Caesalpinia sappan L. ethyl acetate extract regulated angiogenesis in atherosclerosis by modulating the miR-126/VEGF signalling pathway by Yue He, Chao Huang, Jingjing Chen, Weizeng Shen

“…Conclusion: This study emphasises CSEAE as a natural medicinal extract for the treatment of AS that can improve the migratory viability and reduce the apoptosis of HUVECs to maintain the health of the arterial endothelial microenvironment, while CSEAE also inhibits angiogenesis and delays plaque formation in ApoE−/− mice, suggesting that the therapeutic effect of CSEAE for AS may be related to its inhibition of neovascularisation and that its molecular mechanism may be related to the miR-126/VEGF signalling pathway.…”
Get full text

Un ensemble funéraire de l’Antiquité tardive à dépôt atypique d’âne à Woippy (Moselle) by Gaël Brkojewitsch, Olivier Putelat

“…The primary nature of the deposits is attested to; the subjects are laid on their backs, with their arms and legs outstretched, the forearms extended alongside the body or drawn over the pelvis, within a container large enough to also place material culture. …”
Get full text

The expression of MALAT1, plasma brain natriuretic peptide, and Tei index in sepsis-induced myocardial injury by Guangqing Huang, Wenzi Yang, Xu Zhao, Yong Bai, Xing Jiang, Jie Liu

“…Results In terms of general information, there were no significant differences in gender, age, BMI, mean arterial pressure, systolic pressure, diastolic pressure, respiratory rate, oxygenation index, basic diseases and infection site between the two groups (P > 0.05). …”
Get full text

Optical coherence tomography in differential diagnosis of optic neuropathy of various genesis by S.I. Zhukova, D.Yu. Samsonov, T.N. Yur’eva, T.V. Prozorova

“…</p> <p> <b>Keywords</b>: optical coherence tomography, peripapillary retinal nerve fiber layer, macular ganglion cell complex, glaucoma ischemic optic neuropathy, non-arterial ischemic opticopathy, retrobulbar neuritis, multiple sclerosis. …”
Get full text

Effects of Dexmedetomidine as an Adjuvant in Preoperative Ultrasound-Guided Internal Branch of Superior Laryngeal Nerve Block on Postoperative Sore Throat and Hemodynamics in Patie... by Chen Z, Zhang L, Lu G, Zhang Y, Zhao D, Zhao S, Zhang H, Jin Y, Zhao X, Jin Y

“…The primary outcome was the incidence of POST at 6 h after surgery.Results: Compared with the control group, preoperative US-guided iSLNB significantly reduced the incidence and severity of POST at 1 and 6 h after surgery, mitigated the incidence and severity of cough during extubation, and attenuated hemodynamic responses, including heart rate, mean arterial pressure, and rate-pressure product during intubation, 1 min after intubation, and 1 min after extubation (all P < 0.01). …”
Get full text

Mechanism study of KCMF1 promoting proliferation and NF-κB signaling transduction in colorectal cancer cells by WU Zhibai, XU Guiqin, ZHANG Li, YANG Zhaojuan, LIU Yun, JIAO Kun, CHEN Zehong, XU Chen, ZUO You, ZHENG Ningqian, YE Zhiqian, LIU Yongzhong

“…Compared with control cells, KCMF1 knockdown significantly inhibited the proliferation of HCT116 and HCT15 cells (P&lt;0.001), induced cell apoptosis (P&lt;0.001), and led to cell cycle arrest in G1 phase (P&lt;0.01). RNA-Seq analysis showed that KCMF1 was involved in the regulation of several signaling pathways, including nuclear factor-κB (NF-κB) signaling pathway. …”
Get full text

Lightweight Tea Shoot Picking Point Recognition Model Based on Improved DeepLabV3+ by HU Chengxi, TAN Lixin, WANG Wenyin, SONG Min

“…The elevated mean IoU and pixel accuracy attested to the model's capacity for precise demarcation and identification of tea shoots, even amidst intricate and varied datasets, demonstrating resilience and adaptability in pragmatic contexts.…”
Get full text

Impact of Population-Based Screening for Diabetes and Prediabetes Among 67-Year-Olds Using Point-of-Care HbA1c on Healthcare Ultilisation, Results from the VISP Cohort by Andersen JW, Høgh A, Lindholt JS, Søgaard R, Støvring H, Yderstræde KB, Sandbæk A, Dahl M

