses a major concern, with studies suggesting that genetics may be a contributing factor. Although there are many transcriptomic studies on postmortem brain tissue related to suicidal behavior, the blood transcriptional mechanisms of suicidal ideation (SI) remain unknown. …”
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Expression study of Wnt/β-catenin signaling pathway associated lncRNAs in schizophrenia
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Identification of positive selection signatures associated with milk and composition traits in Murciano-Granadina and Barki
Published 2024-12-01“…Domestication and selection have significantly changed the behavioral and phenotypic traits in modern domestic animals. …”
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Resting state EEG in young children with Tuberous Sclerosis Complex: associations with medications and seizures
Published 2025-01-01“…TSC manifests behaviorally with features of autism, epilepsy, and intellectual disability. …”
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Neighborhood environment associations with cognitive function and structural brain measures in older African Americans
Published 2025-01-01“…Neighborhood characteristics were not associated with WMH. We did not find evidence that DNA methylation mediates the observed associations between neighborhood characteristics and cognitive function. …”
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Investigation of rs1746661 Polymorphism in FNDC5 Gene in Obese Patients
Published 2024-12-01“…This disease results from an imbalance between energy intake and expenditure, influenced by various factors such as behavior, diet, environment, metabolic factors, and genetics. …”
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