“…Jesper Winkler Andersen,1,2 Annette Høgh,1,3 Jes Sanddal Lindholt,1,3– 6 Rikke Søgaard,5 Henrik Støvring,3,7 Knud Bonnet Yderstræde,5,8 Annelli Sandbæk,9– 11 Marie Dahl1,3– 5 1Vascular Research Unit, Department of Vascular Surgery, Viborg Regional Hospital, Viborg, Denmark; 2Department of Gastroenterology, Aarhus University Hospital, Aarhus, Denmark; 3Department of Clinical Medicine, Aarhus University, Aarhus, Denmark; 4Department of Cardiothoracic and Vascular Surgery, Odense University Hospital, Odense, Denmark; 5Department of Clinical Research, University of Southern Denmark, Odense, Denmark; 6Elite Centre of Individualized Treatment of Arterial Diseases (CIMA), Odense University Hospital, Odense, Denmark; 7Department of Biomedicine, Aarhus University, Aarhus, Denmark; 8Diabetes Center, Steno, Odense, Denmark; 9Department of Public Health, Aarhus University, Aarhus, Denmark; 10Research unit of General Medical Practice, Aarhus University, Aarhus, Denmark; 11Steno Diabetes Center Aarhus, Aarhus University Hospital, Aarhus, DenmarkCorrespondence: Jesper Winkler Andersen, Vascular Research Unit, Department of Surgery, Viborg Regional Hospital, Toldbodgade 12, Viborg, 8800, Denmark, Tel +45 28118736, Email jesper.andersen@midt.rm.dkPurpose: The present study aims to evaluate the changes in healthcare utilization following population-based screening for diabetes mellitus (DM) using point-of-care HbA1c measurement in the Viborg Screening Program (VISP) cohort, which invites all 67-year-olds in Viborg, Denmark, for cardiovascular disease (CVD) and DM screening.Patients and Methods: We conducted a cohort study using data from VISP and Danish national health registers. …”
Get full text

La poésie lyrique, un outil d’unification linguistique et politique by Anne-Marie Le Baillif

“…He was also required to manage the reception of Polish ambassadors who came to Tuileries and Fontainebleau to fetch the duke of Alençon (the future king Henri III of France) as new elected polish king. The official artist Antoine Caron has left paintings and drawings of these entertainments. …”
Get full text

Resultados a corto y largo plazo tras trasplante cardíaco en pacientes con cardiopatías congénitas by Marta Molina, Elena Roselló, Manel Tauron, Juan F. Tabilo, Constanza Fernandez, Carla Gotsens, Exzequiel Pueblas, José Montiel, Sandra Casellas, Angela Irabien, Laura Corominas, Laura López, Sonia Mirabet, Antonino Ginel

“…The most frequent congenital heart disease was the transposition of great arteries. Transplanted patients with congenital heart diseases were younger, had fewer comorbidities, and a higher number of previous interventions (P < .05). …”
Get full text

Les vestiges fauniques de la rue Lecointre à Reims/Durocortorum : une carrière utilisée comme dépotoir by Frédéric Poupon

“…It is not uncommon for such faunal assemblages, especially for the remains of bovine butchery, to be attested to in the vicinity of performance sites or within the sanctuaries themselves. …”
Get full text

A two-step geospace storm as a new tool of opportunity for experimentally estimating the threshold condition for the formation of a substorm current wedge by L. F. Chernogor

“…The study, for the first time, convincingly attests to the two-step geospace storm to be the best possible solar–terrestrial event of opportunity for realizing a technique for estimating the IMF <span class="inline-formula"><i>B</i>_<i>z</i></span> component threshold for the formation of the substorm current wedge. …”
Get full text

Ultrasound investigation at examination of gastro-intestinal tract at combined trauma by A. S. Yermolov, O. A. Alekseyechkina, Ye. S. Vladimirova, G. P. Titova, V. M. Abuchina

“…Color Doppler flow mapping mode of ultrasound investigation at extensive hematomas of mesentery helps to detect thrombosis of mesenteric veins, occlusion of stem arteries that provides surgeons with essential information to choose treatment tactics, and in some cases to predict course of disease.…”
Get full text

Gas drainage and utilization in coal mines in China: History, technological advances, and prospects by Guofu LI, Chao LI, Bichuan ZHANG, Yun XU, Zheng WANG, Xianjun ZHOU

“…Concurrently this period has seen the development and extensive applications of many safe transportation technologies and devices, including water sealing of fire barriers and explosion venting devices, dry flame arresters, and explosion suppression devices through water mist/automatic powder spraying. …”
Get full text

Jinbei oral liquid for idiopathic pulmonary fibrosis: a randomized placebo-controlled trial by Aijun Zhang, Kangkang Han, Fangfang Chen, Xiao Chen, Jun Wang, Yikai Niu, Zhaoqiu Hu, Chunyan Zheng, Liping Han, Zhaoqing Meng, Liangzong Zhang, Qingcui Xu, Cuixiang Yu, Wei Zhang, Quanguo Li, Ningning Tao, Weixiang Kong, Fei Liu, Min Wang, Juanjuan Jiang, Honglin Li, LongBin Pang, Huaichen Li

“…George’s Respiratory Questionnaire (SGRQ) total score, and arterial oxygen partial pressure (PaO2) from baseline to week 26 versus placebo. …”
Get full text

Le temple polygonal de la rue Lecointre à Reims/Durocortorum by Sébastien Péchart, Frédéric Poupon

“…The diversity of fallow deer bones discovered attests to the presence of this animal, living within the territory during Gallo-Roman times. …”
Get full text

從「無感」到「五感」的環境意識啟蒙：特定場域劇場教學之批判教育學實踐 From “Indifference” to Environmental Conscientization Through Critical Sensory Pedagogy: A Critical Pedagogy Praxis in a University Site-Specifi... by 藍貝芝 Betsy Lan, 楊佳羚 Chia-Ling Yang

“…This study forms part of the broader research project “Global Youth (Digital) Citizen-Artists and their Publics: Performing for Socio-Ecological Justice,” with a specific focus on the Taiwan case study. …”
Get full text

Left ventricular global longitudinal strain is associated with filling pressure and cardiac output in an outpatient setting: Insights from CardioMEMS™ by Francisco Barbas de Albuquerque, Rita Teixeira, Tiago Pereira-da-Silva, Vera Ferreira, António Valentim Gonçalves, Rita Ilhão Moreira, Ana Teresa Timóteo, Ana Galrinho, Luísa Branco, Pedro Rio, João Alves, Sofia Barquinha, Duarte Cacela, Rui Cruz Ferreira

“…We aimed to assess whether LVGLS is associated with invasive pulmonary artery pressures (PAP) and CO in outpatients using the invasive remote monitoring CardioMEMS™ system. …”
Get full text

Development and validation of a screening tool for sepsis without laboratory results in the emergency department: a machine learning studyResearch in context by Shan Jiang, Shuai Dai, Yulin Li, Xianlong Zhou, Cheng Jiang, Cong Tian, Yana Yuan, Chengwei Li, Yan Zhao

“…Patients who were under 18 years of age, had cardiopulmonary arrest upon arrival at the ED, or had missing and abnormal medical record data were excluded. …”
Get full text

Early prediction of long COVID-19 syndrome persistence at 12 months after hospitalisation: a prospective observational study from Ukraine by Dmytro Chumachenko, Tetyana Chumachenko, Oleksii Honchar, Tetiana Ashcheulova

“…Patients who reported incomplete recovery at 1 year were characterised by a higher burden of comorbidities (Charlson index of 0.69±0.96 vs 0.31±0.51, p=0.001) and residual pulmonary consolidations (1.56±1.78 vs 0.98±1.56, p=0.034), worse blood pressure (BP) control (systolic BP of 138.1±16.2 vs 132.2±15.8 mm Hg, p=0.041), renal (estimated glomerular filtration rate of 59.5±14.7 vs 69.8±20.7 mL/min/1.73 m2, p=0.007) and endothelial function (flow-mediated dilation of the brachial artery of 10.4±5.4 vs 12.4±5.6%, p=0.048), higher in-hospital levels of liver enzymes (alanine aminotransferase (ALT) of 76.3±60.8 vs 46.3±25.3 IU/L, p=0.002) and erythrocyte sedimentation rate (ESR) (34.3±12.1 vs 28.3±12.6 mm/h, p=0.008), slightly higher indices of ventricular longitudinal function (left ventricular (LV) global longitudinal strain (GLS) of 18.0±2.4 vs 17.0±2.3%, p=0011) and higher levels of Hospital Anxiety and Depression Scale anxiety (7.3±4.2 vs 5.6±3.8, p=0.011) and depression scores (6.4±3.9 vs 4.9±4.3, p=0.022) and EFTER-COVID study physical symptoms score (12.3±3.8 vs 9.2±4.2, p&lt;0.001). …”
Get full text